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11. 发明申请

US20170100452A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF AXONAL AND NEURONAL DEGENERATION 审中-公开
公开(公告)号：US20170100452A1
公开(公告)日：2017-04-13
申请号：US15384065
申请日：2016-12-19
申请人： Thien Nguyen
发明人： Thien Nguyen
IPC分类号： A61K38/08
CPC分类号： A61K38/08 , A61K9/0019 , A61K38/06 , A61K38/07 , A61K38/10 , A61K38/12 , C07K5/0817 , C07K5/1019 , C07K7/06 , C07K7/08 , C07K7/64 , C07K14/001
摘要： The present invention generally relates to methods and compositions for preventing or treating axonal and/or neuronal degeneration in a subject by administering a composition comprising a peptide that comprises the amino acid sequence Arginine-Glycine-Aspartate (RGD).

12. 发明申请

US20130316033A1 NOVEL BACTERIUM AND EXTRACTS OF SAID BACTERIUM AND THE USE OF SAME IN DERMATOLOGY 有权
公开(公告)号：US20130316033A1
公开(公告)日：2013-11-28
申请号：US13997029
申请日：2011-12-22
申请人： Philippe Lebaron , Muriel Bourrain , Nathalie Castex-Rizzi , Thien Nguyen
发明人： Philippe Lebaron , Muriel Bourrain , Nathalie Castex-Rizzi , Thien Nguyen
IPC分类号： A61K35/74
CPC分类号： A61K35/74 , A61K8/99 , A61K2800/40 , A61Q19/007 , A61Q19/10 , C12N1/20 , C12R1/36
摘要： The present invention relates to a novel bacterial strain isolated from groundwater. The invention also relates to bacterial extracts and to the use of same in the context of the treatment of inflammations. More particularly, the present invention relates to novel compositions of interest in the treatment and the prevention of inflammatory disorders, notably dermatological pathologies.

13. 发明授权

US08162697B1 Tip-sleeve silent plug with 360° sliding ring contact 有权
标题翻译：尖头袖子静音插头，360°滑环接触
公开(公告)号：US08162697B1
公开(公告)日：2012-04-24
申请号：US12965416
申请日：2010-12-10
申请人： Paolo Menolotto , Thien Nguyen
发明人： Paolo Menolotto , Thien Nguyen
IPC分类号： H01R24/04
CPC分类号： H01R13/7031 , H01R24/58 , H01R2103/00
摘要： A silent plug includes a switch adapted to be automatically opened when the connector is inserted into the jack and closed when the connector is not inserted into the jack to eliminate electronically generated noise that would otherwise occur when the plug is inserted. The switch has a sliding ring contact for providing the electrical connection between the tip contact and the ground sleeve and providing 360° contact with the ground sleeve via a bridging contact. A spring applies a force in the mating direction to urge the sliding ring contact into the closed position. An actuator facing the jack contacts the front face of the jack when the connector is inserted into the jack in order to urge the sliding ring contact in a direction opposite to the mating direction and against the force applied by the spring.
摘要翻译：无声插头包括适于在连接器插入插座时自动打开的开关，并且当连接器未插入插座时闭合，以消除当插头插入时将发生的电子产生的噪声。开关具有滑环接触件，用于提供尖端触头和接地套筒之间的电连接，并通过桥接触点与接地套筒提供360°接触。弹簧在配合方向上施加力以促使滑环接触进入关闭位置。面向千斤顶的致动器在插头插入插座时接触插座的前面，以便在与配合方向相反的方向上推动滑环接触并抵抗由弹簧施加的力。

