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11. 发明申请

US20130341274A1 MEMBRANE SEPARATION DEVICES, SYSTEMS AND METHODS EMPLOYING SAME, AND DATA MANAGEMENT SYSTEMS AND METHODS 有权
标题翻译：膜分离装置，系统和使用方法以及数据管理系统和方法
公开(公告)号：US20130341274A1
公开(公告)日：2013-12-26
申请号：US14003290
申请日：2012-03-09
申请人： Benjamin E. Kusters , Christopher J. Wegener , Daniel R. Boggs , Kyungyoon Min
发明人： Benjamin E. Kusters , Christopher J. Wegener , Daniel R. Boggs , Kyungyoon Min
IPC分类号： A61M1/34
CPC分类号： A61M1/34 , A61M1/0272 , A61M1/0281 , A61M1/265 , A61M1/3403 , A61M1/3496 , A61M1/3633 , A61M1/3687 , A61M1/3692 , A61M1/38 , A61M2205/3331 , A61M2205/50 , A61M2205/60 , B01D61/18 , B01D63/06 , B01D63/16 , B01D2313/08 , B01D2313/20 , B01D2315/02 , G16H10/40
摘要： A membrane separation device is disclosed along with systems and methods employing the device in blood processing procedures. In one embodiment, a spinning membrane separator is provided in which at least two zones or regions are created in the gap between the membrane and the shell, such that mixing of the fluid between the two regions is inhibited by a radial rib associated with the membrane that decreases the gap between the membrane and the shell to define two fluid regions, the ridge isolating the fluid in the two regions to minimize mixing between the two. Automated systems and methods are disclosed for separating a unit of previously collected whole blood into components, such as concentrated red cells and plasma, for collecting red cells and plasma directly from a donor in a single pass, and for cell washing. Data management systems and methods and priming methods are also disclosed.
摘要翻译：公开了膜分离装置以及在血液处理程序中采用该装置的系统和方法。在一个实施例中，提供了一种纺丝膜分离器，其中在膜和壳体之间的间隙中产生至少两个区域或区域，使得两个区域之间的流体的混合被与膜相关联的径向肋这减小了膜和壳体之间的间隙以限定两个流体区域，脊部分离两个区域中的流体以最小化两者之间的混合。公开了自动化系统和方法，用于将先前收集的全血的单元分离成诸如浓红细胞和血浆的组分，用于在单次通过中从供体直接收集红细胞和血浆，以及用于细胞洗涤。还公开了数据管理系统和方法以及启动方法。

12. 发明授权

US09603986B2 Device and method for processing and producing autologous platelet-rich plasma 有权
公开(公告)号：US09603986B2
公开(公告)日：2017-03-28
申请号：US14014542
申请日：2013-08-30
申请人： Benjamin E. Kusters , Christopher J. Wegener , Kyungyoon Min
发明人： Benjamin E. Kusters , Christopher J. Wegener , Kyungyoon Min
IPC分类号： B01D63/16 , A61M1/34 , A61M1/26 , A61M1/02
CPC分类号： A61M1/3496 , A61M1/0218 , A61M1/265 , A61M2205/103 , A61M2205/75 , B01D63/16 , B01D2317/02 , B01D2319/02 , B01D2319/06
摘要： A system and method are provided, including an integrated single-use kit, for processing whole blood to produce platelet rich plasma. A two stage spinning membrane separator, has a first stage for receiving whole blood and separating substantially all red blood cells from plasma and platelets, and a second stage for further separating platelet rich plasma from plasma. A first waste container is in fluid communication with the first stage of the separator for receiving separated red blood cells, while a second waste container is in fluid communication with the second stage of the separator for receiving separated plasma. An outlet line is in fluid communication with the second stage of the separator for receiving platelet rich plasma, and a reinfusion container is removably connected to the outlet line for receiving platelet rich plasma from the second stage of the separator.

