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11. 发明授权

US08976003B2 Large-scale document authentication and identification system 有权
标题翻译：大型文件认证和识别系统
公开(公告)号：US08976003B2
公开(公告)日：2015-03-10
申请号：US12564993
申请日：2009-09-23
申请人： George E. Corbin , Anthony Grech , Thomas E. Murphy, Jr. , Mark Nelson , Kevin H. Peters
发明人： George E. Corbin , Anthony Grech , Thomas E. Murphy, Jr. , Mark Nelson , Kevin H. Peters
IPC分类号： G05B19/00 , G06F21/64
CPC分类号： G06F21/64
摘要： Computer-implemented methods, systems, and computer program products for document authentication and identification using a large-scale distributed system are provided. A method includes receiving a digitized document at a trusted system managed by a trusted third-party that is separate from a creator of content in the digitized document. The digitized document is compared to a set of markers to determine whether the digitized document includes one or more of the markers, and in response thereto, information associated with the one or more markers is extracted using a decoder on the trusted system according to encoding strategies. The method further includes generating a comparison registration identifier on the trusted system as a summary of the extracted information and the one or more markers, and comparing the comparison registration identifier with a stored registration identifier in an encoding history via the trusted system to authenticate and identify the received digitized document.
摘要翻译：提供了使用大规模分布式系统进行文档认证和识别的计算机实现的方法，系统和计算机程序产品。一种方法包括在由数字化文档中的内容的创建者分离的受信任的第三方管理的受信系统处接收数字化文档。将数字化文档与一组标记进行比较以确定数字化文档是否包括一个或多个标记，并且响应于此，根据编码策略，使用可信系统上的解码器提取与一个或多个标记相关联的信息。该方法还包括在可信系统上生成比较注册标识符作为提取的信息和一个或多个标记的摘要，并且通过可信系统将比较注册标识符与编码历史中存储的注册标识符进行比较，以验证和识别收到的数字化文件。

12. 发明授权

US08753313B2 Introducer handle notch design/concept 有权
标题翻译：介绍手柄槽设计/概念
公开(公告)号：US08753313B2
公开(公告)日：2014-06-17
申请号：US13555470
申请日：2012-07-23
申请人： Scott Kimmel , Nicholas Kampa , Mark Nelson , Blane Larson
发明人： Scott Kimmel , Nicholas Kampa , Mark Nelson , Blane Larson
IPC分类号： A61M5/178
CPC分类号： A61M25/0043 , A61B17/34 , A61M25/0097 , A61M25/0668 , A61M29/00
摘要： An improved splittable medical device introducer designed to introduce a medical device such as a lead or catheter, into a patient's vasculature without loss of blood or introduction of air is described. The introducer assembly is designed with a notch provided at the proximal end of the introducer housing. The notch, which may comprise a multitude of cross-sectional geometries, is designed to reduce the force required to separate the housing and the introducer sheath, thereby minimizing the possibility of unintentional dislodgement during separation. The notch also increases the repeatability and consistency of the amount of force required to separate the introducer housing and sheath.
摘要翻译：描述了一种改进的可分裂医疗装置导引器，其被设计成将诸如引线或导管的医疗装置引入病人的脉管系统中而不会损失血液或引入空气。导引器组件设计成具有设置在导引器壳体的近端处的凹口。可以包括多个横截面几何形状的凹口被设计成减小分离壳体和导引器鞘所需的力，从而最小化在分离期间意外移动的可能性。切口还增加了分离导引器壳体和护套所需的力的重复性和一致性。

