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11. 发明申请

US20100278627A1 CASSETTE AND EMBEDDING ASSEMBLY FOR HANDLING AND HOLDING TISSUE SAMPLES DURING PROCESSING, EMBEDDING AND MICROTOME PROCEDURES, STAGING DEVICES THEREFOR, AND METHODS THEREFOR 有权
标题翻译：用于处理，嵌入和微阵列程序的处理和保存组织样本的CASSETTE和嵌入式组件，其分类设备及其方法
公开(公告)号：US20100278627A1
公开(公告)日：2010-11-04
申请号：US12836102
申请日：2010-07-14
申请人： Warren P. Williamson, IV , Craig B. Berky , Stephen P. Whitlatch , Thomas J. Ward
发明人： Warren P. Williamson, IV , Craig B. Berky , Stephen P. Whitlatch , Thomas J. Ward
IPC分类号： C12M1/00 , B25J1/00
CPC分类号： G01N1/36 , B01L3/508 , B01L9/52 , B01L2300/043 , G01N2001/315 , G01N2001/366 , Y10T436/25
摘要： The disclosure relates to a cassette, frame and mold for holding a tissue sample during an embedding and mircotoming process, and related methods. The cassette is sectionable in a microtome and includes a body with a bottom wall and a plurality of side walls. First and second side walls are generally V-shaped to present an apex of the “V” to the microtome blade. A lid of the cassette is stiffer than the bottom wall of the cassette to assist with positioning the tissue sample. The side walls of the cassette are perforated so as to significantly reduce the amount of cassette material that must be cut by the microtome blade. In one embodiment, to additionally reduce blade wear the ribs on one side wall are offset lengthwise relative to the ribs on an opposite side wall. An upper flange of the cassette includes depressions configured to register with detents in the frame.
摘要翻译：本公开涉及一种用于在嵌入和微型切割过程期间保持组织样本的盒，框架和模具及相关方法。盒子可在切片机中切片，并且包括具有底壁和多个侧壁的主体。第一侧壁和第二侧壁通常为V形以呈现与切片机叶片“V”的顶点。盒的盖比盒的底壁更硬，以帮助定位组织样品。盒的侧壁是穿孔的，以便显着减少必须由切片机刀片切割的盒材料的量。在一个实施例中，为了额外地减少刀片磨损，一个侧壁上的肋相对于相对侧壁上的肋纵向偏移。盒的上凸缘包括配置成与框架中的棘爪对准的凹陷。

12. 发明授权

US07776274B2 Cassette and embedding assembly for handling and holding tissue samples during processing, embedding and microtome procedures, staging devices therefore, and methods therefor 有权
标题翻译：因此，在处理，嵌入和切片机程序期间处理和保持组织样本的盒式和嵌入组件，因此分级装置及其方法
公开(公告)号：US07776274B2
公开(公告)日：2010-08-17
申请号：US11072119
申请日：2005-03-04
申请人： Warren P. Williamson, IV , Craig B. Berky , Stephen P. Whitlatch , Thomas J. Ward
发明人： Warren P. Williamson, IV , Craig B. Berky , Stephen P. Whitlatch , Thomas J. Ward
IPC分类号： B01L9/00
CPC分类号： G01N1/36 , B01L3/508 , B01L9/52 , B01L2300/043 , G01N2001/315 , G01N2001/366 , Y10T436/25
摘要： The disclosure relates to a cassette, frame and mold for holding a tissue sample during an embedding and mircotoming process, and related methods. The cassette is sectionable in a microtome and includes a body with a bottom wall and a plurality of side walls. First and second side walls are generally V-shaped to present an apex of the “V” to the microtome blade. A lid of the cassette is stiffer than the bottom wall of the cassette to assist with positioning the tissue sample. The side walls of the cassette are perforated so as to significantly reduce the amount of cassette material that must be cut by the microtome blade. In one embodiment, to additionally reduce blade wear the ribs on one side wall are offset lengthwise relative to the ribs on an opposite side wall. An upper flange of the cassette includes depressions configured to register with detents in the frame.
摘要翻译：本公开涉及一种用于在嵌入和微型切割过程期间保持组织样本的盒，框架和模具及相关方法。盒子可在切片机中切片，并且包括具有底壁和多个侧壁的主体。第一侧壁和第二侧壁通常为V形以呈现与切片机叶片“V”的顶点。盒的盖比盒的底壁更硬，以帮助定位组织样品。盒的侧壁是穿孔的，以便显着减少必须由切片机刀片切割的盒材料的量。在一个实施例中，为了额外地减少刀片磨损，一个侧壁上的肋相对于相对侧壁上的肋纵向偏移。盒的上凸缘包括配置成与框架中的棘爪对准的凹陷。

