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11. 发明公开

EP2613829A1 METERED-DOSE INHALER AND METHOD OF USING THE SAME 有权转让
标题翻译： INHALIERGERÄTMIT ABGEMESSENER DOSIS UND VERWENDUNGSVERFAHRENDAFÜR
公开(公告)号：EP2613829A1
公开(公告)日：2013-07-17
申请号：EP11757244.6
申请日：2011-09-05
申请人： CHIESI FARMACEUTICI S.p.A.
发明人： BRAMBILLA, Gaetano , LEWIS, David Andrew , JOHNSON, Robert , HOWLETT, David
IPC分类号： A61M15/00 , A61J1/20 , B05B11/00 , B65D83/14
CPC分类号： A61M15/009 , A61J1/2037 , A61J1/2089 , A61M15/0003 , B65D83/54 , B65D83/682
摘要： A metered-dose inhaler includes at least one vessel and an actuator for receiving the at least one vessel. The at least one vessel includes a first reservoir containing a first formulation and a second reservoir containing a second formulation. The metered-dose inhaler is actuable when the at least one vessel is received by the actuator. The metered-dose inhaler is configured to simultaneously deliver a first metered dose of the first formulation and a second metered dose of the second formulation upon actuation.
摘要翻译：计量吸入器包括至少一个容器和用于容纳至少一个容器的致动器。所述至少一个容器包括含有第一制剂的第一储存器和含有第二制剂的第二储存器。当至少一个容器被致动器接收时，计量吸入器是可启动的。计量吸入器构造成在致动时同时递送第一制剂的第一计量剂量和第二制剂的第二计量剂量。

12. 发明申请

WO2007056509A1 MOLDED SHAVING AID COMPOSITIONS, COMPONENTS AND METHODE OF MANUFACTURE 审中-公开
标题翻译：模制冲击助剂组合物，组分和制造方法
公开(公告)号：WO2007056509A1
公开(公告)日：2007-05-18
申请号：PCT/US2006/043611
申请日：2006-11-09
申请人： THE GILLETTE COMPANY , O'GRADY, Janet, Kelley , WESTGATE, Marilyn, Jeanne , CORBEIL, Corey, Edward , JOHNSON, Robert , MORRISSEY, Maureen, Sullivan , YU, Yun , DANTI, Gregory, Thomas , ANDERSON, John , MOLONEY, Michael, John , HOULIHAN, Robert, Michael
发明人： O'GRADY, Janet, Kelley , WESTGATE, Marilyn, Jeanne , CORBEIL, Corey, Edward , JOHNSON, Robert , MORRISSEY, Maureen, Sullivan , YU, Yun , DANTI, Gregory, Thomas , ANDERSON, John , MOLONEY, Michael, John , HOULIHAN, Robert, Michael
IPC分类号： B26B21/44 , A61K8/89 , A61Q9/02
CPC分类号： B26B21/44 , A61K8/0204 , A61K8/361 , A61K8/8111 , A61K8/86 , A61K8/894 , A61K8/895 , A61Q9/00 , A61Q9/02 , B26B21/222 , B26B21/443
摘要： Razors and components thereof are provided, as well as methods of making such.
摘要翻译：提供了剃须刀及其部件，以及制造其的方法。

