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11. 发明申请

US20090163574A1 Stable Pharmaceutical Composition Containing Docetaxel and a Method of Manufacturing the Same 失效
标题翻译：含有多西紫杉醇的稳定药物组合物及其制造方法
公开(公告)号：US20090163574A1
公开(公告)日：2009-06-25
申请号：US12301700
申请日：2007-05-22
申请人： Nam Ho Kim , Jin Young Lee , Jae-Sun Kim , Nam Kyu Lee , Woo Jae Jang , Joon Gyo Oh , Yoon-Jung Lee , Woong Sik Kim , Jin-Heung Sung , Key An Um
发明人： Nam Ho Kim , Jin Young Lee , Jae-Sun Kim , Nam Kyu Lee , Woo Jae Jang , Joon Gyo Oh , Yoon-Jung Lee , Woong Sik Kim , Jin-Heung Sung , Key An Um
IPC分类号： A61K31/337
CPC分类号： A61K9/0019 , A61K9/19 , A61K31/337 , A61K31/724 , A61K47/10 , A61K47/32 , A61K47/38 , A61K47/40 , A61K2300/00
摘要： The present invention relates to a stable pharmaceutical composition for injection containing docetaxel and a method of preparing the same. More particularly, the present invention relates to a pharmaceutical composition for injection containing docetaxel having better storage stability than conventional medications, which is prepared by dissolving docetaxel, a water-insoluble compound, in distilled water after mixing it with cyclodextrin (CD) and a water-soluble polymer such as hydroxypropyl methylcellulose (HPMC), polyethylene glycol (PEG) or polyvinylpyrrolidone (PVP) and lyophilizing the mixture, and a method of preparing the same.
摘要翻译：本发明涉及含有多西紫杉醇的稳定的注射用药物组合物及其制备方法。更具体地说，本发明涉及含有多西紫杉醇的药物组合物，其具有比常规药物更好的储存稳定性，其通过将多巴紫杉醇，水不溶性化合物与环糊精（CD）和水混合后在蒸馏水中溶解而制备可溶性聚合物如羟丙基甲基纤维素（HPMC），聚乙二醇（PEG）或聚乙烯吡咯烷酮（PVP），并将混合物冷冻干燥及其制备方法。

12. 发明申请

US20100069632A1 SALTS OF PYRROLOPYRIMIDINONE DERIVATIVES AND PROCESS FOR PREPARING THE SAME 审中-公开
标题翻译：吡咯烷酮衍生物的制备方法及其制备方法
公开(公告)号：US20100069632A1
公开(公告)日：2010-03-18
申请号：US12307144
申请日：2007-07-03
申请人： Nam Ho Kim , Jin-Young Lee , Jae-Sun Kim , Nam Kyu Lee , Woo Jae Jang , Joo Gyo Oh , Yoon-Jung Lee , Won-No Youn , Jin-Heung Sung , Key An Um
发明人： Nam Ho Kim , Jin-Young Lee , Jae-Sun Kim , Nam Kyu Lee , Woo Jae Jang , Joo Gyo Oh , Yoon-Jung Lee , Won-No Youn , Jin-Heung Sung , Key An Um
IPC分类号： C07D487/04
CPC分类号： C07D487/04
摘要： The present invention relates to salts of a pyrrolopyrimidinone derivative having superior PDE-5 inhibition activity and a process for preparing the same. More particularly, the present invention relates to a crystalline acid addition salt prepared by reacting a pyrrolopyrimidinone derivative with an acid selected from gentisic acid, maleic acid, citric acid, fumaric acid and tartaric acid. With no hygroscopic property and superior long-term storage stability, photostability and thermal stability, the salts of the pyrrolopyrimidinone derivative are appropriate to be prepared into medications and, with superior PDE-5 inhibition activity, are useful for the treatment and prevention of erectile dysfunction, pulmonary arterial hypertension, chronic obstructive pulmonary disease, benign prostatic hypertrophy and lower urinary tract diseases.
摘要翻译：本发明涉及具有优异的PDE-5抑制活性的吡咯并嘧啶酮衍生物的盐及其制备方法。更具体地，本发明涉及通过使吡咯并嘧啶酮衍生物与选自龙胆酸，马来酸，柠檬酸，富马酸和酒石酸的酸反应制备的结晶酸加成盐。无吸湿性和优异的长期储存稳定性，光稳定性和热稳定性，吡咯并嘧啶酮衍生物的盐适于制备成药物，并且具有优异的PDE-5抑制活性，可用于治疗和预防勃起功能障碍肺动脉高压，慢性阻塞性肺疾病，良性前列腺肥大和下尿路疾病。