13. 发明申请

US20130341275A1 MEMBRANE SEPARATION DEVICES, SYSTEMS AND METHODS EMPLOYING SAME, AND DATA MANAGEMENT SYSTEMS AND METHODS 有权
公开(公告)号：US20130341275A1
公开(公告)日：2013-12-26
申请号：US14003298
申请日：2012-03-09
申请人： Benjamin E. Kusters , Christopher J. Wegener , Kyungyoon Min
发明人： Benjamin E. Kusters , Christopher J. Wegener , Kyungyoon Min
IPC分类号： A61M1/34
CPC分类号： A61M1/34 , A61M1/0272 , A61M1/0281 , A61M1/265 , A61M1/3403 , A61M1/3496 , A61M1/3633 , A61M1/3687 , A61M1/3692 , A61M1/38 , A61M2205/3331 , A61M2205/50 , A61M2205/60 , B01D61/18 , B01D63/06 , B01D63/16 , B01D2313/08 , B01D2313/20 , B01D2315/02 , G16H10/40
摘要： A membrane separation device is disclosed along with systems and methods employing the device in blood processing procedures. In one embodiment, a spinning membrane separator is provided in which at least two zones or regions are created in the gap between the membrane and the shell, such that mixing of the fluid between the two regions is inhibited by a radial rib associated with the membrane that decreases the gap between the membrane and the shell to define two fluid regions, the ridge isolating the fluid in the two regions to minimize mixing between the two. Automated systems and methods are disclosed for separating a unit of previously collected whole blood into components, such as concentrated red cells and plasma, for collecting red cells and plasma directly from a donor in a single pass, and for cell washing. Data management systems and methods and priming methods are also disclosed.

14. 发明授权

US09895482B2 Membrane separation devices, systems and methods employing same, and data management systems and methods 有权
公开(公告)号：US09895482B2
公开(公告)日：2018-02-20
申请号：US14003298
申请日：2012-03-09
申请人： Benjamin E. Kusters , Christopher J. Wegener , Kyungyoon Min
发明人： Benjamin E. Kusters , Christopher J. Wegener , Kyungyoon Min
IPC分类号： A61M1/34 , A61M1/36 , A61M1/02 , B01D61/18 , B01D63/06 , B01D63/16 , A61M1/38 , A61M1/26 , B01D33/06 , G06F19/00
CPC分类号： A61M1/34 , A61M1/0272 , A61M1/0281 , A61M1/265 , A61M1/3403 , A61M1/3496 , A61M1/3633 , A61M1/3687 , A61M1/3692 , A61M1/38 , A61M2205/3331 , A61M2205/50 , A61M2205/60 , B01D61/18 , B01D63/06 , B01D63/16 , B01D2313/08 , B01D2313/20 , B01D2315/02 , G16H10/40
摘要： A membrane separation device is disclosed along with systems and methods employing the device in blood processing procedures. In one embodiment, a spinning membrane separator is provided in which at least two zones or regions are created in the gap between the membrane and the shell, such that mixing of the fluid between the two regions is inhibited by a radial rib associated with the membrane that decreases the gap between the membrane and the shell to define two fluid regions, the ridge isolating the fluid in the two regions to minimize mixing between the two. Automated systems and methods are disclosed for separating a unit of previously collected whole blood into components, such as concentrated red cells and plasma, for collecting red cells and plasma directly from a donor in a single pass, and for cell washing. Data management systems and methods and priming methods are also disclosed.

15. 发明申请

US20150060363A1 DEVICE AND METHOD FOR PROCESSING AND PRODUCING AUTOLOGOUS PLATELET-RICH PLASMA 有权
标题翻译：用于处理和生产自动化等离子体的装置和方法
公开(公告)号：US20150060363A1
公开(公告)日：2015-03-05
申请号：US14014542
申请日：2013-08-30
申请人： Benjamin E. Kusters , Christopher J. Wegener , Kyungyoon Min
发明人： Benjamin E. Kusters , Christopher J. Wegener , Kyungyoon Min
IPC分类号： A61M1/34
CPC分类号： A61M1/3496 , A61M1/0218 , A61M1/265 , A61M2205/103 , A61M2205/75 , B01D63/16 , B01D2317/02 , B01D2319/02 , B01D2319/06
摘要： A system and method are provided, including an integrated single-use kit, for processing whole blood to produce platelet rich plasma. A two stage spinning membrane separator, has a first stage for receiving whole blood and separating substantially all red blood cells from plasma and platelets, and a second stage for further separating platelet rich plasma from plasma. A first waste container is in fluid communication with the first stage of the separator for receiving separated red blood cells, while a second waste container is in fluid communication with the second stage of the separator for receiving separated plasma. An outlet line is in fluid communication with the second stage of the separator for receiving platelet rich plasma, and a reinfusion container is removably connected to the outlet line for receiving platelet rich plasma from the second stage of the separator.
摘要翻译：提供了一种系统和方法，包括一体化的一次性使用试剂盒，用于处理全血以产生富血小板血浆。两级纺丝膜分离器具有第一阶段，用于接收全血并将血浆和血小板基本上全部红细胞分离，以及用于从血浆中进一步分离富血小板血浆的第二阶段。第一废物容器与分离器的第一级流体连通，用于接收分离的红细胞，而第二废物容器与分离器的第二级流体连通以接收分离的等离子体。出口管线与分离器的第二级流体连通，用于接收富血小板血浆，并且再输注容器可移除地连接到出口管线，用于从分离器的第二级接收富血小板血浆。