13. 发明申请

WO2007056127A1 METHOD FOR PRODUCING FLUORINATED ORGANIC COMPOUNDS 审中-公开
标题翻译：生产氟化有机化合物的方法
公开(公告)号：WO2007056127A1
公开(公告)日：2007-05-18
申请号：PCT/US2006/042935
申请日：2006-11-03
申请人： HONEYWELL INTERNATIONAL INC. , MUKHOPADHYAY, Sudip , NAIR, Haridasan , TUNG, Hsueh Sung , VAN DER PUY, Michael , JOHNSON, Robert , MERKEL, Daniel, C.
发明人： MUKHOPADHYAY, Sudip , NAIR, Haridasan , TUNG, Hsueh Sung , VAN DER PUY, Michael , JOHNSON, Robert , MERKEL, Daniel, C.
IPC分类号： C07C17/266 , C07C17/269 , C07C21/18
CPC分类号： C07C21/18 , C07C17/266 , C07C17/269
摘要： Disclosed is a process for the preparation of fluorinated C3 olefins comprising contacting a compound of the Formula (I): C(R 1 a R 2 b R 3 c ), with a compound of Formula (II) C(R 1 a R 2 b R 3 c )C n (R 1 a R 2 b R 3 c ): wherein R 1 a , R 2 b, and R 3 c are independently a hydrogen atom or a halogen selected from the group consisting of fluorine; chlorine, bromine and iodine, provided that the compound of formula (I) has at least three halogen substituents and that said at three halogen substituents comprise at least one fluorine; a, b and c are independently= 0, 1, 2 or 3 and (a+b+c) = 2 or 3; and n is 0 or 1, under conditions effective to produce at least one C3 fluoroolefin.
摘要翻译：公开了一种制备氟化C3烯烃的方法，包括使式（I）的化合物：C（R 1）

14. 发明申请

WO2005045393A2 DETERMINATION OF A MEASURE OF A GLYCATION END-PRODUCT OR DISEASE STATE USING TISSUE FLUORESCENCE 审中-公开
标题翻译：使用组织荧光测定糖果终产物或疾病状态的测量
公开(公告)号：WO2005045393A2
公开(公告)日：2005-05-19
申请号：PCT/US2004/035462
申请日：2004-10-26
申请人： INLIGHT SOLUTIONS, INC. , HULL, L., Edward , MARWOOD, Neal, Ediger , BROWN, Christopher, D. , JOHNSON, Robert
发明人： HULL, L., Edward , MARWOOD, Neal, Ediger , BROWN, Christopher, D. , JOHNSON, Robert
IPC分类号： G01N
CPC分类号： A61B5/1455 , A61B5/0059 , A61B5/0064 , A61B5/0066 , A61B5/0068 , A61B5/0071 , A61B5/0075 , A61B5/14532 , A61B5/412 , A61B5/441
摘要： A method of determining a measure of a tissue state ( e.g. , glycation end-product or disease state) in an individual. A portion of the tissue of the individual is illuminated with excitation light, then light emitted by the tissue due to fluorescence of a chemical with the tissue responsive to the excitation light is detected. The detected light can be combined with a model relating fluorescence with a measure of tissue state to determine a tissue state. The invention can comprise single wavelength excitation light, scanning of excitation light (illuminating the tissue at a plurality of wavelengths), detection at a single wavelength, scanning of detection wavelengths (detecting emitted light at a plurality of wavelengths), and combinations thereof. The invention also can comprise correction techniques that reduce determination errors due to detection of light other than that from fluorescence of a chemical in the tissue. For example, the reflectance of the tissue can lead to errors if appropriate correction is not employed. The invention can also comprise a variety of models relating fluorescence to a measure of tissue state, including a variety of methods for generating such models. Other biologic information can be used in combination with the fluorescence properties to aid in the determination of a measure of tissue state. The invention also comprises apparatuses suitable for carrying out the method, including appropriate light sources, detectors, and models (for example, implemented on computers) used to relate detected fluorescence and a measure of tissue state.
摘要翻译：确定个体中组织状态（例如，糖基化终产物或疾病状态）的量度的方法。用激发光照射个体组织的一部分，然后检测由组织响应于激发光的化学物质的荧光而由组织发出的光。检测到的光可以与将荧光与组织状态的测量相关联的模型组合以确定组织状态。本发明可以包括单波长激发光，激发光的扫描（以多个波长照射组织），单个波长的检测，检测波长的扫描（检测多个波长的发射光）及其组合。本发明还可以包括校正技术，其减少由于检测除了组织中的化学物质的荧光以外的光的测定误差。例如，如果不采用适当的校正，组织的反射率可能导致错误。本发明还可以包括将荧光与组织状态的测量相关联的各种模型，包括用于产生这种模型的各种方法。其他生物信息可与荧光性质结合使用，有助于测定组织状态。本发明还包括适于执行该方法的装置，包括用于检测荧光和组织状态测量的适当的光源，检测器和模型（例如，在计算机上实现）。