13. 发明授权

US08791152B2 Stable pharmaceutical composition containing docetaxel and a method of manufacturing the same 失效
标题翻译：含有多西紫杉醇的稳定的药物组合物及其制造方法
公开(公告)号：US08791152B2
公开(公告)日：2014-07-29
申请号：US12301700
申请日：2007-05-22
申请人： Nam Ho Kim , Jin Young Lee , Jae-Sun Kim , Nam Kyu Lee , Woo Jae Jang , Joon Gyo Oh , Yoon-Jung Lee , Woong Sik Kim , Jin-Heung Sung , Key An Um
发明人： Nam Ho Kim , Jin Young Lee , Jae-Sun Kim , Nam Kyu Lee , Woo Jae Jang , Joon Gyo Oh , Yoon-Jung Lee , Woong Sik Kim , Jin-Heung Sung , Key An Um
IPC分类号： A61K31/335
CPC分类号： A61K9/0019 , A61K9/19 , A61K31/337 , A61K31/724 , A61K47/10 , A61K47/32 , A61K47/38 , A61K47/40 , A61K2300/00
摘要： The present invention relates to a stable pharmaceutical composition for injection containing docetaxel and a method of preparing the same. More particularly, the present invention relates to a pharmaceutical composition for injection containing docetaxel having better storage stability than conventional medications, which is prepared by dissolving docetaxel, a water-insoluble compound, in distilled water after mixing it with cyclodextrin (CD) and a water-soluble polymer such as hydroxypropyl methylcellulose (HPMC), polyethylene glycol (PEG) or polyvinylpyrrolidone (PVP) and lyophilizing the mixture, and a method of preparing the same.
摘要翻译：本发明涉及含有多西紫杉醇的稳定的注射用药物组合物及其制备方法。更具体地说，本发明涉及含有多西紫杉醇的药物组合物，其具有比常规药物更好的储存稳定性，其通过将多巴紫杉醇，水不溶性化合物与环糊精（CD）和水混合后在蒸馏水中溶解而制备可溶性聚合物如羟丙基甲基纤维素（HPMC），聚乙二醇（PEG）或聚乙烯吡咯烷酮（PVP），并将混合物冷冻干燥及其制备方法。

14. 发明授权

US07696351B2 Process for the preparation of S-(+)-clopidogrel by optical resolution 失效
标题翻译：通过光学拆分制备S - （+） - 氯吡格雷的方法
公开(公告)号：US07696351B2
公开(公告)日：2010-04-13
申请号：US12159145
申请日：2006-12-20
申请人： Jae-Sun Kim , Nam Ho Kim , Nam Kyu Lee , Jin Young Lee
发明人： Jae-Sun Kim , Nam Ho Kim , Nam Kyu Lee , Jin Young Lee
IPC分类号： C07D495/04
CPC分类号： C07D495/04
摘要： The present invention relates to a process for the preparation of S-(+)-clopidogrel by an optical resolution and, more particularly, to a process for the preparation of S-(+)-clopidogrel represented by the following formula 1 with high optical purity by converting a clopidogrel racemic carboxylic acid into a diastereomeric salt using a (+)-cinchonine for optical resolution, extracting an S-(+)-clopidogrel carboxylic acid from the diastereomeric salt using a suitable solvent under an acidic condition and then reacting the S-(+)-clopidogrel carboxylic acid with methanol.
摘要翻译：本发明涉及一种通过光学拆分制备S - （+） - 氯吡格雷的方法，更具体地说，涉及用高光学制备由下式1表示的S - （+） - 氯吡格雷的方法通过使用（+） - 辛可宁将氯吡格雷外消旋羧酸转化为非对映体盐进行光学拆分，使用合适的溶剂在酸性条件下从非对映异构体盐中提取S - （+） - 氯吡格雷羧酸，然后使 S - （+） - 氯吡格雷羧酸与甲醇。