13. 发明授权

US07497865B2 Method and apparatus for performing anastomosis with eversion of tissue edges and joining of exposed intima of the everted tissue 失效
标题翻译：用于通过外翻组织边缘进行吻合的方法和装置，以及接合外露组织的暴露内膜
公开(公告)号：US07497865B2
公开(公告)日：2009-03-03
申请号：US10855604
申请日：2004-05-26
申请人： Geoffrey H. Willis , Thomas A. Kramer , Paul A. Spence , George T. Christakis , Timothy J. McCoy , John W. Davis , Bradley D. Blackwood , Peter Callas , Michael Francis Wei , Jonathan L. Podmore , Andrew Knight , Thomas J. Ward , Warren P. Williamson, IV
发明人： Geoffrey H. Willis , Thomas A. Kramer , Paul A. Spence , George T. Christakis , Timothy J. McCoy , John W. Davis , Bradley D. Blackwood , Peter Callas , Michael Francis Wei , Jonathan L. Podmore , Andrew Knight , Thomas J. Ward , Warren P. Williamson, IV
IPC分类号： A61B17/08 , A61B17/10 , A61B17/04
CPC分类号： A61B17/1152 , A61B17/11 , A61B17/115 , A61B2017/1107 , A61B2017/1132 , A61B2017/1135 , A61B2017/1139
摘要： A ring for use in anastomosis. Preferably, the ring is integrally formed from metal, and includes a ring portion and tines and docking members that extend from the ring portion. The ring portion and tines are malleable, and preferably also the docking members are malleable. The ring portion and tines are malleable in the sense that once deformed from a first shape into a second shape, they will not relax back into the first shape from the second. To install the ring in a vessel with the ring portion extending around an incision or other orifice, the tines pierce the tissue around the orifice and are curled against an anvil. The action of curling the tines inverts the tissue near the orifice edges to expose the inside surface of the vessel or organ. Other aspects of the invention are a method and apparatus for installing an anastomosis ring in an incision or other orifice in a vessel or other organ, a method and apparatus for precisely aligning two anastomosis rings (each installed in an incision or other orifice of a different organ) and fastening the aligned rings together. The clips can be crimped onto the aligned rings, or they can be spring clips which are sprung onto the aligned rings to clamp the rings together by spring force. Also within the scope of the invention are crimping and spring clips for use in listening together two aligned anastomosis rings. In other embodiments, the invention is a method for performing an anastomosis by installing an anastomosis ring in an orifice in an organ, installing another anastomosis ring in an orifice in another organ, precisely aligning the two installed anastomosis rings, and fastening the aligned rings together.
摘要翻译：用于吻合的戒指。优选地，环由金属一体地形成，并且包括从环部延伸的环部分和尖齿和对接构件。环形部分和尖齿是可延展的，并且优选的是对接部件是可延展的。环形部分和尖齿在从第一形状变形成第二形状的意义上是可延展的，它们将不会从第二形状放松回第一形状。为了将环安装在具有围绕切口或其他孔口延伸的环部分的容器中，齿刺穿孔周围的组织并且卷绕在砧座上。卷曲尖齿的作用使孔边缘附近的组织反转以暴露血管或器官的内表面。本发明的其它方面是用于将吻合环安装在容器或其他器官中的切口或其它孔中的方法和装置，用于精确地对准两个吻合环（每个安装在切口或不同的其他孔中的其他孔中的方法和装置）器官）并将对准的环固定在一起。夹子可以压接在对准的环上，或者它们可以是弹簧夹，弹簧夹被弹簧上对准的环，以通过弹簧力将环夹在一起。也在本发明的范围内的是压接和弹簧夹，用于一起收听两个对准的吻合环。在其他实施例中，本发明是一种通过在器官中的孔中安装吻合环来进行吻合的方法，在另一个器官的孔中安装另一个吻合环，精确对准两个安装的吻合环，并将对准的环固定在一起。

