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11. 发明申请

WO2022261368A1 ATRAUMATIC TIP FOR EXPANDABLE AND RECOVERABLE SHEATH 审中-公开
公开(公告)号：WO2022261368A1
公开(公告)日：2022-12-15
申请号：PCT/US2022/032902
申请日：2022-06-09
申请人： EDWARDS LIFESCIENCES CORPORATION
发明人： TRAN, Sonny , TAMIR, Ilan , LEE, Jeong, Soo , FINE, Maxwell, Harrison , SALEH, Nasser, William , MAK, Sovanpheap , NGUYEN, Tien, Thi , BULMAN, Erik , MAIMON, David
IPC分类号： A61M25/06 , A61M25/00 , A61F2/24 , A61L29/12
摘要： Various systems and devices are described herein pertaining to expandable sheaths (4400). Sheath aspects are described that include a flexible sheath tip that is expandable and bendable. The sheath includes a radially expandible proximal end and a radially expandable distal end. The sheath tip includes a plurality of layers (4408,4426,4410) that expand to accept a medical device traveling axially and bi-directionally therethrough with minimal deformation of the sheath tip, wherein an intermediate layer (4426) extends distally beyond an inner liner layer (4408) and an elastomeric outer layer (4410) to define a distal end of a tip section, wherein at least the inner liner layer defines a slit (4412) extending distally along at least a portion of the tip section.

12. 发明申请

WO2016164082A1 EXPANDABLE SHEATH WITH ELASTOMERIC CROSS SECTIONAL PORTIONS 审中-公开
标题翻译：具有弹性横截面部分的可膨胀的管道
公开(公告)号：WO2016164082A1
公开(公告)日：2016-10-13
申请号：PCT/US2015/065578
申请日：2015-12-14
申请人： EDWARDS LIFESCIENCES CORPORATION
发明人： ZHOU, Pu , BULMAN, Erik , GAO, Yong , BIAN, Baigui , ZHU, Yidong, M. , WILLIAMS, David, Delon
IPC分类号： A61M29/00 , A61M29/02
CPC分类号： A61F2/2427 , A61F2/97 , A61F2250/0018 , A61M25/0054 , A61M25/01 , A61M25/0662 , A61M25/0668 , A61M2025/0024 , A61M2025/0681
摘要： An expandable introducer sheath for passage of implant delivery catheters, such as catheters for delivery of prosthetic heart valves. The expandable sheath balances the amounts, shapes and positions of various stiff and elastic structures in the sheath to selectively program the expandability and buckling stiffness of the sheath. The expandable sheath can include, for example, an expandable tubular layer that includes alternating stiff and elastic wall portions of a single radial thickness. The combination of stiff and elastic wall portions allow for torque and push strength to advance the expandable sheath while at the same time accommodating temporary expansion. The expandable sheath can also be reinforced with a tubular layer of braided fibers or a stent structure for additional strength. Other embodiments include selective use of slots or gaps at the distal end of a stiff wall portion to enhance expandability and distribute strain.
摘要翻译：用于植入物输送导管（例如用于输送假体心脏瓣膜的导管）通过的可扩张的导引鞘。可扩张护套平衡护套中各种刚性和弹性结构的数量，形状和位置，以选择性地编程护套的可膨胀性和屈曲刚度。可膨胀护套可以包括例如包括单个径向厚度的交替的刚性和弹性壁部分的可膨胀管状层。刚性和弹性壁部分的组合允许扭矩和推动强度推进可膨胀护套，同时容纳临时膨胀。可膨胀护套还可以用编织纤维的管状层或用于附加强度的支架结构来增强。其他实施例包括在刚性壁部分的远端选择性地使用槽或间隙以增强可扩展性和分布应变。

13. 发明申请

WO2006007305A3 METHODS AND DEVICES FOR DIRECTIONALLY ABLATING TISSUE 审中-公开
公开(公告)号：WO2006007305A3
公开(公告)日：2006-01-19
申请号：PCT/US2005/019962
申请日：2005-06-06
申请人： EDWARDS LIFESCIENCES CORPORATION , WARD, Jim , NIEMAN, Tim , MURPHY, John , DANG, Ninh, Huu , PRUITT, Tazi , BULMAN, Erik
发明人： WARD, Jim , NIEMAN, Tim , MURPHY, John , DANG, Ninh, Huu , PRUITT, Tazi , BULMAN, Erik
IPC分类号： A61B18/14
摘要： Ablation instruments and methods are disclosed for ablating diseased tissue such as cardiac tissue. The method includes introducing a flexible elongate member into a predetermined tissue site with a flexible elongate member having a proximal end, a distal end and a longitudinal lumen extending therebetween. A slidable conductor is positioned through the lumen proximate to the tissue site and energy is transmitted to the distal end of the elongate member through the conductor. The flexible elongate member is both longitudinally flexible and resists twisting during bending. The target tissue is ablated, coagulated or photochemically modulated without damaging surrounding tissue.

