专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明授权

US6145391A Charged particle neutralizing apparatus and method of neutralizing charged particles 有权
标题翻译：带电粒子中和装置和中和带电粒子的方法
公开(公告)号：US6145391A
公开(公告)日：2000-11-14
申请号：US437035
申请日：1999-11-09
申请人： David Y. H. Pui , Da-Ren Chen
发明人： David Y. H. Pui , Da-Ren Chen
IPC分类号： B01J19/08 , B05B5/00 , H01T23/00 , H05F3/00 , H05F3/04 , G01N1/28
CPC分类号： B05B5/002 , B01J19/081 , B01J19/088 , H01T23/00 , H05F3/00 , H05F3/04 , B01J2219/0813 , B01J2219/083 , B01J2219/0849 , B01J2219/0879
摘要： A method for use in neutralizing a charged discharge includes providing a neutralizer housing having a longitudinal axis extending between an inlet and an outlet thereof. A charged discharge is introduced into the inlet of the neutralizer housing for flow parallel to the inlet of the longitudinal axis from the inlet to the outlet. An alternating electric field is created within the housing parallel to the longitudinal axis for directing bursts of negatively charged ions and positively charged ions alternately towards the inlet for use in neutralizing the charged discharge. An apparatus for carrying out this method is also described.
摘要翻译：用于中和充电放电的方法包括提供具有在其入口和出口之间延伸的纵向轴线的中和器壳体。带电的排放物被引入到中和器壳体的入口中，以从入口到出口平行于纵向轴线的入口流动。在壳体内平行于纵向轴线产生交变电场，用于将带负电荷的离子和带正电荷的离子交替地引向入口以用于中和充电的放电。还描述了用于执行该方法的装置。

12. 发明授权

US06093557A Electrospraying apparatus and method for introducing material into cells 失效
标题翻译：用于将材料引入电池的电喷雾装置和方法
公开(公告)号：US06093557A
公开(公告)日：2000-07-25
申请号：US92794
申请日：1998-06-05
申请人： David Y. H. Pui , Da-Ren Chen
发明人： David Y. H. Pui , Da-Ren Chen
IPC分类号： A61K39/00 , A61K48/00 , B01J2/00 , B01J2/04 , B05B5/025 , B05B5/03 , B05B5/053 , B05B5/08 , C12M3/00 , C12N15/82 , C12N15/87 , C12N15/89 , C12N13/00
CPC分类号： B01J2/006 , B01J2/04 , B05B5/025 , B05B5/03 , B05B5/0533 , B05B5/081 , B05B5/082 , B05B5/084 , B05B5/087 , C12M35/02 , C12N15/8207 , C12N15/87 , C12N15/895 , A61K39/00 , A61K48/00 , B01J2219/00371 , B01J2219/00436 , B05B13/04
摘要： A method of introducing biological material into cells includes providing one or more target cells and establishing a spray of substantially dispersed particles including biological material. The substantially dispersed particles have an electrical charge applied thereto such that one or more of the substantially dispersed particles of the spray is introduced into one or more of the target cells. The spray of substantially dispersed particles may be established by dispensing a spray of microdroplets suspending particles. The electrical charge is concentrated on the suspended particles as the microdroplet evaporates. The suspended particles may include carrier particles with biological material or the suspended particles may be particles of biological material alone. The space charge effect of the concentrated electrical charge on the substantially dispersed particles of the spray enable one or more of the particles to be introduced into one or more of the target cells.
摘要翻译：将生物材料引入细胞的方法包括提供一个或多个靶细胞并建立包括生物材料的基本上分散的颗粒的喷雾。基本上分散的颗粒具有施加到其上的电荷，使得一个或多个基本分散的喷雾颗粒被引入一个或多个靶细胞。基本上分散的颗粒的喷雾可以通过分配微滴悬浮颗粒的喷雾来建立。当微滴蒸发时，电荷集中在悬浮颗粒上。悬浮颗粒可以包括具有生物材料的载体颗粒，或悬浮颗粒可以是单独的生物材料颗粒。浓缩电荷对基本分散的喷雾颗粒的空间电荷效应使得一个或多个颗粒被引入到一个或多个靶细胞中。