14. 发明申请

US20110165615A1 APPARATUS AND METHODS FOR AUTOMATED HANDLING AND EMBEDDING OF TISSUE SAMPLES 有权
标题翻译：装置和组织样品的自动处理和嵌入方法
公开(公告)号：US20110165615A1
公开(公告)日：2011-07-07
申请号：US13047053
申请日：2011-03-14
申请人： Douglas P. Allen , Dominic P. DiNovo , George A. Keller , Rebeccah P. Quam , Thomas J. Ward , Warren P. Williamson, IV
发明人： Douglas P. Allen , Dominic P. DiNovo , George A. Keller , Rebeccah P. Quam , Thomas J. Ward , Warren P. Williamson, IV
IPC分类号： G01N1/30 , C12M1/34
CPC分类号： G01N1/36 , G01N35/00732 , G01N2001/366 , Y10T436/2525 , Y10T436/2575
摘要： An automated machine for handling and embedding tissue samples contained on microtome sectionable supports. The machine includes an input member configured to hold a plurality of the microtome sectionable supports prior to a tissue embedding operation. An output member is configured to hold a plurality of the microtome sectionable supports after the tissue embedding operation. A cooling unit is configured to hold at least one of the microtome sectionable supports during the tissue embedding operation. A motorized carrier assembly is mounted for movement and configured to hold at least one of the microtome sectionable supports. The carrier assembly moves the support from the input member to the cooling unit and, finally, to the output member. A dispensing device dispenses an embedding material onto the microtome sectionable support and at least one tissue sample carried by the microtome sectionable support during the embedding operation.
摘要翻译：一种用于处理和嵌入包含在切片机可切片支架上的组织样本的自动化机器。该机器包括一个输入构件，构造成在组织嵌入操作之前保持多个切片机可切割支架。输出构件被配置为在组织嵌入操作之后保持多个切片机可切割支撑件。冷却单元构造成在组织嵌入操作期间保持切片机可分段支撑件中的至少一个。安装电动载体组件用于移动并且构造成保持切片机可分段支撑件中的至少一个。托架组件将支撑件从输入构件移动到冷却单元，最后移动到输出构件。分配装置在嵌入操作期间将嵌入材料分配到切片机可切片支撑件和由切片机可切割支撑件携带的至少一个组织样本。

15. 发明授权

US08034292B2 Apparatus and methods for automated handling and embedding of tissue samples 有权
标题翻译：用于自动处理和嵌入组织样本的装置和方法
公开(公告)号：US08034292B2
公开(公告)日：2011-10-11
申请号：US13047053
申请日：2011-03-14
申请人： Douglas P. Allen , Dominic P. DiNovo , George A. Keller , Rebeccah P. Quam , Thomas J. Ward , Warren P. Williamson, IV
发明人： Douglas P. Allen , Dominic P. DiNovo , George A. Keller , Rebeccah P. Quam , Thomas J. Ward , Warren P. Williamson, IV
IPC分类号： G01N21/00
CPC分类号： G01N1/36 , G01N35/00732 , G01N2001/366 , Y10T436/2525 , Y10T436/2575
摘要： An automated machine for handling and embedding tissue samples contained on microtome sectionable supports. The machine includes an input member configured to hold a plurality of the microtome sectionable supports prior to a tissue embedding operation. An output member is configured to hold a plurality of the microtome sectionable supports after the tissue embedding operation. A cooling unit is configured to hold at least one of the microtome sectionable supports during the tissue embedding operation. A motorized carrier assembly is mounted for movement and configured to hold at least one of the microtome sectionable supports. The carrier assembly moves the support from the input member to the cooling unit and, finally, to the output member. A dispensing device dispenses an embedding material onto the microtome sectionable support and at least one tissue sample carried by the microtome sectionable support during the embedding operation.
摘要翻译：一种用于处理和嵌入包含在切片机可切片支架上的组织样本的自动化机器。该机器包括一个输入构件，构造成在组织嵌入操作之前保持多个切片机可切割支架。输出构件被配置为在组织嵌入操作之后保持多个切片机可切割支撑件。冷却单元构造成在组织嵌入操作期间保持切片机可分段支撑件中的至少一个。安装电动载体组件用于移动并且构造成保持切片机可分段支撑件中的至少一个。托架组件将支撑件从输入构件移动到冷却单元，最后移动到输出构件。分配装置在嵌入操作期间将嵌入材料分配到切片机可切片支撑件和由切片机可切割支撑件携带的至少一个组织样本。

