专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明申请

WO2006008537A3 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2006008537A3
公开(公告)日：2007-01-18
申请号：PCT/GB2005002874
申请日：2005-07-21
申请人： MICROMASS LTD , BATEMAN ROBERT HAROLD , BROWN JEFFERY , GREEN MARTIN
发明人： BATEMAN ROBERT HAROLD , BROWN JEFFERY , GREEN MARTIN
IPC分类号： H01J49/04 , H01J49/40 , H01J49/42
CPC分类号： H01J49/062 , H01J49/027 , H01J49/422 , H01J49/4245
摘要： A mass spectrometer is disclosed comprising a segmented linear ion guide or ion trap. Ions are confined radially within the ion guide or ion trap by the application of an AC or RF voltage to the electrodes forming the ion guide or ion trap. A quadratic DC potential is applied along the axial length of the ion guide or ion trap in order to cause trapped ions to perform simple harmonic motion within the ion guide or ion trap. The frequency of the oscillations of the ions is detected using one or more inductive detectors. The mass to charge ratio of the ions can then be determined from the determined frequency of oscillations.
摘要翻译：公开了一种质谱仪，其包括分段线性离子导向器或离子阱。通过对形成离子导向器或离子阱的电极施加AC或RF电压，离子导向器或离子阱中的离子被径向限制。沿着离子导向器或离子阱的轴向长度施加二次直流电位，以使被捕获的离子在离子导向器或离子阱内进行简单的谐波运动。使用一个或多个感应检测器检测离子振荡的频率。然后可以从确定的振荡频率确定离子的质荷比。

12. 发明申请

WO2005098899A3 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2005098899A3
公开(公告)日：2006-12-28
申请号：PCT/GB2005001290
申请日：2005-04-04
申请人： MICROMASS LTD , GREEN MARTIN , WILDGOOSE JASON LEE , PRINGLE STEVEN DEREK , GILES KEVIN
发明人： GREEN MARTIN , WILDGOOSE JASON LEE , PRINGLE STEVEN DEREK , GILES KEVIN
IPC分类号： H01J49/04 , G01T1/36 , H01J49/06 , H01J49/16 , H01J49/26 , H01J49/40
CPC分类号： H01J49/06 , Y10T436/24
摘要： A mass spectrometer is disclosed comprising an ion beam attenuator which attenuates an ion beam repeatedly switching between a zero transmission mode of operation during a time period ?T1 and a non-zero transmission mode of operation during a time period ?T 2 . The degree of attenuation of the ion beam can be varied by varying the mark space ratio ?T 2 /?T 1 . The ion beam attenuator may release ions in packets or pulses but the packets or pulses of ions may be converted into a continuous ion beam by a relatively high pressure ion guide or gas collision cell arranged downstream of the ion beam attenuator.
摘要翻译：公开了一种质谱仪，其包括离子束衰减器，该离子束衰减器在时间段ΔT1期间衰减离子束在时间段ΔT1内的零传输模式和非零传输模式之间重复切换， / SUB>。离子束的衰减程度可以通过改变标记空间比ΔT2 /βT 1 1来改变。离子束衰减器可以以分组或脉冲的形式释放离子，但是离子束或脉冲可以通过布置在离子束衰减器下游的相对高压的离子导向器或气体碰撞元件转换为连续的离子束。

13. 发明申请

WO2005104178A3 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2005104178A3
公开(公告)日：2006-10-12
申请号：PCT/GB2005001585
申请日：2005-04-26
申请人： MICROMASS LTD , GREEN MARTIN , BATEMAN ROBERT HAROLD
发明人： GREEN MARTIN , BATEMAN ROBERT HAROLD
IPC分类号： H01J49/02 , H01J9/00 , H01J31/00 , H01J37/00 , H01J43/24 , H01J49/10 , H04N5/00
CPC分类号： H01J43/246 , H01J49/025
摘要： An ion detector for a mass spectrometer is provided wherein a mask (10) is provided between a first microchannel plate (2a) and a second microchannel plate (2b). The mask (10) prevents ion arrival events causing a cloud of secondary electrons to be from the second microchannel plate (2b) which would illuminate two collection anodes (5,6) at substantially the same time. The mask (10) also prevents electron clouds emitted which would otherwise vary significantly in intensity.
摘要翻译：提供了一种用于质谱仪的离子检测器，其中掩模（10）设置在第一微通道板（2a）和第二微通道板（2b）之间。掩模（10）防止导致二次电子云的离子到达事件来自第二微通道板（2b），其将基本上同时照射两个收集阳极（5,6）。掩模（10）还防止了发射的电子云，否则其强度将显着变化。