13. 发明授权

US5992244A Charged particle neutralizing apparatus and method of neutralizing charged particles 失效
标题翻译：带电粒子中和装置和中和带电粒子的方法
公开(公告)号：US5992244A
公开(公告)日：1999-11-30
申请号：US34433
申请日：1998-03-04
申请人： David Y. H. Pui , Da-Ren Chen
发明人： David Y. H. Pui , Da-Ren Chen
IPC分类号： B01J19/08 , B05B5/00 , H01T23/00 , H05F3/00 , H05F3/04 , G01N1/28
CPC分类号： B05B5/002 , B01J19/081 , B01J19/088 , H01T23/00 , H05F3/00 , H05F3/04 , B01J2219/0813 , B01J2219/083 , B01J2219/0849 , B01J2219/0879
摘要： Neutralizing a charged discharge includes providing a neutralizer housing having a longitudinal axis extending between an inlet and an outlet of the neutralizer housing. A charged discharge having a first polarity is introduced into the inlet of the neutralizer housing for flow parallel to the longitudinal axis from the inlet to the outlet. A stream of ions having a second polarity opposite the first polarity is directed to flow parallel to the longitudinal axis of the neutralizer housing towards the inlet for use in neutralizing the charged discharge. An electrode configuration is operable to create an electric field within the neutralizer housing for use in directing the stream of ions to flow parallel to the longitudinal axis of the neutralizer housing towards the inlet.
摘要翻译：使充电的放电中和包括提供具有在中和器壳体的入口和出口之间延伸的纵向轴线的中和器壳体。具有第一极性的带电放电被引入中和器壳体的入口，用于从入口到出口平行于纵向轴线流动。具有与第一极性相反的第二极性的离子流被引导成平行于中和器壳体的纵向轴线朝向入口流动以用于中和充电的放电。电极配置可操作以在中和器壳体内产生电场，用于引导离子流平行于中和器壳体的纵向轴线朝向入口流动。

14. 发明授权

US08044350B2 Miniaturized ultrafine particle sizer and monitor 有权
标题翻译：小型化超细粒度仪和显示器
公开(公告)号：US08044350B2
公开(公告)日：2011-10-25
申请号：US12325884
申请日：2008-12-01
申请人： Da-Ren Chen , Chaolong Qi
发明人： Da-Ren Chen , Chaolong Qi
IPC分类号： H01J49/00
CPC分类号： G01N27/64 , G01N15/0266 , Y10T29/49826
摘要： An apparatus for measuring particle size distribution includes a charging device and a precipitator. The charging device includes a corona that generates charged ions in response to a first applied voltage, and a charger body that generates a low energy electrical field in response to a second applied voltage in order to channel the charged ions out of the charging device. The corona tip and the charger body are arranged relative to each other to direct a flow of particles through the low energy electrical field in a direction parallel to a direction in which the charged ions are channeled out of the charging device. The precipitator receives the plurality of particles from the charging device, and includes a disk having a top surface and an opposite bottom surface, wherein a predetermined voltage is applied to the top surface and the bottom surface to precipitate the plurality of particles.
摘要翻译：用于测量粒度分布的装置包括充电装置和除尘器。充电装置包括响应于第一施加电压产生带电离子的电晕;以及充电器主体，其响应于第二施加电压而产生低能量电场，以将带电离子引出充电装置。电晕末端和充电器主体相对于彼此布置以引导颗粒流沿平行于带电离子从充电装置引出的方向的方向通过低能电场。除尘器从充电装置接收多个颗粒，并且包括具有顶表面和相对底表面的盘，其中向顶表面和底表面施加预定电压以沉淀多个颗粒。

15. 发明申请

US20110139970A1 Nanoscale Object Detection Using A Whispering Gallery Mode Resonator 有权
标题翻译：使用耳语画廊模式谐振器的纳米级对象检测
公开(公告)号：US20110139970A1
公开(公告)日：2011-06-16
申请号：US12966785
申请日：2010-12-13
申请人： Lina He , Jiangang Zhu , Sahin Kaya Ozdemir , Lan Yang , Da-Ren Chen
发明人： Lina He , Jiangang Zhu , Sahin Kaya Ozdemir , Lan Yang , Da-Ren Chen
IPC分类号： G01J9/00
CPC分类号： G01N21/7746
摘要： Detection of individual objects using a light source and a whispering gallery mode (WGM) resonator. Light from the whispering gallery mode (WGM) resonator is analyzed. The presence of an object is determined based on mode splitting associated with the light received by the photodetector. For example, the presence of the object may be determined based on the distance between two whispering gallery modes and/or the linewidths of the two modes in a transmission spectrum. Alternatively, the presence of the object may be determined based on a beat frequency that is determined based on a heterodyne beat signal produced by combining split laser modes in the received light from a WGM microcavity laser.
摘要翻译：使用光源和耳语画廊模式（WGM）谐振器检测各个物体。分析了来自耳语堂模式（WGM）谐振器的光。基于与由光电检测器接收的光相关联的模式分割来确定对象的存在。例如，可以基于两个耳语画廊模式之间的距离和/或发送频谱中的两种模式的线宽来确定对象的存在。或者，可以基于基于通过在来自WGM微腔激光器的接收光中组合分割激光模式而产生的外差拍频确定的拍频来确定对象的存在。

