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11. 发明申请

US20140051977A9 Optimal Respiratory Gating In Medical Imaging 有权
标题翻译：医学影像中的最佳呼吸门控
公开(公告)号：US20140051977A9
公开(公告)日：2014-02-20
申请号：US13248089
申请日：2011-09-29
申请人： James J. Hamill , Ludovic Le Meunier
发明人： James J. Hamill , Ludovic Le Meunier
IPC分类号： A61B5/055 , A61B5/05
CPC分类号： A61B5/7292 , A61B5/1135 , A61B6/037 , A61B6/541 , G01R33/481 , G01R33/5676
摘要： Methods and computer-readable mediums are provided for obtaining an optimally gated medical image. For example, in one embodiment, a method is provided that acquires medical images in list mode. The method also acquires a respiration correlated signal S(t). Thereafter, a final upper strain threshold value and a final lower strain threshold value pair that has a narrowest interval are selected. The medical images are synchronized with the respiration correlated signal S(t). The synchronized images and signal are used to create an optimally gated medical image. In various embodiments, the disclosed optimal gating can be utilized in PET systems and in other embodiments the disclosed optimal gating can be utilized in SPECT systems. In yet other embodiments, the optimally gated images can be matched to MRI systems and in still other embodiments, the optimally gated images can be matched to CT systems.
摘要翻译：提供方法和计算机可读介质以获得最佳门控的医学图像。例如，在一个实施例中，提供了以列表模式获取医学图像的方法。该方法还获取呼吸相关信号S（t）。此后，选择具有最窄间隔的最终上应变阈值和最终下应变阈值对。医学图像与呼吸相关信号S（t）同步。同步的图像和信号用于创建最佳门控的医学图像。在各种实施例中，所公开的最佳选通可用于PET系统中，并且在其它实施例中，所公开的最佳门控可用于SPECT系统。在其他实施例中，最佳门控图像可以与MRI系统匹配，并且在其他实施例中，最佳门控图像可以与CT系统匹配。

12. 发明申请

US20120069946A1 Compact Radioisotope Generator 审中-公开
标题翻译：紧凑型放射性同位素发生器
公开(公告)号：US20120069946A1
公开(公告)日：2012-03-22
申请号：US12887933
申请日：2010-09-22
申请人： James J. Hamill , Stefan B. Siegel , Charles Russell Buchanan
发明人： James J. Hamill , Stefan B. Siegel , Charles Russell Buchanan
IPC分类号： G21G1/06
CPC分类号： G21G1/06 , G21G2001/0094
摘要： Disclosed are a method and apparatus for making a radioisotope and a composition of matter including the radioisotope. The radioisotope is made by exposing a material to neutrons from a portable neutron source.
摘要翻译：公开了制备放射性同位素的方法和装置以及包括放射性同位素的物质组成。放射性同位素是通过将材料从便携式中子源暴露于中子而制成的。

13. 发明授权

US10186337B2 Compact radioisotope generator 有权
公开(公告)号：US10186337B2
公开(公告)日：2019-01-22
申请号：US12887933
申请日：2010-09-22
申请人： James J. Hamill , Stefan B. Siegel , Charles Russell Buchanan
发明人： James J. Hamill , Stefan B. Siegel , Charles Russell Buchanan
IPC分类号： G21G1/06 , G21G1/00
摘要： A method and apparatus for making a radioisotope and a composition of matter including the radioisotope. The radioisotope is made by exposing a material to neutrons from a portable neutron source. More specifically, a solution includes a particular isotope. The neutron source is completely surrounded by the solution. The solution is exposed to the neutrons. Generated radioisotopes are extracted from the solution.

14. 发明授权

US09456791B2 System and method for constraining a computerized tomography patient 有权
标题翻译：用于约束计算机断层摄影患者的系统和方法
公开(公告)号：US09456791B2
公开(公告)日：2016-10-04
申请号：US12558159
申请日：2009-09-11
申请人： James J. Hamill , Carl Eric Arnsdorff
发明人： James J. Hamill , Carl Eric Arnsdorff
IPC分类号： A61G15/00 , A61B6/03 , A61B6/04 , A61B5/103 , A61B6/00
CPC分类号： A61B6/037 , A61B5/103 , A61B6/0421 , A61B6/482
摘要： A constraint having a main body and at least one coupler. The main body can be substantially arcuate in shape and can be configured to constrain a patient. The at least one coupler can couple the main body to a bed or treatment pallet. The constraint can be sized to restrict a patient within a computerized tomography (CT) scan field of view.
摘要翻译：具有主体和至少一个耦合器的约束。主体可以是基本上弓形的形状，并且可以构造成约束患者。所述至少一个联接器可以将主体连接到床或处理托盘。该约束的大小可以限制在计算机断层摄影（CT）扫描视野内的患者。