16. 发明申请

US20110182783A1 TISSUE CASSETTE FOR AUTOMATED HANDLING AND EMBEDDING OF TISSUE SAMPLES 有权
标题翻译：用于组织样品的自动处理和嵌入的组织样品盒
公开(公告)号：US20110182783A1
公开(公告)日：2011-07-28
申请号：US13047044
申请日：2011-03-14
申请人： Warren P. Williamson, IV , Thomas J. Ward , Stephen P. Whitlatch
发明人： Warren P. Williamson, IV , Thomas J. Ward , Stephen P. Whitlatch
IPC分类号： B01L3/00
CPC分类号： G01N1/36 , G01N35/00732 , G01N2001/366 , Y10T436/2525 , Y10T436/2575
摘要： An automated machine for handling and embedding tissue samples contained on microtome sectionable supports. The machine includes an input member configured to hold a plurality of the microtome sectionable supports prior to a tissue embedding operation. An output member is configured to hold a plurality of the microtome sectionable supports after the tissue embedding operation. A cooling unit is configured to hold at least one of the microtome sectionable supports during the tissue embedding operation. A motorized carrier assembly is mounted for movement and configured to hold at least one of the microtome sectionable supports. The carrier assembly moves the support from the input member to the cooling unit and, finally, to the output member. A dispensing device dispenses an embedding material onto the microtome sectionable support and at least one tissue sample carried by the microtome sectionable support during the embedding operation.
摘要翻译：一种用于处理和嵌入包含在切片机可切片支架上的组织样本的自动化机器。该机器包括一个输入构件，构造成在组织嵌入操作之前保持多个切片机可切割支架。输出构件被配置为在组织嵌入操作之后保持多个切片机可切割支撑件。冷却单元构造成在组织嵌入操作期间保持切片机可分段支撑件中的至少一个。安装电动载体组件用于移动并且构造成保持切片机可分段支撑件中的至少一个。托架组件将支撑件从输入构件移动到冷却单元，最后移动到输出构件。分配装置在嵌入操作期间将嵌入材料分配到切片机可切片支撑件和由切片机可切割支撑件携带的至少一个组织样本。

17. 发明授权

US5972004A Wire fasteners for use in minimally invasive surgery and apparatus and methods for handling those fasteners 失效
标题翻译：用于微创手术的线扣，用于处理这些紧固件的装置和方法
公开(公告)号：US5972004A
公开(公告)日：1999-10-26
申请号：US026671
申请日：1998-02-20
申请人： Warren P. Williamson, IV , Paul A. Spence , George A. Keller , Cecil R. Robinson , Thomas J. Ward
发明人： Warren P. Williamson, IV , Paul A. Spence , George A. Keller , Cecil R. Robinson , Thomas J. Ward
IPC分类号： A61B17/00 , A61B17/04 , A61B17/064 , A61B17/068 , A61B17/072 , A61B17/115 , A61B17/34 , A61B19/00 , A61F2/24
CPC分类号： A61B17/0469 , A61B17/0644 , A61B17/0684 , A61B17/072 , A61F2/2409 , A61F2/2427 , A61B17/0401 , A61B17/0467 , A61B17/0487 , A61B17/064 , A61B17/115 , A61B2017/00243 , A61B2017/0406 , A61B2017/0458 , A61B2017/0464 , A61B2017/047 , A61B2017/0641 , A61B2017/3486 , A61B2090/061 , A61B2090/395
摘要： Wire fasteners having legs with lengths that can be one hundred times the width of the fastener are used to secure items, such as prosthesis valves to a patient during minimally invasive surgery. The fasteners are manipulated into position and then are immobilized by means of the legs thereof for tensioning, cutting and forming in situ. The fasteners are manipulated, tensioned and formed from the leg end of the fasteners. Tools for initially placing the fasteners and for immobilizing, tensioning, cutting and bending the fastener legs are disclosed. Once the fasteners are initially placed, the prosthesis is placed on the long legs of the placed fasteners and is guided into position on the legs. Once the prosthesis is in position, the legs of the fasteners are immobilized, tensioned, cut and bent into staple-like shapes to secure the prosthesis to the patient. A method for carrying out the procedure using the long fastener is also disclosed. Using the teaching of the present disclosure, a surgeon can customize a fastener to the particular surgery or even to the particular portion of surgery being performed during the surgery.
摘要翻译：具有长度为紧固件宽度的一百倍的腿的电线紧固件用于在微创手术期间将物品（例如假体瓣膜）固定到患者。紧固件被操纵到位，然后通过其腿部固定，用于原位张紧，切割和成形。紧固件由紧固件的腿端被操纵，张紧和形成。公开了用于初始放置紧固件并固定，张紧，切割和弯曲紧固件腿的工具。一旦紧固件被初始放置，假体被放置在所放置的紧固件的长腿上并且被引导到腿上的位置。一旦假体就位，紧固件的腿被固定，张紧，切割并弯曲成钉状形状以将假体固定到患者身上。还公开了一种使用该长紧固件执行该过程的方法。使用本公开的教导，外科医生可以定制针对特定手术的紧固件，或甚至可以在手术期间执行手术的特定部分。