16. 发明申请

US20060266132A1 Stackable differential mobility analyzer for aerosol measurement 失效
标题翻译：用于气溶胶测量的可堆叠差动移动分析仪
公开(公告)号：US20060266132A1
公开(公告)日：2006-11-30
申请号：US11240161
申请日：2005-09-30
申请人： Meng-Dawn Cheng , Da-Ren Chen
发明人： Meng-Dawn Cheng , Da-Ren Chen
IPC分类号： G01N15/00
CPC分类号： G01N15/0266
摘要： A multi-stage differential mobility analyzer (MDMA) for aerosol measurements includes a first electrode or grid including at least one inlet or injection slit for receiving an aerosol including charged particles for analysis. A second electrode or grid is spaced apart from the first electrode. The second electrode has at least one sampling outlet disposed at a plurality different distances along its length. A volume between the first and the second electrode or grid between the inlet or injection slit and a distal one of the plurality of sampling outlets forms a classifying region, the first and second electrodes for charging to suitable potentials to create an electric field within the classifying region. At least one inlet or injection slit in the second electrode receives a sheath gas flow into an upstream end of the classifying region, wherein each sampling outlet functions as an independent DMA stage and classifies different size ranges of charged particles based on electric mobility simultaneously.
摘要翻译：用于气溶胶测量的多级差速移动分析仪（MDMA）包括第一电极或栅格，其包括至少一个入口或注入狭缝，用于接收含有用于分析的带电粒子的气溶胶。第二电极或栅极与第一电极间隔开。第二电极具有沿着其长度以多个不同距离设置的至少一个采样出口。第一和第二电极或栅格之间的入口或注入狭缝与多个采样出口中的远端之间的体积形成分类区域，第一和第二电极用于充电到合适的电位以在分类中产生电场地区。第二电极中的至少一个入口或注入狭缝接收到分类区域的上游端的鞘气流，其中每个采样出口用作独立的DMA级，并且基于电迁移率同时对不同尺寸的带电粒子范围进行分类。

17. 发明申请

US20100001184A1 MINIATURIZED ULTRAFINE PARTICLE SIZER AND MONITOR 有权
标题翻译：微型超细颗粒尺寸和监测器
公开(公告)号：US20100001184A1
公开(公告)日：2010-01-07
申请号：US12325884
申请日：2008-12-01
申请人： Da-Ren Chen , Chaolong Qi
发明人： Da-Ren Chen , Chaolong Qi
IPC分类号： G01N23/00 , B23P11/00
CPC分类号： G01N27/64 , G01N15/0266 , Y10T29/49826
摘要： An apparatus for measuring particle size distribution includes a charging device and a precipitator. The charging device includes a corona that generates charged ions in response to a first applied voltage, and a charger body that generates a low energy electrical field in response to a second applied voltage in order to channel the charged ions out of the charging device. The corona tip and the charger body are arranged relative to each other to direct a flow of particles through the low energy electrical field in a direction parallel to a direction in which the charged ions are channeled out of the charging device. The precipitator receives the plurality of particles from the charging device, and includes a disk having a top surface and an opposite bottom surface, wherein a predetermined voltage is applied to the top surface and the bottom surface to precipitate the plurality of particles.
摘要翻译：用于测量粒度分布的装置包括充电装置和除尘器。充电装置包括响应于第一施加电压产生带电离子的电晕;以及充电器主体，其响应于第二施加电压而产生低能量电场，以将带电离子引出充电装置。电晕末端和充电器主体相对于彼此布置以引导颗粒流沿平行于带电离子从充电装置引出的方向的方向通过低能电场。除尘器从充电装置接收多个颗粒，并且包括具有顶表面和相对底表面的盘，其中向顶表面和底表面施加预定电压以沉淀多个颗粒。