14. 发明申请

WO2008102155A3 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2008102155A3
公开(公告)日：2009-06-25
申请号：PCT/GB2008000617
申请日：2008-02-21
申请人： MICROMASS LTD , BATEMAN ROBERT HAROLD , GREEN MARTIN , WILDGOOSE JASON LEE
发明人： BATEMAN ROBERT HAROLD , GREEN MARTIN , WILDGOOSE JASON LEE
IPC分类号： H01J49/42
CPC分类号： H01J49/0095 , H01J49/423 , H01J49/424
摘要： A mass spectrometer is disclosed comprising a 2D or 3D ion trap. The 2D ion trap comprises a quadrupole rod set ion trap wherein a slot is provided in each of the rods 1 to allow ions to be ejected radially from the ion trap. The 3D ion trap comprises a central ring electrode which is radially segmented and wherein a slot is provided in each radial segment to allow ions to be ejected radially from the ion trap. Ions having different mass to charge ratios and/or opposite polarities may be simultaneously ejected from the ion trap via different exit pathways.
摘要翻译：公开了包括2D或3D离子阱的质谱仪。 2D离子阱包括四极棒组离子阱，其中在每个棒1中设置槽，以允许离子从离子阱径向喷射。 3D离子阱包括径向分段的中心环电极，并且其中在每个径向段中设置狭槽以允许离子从离子阱径向喷射。具有不同质荷比和/或相反极性的离子可以通过不同的出口通道从离子阱同时喷出。

15. 发明申请

WO2008071993A3 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2008071993A3
公开(公告)日：2009-04-02
申请号：PCT/GB2007004820
申请日：2007-12-14
申请人： MICROMASS LTD , KENNY DANIEL JAMES , WILDGOOSE JASON LEE , GREEN MARTIN
发明人： KENNY DANIEL JAMES , WILDGOOSE JASON LEE , GREEN MARTIN
IPC分类号： H01J49/40
CPC分类号： H01J49/401
摘要： A mass spectrometer is disclosed comprising an orthogonal acceleration Time of Flight mass analyser. A pulse or packet of ions is released either from an ion trap (7) or alternatively from a travelling wave ion guide arranged upstream of an orthogonal acceleration electrode (2) which forms part of the Time of Flight mass analyser. Ions in the pulse or packet of ions which is released become temporally dispersed and the orthogonal acceleration electrode (2) is energised multiple times prior the release of a subsequent pulse or packet of ions.
摘要翻译：公开了一种质谱仪，其包括正交加速时间飞行质量分析器。从离子阱（7）或替代地从布置在作为飞行时间质量分析器的一部分的正交加速电极（2）的上游的行波离子导向器释放脉冲或包离子。释放的脉冲或离子束中的离子变得暂时分散，并且在随后的脉冲或包离子的释放之前，正交加速电极（2）被多次通电。

16. 发明申请

WO2008068515A3 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2008068515A3
公开(公告)日：2009-04-02
申请号：PCT/GB2007004732
申请日：2007-12-10
申请人： MICROMASS LTD , GREEN MARTIN , WILDGOOSE JASON LEE
发明人： GREEN MARTIN , WILDGOOSE JASON LEE
IPC分类号： H01J49/40 , H01J49/06
CPC分类号： H01J49/40 , H01J49/004 , H01J49/005 , H01J49/062 , H01J49/063 , H01J49/065 , H01J49/066
摘要： A mass spectrometer is disclosed comprising a time of flight mass analyser (7). The time of flight mass analyser (7) comprises an ion guide comprising a plurality of electrodes (1) which are interconnected by. a series of resistors (2) forming a potential divider. Ions are confined radially within the ion guide by the application of a two-phase RF voltage to the electrodes (1). A single phase additional RF voltage is applied across the potential divider so that an inhomogeneous pseudo-potential force is maintained along the length of the ion guide.
摘要翻译：公开了一种包括飞行时间质量分析器（7）的质谱仪。飞行时间质量分析器（7）包括离子导向器，其包括多个电极（1），所述多个电极通过相互连接。形成分压器的一系列电阻器（2）。通过向电极（1）施加两相RF电压，离子在径向上被限制在离子导向器内。在分压器上施加单相附加RF电压，使得沿着离子导向器的长度保持不均匀的伪势力。

17. 发明申请

WO2008142418A2 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2008142418A2
公开(公告)日：2008-11-27
申请号：PCT/GB2008001756
申请日：2008-05-22
申请人： MICROMASS LTD , GREEN MARTIN , PRINGLE STEVEN DEREK , WILDGOOSE JASON LEE
发明人： GREEN MARTIN , PRINGLE STEVEN DEREK , WILDGOOSE JASON LEE
CPC分类号： H01J49/0036 , H01J49/40
摘要： A mass spectrometer is disclosed wherein an ion signal is split into a first and second signal. The first and second signals are multiplied by different gains and are digitised. Arrival time and intensity pairs are calculated for both digitised signals and the resulting time and intensity pairs are combined to form a high dynamic range spectrum. The spectrum is then combined with other corresponding spectra to form a summed spectrum.
摘要翻译：公开了一种质谱仪，其中离子信号被分成第一和第二信号。第一和第二信号乘以不同的增益并被数字化。对于两个数字化信号计算到达时间和强度对，并且将所得到的时间和强度对组合以形成高动态范围谱。然后将光谱与其他对应的光谱组合以形成相加光谱。

