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11. 发明授权

US08197529B2 Removable stent-graft 有权
标题翻译：可移植支架移植物
公开(公告)号：US08197529B2
公开(公告)日：2012-06-12
申请号：US12491895
申请日：2009-06-25
申请人： Edward H. Cully , Erin B. Hutchinson , Michael J. Vonesh , Woodrow W. Watson
发明人： Edward H. Cully , Erin B. Hutchinson , Michael J. Vonesh , Woodrow W. Watson
IPC分类号： A61F2/06
CPC分类号： A61F2/07 , A61B2017/22035 , A61F2/848 , A61F2/88 , A61F2/89 , A61F2002/072 , A61F2002/075 , A61F2002/9528 , A61F2220/005 , A61F2250/0071
摘要： A removable device such as a stent-graft, intended for applications where it may be desirable to remove the device at some time following implantation. The stent-graft of the present invention includes a helically-wound stent component provided with a covering of graft material. It is removable by gripping an end of the helically-wound stent component with a retrieval device and applying tension to the stent component in the direction in which it is intended to be withdrawn from the site of implantation. The use of such a retrieval device allows the stent-graft to be removed remotely, such as via a catheter inserted into the body at a different location from the implantation site. The design of the stent-graft is such that the stent component is extended axially while the adjacent portion of the graft separates between windings of the stent component. The axial extension of the stent component, with portions of the graft still joined to the stent component, allows the device to be “unraveled” (or “unwound”) and removed through a catheter of diameter adequately small to be inserted into the body cavity that contained the stent-graft. It is removed atraumatically, without incurring significant trauma to the body conduit in which it had been deployed.
摘要翻译：诸如支架移植物的可移除装置，其用于在植入后的某个时间可能需要移除装置的应用。本发明的支架移植物包括设置有移植材料覆盖物的螺旋缠绕的支架组件。通过用拾取装置抓住螺旋缠绕的支架部件的一端并且沿着其将要从植入部位取出的方向对支架部件施加张力，其可移除。使用这种检索装置允许远程地移除支架移植物，例如通过在与植入部位不同的位置插入体内的导管。支架移植物的设计使得支架部件沿轴向延伸，而移植物的相邻部分在支架部件的绕组之间分离。支架部件的轴向延伸，其中移植物的一部分仍然连接到支架部件，允许装置“解开”（或“展开”）并通过足够小的直径的导管移除以插入体腔包含支架移植物。它无创伤地去除，而不会对其部署的身体导管造成重大创伤。

12. 发明申请

US20110276012A1 PUNCTURABLE CATHETER 有权
标题翻译：可拆卸导管
公开(公告)号：US20110276012A1
公开(公告)日：2011-11-10
申请号：US13186198
申请日：2011-07-19
申请人： JOSEPH R. ARMSTRONG , Edward H. Cully , Keith M. Flury , Michael J. Vonesh
发明人： JOSEPH R. ARMSTRONG , Edward H. Cully , Keith M. Flury , Michael J. Vonesh
IPC分类号： A61M25/00
CPC分类号： A61M25/0043 , A61F2/958 , A61M25/005 , A61M25/0052 , A61M25/10 , A61M2025/0183 , A61M2025/0188 , A61M2025/1056 , A61M2025/1081
摘要： A catheter provided with a guidewire catheter lumen having a thin covering that is easily punctured by a guidewire at virtually any desired point along the catheter length. The thin covering may be integral with the catheter shaft, or may be a separate component that covers only the portion of the catheter shaft immediately adjacent the outer portion of the guidewire lumen, or may be a thin tubular construct that surrounds the entire catheter shaft. The covering is preferably relatively translucent, allowing for good visualization of the location of the end of the guidewire to enable puncturing of the covering at the desired location along the length of the catheter shaft. The covering is also preferably tear resistant at puncture sites. The catheter shaft is preferably made of a material having a color that provides good visibility against an operating field, and more preferably is phosphorescent either entirely or in part. Materials suitable for the catheter shaft are polymeric materials well known in the art; the catheter shaft may optionally be provided with metallic stiffening components such as wires or hypotubes along all or part of the catheter length.
摘要翻译：导管，其具有导线导管管腔，该导管管腔具有薄的覆盖层，其在导管长度的几乎任何所需点处被导丝容易地刺穿。薄的覆盖物可以与导管轴成一体，或者可以是仅覆盖导管轴的紧邻导丝管腔的外部的部分的单独的部件，或者可以是围绕整个导管轴的薄的管状结构。覆盖物优选地是相对半透明的，允许良好地可视化导丝端部的位置，以使得能够沿着导管轴的长度在期望的位置刺穿覆盖物。覆盖物也优选在穿刺部位具有抗撕裂性。导管轴优选由具有对操作场提供良好可见性的颜色的材料制成，更优选地，全部或部分地是磷光。适用于导管轴的材料是本领域公知的聚合材料; 导管轴可以可选地沿着导管长度的全部或部分设置有金属加强部件，例如电线或海波管。

