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11. 发明申请

US20120007778A1 FLUIDIC CONSTRUCTS FOR ELECTRONIC DEVICES 有权
标题翻译：电子设备流体结构
公开(公告)号：US20120007778A1
公开(公告)日：2012-01-12
申请号：US12832587
申请日：2010-07-08
申请人： Amy E. Duwel , Jason O. Fiering , Douglas W. White , Mark J. Mescher , Joseph M. Bauer , John R. Lachapelle , Bryan McLaughlin , Frans Spaepen
发明人： Amy E. Duwel , Jason O. Fiering , Douglas W. White , Mark J. Mescher , Joseph M. Bauer , John R. Lachapelle , Bryan McLaughlin , Frans Spaepen
IPC分类号： H01Q3/01 , H01Q3/00 , H01H35/30
CPC分类号： H01Q3/446 , H01Q3/01
摘要： In various embodiments, an actuating mechanism is employed to displace a conductor disposed within a fluidic channel, thereby reconfiguring an electronic component.
摘要翻译：在各种实施例中，使用致动机构来置换设置在流体通道内的导体，从而重新配置电子部件。

12. 发明授权

US09180054B2 Drug delivery apparatus 有权
标题翻译：药物输送装置
公开(公告)号：US09180054B2
公开(公告)日：2015-11-10
申请号：US12986067
申请日：2011-01-06
申请人： Jason O. Fiering , Mark J. Mescher , Sharon G. Kujawa , Michael J. McKenna , William F. Sewell
发明人： Jason O. Fiering , Mark J. Mescher , Sharon G. Kujawa , Michael J. McKenna , William F. Sewell
IPC分类号： A61M11/00 , A61M31/00 , A61M5/142 , A61F11/00
CPC分类号： A61F11/002 , A61M5/14216 , A61M5/14224 , A61M5/14276 , A61M31/002 , A61M2205/0244 , A61M2210/0662 , A61M2210/0668
摘要： An implantable drug delivery apparatus for delivering a drug into a bodily fluid in a body cavity of a patient over a period of time includes a variable-volume vessel defining a working chamber for receiving a drug and recirculating a therapeutic fluid. The fluid can contain a bodily fluid, such as, for example, perilymph, and a drug. The device allows for the controlled delivery of the therapeutic fluid to a predetermined location in the bodily cavity of the patient, such as, for example, a cochlea of a human ear.
摘要翻译：一种用于在一段时间内将药物输送到患者体腔中的体液中的可植入药物递送装置包括限定用于接收药物并再循环治疗流体的工作室的可变容积容器。流体可以包含体液，例如外淋巴液和药物。该装置允许将治疗流体受控地输送到患者体腔中的预定位置，例如人耳的耳蜗。

13. 发明授权

US09293821B2 Electronic devices, such as antennas, having fluidic constructs that permit reconfiguration of the devices 有权
标题翻译：电子设备，例如天线，具有允许重新配置设备的流体结构
公开(公告)号：US09293821B2
公开(公告)日：2016-03-22
申请号：US12832587
申请日：2010-07-08
申请人： Amy E. Duwel , Jason O. Fiering , Douglas W. White , Mark J. Mescher , Joseph M. Bauer , John R. Lachapelle , Bryan Mclaughlin , Frans Spaepen
发明人： Amy E. Duwel , Jason O. Fiering , Douglas W. White , Mark J. Mescher , Joseph M. Bauer , John R. Lachapelle , Bryan Mclaughlin , Frans Spaepen
IPC分类号： H01Q1/00 , H01Q3/44 , H01Q3/01
CPC分类号： H01Q3/446 , H01Q3/01
摘要： In various embodiments, an actuating mechanism is employed to displace a conductor disposed within a fluidic channel, thereby reconfiguring an electronic component.
摘要翻译：在各种实施例中，使用致动机构来置换设置在流体通道内的导体，从而重新配置电子部件。

14. 发明申请

US20110295194A1 DRUG DELIVERY APPARATUS 有权
标题翻译：药物递送装置
公开(公告)号：US20110295194A1
公开(公告)日：2011-12-01
申请号：US12986067
申请日：2011-01-06
申请人： Jason O. Fiering , Mark J. Mescher , Sharon G. Kujawa , Michael J. McKenna , William F. Sewell
发明人： Jason O. Fiering , Mark J. Mescher , Sharon G. Kujawa , Michael J. McKenna , William F. Sewell
IPC分类号： A61M31/00 , A61M1/00
CPC分类号： A61F11/002 , A61M5/14216 , A61M5/14224 , A61M5/14276 , A61M31/002 , A61M2205/0244 , A61M2210/0662 , A61M2210/0668
摘要： An implantable drug delivery apparatus for delivering a drug into a bodily fluid in a body cavity of a patient over a period of time includes a variable-volume vessel defining a working chamber for receiving a drug and recirculating a therapeutic fluid. The fluid can contain a bodily fluid, such as, for example, perilymph, and a drug. The device allows for the controlled delivery of the therapeutic fluid to a predetermined location in the bodily cavity of the patient, such as, for example, a cochlea of a human ear.
摘要翻译：一种用于在一段时间内将药物输送到患者体腔中的体液中的可植入药物递送装置包括限定用于接收药物并再循环治疗流体的工作室的可变容积容器。流体可以包含体液，例如外淋巴液和药物。该装置允许将治疗流体受控地输送到患者体腔中的预定位置，例如人耳的耳蜗。