18. 发明申请

WO2008117040A2 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2008117040A2
公开(公告)日：2008-10-02
申请号：PCT/GB2008001028
申请日：2008-03-26
申请人： MICROMASS LTD , GREEN MARTIN , WILDGOOSE JASON LEE , BROWN JEFFERY MARK
发明人： GREEN MARTIN , WILDGOOSE JASON LEE , BROWN JEFFERY MARK
IPC分类号： H01J49/06
CPC分类号： H01J49/0481 , H01J49/0072 , H01J49/065 , H01J49/40 , Y10T436/24
摘要： A mass spectrometer is disclosed comprising an Electron Transfer Dissociation cell (1). Positive analyte ions are fragmented into fragment ions upon colliding with singly charged negative reagent ions with the cell (1). The cell comprises a plurality of ring electrodes (1) which form a spherical trapping volume. Ions experience negligible RF heating over the majority. of the trapping volume which enables the kinetic energy of the analyte and reagent ions to be reduced to just above thermal temperatures. An Electron Transfer Dissociation cell (1) having an enhanced sensitivity is thereby provided. Fragment ions created within the cell (1) may be cooled and may be transmitted onwardly to an orthogonal acceleration Time of Flight mass analyser enabling a significant improvement in the resolution of the mass analyser to be obtained.
摘要翻译：公开了包含电子转移离解电池（1）的质谱仪。当与单体电荷的负试剂离子碰撞时，阳性分析物离子被碎裂成碎片离子（1）。电池包括形成球形捕获体积的多个环形电极（1）。在多数情况下，离子经验可以忽略不计。的捕获体积，其使分析物和试剂离子的动能降低到恰好高于热温度。由此提供了具有增强的灵敏度的电子转移解离单元（1）。在细胞（1）内产生的片段离子可以被冷却并且可以向内传播到正交加速时间飞行质量分析仪，使得可以获得质量分析仪的分辨率的显着提高。

19. 发明申请

WO2007125354A2 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2007125354A2
公开(公告)日：2007-11-08
申请号：PCT/GB2007001589
申请日：2007-04-30
申请人： MICROMASS LTD , GREEN MARTIN , WILDGOOSE JASON LEE , PRINGLE STEVEN DEREK , KENNY DANIEL JAMES
发明人： GREEN MARTIN , WILDGOOSE JASON LEE , PRINGLE STEVEN DEREK , KENNY DANIEL JAMES
CPC分类号： H01J49/4235 , H01J49/065
摘要： An ion guide or mass analyser (2) is disclosed comprising a plurality of electrodes (2a) having apertures through which ions are transmitted in use. A pseudo-potential barrier is created at the exit of the ion guide or mass analyser (2). The amplitude or depth of the pseudo-potential barrier is inversely proportional to the mass to charge ratio of an ion. One or more transient DC voltages (4) are applied to the electrodes (2a) of the ion guide or mass analyser (2) in order to urge ions along the length of the ion guides or mass analyser (2). The amplitude of the transient DC voltage (4) applied to the electrode (2a) may be increased with time so that ions are caused to be emitted from the ion guide or mass analyser (2) in reverse order of their mass to charge ratio.
摘要翻译：公开了一种离子导向器或质量分析器（2），其包括具有孔的多个电极（2a），在使用中通过该孔具有离子。在离子导向器或质量分析器（2）的出口处产生伪势垒。伪势垒的幅度或深度与离子的质荷比成反比。一个或多个瞬态DC电压（4）被施加到离子导向器或质量分析器（2）的电极（2a），以促使沿着离子导向器或质量分析器（2）的长度的离子。施加到电极（2a）的瞬态直流电压（4）的振幅可以随时间增加，使得离子以其质荷比相反的顺序从离子导向器或质量分析器（2）发射。

20. 发明申请

WO2006090138A2 MASS SPECTROMETER 审中-公开
标题翻译：质谱仪
公开(公告)号：WO2006090138A2
公开(公告)日：2006-08-31
申请号：PCT/GB2006000613
申请日：2006-02-22
申请人： MICROMASS LTD , GREEN MARTIN , WILDGOOSE JASON LEE , GORENSTEIN MARC V
发明人： GREEN MARTIN , WILDGOOSE JASON LEE , GORENSTEIN MARC V
IPC分类号： H01J49/40
CPC分类号： H01J49/025 , H01J49/0036 , H01J49/40
摘要： A method of mass spectrometry is disclosed wherein distortions in a mass spectrum are corrected for by determining or estimating the number of ions Q i which arrived in an i th time bin, wherein: Formula (I) and wherein q i is the actual total number of ion arrival events recorded in the i th time bin and x is an integer corresponding to the number of time bins which correspond with an estimated deadtime period.
摘要翻译：公开了一种质谱法，其中通过确定或估计到达第i个时间仓的离子数Q i校正质谱中的失真，其中：式（I），其中q i i i是在第i个时间仓中记录的离子到达事件的实际总数，x是与时间数相对应的整数与预计的死时间相对应的箱子。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式