13. 发明申请

US20110276011A1 PUNCTURABLE CATHETER 审中-公开
公开(公告)号：US20110276011A1
公开(公告)日：2011-11-10
申请号：US13186156
申请日：2011-07-19
申请人： JOSEPH R. ARMSTRONG , Edward H. Cully , Keith M. Flur , Michael J. Vonesh
发明人： JOSEPH R. ARMSTRONG , Edward H. Cully , Keith M. Flur , Michael J. Vonesh
IPC分类号： A61M25/00
CPC分类号： A61M25/0043 , A61F2/958 , A61M25/005 , A61M25/0052 , A61M25/10 , A61M2025/0183 , A61M2025/0188 , A61M2025/1056 , A61M2025/1081
摘要： A catheter provided with a guidewire catheter lumen having a thin covering that is easily punctured by a guidewire at virtually any desired point along the catheter length. The thin covering may be integral with the catheter shaft, or may be a separate component that covers only the portion of the catheter shaft immediately adjacent the outer portion of the guidewire lumen, or may be a thin tubular construct that surrounds the entire catheter shaft. The covering is preferably relatively translucent, allowing for good visualization of the location of the end of the guidewire to enable puncturing of the covering at the desired location along the length of the catheter shaft. The covering is also preferably tear resistant at puncture sites. The catheter shaft is preferably made of a material having a color that provides good visibility against an operating field, and more preferably is phosphorescent either entirely or in part. Materials suitable for the catheter shaft are polymeric materials well known in the art; the catheter shaft may optionally be provided with metallic stiffening components such as wires or hypotubes along all or part of the catheter length.

14. 发明申请

US20110118769A1 AORTIC DISSECTION SEPTAL CUTTING TOOL 有权
标题翻译：动态隔离切割工具
公开(公告)号：US20110118769A1
公开(公告)日：2011-05-19
申请号：US12620360
申请日：2009-11-17
申请人： Cody L. Bliss , Edward H. Cully , Joel M. Greene , Joshua J. Lovekamp , Michael C. Nilson , Himanshu Jagdish Patel , David M. Williams , William P. Witort
发明人： Cody L. Bliss , Edward H. Cully , Joel M. Greene , Joshua J. Lovekamp , Michael C. Nilson , Himanshu Jagdish Patel , David M. Williams , William P. Witort
IPC分类号： A61B17/22
CPC分类号： A61B17/320016 , A61B17/3201 , A61B17/32075 , A61B18/1492 , A61B2017/00778 , A61B2017/22039 , A61B2017/22052 , A61B2017/22069 , A61M25/003 , A61M2025/0037
摘要： The present invention relates to medical cutting tools for treating aortic septal dissections. The cutting tool is provided with a delivery catheter and has a remotely actuated cutting blade or cutting wire component. The cutting tool is provided with at least one displacement element. The displacement element assists in placement of the cutting tool at a desired location. The displacement element also assists in maintaining contact between the cutting blade and tissue being cut.
摘要翻译：本发明涉及用于治疗主动脉间隔解剖的医疗切割工具。切割工具设置有输送导管，并且具有远程致动的切割刀片或切割线部件。切割工具设置有至少一个位移元件。位移元件有助于将切割工具放置在期望的位置。位移元件还有助于保持切割刀片和被切割的组织之间的接触。

15. 发明申请

US20100049294A1 Controlled deployable medical device and method of making the same 审中-公开
公开(公告)号：US20100049294A1
公开(公告)日：2010-02-25
申请号：US12478331
申请日：2009-06-04
申请人： Stanislaw L. Zukowski , Edward H. Cully , Keith M. Flury , Michelle L. Gendron
发明人： Stanislaw L. Zukowski , Edward H. Cully , Keith M. Flury , Michelle L. Gendron
IPC分类号： A61F2/84
CPC分类号： A61F2/954 , A61F2/07 , A61F2002/065 , A61F2002/9505 , A61F2002/9511 , A61F2002/9534
摘要： Controlled deployable medical devices that are retained inside a body passage and in one particular application to vascular devices used in repairing arterial dilations, e.g., aneurysms. Such devices can be adjusted during deployment, thereby allowing at least one of a longitudinal or radial re-positioning, resulting in precise alignment of the device to an implant target site.