15. 发明授权

US07769217B2 Fast iterative 3D PET image reconstruction using a set of 2D linogram transformations 失效
标题翻译：快速迭代3D PET图像重建使用一组二维线条图变换
公开(公告)号：US07769217B2
公开(公告)日：2010-08-03
申请号：US11714406
申请日：2007-03-06
申请人： James J. Hamill
发明人： James J. Hamill
IPC分类号： G06K9/00
CPC分类号： G06T11/006 , G06T2211/424
摘要： A method for performing accurate iterative reconstruction of three dimensional image data sets based on Approximate Discrete Radon Transformation (ADRT) using two dimensional linograms for each of a plurality of defined planes tilted from the (x, y, 0) plane by a tilt angle and orientation angle. Image data is arranged with respect to the defined tilted planes ADRT and its inverse are implemented to provide exactly matched forward and backward projectors suitable for the Maximum-Likelihood Expectation-Maximization (ML-EM) reconstruction in PET. An EM reconstruction algorithm is accomplished by initializing an estimation image.
摘要翻译：一种用于基于近似离散氡变换（ADRT）对三维图像数据集进行精确迭代重建的方法，所述方法使用用于从（x，y，0）平面倾斜倾斜角度的多个限定平面中的每一个定义的平面使用二维立体图，取向角度。图像数据相对于定义的倾斜平面ADRT布置，并且其反向被实现以提供适合于PET中的最大似然期望最大化（ML-EM）重建的精确匹配的前向和后向投影仪。通过初始化估计图像来实现EM重建算法。

16. 发明授权

US07483518B2 Apparatus and method for rapidly switching the energy spectrum of diagnostic X-ray beams 失效
标题翻译：用于快速切换诊断X射线束的能谱的装置和方法
公开(公告)号：US07483518B2
公开(公告)日：2009-01-27
申请号：US11519410
申请日：2006-09-12
申请人： James J. Hamill
发明人： James J. Hamill
IPC分类号： H01J35/10 , H01J35/00 , G21K3/00
CPC分类号： H01J35/18 , G21K1/10 , H01J35/305 , H01J2235/183
摘要： An X-ray imaging apparatus is disclosed. The apparatus includes a radiator housing, an X-ray tube, a source of X-rays and at least one filtration material disposed on the X-ray tube. The X-ray tube is rotatable about a longitudinal axis and is disposed at least partially within the radiator housing. The source of X-rays emits at least one X-ray beam at least partially through the X-ray tube. The X-ray beam exits the X-ray tube at an annular X-ray window. The filtration material at least partially covers a portion of the annular X-ray window. Rotation of the X-ray tube causes the X-ray beam to pass through a plurality of locations in the annular X-ray window and at least a portion of the X-ray beam is filtered by the filtration material.
摘要翻译：公开了一种X射线成像装置。该装置包括散热器壳体，X射线管，X射线源和设置在X射线管上的至少一个过滤材料。 X射线管可以围绕纵向轴线旋转并且至少部分地设置在散热器壳体内。 X射线源至少部分地通过X射线管发射至少一个X射线束。 X射线束以环形X射线窗口离开X射线管。过滤材料至少部分地覆盖环形X射线窗口的一部分。 X射线管的旋转导致X射线束穿过环形X射线窗口中的多个位置，X射线束的至少一部分被过滤材料过滤。

17. 发明申请

US20080063145A1 Apparatus and method for rapidly switching the energy spectrum of diagnostic X-ray beams 失效
标题翻译：用于快速切换诊断X射线束的能谱的装置和方法
公开(公告)号：US20080063145A1
公开(公告)日：2008-03-13
申请号：US11519410
申请日：2006-09-12
申请人： James J. Hamill
发明人： James J. Hamill
IPC分类号： H01J35/10
CPC分类号： H01J35/18 , G21K1/10 , H01J35/305 , H01J2235/183
摘要： An X-ray imaging apparatus is disclosed. The apparatus includes a radiator housing, an X-ray tube, a source of X-rays and at least one filtration material disposed on the X-ray tube. The X-ray tube is rotatable about a longitudinal axis and is disposed at least partially within the radiator housing. The source of X-rays emits at least one X-ray beam at least partially through the X-ray tube. The X-ray beam exits the X-ray tube at an annular X-ray window. The filtration material at least partially covers a portion of the annular X-ray window. Rotation of the X-ray tube causes the X-ray beam to pass through a plurality of locations in the annular X-ray window and at least a portion of the X-ray beam is filtered by the filtration material.
摘要翻译：公开了一种X射线成像装置。该装置包括散热器壳体，X射线管，X射线源和设置在X射线管上的至少一个过滤材料。 X射线管可以围绕纵向轴线旋转并且至少部分地设置在散热器壳体内。 X射线源至少部分地通过X射线管发射至少一个X射线束。 X射线束以环形X射线窗口离开X射线管。过滤材料至少部分地覆盖环形X射线窗口的一部分。 X射线管的旋转导致X射线束穿过环形X射线窗口中的多个位置，X射线束的至少一部分被过滤材料过滤。