18. 发明授权

US08877146B2 Cassette for handling and holding tissue samples during processing, embedding and microtome procedures, and methods therefor 有权
标题翻译：用于在处理，嵌入和切片机程序期间处理和保持组织样品的盒，及其方法
公开(公告)号：US08877146B2
公开(公告)日：2014-11-04
申请号：US11618987
申请日：2007-01-02
申请人： Warren P. Williamson, IV , Thomas J. Ward , Stephen P. Whitlatch
发明人： Warren P. Williamson, IV , Thomas J. Ward , Stephen P. Whitlatch
IPC分类号： B01L9/00 , B01L3/00 , G01N1/31
CPC分类号： B01L3/545 , B01L2300/02 , G01N1/31 , G01N2001/315
摘要： A cassette for holding a tissue sample includes a body having a bottom wall and a plurality of side walls extending upwardly with respect to the bottom wall to define an interior space for receiving the tissue sample. A lid is configured to be received in the interior space, and the cassette is sectionable in a microtome. Sensing elements are associated with the body or lid and configured to allow an automated sensing system to determine at least one characteristic of the cassette. A flange extends along upper portions of at least two of the side walls and includes a plurality of holes. Other features are included to more effectively and efficiently manufacture and use the cassette.
摘要翻译：用于保持组织样本的盒包括具有底壁和相对于底壁向上延伸的多个侧壁的主体，以限定用于接收组织样本的内部空间。盖被配置为容纳在内部空间中，并且盒可在切片机中分段。感测元件与主体或盖相关联并且被配置为允许自动感测系统确定盒的至少一个特性。凸缘沿至少两个侧壁的上部延伸并且包括多个孔。包括其他功能，以更有效和高效地制造和使用磁带。

19. 发明授权

US06811555B1 Method and apparatus for performing anastomosis with eversion of tissue edges and joining of exposed intima of the everted tissue 失效
标题翻译：用于通过外翻组织边缘进行吻合的方法和装置，以及接合外露组织的暴露的内膜
公开(公告)号：US06811555B1
公开(公告)日：2004-11-02
申请号：US09654605
申请日：2000-09-01
申请人： Geoffrey H. Willis , Thomas A. Kramer , Paul A. Spence , George T. Christakis , Timothy J. McCoy , John W. Davis , Bradley D. Blackwood , Peter Callas , Michael Francis Wei , Jonathan L. Podmore , Andrew Knight , Thomas J. Ward , Warren P. Williamson, IV
发明人： Geoffrey H. Willis , Thomas A. Kramer , Paul A. Spence , George T. Christakis , Timothy J. McCoy , John W. Davis , Bradley D. Blackwood , Peter Callas , Michael Francis Wei , Jonathan L. Podmore , Andrew Knight , Thomas J. Ward , Warren P. Williamson, IV
IPC分类号： A61B1708
CPC分类号： A61B17/1152 , A61B17/11 , A61B17/115 , A61B2017/1107 , A61B2017/1132 , A61B2017/1135 , A61B2017/1139
摘要： A ring for use in anastomosis. Preferably, the ring is integrally formed from metal, and includes a ring portion and tines and docking members that extend from the ring portion. The ring portion and tines are malleable, and preferably also the docking members are malleable. The ring portion and tines are malleable in the sense that once deformed from a first shape into a second shape, they will not relax back into the first shape from the second. To install the ring in a vessel with the ring portion extending around an incision or other orifice, the tines pierce the tissue around the orifice and are curled against an anvil. The action of curling the tines inverts the tissue near the orifice edges to expose the inside surface of the vessel or organ. Other aspects of the invention are a method and apparatus for installing an anastomosis ring in an incision or other orifice in a vessel or other organ, a method and apparatus for precisely aligning two anastomosis rings (each installed in an incision or other orifice of a different organ) and fastening the aligned rings together. The clips can be crimped onto the aligned rings, or they can be spring clips which are sprung onto the aligned rings to clamp the rings together by spring force. Also within the scope of the invention are crimping and spring clips for use in fastening together two aligned anastomosis rings. In other embodiments, the invention is a method for performing an anastomosis by installing an anastomosis ring in an orifice in an organ, installing another anastomosis ring in an orifice in another organ, precisely aligning the two installed anastomosis rings, and fastening the aligned rings together.
摘要翻译：用于吻合的戒指。优选地，环由金属一体地形成，并且包括从环部延伸的环部分和尖齿和对接构件。环形部分和尖齿是可延展的，并且优选的是对接部件是可延展的。环形部分和尖齿在从第一形状变形成第二形状的意义上是可延展的，它们将不会从第二形状放松回第一形状。为了将环安装在具有围绕切口或其他孔口延伸的环部分的容器中，齿刺穿孔周围的组织并且卷绕在砧座上。卷曲尖齿的作用使孔边缘附近的组织反转以暴露血管或器官的内表面。本发明的其它方面是用于将吻合环安装在容器或其他器官中的切口或其它孔中的方法和装置，用于精确地对准两个吻合环（每个安装在切口或不同的其他孔中的其他孔中的方法和装置）器官）并将对准的环固定在一起。夹子可以压接在对准的环上，或者它们可以是弹簧夹，弹簧夹被弹簧上对准的环，以通过弹簧力将环夹在一起。也在本发明的范围内的是压接和弹簧夹，用于将两个对准的吻合环紧固在一起。在其他实施例中，本发明是一种通过在器官中的孔中安装吻合环来进行吻合的方法，在另一个器官的孔中安装另一个吻合环，精确对准两个安装的吻合环，并将对准的环固定在一起。