16. 发明授权

US07625337B2 Catheter assembly 有权
标题翻译：导管总成
公开(公告)号：US07625337B2
公开(公告)日：2009-12-01
申请号：US11500836
申请日：2006-08-07
申请人： Carey V. Campbell , Edward H. Cully , Sherif Eskaros , George N. Foutrakis , James William Mann , Peter J. Roeber , Benjamin M. Trapp , Michael J. Vonesh
发明人： Carey V. Campbell , Edward H. Cully , Sherif Eskaros , George N. Foutrakis , James William Mann , Peter J. Roeber , Benjamin M. Trapp , Michael J. Vonesh
IPC分类号： A61B1/12 , A61M29/00
CPC分类号： A61M25/10 , A61F2/958 , A61M25/0023 , A61M25/0029 , A61M25/0032 , A61M25/0043 , A61M25/005 , A61M25/0051 , A61M25/0052 , A61M25/0053 , A61M25/1002 , A61M25/1011 , A61M2025/0034 , A61M2025/0035 , A61M2025/0063 , A61M2025/0183 , A61M2025/0188 , A61M2025/1056 , A61M2025/1081
摘要： Novel catheter constructions comprising thin covering or wrapping materials such as polymer films. A catheter provided with a guidewire catheter lumen having a thin covering that is easily punctured by a guidewire at virtually any desired point along the catheter length. The thin covering may be integral with the catheter shaft, or may be a separate component that covers only the portion of the catheter shaft immediately adjacent the outer portion of the guidewire lumen, or may be a thin tubular construct that surrounds the entire catheter shaft. Moreover, polymer film can be used in combination with one or more elements to produce novel catheter constructions.
摘要翻译：新颖的导管结构包括薄的覆盖物或包裹材料如聚合物膜。导管，其具有导线导管管腔，该导管管腔具有薄的覆盖层，其在导管长度的几乎任何所需点处被导丝容易地刺穿。薄的覆盖物可以与导管轴成一体，或者可以是仅覆盖导管轴的紧邻导丝管腔的外部的部分的单独的部件，或者可以是围绕整个导管轴的薄的管状结构。此外，聚合物膜可以与一种或多种元素组合使用以产生新的导管结构。

17. 发明授权

US07556641B2 Deployment system for an expandable device 有权
标题翻译：可扩展设备的部署系统
公开(公告)号：US07556641B2
公开(公告)日：2009-07-07
申请号：US10892934
申请日：2004-07-16
申请人： Edward H. Cully , Keith M. Flury , Michael J. Vonesh
发明人： Edward H. Cully , Keith M. Flury , Michael J. Vonesh
IPC分类号： A61F2/06
CPC分类号： A61F2/966 , A61F2/95 , A61F2/958 , A61F2/97 , A61F2002/9511
摘要： The present invention is directed to a deployment system for an endoluminal device. The deployment system includes a confining sheath placed around a compacted endoluminal device. A deployment line is provided in the system that is an integral extension of the sheath. As the deployment line is actuated, the sheath retracts from around the compacted endoluminal device. As the sheath retracts from around the endoluminal device, material from the sheath may be converted into deployment line. Once the sheath is retracted from around the compacted endoluminal device, the endoluminal device expands in configuration and repairs vascular or cardiac structures of an implant recipient. Any remaining sheath material is removed from the implantation site along with the deployment line. The deployment system also includes an endo-prosthesis mounting member placed between the endoluminal device and an underlying catheter. The endo-prosthesis mounting member serves to cushion and retain the endoluminal device when constrained by the sheath and may assist in expansion of the endoluminal device when unconstrained by the sheath.The present invention is also directed to a deployment system having a deployment assembly that simultaneously expands an endo-prosthesis mounting member while removing a sheath from an expandable medical device.
摘要翻译：本发明涉及一种用于腔内装置的部署系统。部署系统包括围绕压实的腔内装置放置的限制鞘。在系统中提供了一个部署线，该线是护套的整体延伸。随着部署线被致动，护套从紧凑的腔内装置周围缩回。当护套从内腔装置周围缩回时，来自护套的材料可以被转换成展开线。一旦护套从紧凑的腔内装置周围缩回，腔内装置在构型上扩张并修复植入物接受者的血管或心脏结构。任何剩余的护套材料与植入线一起从植入部位移除。所述展开系统还包括放置在腔内装置和下面的导管之间的内腔假体安装构件。假体内固定构件用于在被护套约束时缓冲和保持内腔装置，并且可以在不受护套约束时有助于内腔装置的膨胀。本发明还涉及一种具有展开组件的展开系统，所述展开组件在从可扩张医疗装置移除护套的同时同时展开内衣假体安装构件。