14. 发明申请

US20060148196A1 SEMICONDUCTOR FABRICATION PROCESS INCLUDING RECESSED SOURCE/DRAIN REGIONS IN AN SOI WAFER 有权
标题翻译：半导体制造工艺，包括SOI WAFER中的残留源/漏区
公开(公告)号：US20060148196A1
公开(公告)日：2006-07-06
申请号：US11028811
申请日：2005-01-03
申请人： Voon-Yew Thean , Brian Goolsby , Bich-Yen Nguyen , Thien Nguyen , Tab Stephens
发明人： Voon-Yew Thean , Brian Goolsby , Bich-Yen Nguyen , Thien Nguyen , Tab Stephens
IPC分类号： H01L21/76
CPC分类号： H01L29/66636 , H01L29/66772 , H01L29/78639
摘要： A method of forming a transistor with recessed source/drains in an silicon-on-insulator (SOI) wafer includes forming isolation structures in an active layer of the wafer, where the isolation structures preferably extend through the active layer to a BOX layer of the wafer. An upper portion of the active layer is removed to form a transistor channel structure. A gate dielectric is formed on the channel structure and a gate structure is formed on the gate dielectric. Etching through exposed portions of the gate dielectric, channel structure, and BOX layer is performed and source/drain structures are then grown epitaxially from exposed portions of the substrate bulk. The isolation structure and the BOX layer are both comprised primarily of silicon oxide and the thickness of the isolation structure prevents portions of the BOX layer from being etched.
摘要翻译：在绝缘体上硅（SOI）晶片中形成具有凹陷源/漏极的晶体管的方法包括在晶片的有源层中形成隔离结构，其中隔离结构优选地延伸穿过有源层到BOX层的BOX层晶圆。去除有源层的上部以形成晶体管沟道结构。在沟道结构上形成栅极电介质，在栅极电介质上形成栅极结构。执行蚀刻通过栅介质，沟道结构和BOX层的暴露部分，然后从衬底体的暴露部分外延生长源极/漏极结构。隔离结构和BOX层主要由氧化硅组成，并且隔离结构的厚度防止BOX层的部分被蚀刻。

15. 发明授权

US6122509A Method and system for automatically connecting a call at a selected time in a radio telecommunications network 失效
标题翻译：用于在无线电电信网络中在选定时间自动连接呼叫的方法和系统
公开(公告)号：US6122509A
公开(公告)日：2000-09-19
申请号：US939590
申请日：1997-09-29
申请人： Thien Nguyen
发明人： Thien Nguyen
IPC分类号： H04W4/12 , H04M11/00
CPC分类号： H04W4/12
摘要： A method and system for automatically setting up a call in a radio telecommunications network. The system includes a first mobile switching center (MSC) servicing and controlling an area where a originating MS is located and a home location register (HLR) associated with the first MSC. The originating MS sends data which includes the selected time and a destination number of a terminating party. Within the HLR is service logic which determines when the selected time has arrived and initiates the call. Upon determining that the originating MS is idle and available, the HLR establishes a voice channel between the first MSC and the originating MS. Additionally, the HLR establishes a voice channel between the terminating party and a second MSC if the terminating party is a mobile station. The system also records a message for delivery at the selected time to the originating party. Additionally, the terminating party may be a telephone in the Public Switched Telephone Network (PSTN).
摘要翻译：一种用于在无线电电信网络中自动建立呼叫的方法和系统。该系统包括：服务和控制发起MS所在区域的第一移动交换中心（MSC）和与第一MSC相关联的归属位置寄存器（HLR）。始发MS发送包括所选择的时间的数据和终止方的目的地号码。在HLR内是服务逻辑，其确定所选择的时间何时到达并发起呼叫。在确定始发MS空闲并且可用时，HLR在第一MSC和始发MS之间建立语音信道。此外，如果终止方是移动台，则HLR在终端和第二MSC之间建立语音信道。该系统还将在所选择的时间向发起方记录用于传送的消息。此外，终端方可以是公共交换电话网（PSTN）中的电话。

16. 发明授权

US09913877B2 Methods and compositions for the treatment of axonal and neuronal degeneration 有权
公开(公告)号：US09913877B2
公开(公告)日：2018-03-13
申请号：US14747960
申请日：2015-06-23
申请人： Osefame Ewaleifoh , Thien Nguyen
发明人： Osefame Ewaleifoh , Thien Nguyen
IPC分类号： C07K5/09 , C07K7/64 , A61K38/08 , C07K5/11 , C07K7/06 , C07K7/08 , C07K14/00 , A61K38/06 , A61K38/07 , A61K38/10 , A61K38/12 , A61K9/00
CPC分类号： A61K38/08 , A61K9/0019 , A61K38/06 , A61K38/07 , A61K38/10 , A61K38/12 , C07K5/0817 , C07K5/1019 , C07K7/06 , C07K7/08 , C07K7/64 , C07K14/001
摘要： The present invention generally relates to methods and compositions for preventing or treating axonal and/or neuronal degeneration in a subject by administering a composition comprising a peptide that comprises the amino acid sequence Arginine-Glycine-Aspartate (RGD).