20. 发明授权

US6162233A Wire fasteners for use in minimally invasive surgery and means and methods for handling those fasteners 有权
标题翻译：用于微创手术的电线紧固件以及用于处理这些紧固件的装置和方法
公开(公告)号：US6162233A
公开(公告)日：2000-12-19
申请号：US369196
申请日：1999-08-06
申请人： Warren P. Williamson, IV , Paul A. Spence , George A. Keller , Cecil R. Robinson , Thomas J. Ward
发明人： Warren P. Williamson, IV , Paul A. Spence , George A. Keller , Cecil R. Robinson , Thomas J. Ward
IPC分类号： A61B17/00 , A61B17/04 , A61B17/064 , A61B17/068 , A61B17/072 , A61B17/115 , A61B17/34 , A61B19/00 , A61F2/24 , A61B17/10
CPC分类号： A61B17/0644 , A61B17/0401 , A61B17/0467 , A61B17/0469 , A61B17/0487 , A61B17/064 , A61B17/0684 , A61B17/072 , A61B17/115 , A61B2017/00243 , A61B2017/0406 , A61B2017/0454 , A61B2017/0464 , A61B2017/047 , A61B2017/0472 , A61B2017/07214 , A61B2017/07242 , A61B2017/3486 , A61B2090/061 , A61B2090/395 , A61F2/2409 , A61F2/2427
摘要： Wire fasteners having legs with lengths that can be one hundred times the width of the fastener are used to secure items, such as prosthesis valves to a patient during minimally invasive surgery. The fasteners are manipulated into position and then are immobilized by the legs thereof for tensioning, cutting and forming in situ. The fasteners are manipulated, tensioned and formed from the leg end of the fasteners. Tools for initially placing the fasteners and for immobilizing, tensioning, cutting and bending the fastener legs are disclosed. Once the fasteners are initially placed, the prosthesis is placed on the long legs of the placed fasteners and is guided into position on the legs. Once the prosthesis is in position, the legs of the fasteners are immobilized, tensioned, cut and bent into staple-like shapes to secure the prosthesis to the patient. A method for carrying out the procedure using the long fastener is also disclosed. Using the teaching of the present disclosure, a surgeon can customize a fastener to the particular surgery or even to the particular portion of surgery being performed during the surgery.
摘要翻译：具有长度为紧固件宽度的一百倍的腿的电线紧固件用于在微创手术期间将物品（例如假体瓣膜）固定到患者。紧固件被操纵到位，然后被其腿固定，用于张紧，切割和成形。紧固件由紧固件的腿端被操纵，张紧和形成。公开了用于初始放置紧固件并固定，张紧，切割和弯曲紧固件腿的工具。一旦紧固件被初始放置，假体被放置在所放置的紧固件的长腿上并被引导到腿上的位置。一旦假体就位，紧固件的腿被固定，张紧，切割并弯曲成钉状形状以将假体固定到患者身上。还公开了一种使用该长紧固件执行该过程的方法。使用本公开的教导，外科医生可以定制针对特定手术的紧固件，或甚至可以在手术期间执行手术的特定部分。

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