13. 发明授权

US08576049B2 Document authentication and identification 有权
标题翻译：文件认证和识别
公开(公告)号：US08576049B2
公开(公告)日：2013-11-05
申请号：US12564982
申请日：2009-09-23
申请人： George E. Corbin , Anthony Grech , Thomas E. Murphy, Jr. , Mark Nelson , Kevin H. Peters
发明人： George E. Corbin , Anthony Grech , Thomas E. Murphy, Jr. , Mark Nelson , Kevin H. Peters
IPC分类号： H04L9/32 , G06F17/00 , G06F19/00 , G06F7/00 , G06F7/04 , G06K13/00 , H04Q9/00 , G05B19/00 , G05B23/00 , G08B29/00
CPC分类号： H04N1/32144 , G06F21/64 , H04N2201/3233 , H04N2201/327 , H04N2201/3277
摘要： Computer-implemented methods, systems, and computer program products for document authentication and identification using encoding and decoding are provided. A method includes receiving a digitized document and comparing the digitized document to a set of markers to determine whether the digitized document is an encoded document with one or more characters replaced. In response to determining that the digitized document is encoded, information is extracted from the set of markers using a decoder according to an encoding strategy. The extracted information and the set of markers are compared with data stored in encoding history to authenticate and identify the received digitized document. Markers in the encoded document may be hidden in plain sight, such that the encoding is not readily apparent to a casual observer.
摘要翻译：提供了使用编码和解码的用于文档认证和识别的计算机实现的方法，系统和计算机程序产品。一种方法包括接收数字化文档并将数字化文档与一组标记进行比较，以确定数字化文档是否是被替换了一个或多个字符的编码文档。响应于确定数字化文档被编码，使用解码器根据编码策略从标记集合中提取信息。将提取的信息和标记集合与存储在编码历史中的数据进行比较，以验证和识别所接收的数字化文档。编码文档中的标记可能被隐藏在明显的视觉中，使得编码对于临时观察者来说不是显而易见的。

14. 发明授权

US08308659B2 Bi-directional sheath deflection mechanism 有权
标题翻译：双向鞘偏转机制
公开(公告)号：US08308659B2
公开(公告)日：2012-11-13
申请号：US12463570
申请日：2009-05-11
申请人： Grant A. Scheibe , Mark Nelson
发明人： Grant A. Scheibe , Mark Nelson
IPC分类号： A61B5/00 , A61M25/00 , A61M31/00 , A61M37/00
CPC分类号： A61M25/0136
摘要： A deflectable sheath for use in medical procedures in the vasculature is described. The sheath includes a handle supporting the sheath. Two pull wires run along opposite sides of the sheath to anchors at the deflectable distal end. The handle includes a rotatable member that moves a threaded member including wire guide in a back and forth translation. As the movement occurs, force is applied to either one or the other of the pull wires to cause deflection of distal end of the sheath in either and upwardly or a downwardly direction with respect to the longitudinal axis of the sheath.
摘要翻译：描述了用于脉管系统中的医疗程序的可偏转护套。鞘包括支撑鞘的手柄。两条牵引线沿护套的相对侧延伸，以锚定在可偏转的远端。手柄包括可旋转构件，该可旋转构件使包括导线器的螺纹构件在前后平移中移动。当运动发生时，力被施加到牵引线中的一个或另一个以引起护套的远端相对于护套的纵向轴线向上或向下的方向偏转。

15. 发明申请

US20100269221A1 Novel Bacillus Thuringiensis Gene with Lepidopteran Activity 有权
公开(公告)号：US20100269221A1
公开(公告)日：2010-10-21
申请号：US12436171
申请日：2009-05-06
申请人： Andre R. Abad , Hua Dong , Susan B. Lo , Mark Nelson , Xiaomei Shi , Clement W.K. Waine , Takashi Yamamoto
发明人： Andre R. Abad , Hua Dong , Susan B. Lo , Mark Nelson , Xiaomei Shi , Clement W.K. Waine , Takashi Yamamoto
IPC分类号： A01H1/00 , A01H5/00 , C12N15/82 , C07H21/04 , C12N1/21 , C12N5/10 , C12N15/63 , C12N15/79 , C07K14/00 , A01N61/00 , C12P21/02 , A01P7/04
CPC分类号： C12N15/8286 , C07K14/32 , Y02A40/162
摘要： The invention provides nucleic acids, and variants and fragments thereof, obtained from strains of Bacillus thuringiensis encoding polypeptides having pesticidal activity against insect pests, including Lepidoptera. Particular embodiments of the invention provide isolated nucleic acids encoding pesticidal proteins, pesticidal compositions, DNA constructs, and transformed microorganisms and plants comprising a nucleic acid of the embodiments. These compositions find use in methods for controlling pests, especially plant pests.