18. 发明申请

US20080141936A1 Electrospraying apparatus and method for coating particles 有权
标题翻译：电喷雾装置和涂布颗粒的方法
公开(公告)号：US20080141936A1
公开(公告)日：2008-06-19
申请号：US11906998
申请日：2007-10-04
申请人： David Y.H. Pui , Da-Ren Chen
发明人： David Y.H. Pui , Da-Ren Chen
IPC分类号： B05B5/025
CPC分类号： B01J2/006 , A61K39/00 , A61K48/00 , B01J2/04 , B01J2219/00371 , B01J2219/00436 , B05B5/025 , B05B5/03 , B05B5/0533 , B05B5/081 , B05B5/082 , B05B5/084 , B05B5/087 , B05B13/04 , C12M35/02 , C12N15/8207 , C12N15/87 , C12N15/895
摘要： An electrospraying apparatus and/or method is used to coat particles. For example, a flow including at least one liquid suspension may be provided through at least one opening at a spray dispenser end. The flow includes at least particles and a coating material. A spray of microdroplets suspending at least the particles is established forward of the spray dispenser end by creating a nonuniform electrical field between the spray dispenser end and an electrode electrically isolated therefrom. The particles are coated with at least a portion of the coating material as the microdroplet evaporates. For example, the suspension may include biological material particles.
摘要翻译：使用电喷雾装置和/或方法来涂覆颗粒。例如，可以通过喷雾分配器端部的至少一个开口提供包括至少一个液体悬浮液的流。流动至少包括颗粒和涂层材料。通过在喷雾分配器端部与与其分离的电极之间产生不均匀的电场，在喷雾分配器端的前方建立悬浮至少颗粒的微滴喷雾。当微滴蒸发时，颗粒被涂覆有至少一部分涂层材料。例如，悬浮液可以包括生物材料颗粒。

19. 发明申请

US20060177573A1 Coating medical devices 有权
公开(公告)号：US20060177573A1
公开(公告)日：2006-08-10
申请号：US11390606
申请日：2006-03-28
申请人： David Pui , Da-Ren Chen
发明人： David Pui , Da-Ren Chen
IPC分类号： A61L33/00 , B05D3/00 , B05D1/12
CPC分类号： B05B5/0255 , A61F2/86 , A61L31/10 , A61L31/16 , A61L2300/00 , A61L2300/622 , A61L2420/02 , B05B1/14 , B05B5/025 , B05B5/03 , B05B5/0533 , B05B5/08 , B05B5/082 , B05B7/066 , B05B7/0884 , B05B13/0228 , B05D1/002 , B05D1/04 , B05D1/045
摘要： Methods and systems for coating at least a portion of a medical device (e.g., a stent structure) include providing a plurality of coating particles (e.g., monodisperse coating particles) in a defined volume. For example, the particles may be provided using one or more nozzle structures, wherein each nozzle structure includes at least one opening terminating at a dispensing end. The plurality of coating particles may be provided in the defined volume by dispensing a plurality of microdroplets having an electrical charge associated therewith from the dispensing ends of the one or more nozzle structures through use of a nonuniform electrical field between the dispensing ends and the medical device. Electrical charge is concentrated on the particle as the microdroplet evaporates. With a plurality of coating particles provided in the defined volume, such particles can be moved towards at least one surface of the medical device to form a coating thereon (e.g., using an electric field and/or a thermophoretic effect).

20. 发明申请

US20090266924A1 HIGH MASS THROUGHPUT PARTICLE GENERATION USING MULTIPLE NOZZLE SPRAYING 审中-公开
标题翻译：使用多个喷嘴喷射的高质量颗粒物生成
公开(公告)号：US20090266924A1
公开(公告)日：2009-10-29
申请号：US12395100
申请日：2009-02-27
申请人： David Y.H. Pui , Da-Ren Chen
发明人： David Y.H. Pui , Da-Ren Chen
IPC分类号： B05B5/00
CPC分类号： B05B5/032 , A61F2/86 , B05B1/14 , B05B5/025 , B05B5/0255 , B05B5/08 , B05B5/087 , B05B7/0408 , B05B7/066 , B05B13/06
摘要： Spraying apparatus and methods that employ multiple nozzle structures for producing multiple sprays of particles, e.g., nanoparticles, for various applications, e.g., pharmaceuticals, are provided. For example, an electrospray dispensing device may include a plurality of nozzle structures, wherein each nozzle structure is separated from adjacent nozzle structures by an internozzle distance. Sprays of particles are established from the nozzle structures by creating a nonuniform electrical field between the nozzle structures and an electrode electrically isolated therefrom.
摘要翻译：提供了使用多个喷嘴结构来产生多种喷雾剂的喷涂设备和方法，例如纳米颗粒，用于各种应用，例如药物。例如，电喷雾分配装置可以包括多个喷嘴结构，其中每个喷嘴结构通过内部喷嘴距离与相邻喷嘴结构分离。通过在喷嘴结构和与其电隔离的电极之间产生不均匀的电场，从喷嘴结构建立颗粒喷雾。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式