15. 发明申请

WO2007147116A2 VAGINAL DRUG DELIVERY SYSTEM AND METHOD 审中-公开
标题翻译： VAGINAL药物递送系统和方法
公开(公告)号：WO2007147116A2
公开(公告)日：2007-12-21
申请号：PCT/US2007/071347
申请日：2007-06-15
申请人： FAMILY HEALTH INTERNATIONAL , SOKAL, David , JOANIS, Carol , BUTTERWORTH, George , REED, James , JOHNSON, Robert
发明人： SOKAL, David , JOANIS, Carol , BUTTERWORTH, George , REED, James , JOHNSON, Robert
IPC分类号： A61F13/20
CPC分类号： A61M31/00 , A61F6/06 , A61F6/08 , A61K9/0036
摘要： A vaginal drug delivery system includes a device formed of porous material that holds a flowable therapeutic formulation. The device, preferably in a soft, prewetted state, is inserted into the vagina to reside typically at or near the cervix where it continuously releases the flowable therapeutic formulation through its outer surface which is in contact with the vaginal surfaces. In operation, the flowable therapeutic formulation migrates via capillary forces from a reservoir that is centrally located in the device and through a covering that envelopes the reservoir.
摘要翻译：阴道药物递送系统包括由多孔材料形成的装置，其保持可流动的治疗剂型。该装置优选地处于柔软的预润湿状态，被插入到阴道中，通常驻留在子宫颈处或附近，其中它连续地通过其与阴道表面接触的外表面释放可流动的治疗剂。在操作中，可流动的治疗制剂通过毛细管力从位于装置中心的储存器并通过包围储存器的覆盖物迁移。

16. 发明申请

WO2007001797A1 INTERACTIVE CABLE TELEVISION SYSTEM WITHOUT A RETURN PATH 审中-公开
标题翻译：没有返回路径的交互式电视电视系统
公开(公告)号：WO2007001797A1
公开(公告)日：2007-01-04
申请号：PCT/US2006/022533
申请日：2006-06-09
申请人： ICTV, INC. , PAVLOVSKAIA, Lena , JOHNSON, Robert , LANDAU, Airan , KOHN, Amos
发明人： PAVLOVSKAIA, Lena , JOHNSON, Robert , LANDAU, Airan , KOHN, Amos
IPC分类号： H04N5/445 , H04N7/16
CPC分类号： H04N21/4782 , H04N7/163 , H04N21/4331 , H04N21/4622 , H04N21/482 , H04N21/6118 , H04N21/6125
摘要： A method for providing interactive information content in an analog cable system having only a one-way communication path from a cable head end to a communication device, such as a set-top box that is associated with a television is disclosed. A set-top box receives a plurality of interactive information content signals on at least one analog channel from the cable head end. In certain embodiments the interactive information content signals are data streams that sent over an analog carrier channel. The set-top box provides a selection screen to the television for display. A user can then use a user-input device, such as, a remote control to make a selection. In general, the user will select a key, such as a directional key and the remote control will provide the selection/directional signal to the set-top box. The set-top box then outputs a new information content signal based the received selection signal without having to transmit to the head end.
摘要翻译：公开了一种在仅具有从电缆头端到通信设备的单向通信路径的模拟电缆系统中提供交互式信息内容的方法，例如与电视机相关联的机顶盒。机顶盒在电缆头端的至少一个模拟通道上接收多个交互式信息内容信号。在某些实施例中，交互式信息内容信号是通过模拟载波信道发送的数据流。机顶盒为电视机提供选择屏幕进行显示。然后，用户可以使用诸如遥控器的用户输入设备进行选择。通常，用户将选择诸如方向键的键，并且遥控器将向机顶盒提供选择/定向信号。然后，机顶盒基于接收到的选择信号输出新的信息内容信号，而不必向头端发送。