16. 发明申请

US20100231606A1 INFERRING DIAGRAM STRUCTURE THROUGH IMPLICIT SHAPE RELATIONSHIPS 有权
标题翻译：通过隐含的形状关系传达图形结构
公开(公告)号：US20100231606A1
公开(公告)日：2010-09-16
申请号：US12404404
申请日：2009-03-16
申请人： Mark Nelson , Michael Woolf , Heidi Munson , David Bradlee, JR. , Evan Moran
发明人： Mark Nelson , Michael Woolf , Heidi Munson , David Bradlee, JR. , Evan Moran
IPC分类号： G09G5/00 , G06F9/44
CPC分类号： G06T3/20 , G06F3/03543 , G06F3/04817 , G06F3/0482 , G06F3/04842 , G06F3/04845 , G06T3/40 , G06T11/206
摘要： Information in a diagram is logically structured using lists, containers, and callouts without requiring the diagram author to explicitly define a structure or map any diagram contents to a structure. Logical relationships are inferred based on actions associated with shapes, groupings, and attributes of shapes/groupings taken by the author. Feedback mechanisms are provided to communicate an underlying structure to the author. Intelligent behaviors are enabled to expose manipulation of diagrams based on their logical structure.
摘要翻译：图中的信息使用列表，容器和标注进行逻辑结构，而不需要图表作者明确定义结构或将任何图表内容映射到结构。逻辑关系是基于与作者采取的形状，分组和形状/分组的属性相关联的动作来推断的。提供反馈机制以向作者传达基础结构。智能行为能够根据逻辑结构公开对图表的操纵。

17. 发明申请

US20090265818A1 COMPOSITIONS AND METHODS FOR THE SUPPRESSION OF TARGET POLYNUCLEOTIDES FROM LEPIDOPTERA 有权
标题翻译：用于抑制来自LEPIDOPTERA的目标多核苷酸的组合物和方法
公开(公告)号：US20090265818A1
公开(公告)日：2009-10-22
申请号：US12351267
申请日：2009-01-09
申请人： Rafael Herrmann , Michael Lassner , Albert L. Lu , Mark Nelson , James K. Presnail , Janet A. Rice
发明人： Rafael Herrmann , Michael Lassner , Albert L. Lu , Mark Nelson , James K. Presnail , Janet A. Rice
IPC分类号： A01H5/00 , C12N5/04 , A01N43/04 , A01P7/04
CPC分类号： C12N15/8286 , A01N65/20 , A01N65/44 , C12N15/113 , C12N2310/11 , C12N2310/14 , C12N2310/531 , C12N2320/32 , Y02A40/162
摘要： Methods and compositions are provided which employ a silencing element that, when ingested by a pest, such as a pest from the Lepidoptera order, they are capable of decreasing the expression of a target sequence in the pest. In specific embodiments, the decrease in expression of the target sequence controls the pest and thereby the methods and compositions are capable of limiting damage to a plant. The present invention provides target polynucleotides encoding polypeptides from specific protein families and various target polynucleotides set forth in SEQ ID NOS: 1, 2, 3, 4, 5, 6, 7, 8, 9, 10, 11, 12, 13, 14, 15, 16, 17, 18, 19, 20, 21, 22, 23, 24, 25, 26, 27, 28, 29, 30, 31, 32, 33, 34, 35, 36, 37, 38, 39, 40, 41, 42, 43, 44, 45, 46, 47, 48, 49, or 50 or active variants and fragments thereof, wherein a decrease in expression of one or more the sequences in the target pest controls the pest (i.e., has insecticidal activity). Further provided are silencing elements which when ingested by the pest decrease the level of the target polypeptide and thereby control the pest. In specific embodiment, the pest is Spodoptera frugiperda. Plants, plant part, bacteria and other host cells comprising the silencing elements or an active variant or fragment thereof of the invention are also provided.
摘要翻译：提供了使用沉积元件的方法和组合物，当沉积元件在被害虫如来自鳞翅目序列的害虫中摄取时，它们能够降低害虫中靶序列的表达。在具体实施方案中，靶序列的表达降低控制有害生物，因此方法和组合物能够限制对植物的损害。本发明提供编码来自特定蛋白质家族的多肽的多核苷酸和SEQ ID NO：1,2,3,4,5,6,7,8,9,10,11,12,13,14中所示的各种靶多核苷酸的靶多核苷酸，15，16，17，18，19，20，21，22，23，24，25，26，27，28，29，30，31，32，33，34，35，36，37，38，39 ，40,41,42,43,44,45,46,47,48,49或50个或其活性变体和片段，其中目标害虫中一个或多个序列的表达降低控制害虫（即，具有杀虫活性）。进一步提供的是沉积元件，当受害虫摄入时，降低靶多肽的水平，从而控制害虫。在具体实施方案中，害虫是草地夜蛾（Spodoptera frugiperda）。还提供了包含本发明的沉默元件或其活性变体或片段的植物，植物部分，细菌和其它宿主细胞。