15. 发明授权

US07867193B2 Drug delivery apparatus 有权
标题翻译：药物输送装置
公开(公告)号：US07867193B2
公开(公告)日：2011-01-11
申请号：US11046540
申请日：2005-01-28
申请人： Michael J. McKenna , Jason O. Fiering , Mark J. Mescher , Sharon G. Kujawa , William F. Sewell , Anthony A. Mikulec
发明人： Michael J. McKenna , Jason O. Fiering , Mark J. Mescher , Sharon G. Kujawa , William F. Sewell , Anthony A. Mikulec
IPC分类号： A61M29/00 , A61M37/00 , A61M31/00 , A61N1/30
CPC分类号： A61M5/14276 , A61F11/00 , A61M5/14224 , A61M5/1723 , A61M31/002 , A61M2205/0244 , A61M2205/3379 , A61M2210/0662 , A61M2210/0668
摘要： An implantable drug delivery apparatus for delivering a drug into a bodily fluid in a body cavity of a patient over a period of time, which includes a hollow member that defines at least one lumen for facilitating a unidirectional recirculating flow of a therapeutic fluid through the lumen. The fluid can contain a bodily fluid, such as, for example, perilymph, and a drug. The apparatus also includes a pump, for example a single unidirectional pump, to control the flow rate of the therapeutic fluid through the hollow member, and an interface member in communication with at least one lumen of the hollow member. The device thus allows for the controlled delivery of the therapeutic fluid to a predetermined location in the bodily cavity of the patient, such as, for example, a cochlea of a human ear.
摘要翻译：一种可植入药物输送装置，用于将药物输送到患者体腔中的体液一段时间，该时间段包括限定至少一个内腔的中空构件，以便于治疗流体通过内腔的单向循环流动。流体可以包含体液，例如外淋巴液和药物。该装置还包括泵，例如单个单向泵，以控制通过中空构件的治疗流体的流速，以及与中空构件的至少一个内腔连通的界面构件。因此，该装置允许治疗性流体的受控输送到患者体腔中的预定位置，例如人耳的耳蜗。

16. 发明申请

US20090044619A1 DEVICES AND METHODS FOR PRODUCING A CONTINUOUSLY FLOWING CONCENTRATION GRADIENT IN LAMINAR FLOW 有权
标题翻译：在层流中产生连续流动浓度梯度的装置和方法
公开(公告)号：US20090044619A1
公开(公告)日：2009-02-19
申请号：US12043575
申请日：2008-03-06
申请人： Jason O. Fiering , Mathew Varghese
发明人： Jason O. Fiering , Mathew Varghese
IPC分类号： G01F5/00
CPC分类号： B01J19/0093 , B01F5/0641 , B01F13/0059 , B01J2219/00783 , B01J2219/00822 , B01J2219/00828 , B01J2219/00831 , B01J2219/00833 , B01J2219/0086 , B01J2219/00889 , B01L3/502776 , Y10T137/87281
摘要： The invention generally relates to combining a plurality of flow streams. In various embodiments, a first channel transports a first laminar fluid flow, a second channel transports a second laminar fluid flow, and the first and second channels enter a merging region at an acute angle to one another along separate substantially parallel planes.
摘要翻译：本发明一般涉及组合多个流动流。在各种实施例中，第一通道输送第一层流体流，第二通道输送第二层流体流，并且第一和第二通道沿独立的基本上平行的平面以彼此成锐角进入锐角。

17. 发明授权

US07837379B2 Devices for producing a continuously flowing concentration gradient in laminar flow 有权
标题翻译：用于在层流中产生连续流动的浓度梯度的装置
公开(公告)号：US07837379B2
公开(公告)日：2010-11-23
申请号：US12043575
申请日：2008-03-06
申请人： Jason O. Fiering , Mathew Varghese
发明人： Jason O. Fiering , Mathew Varghese
IPC分类号： B01F5/00
CPC分类号： B01J19/0093 , B01F5/0641 , B01F13/0059 , B01J2219/00783 , B01J2219/00822 , B01J2219/00828 , B01J2219/00831 , B01J2219/00833 , B01J2219/0086 , B01J2219/00889 , B01L3/502776 , Y10T137/87281
摘要： The invention generally relates to combining a plurality of flow streams. In various embodiments, a first channel transports a first laminar fluid flow, a second channel transports a second laminar fluid flow, and the first and second channels enter a merging region at an acute angle to one another along separate substantially parallel planes.
摘要翻译：本发明一般涉及组合多个流动流。在各种实施例中，第一通道输送第一层流体流，第二通道输送第二层流体流，并且第一和第二通道以分开的基本上平行的平面彼此成锐角进入锐角。