17. 发明授权

US09486486B2 Bacterium and extracts of said bacterium and the use of same in therapy 有权
标题翻译：所述细菌的细菌和提取物及其在治疗中的用途
公开(公告)号：US09486486B2
公开(公告)日：2016-11-08
申请号：US13997022
申请日：2011-12-22
申请人： Nathalie Castex-Rizzi , Thien Nguyen , Christine Libon , Bertrand Chol
发明人： Nathalie Castex-Rizzi , Thien Nguyen , Christine Libon , Bertrand Chol
IPC分类号： C12N1/20 , A61K35/74 , A61K39/095 , C07K14/22 , C12R1/01 , A61K39/00
CPC分类号： A61K35/74 , A61K39/095 , A61K2039/55594 , C07K14/22 , C12N1/20 , C12R1/01
摘要： The present invention relates to a novel bacterial strain isolated and characterized from groundwater. The invention also relates to bacterial extracts and to the therapeutic use of same, notably in the context of the treatment of inflammations.
摘要翻译：本发明涉及从地下水分离和表征的新型细菌菌株。本发明还涉及细菌提取物及其治疗用途，特别是在治疗炎症的情况下。

18. 发明申请

US20160193279A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF AXONAL AND NEURONAL DEGENERATION 审中-公开
公开(公告)号：US20160193279A1
公开(公告)日：2016-07-07
申请号：US14747960
申请日：2015-06-23
申请人： Osefame Ewaleifoh , Thien Nguyen
发明人： Osefame Ewaleifoh , Thien Nguyen
IPC分类号： A61K38/08 , A61K9/00 , A61K38/12
CPC分类号： A61K38/08 , A61K9/0019 , A61K38/06 , A61K38/07 , A61K38/10 , A61K38/12 , C07K5/0817 , C07K5/1019 , C07K7/06 , C07K7/08 , C07K7/64 , C07K14/001
摘要： The present invention generally relates to methods and compositions for preventing or treating axonal and/or neuronal degeneration in a subject by administering a composition comprising a peptide that comprises the amino acid sequence Arginine-Glycine-Aspartate (RGD).

19. 发明授权

US08452921B1 Provisioning a pass-through disk in a virtualized computing environment 有权
公开(公告)号：US08452921B1
公开(公告)日：2013-05-28
申请号：US12725793
申请日：2010-03-17
申请人： Song Li , Thien Nguyen
发明人： Song Li , Thien Nguyen
IPC分类号： G06F12/00
CPC分类号： G06F9/45533 , G06F3/0607 , G06F3/0631 , G06F3/0664 , G06F3/0665 , G06F3/067 , G06F9/4555
摘要： A physical host machine determines that a storage device from a network storage system is available to the host machine as a pass-through disk. Virtualization software running on the host machine assigns the pass-through disk to a temporary resource group on the host machine. The pass-through disk is logically attached to the virtual machine running on the host machine and made available to an operating system and application running on the virtual machine.

20. 发明申请

US20080131450A1 Immunogenic complexes, preparation method thereof and use of same in pharmaceutical compositions 审中-公开
标题翻译：免疫原性复合物及其制备方法及其在药物组合物中的应用
公开(公告)号：US20080131450A1
公开(公告)日：2008-06-05
申请号：US11976085
申请日：2007-10-19
申请人： Christine Libon , Thien Nguyen
发明人： Christine Libon , Thien Nguyen
IPC分类号： A61K39/12 , A61K39/00
CPC分类号： C07K14/005 , A61K39/00 , A61K39/385 , A61K2039/6068 , A61K2039/6075 , C12N2760/18522
摘要： The present invention relates to a method of improving the immunogenicity of an immunogen, by means of coupling with a small support peptide. More specifically, the present invention relates to a method of preparing an immunogenic complex, as well as the complexes that can be obtained by one such method, and the use of said complexes as a drug in order to increase the immunogenicity of an immunogen. The invention comprises, for example, a support peptide which is coupled with a peptide from the respiratory syncytial virus (RSV) G protein and the use thereof, alone or comprising as a combination product a RSV F protein or subunit thereof, as a vaccine for the treatment of RSV-related respiratory infections.
摘要翻译：本发明涉及通过与小支持肽偶联来提高免疫原的免疫原性的方法。更具体地，本发明涉及制备免疫原性复合物的方法，以及可以通过一种这样的方法获得的复合物以及所述复合物作为药物的用途，以增加免疫原的免疫原性。本发明包括例如与来自呼吸道合胞病毒（RSV）G蛋白的肽偶联的支持肽及其单独的或作为RSV F蛋白或其亚基的组合产物包含的用途作为疫苗的疫苗治疗RSV相关呼吸道感染。

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