14. 发明申请

WO2021226421A1 EXPANDABLE SHEATH FOR INTRODUCING AN ENDOVASCULAR DELIVERY DEVICE INTO A BODY 审中-公开
公开(公告)号：WO2021226421A1
公开(公告)日：2021-11-11
申请号：PCT/US2021/031227
申请日：2021-05-07
申请人： EDWARDS LIFESCIENCES CORPORATION
发明人： FINE, Maxwell, Harrison , TAMIR, Iian , LEE, Jeong, Soo , TRAN, Sonny , GAFFNEY, Leah, Paige , BULMAN, Erik , SALEH, Nasser, William
IPC分类号： A61M25/06 , A61M25/00
摘要： Examples of an expandable sheath can be used in conjunction with a catheter assembly to introduce a prosthetic device, such as a heart valve, into a patient. Such examples can minimize trauma to the vessel by allowing for temporary expansion of a portion of the introducer sheath to accommodate the delivery apparatus, followed by a return to the original diameter once the prosthetic device passes through. Some examples can include a sheath with inner and outer layers, where a folded portion of the inner layer extends through a slit in the outer layer and a portion of the outer layer overlaps the folded portion of the inner layer. Some examples include an elastic outer cover positioned outside the outer layer. Examples of the present expandable sheath can avoid the need for multiple insertions for the dilation of the vessel, thus offering advantages over prior art introducer sheaths.

15. 发明申请

WO2021225940A1 DELIVERY SYSTEMS AND DELIVERY ASSEMBLIES FOR PROSTHETIC HEART VALVES, METHODS OF MAKING AND USING THE SAME 审中-公开
公开(公告)号：WO2021225940A1
公开(公告)日：2021-11-11
申请号：PCT/US2021/030427
申请日：2021-05-03
申请人： EDWARDS LIFESCIENCES CORPORATION
发明人： BULMAN, Erik
IPC分类号： A61F2/24 , A61M25/01
摘要： Disclosed herein are delivery systems and delivery assemblies comprising a co-extruded elongated polymeric sleeve comprising an inner polymer layer and an outer polymer layer, which form two lumens having a different diameter, wherein the inner polymer layer comprises a fluoropolymer; and wherein the outer polymer layer comprises a polyamide, or a polyether block amide, or a combination thereof. Also disclosed are methods of making and using the same.

16. 发明申请

WO2020023294A1 METHODS OF MAKING AN EXPANDABLE SHEATH 审中-公开
公开(公告)号：WO2020023294A1
公开(公告)日：2020-01-30
申请号：PCT/US2019/042531
申请日：2019-07-19
申请人： EDWARDS LIFESCIENCES CORPORATION
发明人： BULMAN, Erik , NGUYEN, Duy , NGUYEN, Kim, D.
IPC分类号： B29C48/23 , B29C48/21 , B29C48/11 , A61M25/00 , A61M25/06
摘要： Disclosed herein are expandable introducer sheaths and methods of making and using the same. The sheaths minimize trauma to a patient's vasculature by allowing for temporary expansion of a portion of the sheath (1) to accommodate passage of a delivery system for a cardiovascular device, then return to a non-expanded state after the passage of the device. The sheath (1) includes an elongated annular member (10) through which the cardiovascular device and its delivery system pass. In an embodiment, the annular inner member can be formed by coextruding a first and second material (165, 167). The first material (165) includes a fold, and the second material (167) radially spaces the different parts of the fold from each other during fabrication and provides support for maintaining the tubular structure. The second material (167) is removed once the coextrusion process is complete.