15. 发明授权

US08144111B2 Light emitting diode driving circuit having voltage detection 有权
标题翻译：具有电压检测的发光二极管驱动电路
公开(公告)号：US08144111B2
公开(公告)日：2012-03-27
申请号：US12251176
申请日：2008-10-14
申请人： Jin Hwan Kim , Nam Kyu Lee , Doo Ho Yoo , Young Jong Yoo
发明人： Jin Hwan Kim , Nam Kyu Lee , Doo Ho Yoo , Young Jong Yoo
IPC分类号： G09G3/36
CPC分类号： H05B33/0815 , G09G3/342 , G09G2320/064 , G09G2330/04 , H05B33/0827 , Y02B20/347
摘要： There is provided a driving circuit of a light emitting device. The driving circuit of a light emitting may include: a DC/DC converter converting an input DC voltage into an output DC voltage; a light emitting device block including a plurality of LED groups connected to an output terminal of the DC/DC converter; a current source circuit unit including a plurality of current sources; a voltage detection unit detecting the output DC voltage of the DC/DC converter; a minimum voltage detection unit detecting a minimum voltage among a plurality of voltages between the plurality of LED groups and the plurality of current sources, respectively; and a single comparator including a first non-inverting input terminal receiving the voltage detected by the voltage detection unit, a second non-inverting input terminal receiving the minimum voltage detected by the minimum voltage detection unit, and an inverting input terminal receiving a predetermined reference voltage.
摘要翻译：提供了一种发光装置的驱动电路。发光的驱动电路可以包括：将输入DC电压转换为输出DC电压的DC / DC转换器; 发光器件块，包括连接到DC / DC转换器的输出端子的多个LED组; 包括多个电流源的电流源电路单元; 电压检测单元，检测DC / DC转换器的输出直流电压; 最小电压检测单元，分别检测所述多个LED组和所述多个电流源之间的多个电压中的最小电压; 以及单个比较器，包括接收由电压检测单元检测到的电压的第一非反相输入端子，接收由最小电压检测单元检测到的最小电压的第二非反相输入端子和接收预定参考值的反相输入端子电压。

16. 发明授权

US06981644B2 Apparatus and method for recognizing code 有权
标题翻译：用于识别代码的装置和方法
公开(公告)号：US06981644B2
公开(公告)日：2006-01-03
申请号：US10492305
申请日：2002-05-13
申请人： Cheol Ho Cheong , Nam Kyu Lee , Tack Don Han
发明人： Cheol Ho Cheong , Nam Kyu Lee , Tack Don Han
IPC分类号： G06K7/10
CPC分类号： G06T1/0021
摘要： An apparatus and method for recognizing a code from a code image that is expressed physically or electronically and extracting data represented in the code image is provided. The method includes the steps of receiving a raw image in which a code image is contained, detecting a background image included in the raw image, extracting a code image region in which a background image is excluded, recognizing the shape and type of the code image and the color or shade represented in each of cells, converting the color or shade recognized from each of the cells into a corresponding character, number, or symbol and generating code data. The code image in which predetermined data are represented as colors or shades are received, and original colors or shades can be precisely discriminated regardless of an environment in which the code image is recognized.
摘要翻译：提供一种用于从物理或电子表示的代码图像中识别代码并提取代码图像中表示的数据的装置和方法。该方法包括以下步骤：接收包含代码图像的原始图像，检测原始图像中包括的背景图像，提取其中排除背景图像的代码图像区域，识别代码图像的形状和类型以及在每个单元格中表示的颜色或阴影，将从每个单元识别的颜色或阴影转换为相应的字符，数字或符号并生成代码数据。接收预定数据被表示为颜色或阴影的代码图像，并且无论识别代码图像的环境如何，都可以精确地识别原始颜色或阴影。