18. 发明申请

US20070167415A1 Tetracycline compounds for treatment of cryptosporidium parvum related disorders 失效
公开(公告)号：US20070167415A1
公开(公告)日：2007-07-19
申请号：US11728346
申请日：2007-03-26
申请人： Stuart Levy , Mark Nelson
发明人： Stuart Levy , Mark Nelson
IPC分类号： A61K31/65
CPC分类号： A61K31/65 , C07C237/26 , C07C2601/10 , Y02A50/488
摘要： Methods and compositions for treating Cryptosporidium parvum related disorders in a mammal are discussed. Several novel tetracycline compounds useful for treating Cryptosporidium parvum related disorders are also included.

19. 发明申请

US20070155349A1 Systems and methods for selectively controlling electrical outlets using power profiling 有权
标题翻译：使用功率分析选择性地控制电源插座的系统和方法
公开(公告)号：US20070155349A1
公开(公告)日：2007-07-05
申请号：US11321705
申请日：2005-12-29
申请人： Mark Nelson , W. Eastham , James Simister
发明人： Mark Nelson , W. Eastham , James Simister
IPC分类号： H04B1/034
CPC分类号： H04L12/00 , H02J13/0013 , Y02B70/3266 , Y02B90/2607 , Y04S20/242 , Y04S40/12
摘要： A system for selectively controlling electrical outlets using power profiling is disclosed. There is a plurality of electrical outlets that each comprises a power socket capable of receiving a plug, an outlet identification and a switch that when in a first position no power is available at the power socket, and when the switch is in a second position power is available at the power socket. A controller is in electronic communication with the plurality of electrical outlets. The controller includes a processor and memory in electronic communication with the processor. The controller also includes power profiles and operates to receive data from an electrical outlet of the plurality of electrical outlets. A device or class of device is identified based on the received data. A power profile is identified based on the received data. Action is taken based on the power profile.
摘要翻译：公开了一种用于使用功率轮廓来选择性地控制电源插座的系统。存在多个电插座，每个电插座包括能够接收插头的电源插座，插座标识和开关，当处于第一位置时，电源插座处的电源不可用，并且当开关处于第二位置时，电源在电源插座上可用。控制器与多个电插座电子通信。控制器包括处理器和与处理器电子通信的存储器。控制器还包括电源配置文件并且操作以从多个电插座的电源插座接收数据。基于接收到的数据来识别设备或类别的设备。基于接收到的数据识别功率分布。基于电源配置文件执行操作。

20. 发明申请

US20070072834A1 13-Substituted methacycline compounds 审中-公开
标题翻译： 13-取代的甲基环霉素化合物
公开(公告)号：US20070072834A1
公开(公告)日：2007-03-29
申请号：US11397445
申请日：2006-04-04
申请人： Mark Nelson , Beena Bhatia , Laura McIntyre , Glen Rennie
发明人： Mark Nelson , Beena Bhatia , Laura McIntyre , Glen Rennie
IPC分类号： A61K31/65 , C07C237/26
CPC分类号： C07C231/12 , C07C237/26
摘要： 13-substituted methacycline compounds, methods of treating tetracycline responsive states, and pharmaceutical compositions containing the 13-substituted methacycline compounds are described.
摘要翻译：描述了13-取代的甲基环霉素化合物，治疗四环素应答状态的方法和含有13-取代的甲基环霉素化合物的药物组合物。

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