18. 发明授权

US09579070B2 Optimal respiratory gating in medical imaging 有权
标题翻译：医学成像中的最佳呼吸门控
公开(公告)号：US09579070B2
公开(公告)日：2017-02-28
申请号：US13248089
申请日：2011-09-29
申请人： James J. Hamill , Ludovic Le Meunier
发明人： James J. Hamill , Ludovic Le Meunier
IPC分类号： A61B5/00 , A61B6/00 , A61B5/113 , A61B6/03 , G01R33/48 , G01R33/567
CPC分类号： A61B5/7292 , A61B5/1135 , A61B6/037 , A61B6/541 , G01R33/481 , G01R33/5676
摘要： Methods and computer-readable mediums are provided for obtaining an optimally gated medical image. For example, in one embodiment, a method is provided that acquires medical images in list mode. The method also acquires a respiration correlated signal S(t). Thereafter, a final upper strain threshold value and a final lower strain threshold value pair that has a narrowest interval are selected. The medical images are synchronized with the respiration correlated signal S(t). The synchronized images and signal are used to create an optimally gated medical image. In various embodiments, the disclosed optimal gating can be utilized in PET systems and in other embodiments the disclosed optimal gating can be utilized in SPECT systems. In yet other embodiments, the optimally gated images can be matched to MRI systems and in still other embodiments, the optimally gated images can be matched to CT systems.
摘要翻译：提供方法和计算机可读介质以获得最佳门控的医学图像。例如，在一个实施例中，提供了以列表模式获取医学图像的方法。该方法还获取呼吸相关信号S（t）。此后，选择具有最窄间隔的最终上应变阈值和最终下应变阈值对。医学图像与呼吸相关信号S（t）同步。同步的图像和信号用于创建最佳门控的医学图像。在各种实施例中，所公开的最佳选通可用于PET系统中，并且在其它实施例中，所公开的最佳门控可用于SPECT系统。在其他实施例中，最佳门控图像可以与MRI系统匹配，并且在其他实施例中，最佳门控图像可以与CT系统匹配。

19. 发明申请

US20130085375A1 Optimal Respiratory Gating In Medical Imaging 有权
标题翻译：医学影像中的最佳呼吸门控
公开(公告)号：US20130085375A1
公开(公告)日：2013-04-04
申请号：US13248089
申请日：2011-09-29
申请人： James J. Hamill , Ludovic Le Meunier
发明人： James J. Hamill , Ludovic Le Meunier
IPC分类号： A61B5/055 , A61B5/05
CPC分类号： A61B5/7292 , A61B5/1135 , A61B6/037 , A61B6/541 , G01R33/481 , G01R33/5676
摘要： Methods and computer-readable mediums are provided for obtaining an optimally gated medical image. For example, in one embodiment, a method is provided that acquires medical images in list mode. The method also acquires a respiration correlated signal S(t). Thereafter, a final upper strain threshold value and a final lower strain threshold value pair that has a narrowest interval are selected. The medical images are synchronized with the respiration correlated signal S(t). The synchronized images and signal are used to create an optimally gated medical image. In various embodiments, the disclosed optimal gating can be utilized in PET systems and in other embodiments the disclosed optimal gating can be utilized in SPECT systems. In yet other embodiments, the optimally gated images can be matched to MRI systems and in still other embodiments, the optimally gated images can be matched to CT systems.
摘要翻译：提供方法和计算机可读介质以获得最佳门控的医学图像。例如，在一个实施例中，提供了以列表模式获取医学图像的方法。该方法还获取呼吸相关信号S（t）。此后，选择具有最窄间隔的最终上应变阈值和最终下应变阈值对。医学图像与呼吸相关信号S（t）同步。同步的图像和信号用于创建最佳门控的医学图像。在各种实施例中，所公开的最佳选通可用于PET系统中，并且在其它实施例中，所公开的最佳门控可用于SPECT系统。在其他实施例中，最佳门控图像可以与MRI系统匹配，并且在其他实施例中，最佳门控图像可以与CT系统匹配。

20. 发明授权

US08060177B2 Registration of computed tomography (CT) and positron emission tomography (PET) image scans with automatic patient motion correction 有权
标题翻译：计算机断层扫描（CT）和正电子发射断层扫描（PET）图像扫描与自动患者运动校正的注册
公开(公告)号：US08060177B2
公开(公告)日：2011-11-15
申请号：US11714405
申请日：2007-03-06
申请人： James J. Hamill
发明人： James J. Hamill
IPC分类号： A61B5/05
CPC分类号： A61B6/032 , A61B6/037 , A61B6/5235 , A61B6/541 , G01T1/1615
摘要： A method for combined computed tomography (CT) imaging and positron emission tomography (PET) imaging uses respiration-gated CT imaging in which the optimal criteria for CT scan gating are determined after the PET scan has been performed. After acquisition of first CT scan image data and PET scan image data with strain gauge levels being recorded, optimal gating criteria are calculated based on the strain gauge levels, and a second CT scan is then performed with triggering in accordance with the optimal gating criteria.
摘要翻译： CT扫描成像和正电子发射断层扫描（PET）成像的方法是使用呼吸门控CT成像，其中在执行PET扫描之后确定CT扫描门控的最佳标准。在记录了应变仪电平的第一CT扫描图像数据和PET扫描图像数据的采集之后，根据应变计电平计算最佳选通标准，然后根据最佳选通标准触发进行第二次CT扫描。

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