16. 发明授权

US09533089B2 Centrifugation system with red blood cell barrier 有权
标题翻译：具有红细胞屏障的离心系统
公开(公告)号：US09533089B2
公开(公告)日：2017-01-03
申请号：US14008651
申请日：2012-03-28
申请人： Kyungyoon Min , Richard I. Brown , John T. Foley , Brian C. Case
发明人： Kyungyoon Min , Richard I. Brown , John T. Foley , Brian C. Case
IPC分类号： A61M1/36 , B04B5/04
CPC分类号： A61M1/3693 , A61M1/3696 , A61M2205/128 , A61M2205/3331 , A61M2205/3337 , B04B5/0442 , B04B2005/045 , C12N5/0634 , C12N5/0641 , C12N5/0644
摘要： Centrifugation systems and methods are provided for separating blood into its constituent parts. Inner and outer walls of a centrifuge each include a projection which extends toward the other wall. A separation chamber is received in the centrifuge between the walls, with the chamber including an inlet port for flowing blood into the chamber, a plasma outlet port for flowing plasma out of the chamber, and a red cell outlet port for flowing red blood cells out of the chamber. With the chamber received in the centrifuge between the walls, the first projection extends into the path of separated blood components flowing toward the plasma outlet port and prevents cellular blood components from flowing into the plasma outlet port. The second projection extends into the path of separated blood components flowing toward the red cell outlet port and prevents plasma from flowing into the red cell outlet port.
摘要翻译：提供离心系统和方法用于将血液分离成其组成部分。离心机的内壁和外壁各自包括朝向另一壁延伸的突起。分离室被容纳在离心机之间的壁之间，其中腔室包括用于使血液进入腔室的入口端口，用于使等离子体流出腔室的等离子体出口和用于使红细胞流出的红细胞出口的房间。随着室中的离心机容纳在壁之间，第一突出部延伸到分离的血液成分流向等离子体出口端口的路径中，并防止细胞血液成分流入等离子体出口。第二突出部延伸到朝向红细胞出口流动的分离的血液成分的路径中，并防止血浆流入红细胞出口。

17. 发明授权

US09131268B2 Display device, display method, and multimedia transmission method 有权
标题翻译：显示设备，显示方式和多媒体传输方式
公开(公告)号：US09131268B2
公开(公告)日：2015-09-08
申请号：US13643734
申请日：2011-09-28
申请人： Kyungyoon Min
发明人： Kyungyoon Min
IPC分类号： G06F3/038 , G09G5/00 , H04N21/4363 , H04N5/765 , G06F3/14
CPC分类号： H04N21/43635 , G06F3/1446 , G09G5/006 , G09G2358/00 , G09G2370/04 , G09G2370/10 , G09G2370/12 , H04N5/765
摘要： Provided are a display device configuring a multi-display and a display method. The multi-media display receives a DisplayPort signal from outside, converts the received signal into a set of LVTTL signals, converts a portion of the LVTTL signals into a high-quality image signal capable of using HDMI to display multimedia on a corresponding display device, and converts another portion of the LVTTL signals into a DisplayPort signal to transmit the DisplayPort signal to another display device. Accordingly, an infinite multi-display can display high quality multimedia.
摘要翻译：提供了构成多显示器和显示方法的显示装置。多媒体显示器从外部接收DisplayPort信号，将接收到的信号转换为一组LVTTL信号，将一部分LVTTL信号转换为能够使用HDMI在相应显示装置上显示多媒体的高质量图像信号，并将LVTTL信号的另一部分转换成DisplayPort信号，以将DisplayPort信号传输到另一显示设备。因此，无限多显示器可以显示高质量的多媒体。