18. 发明授权

US5391269A Method of making an article comprising a silicon body 失效
标题翻译：制造包含硅体的制品的方法
公开(公告)号：US5391269A
公开(公告)日：1995-02-21
申请号：US84689
申请日：1993-06-29
申请人： Jason O. Fiering , Barry Miller , Joseph Shmulovich
发明人： Jason O. Fiering , Barry Miller , Joseph Shmulovich
IPC分类号： H01L21/306 , G02B6/36 , H01L21/3063 , B23H3/00
CPC分类号： H01L21/3063 , Y10T29/49169
摘要： We have found that etching of a body that comprises exposed Si as well as a Ti-comprising metal layer (e.g., a patterned Ti/Pt layer) in an amine-based anisotropic etchant for Si (e.g., 100.degree. C. EDP) frequently results in undesirable changes in the Ti-comprising metal layer. We have also found that the changes can be substantially reduced or eliminated by electrolytic means, namely, by making the metal layer the anode in an electrolytic cell that contains the etchant.
摘要翻译：我们已经发现，在基于胺的各向异性蚀刻剂（例如，100℃EDP）中经常蚀刻包括暴露的Si以及包含Ti的金属层（例如，图案化的Ti / Pt层）的主体导致含Ti的金属层的不期望的变化。我们还发现，通过电解方式，即通过在含有蚀刻剂的电解槽中使金属层成为阳极，可以显着地减少或消除这些变化。

19. 发明授权

US06572551B1 Imaging catheters for volumetric intraluminal ultrasound imaging 有权
标题翻译：成像导管体积管腔内超声成像
公开(公告)号：US06572551B1
公开(公告)日：2003-06-03
申请号：US09546721
申请日：2000-04-11
申请人： Stephen W. Smith , Edward D. Light , Jason O. Fiering
发明人： Stephen W. Smith , Edward D. Light , Jason O. Fiering
IPC分类号： A61B800
CPC分类号： A61B8/12 , A61B5/0422 , A61B8/0833 , A61B8/4488 , A61B90/36 , Y10S128/916
摘要： A real time three dimensional ultrasound imaging probe apparatus is configured to be placed inside a body. The apparatus comprises an elongated body having proximal and distal ends with an ultrasonic transducer phased array connected to and positioned on the distal end of the elongated body. The ultrasonic transducer phased array is positioned to emit and receive ultrasonic energy for volumetric forward scanning from the distal end of the elongated body. The ultrasonic transducer phased array includes a plurality of sites occupied by ultrasonic transducer elements. At least one ultrasonic transducer element is absent from at least one of the sites, thereby defining an interstitial site. A tool is positioned at the interstitial site. In particular, the tool can be a fiber optic lead, a suction tool, a guide wire, an electrophysiological electrode, or an ablation electrode. Related systems are also discussed.
摘要翻译：实时三维超声成像探针装置被配置为放置在体内。该装置包括细长体，其具有近端和远端，超声换能器相控阵列连接到并定位在细长体的远端上。超声波换能器相控阵列被定位成从细长体的远端发射和接收用于体积向前扫描的超声波能量。超声波换能器相控阵列包括由超声换能器元件占据的多个位置。至少一个站点不存在至少一个超声波换能器元件，从而限定了间隙位置。工具位于插页式广告位置。特别地，该工具可以是光纤引线，吸引工具，导丝，电生理电极或消融电极。还讨论了相关系统。

20. 发明授权

US09184496B2 Inductors having fluidic constructs that permit reconfiguration of the inductors 有权
标题翻译：具有允许重新配置电感器的流体结构的电感器
公开(公告)号：US09184496B2
公开(公告)日：2015-11-10
申请号：US13252695
申请日：2011-10-04
申请人： Amy E. Duwel , Jason O. Fiering , Douglas W. White , Brian R. Smith
发明人： Amy E. Duwel , Jason O. Fiering , Douglas W. White , Brian R. Smith
IPC分类号： H01Q1/00 , H01Q1/36 , H01Q3/01 , H01Q3/44
CPC分类号： H01Q1/364 , H01Q3/01 , H01Q3/44
摘要： In various embodiments, an inductance of an inductor is tuned by adjusting a position of a conductor and/or a magnetic material with respect to a conducting wire of the inductor, thereby changing the electro-magnetic characteristics of the conducting wire. The conductor and/or magnetic material can be disposed in a microfluidic channel and can be moved within the microfluidic channel using a suitable actuator mechanism.
摘要翻译：在各种实施例中，通过相对于电感器的导线调节导体和/或磁性材料的位置来调节电感器的电感，由此改变导线的电磁特性。导体和/或磁性材料可以设置在微流体通道中并且可以使用合适的致动器机构在微流体通道内移动。

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