17. 发明授权

US06693609B2 Method of generating optimal pattern of light emission and method of measuring contour noise and method of selecting gray scale for plasma display panel 失效
标题翻译：产生最佳发光模式的方法和轮廓噪声测量方法等离子显示面板灰度选择方法
公开(公告)号：US06693609B2
公开(公告)日：2004-02-17
申请号：US10001926
申请日：2001-12-05
申请人： Nam Kyu Lee , Bon Cheol Koo , Ki Sang Hong , Jae Woo Kim , Yong Duek Kim , Seong Ho Kang
发明人： Nam Kyu Lee , Bon Cheol Koo , Ki Sang Hong , Jae Woo Kim , Yong Duek Kim , Seong Ho Kang
IPC分类号： G09G328
CPC分类号： G09G3/2059 , G09G3/2029 , G09G3/288 , G09G2320/0261 , G09G2320/0266
摘要： An optimal light-emission pattern generation method for a plasma display panel according to an embodiment of the present invention includes steps of determining a plurality of light-emission patterns with respect to an arbitrary gray level; calculating a contour noise degree between a contour noise free gray level being set in advance and the light-emission patterns given to each gray level in plurality; and selecting a light-emission pattern whose contour noise degree is minimal as a light-emission pattern with respect to an arbitrary gray level.
摘要翻译：根据本发明的实施例的用于等离子体显示面板的最佳发光图案生成方法包括以下步骤：相对于任意灰度级确定多个发光图案; 计算预先设定的轮廓无噪声灰度级与给出多个灰度级的发光图案之间的轮廓噪声度; 并且选择其轮廓噪声程度最小的发光图案作为相对于任意灰度级的发光图案。

18. 发明授权

US08048912B2 Benzopyran derivatives having inhibitory activities against liver fibrosis and cirrhosis and their pharmaceutical uses 有权
标题翻译：具有对肝纤维化和肝硬化的抑制活性的苯并吡喃衍生物及其药物用途
公开(公告)号：US08048912B2
公开(公告)日：2011-11-01
申请号：US11794564
申请日：2005-06-15
申请人： Young-Dae Gong , Jin-Soo Seo , Moon-Kook Jeon , Wie-Jong Kwak , Yong-Baik Cho , Nam Kyu Lee , Eun Ju Lee , Jung Bum Lee , Jun Won Lee , Sukho Lee , Mi-Sook Dong , Jeong-Ran Kim
发明人： Young-Dae Gong , Jin-Soo Seo , Moon-Kook Jeon , Wie-Jong Kwak , Yong-Baik Cho , Nam Kyu Lee , Eun Ju Lee , Jung Bum Lee , Jun Won Lee , Sukho Lee , Mi-Sook Dong , Jeong-Ran Kim
IPC分类号： A61K31/352 , C07D311/60 , C07D311/70
CPC分类号： C07D311/70
摘要： The present invention relates to a novel benzopyran derivative having goodantagonistic activity on TGF-β receptor which can be effectively used as a prophylactic and therapeutic agent for liver disease as well as several fibroplasiadiseases such as hepatic fibrosis, liver cirrhosis, pulmonary fibrosis, dermatosclerosis, glomerular fibrosis and the like; and a pharmaceutical use thereof.
摘要翻译：本发明涉及一种对TGF-βb具有优异活性的新型苯并吡喃衍生物。受体，其可以有效地用作肝脏疾病的预防和治疗剂以及若干纤维平滑酶如肝纤维化，肝硬化，肺纤维化，皮肤硬化，肾小球纤维化等; 及其药物用途。