17. 发明申请

WO2006118953A3 METHOD OF TREATING MULTIPLE MYELOMA USING 17-AAG OF 17-AG OF A PRODRUG OF EITHER 审中-公开
公开(公告)号：WO2006118953A3
公开(公告)日：2006-11-09
申请号：PCT/US2006/016043
申请日：2006-04-26
申请人： KOSAN BIOSCIENCES INCORPORATED , JOHNSON, Robert , HANNAH, Alison , CROPP, Gillian , ZHOU, Yiqing , SHERRILL, J.
发明人： JOHNSON, Robert , HANNAH, Alison , CROPP, Gillian , ZHOU, Yiqing , SHERRILL, J.
IPC分类号： A61K31/33
摘要： A method for treating multiple myeloma in a subject by administering 17-allylamino- 17-demethoxy-geldanamycin or 17-amino geldanamycin, or a prodrug of either 17-AAG or 17-AG, to the subject.

18. 发明申请

WO2006044395A1 SHAVING RAZORS AND CARTRIDGES 审中-公开
标题翻译：剃须刀和卡盒
公开(公告)号：WO2006044395A1
公开(公告)日：2006-04-27
申请号：PCT/US2005/036543
申请日：2005-10-13
申请人： THE GILLETTE COMPANY , JOHNSON, Robert , TROTTA, Robert, A. , BRIDGES, Kelly
发明人： JOHNSON, Robert , TROTTA, Robert, A. , BRIDGES, Kelly
IPC分类号： B26B21/22
CPC分类号： B26B21/225 , B26B21/222
摘要： Connecting structures are provided, for connecting a cartridge to a handle in a shaving razor, e.g., a razor for wet shaving.
摘要翻译：提供连接结构，用于将药筒连接到剃须刀中的手柄上，例如用于湿剃的剃须刀。

19. 发明申请

WO2006044394A3 SHAVING RAZORS AND CARTRIDGES 审中-公开
公开(公告)号：WO2006044394A3
公开(公告)日：2006-04-27
申请号：PCT/US2005/036542
申请日：2005-10-13
申请人： THE GILLETTE COMPANY , JOHNSON, Robert , TROTTA, Robert, A. , BRIDGES, Kelly , CORBEIL, Corey, E.
发明人： JOHNSON, Robert , TROTTA, Robert, A. , BRIDGES, Kelly , CORBEIL, Corey, E.
IPC分类号： B26B21/44
摘要： Shaving razors (10) and cartridges (12) are featured that include one or more shaving aid portions (31A, 31B) . In some instances, the razors and cartridges include a shaving aid holder (30), configured to allow the shaving aid portion to deflect when pressure is applied to a surface of the shaving aid portion during shaving.

20. 发明申请

WO2003001484A3 MULTI-IMAGE DISPLAY UNIT WITH MEDIUM DISPLACING MECHANISM 审中-公开
公开(公告)号：WO2003001484A3
公开(公告)日：2003-01-03
申请号：PCT/US2002/020277
申请日：2002-06-24
申请人： CAPTIVA HONG KONG LIMITED , KARZMER, David , VITULLO, Jim , STECK, Harry , JOHNSON, Robert
发明人： KARZMER, David , VITULLO, Jim , STECK, Harry , JOHNSON, Robert
IPC分类号： G03B25/02
摘要： A display unit having a frame (110), a wall of lenticular lenses (115) an image-carrying medium (135), an electric motor (230) and a gear assembly (170) for imparting reciprocal vertical motion to the image carrying means.

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