17. 发明申请

WO2017040284A1 CONTROLLED BALLOON DEPLOYMENT 审中-公开
标题翻译：控制气球部署
公开(公告)号：WO2017040284A1
公开(公告)日：2017-03-09
申请号：PCT/US2016/048995
申请日：2016-08-26
申请人： EDWARDS LIFESCIENCES CORPORATION
发明人： ZHU, Yidong, M. , ZHOU, Pu , BULMAN, Erik , BIAN, Baigui
IPC分类号： A61F2/958 , A61F2/24
CPC分类号： A61F2/2433 , A61F2/958 , A61F2250/0039 , A61M2025/1059 , A61M2025/1081
摘要： The methods and devices disclosed herein promote temporal control of balloon inflation patterns. The devices include a covering for a portion of the balloon that compresses the balloon portion during the inflation process. This enables the distal portion of a balloon to be inflated prior to the proximal portion of a balloon, creating a tapered shape at lower inflation pressures. This is especially useful during transvascular implantation procedures, as it prevents dislodgement of an implant mounted on the balloon. As inflation continues, pressure exerted on the balloon by the covering is overcome such that the proximal region of the balloon inflates, forming a shape with generally straighter sides than the tapered shape, thereby expanding the cardiovascular device.
摘要翻译：本文公开的方法和装置促进球囊充气模式的时间控制。这些装置包括用于在膨胀过程期间压缩气囊部分的气囊的一部分的覆盖物。这使得球囊的远端部分在球囊的近端部分之前被充气，在较低的充气压力下产生锥形形状。这在经血管植入手术期间特别有用，因为它可防止安装在气囊上的植入物的移位。当膨胀持续时，通过覆盖物施加在气囊上的压力被克服，使得球囊的近侧区域膨胀，形成具有比锥形形状大致更直的侧面的形状，从而使心血管装置膨胀。

18. 发明申请

WO2016164079A1 EXPANDABLE SHEATH 审中-公开
标题翻译：可膨胀的沙子
公开(公告)号：WO2016164079A1
公开(公告)日：2016-10-13
申请号：PCT/US2015/065089
申请日：2015-12-10
申请人： EDWARDS LIFESCIENCES CORPORATION
发明人： ZHOU, Pu , BULMAN, Erik , GEISER, Timothy, A. , VALDEZ, Michael, G. , ZHU, Yidong, M. , BIAN, Baigui , TRAN, Sonny , WHITE, Richard, D. , LE, Thanh, Huy , LE, Tung, T. , GOWDAR, Alpana, Kiran
IPC分类号： A61M25/00 , A61M25/06
CPC分类号： A61M25/0662 , A61F2/2433 , A61F2/958 , A61F2002/011 , A61M25/0023 , A61M2025/0024
摘要： A delivery sheath includes an elastic outer tubular layer and an inner tubular layer having a thick wall portion integrally connected to a thin wall portion. The inner tubular layer can have a compressed or folded condition wherein the thin wall portion folds onto an outer surface of the thick wall portion under urging of the elastic outer tubular layer. When an implant passes therethrough, the outer tubular layer stretches and the inner tubular layer unfolds into an expanded lumen diameter. Once the implant passes, the outer tubular layer again urges the inner tubular layer into the compressed condition with the sheath reassuming its smaller profile. The sheath may also include selectively placed longitudinal rods that mediate friction between the inner and outer tubular layers to facilitate easy expansion and collapse, thereby reducing the push force needed to advance the implant through the sheath's lumen.
摘要翻译：输送护套包括弹性外管状层和内管状层，其具有与薄壁部分一体连接的厚壁部分。内部管状层可以具有压缩或折叠状态，其中薄壁部分在弹性外部管状层的推动下折叠到厚壁部分的外表面上。当植入物通过其中时，外管层延伸并且内管层展开成扩张的内腔直径。一旦植入物通过，外管层再次促使内管层进入压缩状态，护套重建其较小的轮廓。护套还可以包括选择性地放置的纵向杆，其介导内部和外部管状层之间的摩擦，以便于容易的膨胀和塌缩，从而减少使植入物通过护套的内腔所需的推动力。

20. 发明公开

EP3340945A1 CONTROLLED BALLOON DEPLOYMENT 有权
公开(公告)号：EP3340945A1
公开(公告)日：2018-07-04
申请号：EP16842686.4
申请日：2016-08-26
申请人： Edwards Lifesciences Corporation
发明人： ZHU, Yidong, M. , ZHOU, Pu , BULMAN, Erik , BIAN, Baigui
IPC分类号： A61F2/958 , A61F2/24
CPC分类号： A61F2/2433 , A61F2/958 , A61F2250/0039 , A61M2025/1059 , A61M2025/1081
摘要： The methods and devices disclosed herein promote temporal control of balloon inflation patterns. The devices include a covering for a portion of the balloon that compresses the balloon portion during the inflation process. This enables the distal portion of a balloon to be inflated prior to the proximal portion of a balloon, creating a tapered shape at lower inflation pressures. This is especially useful during transvascular implantation procedures, as it prevents dislodgement of an implant mounted on the balloon. As inflation continues, pressure exerted on the balloon by the covering is overcome such that the proximal region of the balloon inflates, forming a shape with generally straighter sides than the tapered shape, thereby expanding the cardiovascular device.

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