18. 发明申请

US20140045671A1 CENTRIFUGATION SYSTEM WITH RED BLOOD CELL BARRIER 有权
标题翻译：红血球细胞分离系统
公开(公告)号：US20140045671A1
公开(公告)日：2014-02-13
申请号：US14008651
申请日：2012-03-28
申请人： Kyungyoon Min , Richard I. Brown , John T. Foley , Brian C. Case
发明人： Kyungyoon Min , Richard I. Brown , John T. Foley , Brian C. Case
IPC分类号： A61M1/36
CPC分类号： A61M1/3693 , A61M1/3696 , A61M2205/128 , A61M2205/3331 , A61M2205/3337 , B04B5/0442 , B04B2005/045 , C12N5/0634 , C12N5/0641 , C12N5/0644
摘要： Centrifugation systems and methods are provided for separating blood into its constituent parts. Inner and outer walls of a centrifuge each include a projection which extends toward the other wall. A separation chamber is received in the centrifuge between the walls, with the chamber including an inlet port for flowing blood into the chamber, a plasma outlet port for flowing plasma out of the chamber, and a red cell outlet port for flowing red blood cells out of the chamber. With the chamber received in the centrifuge between the walls, the first projection extends into the path of separated blood components flowing toward the plasma outlet port and prevents cellular blood components from flowing into the plasma outlet port. The second projection extends into the path of separated blood components flowing toward the red cell outlet port and prevents plasma from flowing into the red cell outlet port.
摘要翻译：提供离心系统和方法用于将血液分离成其组成部分。离心机的内壁和外壁各自包括朝向另一壁延伸的突起。分离室被容纳在离心机之间的壁之间，其中腔室包括用于使血液进入腔室的入口端口，用于使等离子体流出腔室的等离子体出口和用于使红细胞流出的红细胞出口的房间。随着室中的离心机容纳在壁之间，第一突出部延伸到分离的血液成分流向等离子体出口端口的路径中，并防止细胞血液成分流入等离子体出口。第二突出部延伸到朝向红细胞出口流动的分离的血液成分的路径中，并防止血浆流入红细胞出口。

19. 发明申请

US20130038508A1 DISPLAY DEVICE, DISPLAY METHOD, AND MULTIMEDIA TRANSMISSION 10 METHOD 有权
标题翻译：显示设备，显示方法和多媒体传输10方法
公开(公告)号：US20130038508A1
公开(公告)日：2013-02-14
申请号：US13643734
申请日：2011-09-28
申请人： Kyungyoon Min
发明人： Kyungyoon Min
IPC分类号： G09G5/00 , G06F3/038
CPC分类号： H04N21/43635 , G06F3/1446 , G09G5/006 , G09G2358/00 , G09G2370/04 , G09G2370/10 , G09G2370/12 , H04N5/765
摘要： Provided are a display device configuring a multi-display and a display method. The multi-media display receives a DisplayPort signal from outside, converts the received signal into a set of LVTTL signals, converts a portion of the LVTTL signals into a high-quality image signal capable of using HDMI to display multimedia on a corresponding display device, and converts another portion of the LVTTL signals into a DisplayPort signal to transmit the DisplayPort signal to another display device. Accordingly, an infinite multi-display can display high quality multimedia.
摘要翻译：提供了构成多显示器和显示方法的显示装置。多媒体显示器从外部接收DisplayPort信号，将接收到的信号转换为一组LVTTL信号，将一部分LVTTL信号转换为能够使用HDMI在相应显示装置上显示多媒体的高质量图像信号，并将LVTTL信号的另一部分转换成DisplayPort信号，以将DisplayPort信号传输到另一显示设备。因此，无限多显示器可以显示高质量的多媒体。

20. 发明授权

US08075468B2 Systems and methods for mid-processing calculation of blood composition 有权
标题翻译：血液成分中期计算的系统和方法
公开(公告)号：US08075468B2
公开(公告)日：2011-12-13
申请号：US12394375
申请日：2009-02-27
申请人： Kyungyoon Min , Richard I. Brown
发明人： Kyungyoon Min , Richard I. Brown
IPC分类号： B01D21/26 , B04B3/00
CPC分类号： A61M1/3693 , A61M1/0209 , A61M1/3696 , A61M2205/3306 , B01D21/262 , B01D21/302 , B01D21/34 , B01D2221/08 , B01D2221/10
摘要： Blood separation methods are provided for mid-processing calculation of blood composition. Blood is conveyed into a device having an outlet line and the device is spun to separate platelets from the blood. A flow of platelets is conveyed from the device by the outlet line and the platelets in the outlet line are optically measured. With said optical measurement, a current platelet yield, a platelet pre-count, the volume of blood to process to collect a target amount of platelets, and/or the processing time required to collect a target amount of platelets is calculated. The optical measurement can also be used to calculate an amount of storage fluid to convey into a collection container with the platelets.
摘要翻译：提供血液分离方法用于血液成分的中间处理计算。将血液输送到具有出口管线的装置中，并且将该装置旋转以将血小板与血液分开。通过出口管线从装置输送血小板流，并且光学测量出口管线中的血小板。通过所述光学测量，计算目前的血小板产量，血小板预计数，用于收集目标量的血小板的血液的体积和/或收集目标量的血小板所需的处理时间。光学测量还可用于计算与血小板一起输送到收集容器中的储存液体的量。

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