18. 发明申请

US20080262601A1 Stent Device with Multiple Helix Construction 审中-公开
标题翻译：具有多个螺旋结构的支架装置
公开(公告)号：US20080262601A1
公开(公告)日：2008-10-23
申请号：US12146656
申请日：2008-06-26
申请人： Edward H. Cully , Michael J. Vonesh
发明人： Edward H. Cully , Michael J. Vonesh
IPC分类号： A61F2/88
CPC分类号： A61F2/915 , A61F2/91 , A61F2002/91516 , A61F2002/91525 , A61F2002/91533 , A61F2002/9155 , A61F2002/91558 , A61F2220/0033 , A61F2220/005 , A61F2230/0013 , A61F2230/0054
摘要： An improved stent design is disclosed that employs a series of helically oriented expansion elements encircling the stent. Each of the expansion elements includes a stepped pattern employing two distinct pitch angles. The expansion elements are oriented to cooperate with each other to form a series of virtual radially expandable rings that provide suitable outward force for proper stent function, but which are not connected together to form a continuous coherent ring if separated from the stent as a whole. In this manner, a distinctive stent design is provided that has numerous functional benefits over stents described in the prior art.
摘要翻译：公开了一种改进的支架设计，其采用环绕支架的一系列螺旋定向的膨胀元件。每个膨胀元件包括采用两个不同倾斜角的阶梯形图案。膨胀元件被定向成彼此配合以形成一系列虚拟的可径向扩张的环，其提供用于适当的支架功能的合适的向外的力，但如果与整个支架分离，则它们不连接在一起以形成连续的相干环。以这种方式，提供了与现有技术中描述的支架相比具有许多功能益处的独特的支架设计。

19. 发明授权

US06899727B2 Deployment system for intraluminal devices 有权
标题翻译：管腔内装置的部署系统
公开(公告)号：US06899727B2
公开(公告)日：2005-05-31
申请号：US09767314
申请日：2001-01-22
申请人： Joseph P. Armstrong , Edward H. Cully , Edward E. Shaw , Mark J. Ulm , Michael J. Vonesh
发明人： Joseph P. Armstrong , Edward H. Cully , Edward E. Shaw , Mark J. Ulm , Michael J. Vonesh
IPC分类号： A61F2/86 , A61F2/06
CPC分类号： A61F2/97 , A61F2/86 , A61F2/95 , A61F2/958 , A61F2002/9511 , A61F2002/9522 , A61F2002/9583 , A61F2250/0071
摘要： A constraining sheath for use around an endoprosthesis (e.g., a stent device, with or without a graft covering), which may be a balloon expandable endoprosthesis but more preferably is a self-expanding prosthesis. The endoprosthesis is coaxially enclosed within the constraining sheath, which is an outer, disruptable, preferably implantable tubular sheath, preferably made of ePTFE. The constraining sheath and endoprosthesis are preferably mounted together as an assembly on an angioplasty balloon for delivery. Deployment of the endoprosthesis entails inflating the angioplasty balloon to a pressure sufficient to disrupt or break the constraining sheath in a prescribed fashion, thereby allowing a self-expanding endoprosthesis to spontaneously deploy. The constraining sheath of ePTFE may be attached to the endoprosthesis and implanted along with the device, or alternatively attached to the balloon catheter shaft and removed with the balloon catheter.
摘要翻译：用于内置假体周围使用的约束护套（例如，具有或不具有移植物覆盖物的支架装置），其可以是球囊可膨胀内置假体，但更优选是自膨胀假体。内置假体同轴地封闭在约束护套内，约束鞘是外部的，可破坏的，优选可植入的管状护套，优选地由ePTFE制成。约束鞘和内假体优选地作为组件安装在血管成形术气囊上用于递送。内窥镜假体的部署需要将血管成形术气囊膨胀至足以以规定的方式破坏或打破约束鞘的压力，从而允许自膨胀内置假体自发部署。 ePTFE的约束鞘可以连接到内置假体并与装置一起植入，或者替代地附接到球囊导管轴并且用球囊导管去除。

20. 发明授权

US10213329B2 Evertable sheath devices, systems, and methods 有权
公开(公告)号：US10213329B2
公开(公告)日：2019-02-26
申请号：US13571296
申请日：2012-08-09
申请人： Edward H. Cully , Craig W. Irwin , James D. Silverman
发明人： Edward H. Cully , Craig W. Irwin , James D. Silverman
IPC分类号： A61F2/966 , A61F2/958 , A61F2/82 , A61F2/95
摘要： The present disclosure comprises devices, systems, and methods having an inverted sheath configured to cover, and in some instances constrain, a medical device and to retract through eversion, thus enabling the deployment of medical device at the treatment site. A constraining sheath can evert hydraulically. A constraining sheath can be configured to neck down a medical device to achieve a lower delivery profile. Furthermore, a constraining sheath can comprise a balloon to expand or positionally or structurally adjust a medical device.

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