19. 发明授权

US07605808B2 Energy recovery apparatus and method for plasma display panel 失效
标题翻译：等离子显示面板的能量回收装置及方法
公开(公告)号：US07605808B2
公开(公告)日：2009-10-20
申请号：US10942052
申请日：2004-09-16
申请人： Nam Kyu Lee , Bong Gyun Kim , Bong Hwan Kwon , Jang Hwan Cho
发明人： Nam Kyu Lee , Bong Gyun Kim , Bong Hwan Kwon , Jang Hwan Cho
IPC分类号： G09G5/00
CPC分类号： G09G3/2965
摘要： Disclosed are an energy recovery apparatus and method for a plasma display panel. The energy recovery apparatus includes a sustain voltage source for supplying a sustain voltage, a panel capacitor formed equivalently at a discharge cell, a first charging circuit for forming a first charging path when one side of the panel capacitor is charged, a second charging circuit for forming a second charging path when the other side of the panel capacitor is charged, a first power circuit for supplying the sustain voltage to the panel capacitor and forming the first charging path, and a second power circuit for supplying a ground voltage generated from a ground voltage source to the panel capacitor and forming the second charging path. The energy recovery apparatus and method according to the present invention can decrease components in number and reduce power consumption and manufacturing cost by charging the other side of the panel capacitor using a charging voltage of one side of the panel capacitor.
摘要翻译：公开了一种用于等离子体显示面板的能量回收装置和方法。能量回收装置包括用于提供维持电压的维持电压源，在放电单元等效地形成的面板电容器，用于在面板电容器的一侧被充电时形成第一充电路径的第一充电电路;第二充电电路，当面板电容器的另一侧被充电时，形成第二充电路径，用于向面板电容器提供维持电压并形成第一充电路径的第一电源电路和用于提供从地面产生的接地电压的第二电源电路电压源到面板电容器并形成第二充电路径。根据本发明的能量回收装置和方法可以通过面板电容器的一侧的充电电压对面板电容器的另一侧进行充电来减少数量的部件并降低功耗和制造成本。

20. 发明授权

US06288693B1 Plasma display panel driving method 失效
标题翻译：等离子显示面板驱动方式
公开(公告)号：US06288693B1
公开(公告)日：2001-09-11
申请号：US08980965
申请日：1997-12-01
申请人： Young-Bok Song , Sang Jin Yun , Byeong Cheol Kim , Sung Wook Jung , Bong Koo Kang , Young Hwan Kim , Nam Kyu Lee
发明人： Young-Bok Song , Sang Jin Yun , Byeong Cheol Kim , Sung Wook Jung , Bong Koo Kang , Young Hwan Kim , Nam Kyu Lee
IPC分类号： G09G328
CPC分类号： G09G3/2927 , G09G3/293 , G09G3/294 , G09G3/2948 , G09G2310/0216 , G09G2310/0218
摘要： Provided is a method of driving a plasma display panel, which is a sub-field driving method for the plasma display panel with scan and addressing drive signals, including the steps of: a) dividing scan lines of a field into at least two areas, and scanning the areas; b) displaying a sub-field by applying different address pulses to the respective areas during the scanning; and c) repeating the preceding steps to drive the sub-field, thereby displaying the field.
摘要翻译：提供了一种驱动等离子体显示面板的方法，其是具有扫描和寻址驱动信号的等离子体显示面板的子场驱动方法，包括以下步骤：a）将场的扫描线分成至少两个区域，并扫描地区; b）通过在扫描期间向各个区域应用不同的寻址脉冲来显示子场; 以及c）重复前述步骤以驱动所述子场，从而显示所述场。

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