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11. 发明申请

WO2012054296A2 VARIABLE SIZE INTRAGASTRIC IMPLANT DEVICES 审中-公开
标题翻译：可变尺寸INTRAGASTRIC IMPLANT DEVICES
公开(公告)号：WO2012054296A2
公开(公告)日：2012-04-26
申请号：PCT/US2011/056160
申请日：2011-10-13
申请人： ALLERGAN, INC. , BABKES, Mitchell H. , SNOW, Sean
发明人： BABKES, Mitchell H. , SNOW, Sean
IPC分类号： A61F5/00
CPC分类号： A61F5/003 , A61F5/004
摘要： Transoral obesity treatment devices and related methods for operation thereof are described which occupy space within a stomach and/or stimulate the stomach wall. The transoral obesity treatment devices and related methods are intended to assist a patient in maintaining a healthy body weight. Features of the devices include insertion transorally and without invasive surgery, without associated patient risks of invasive surgery, and without substantial patient discomfort. The life span of these devices may be material-dependent upon long-term survivability within an acidic stomach, but is intended to last one year or longer. The devices have the capacity to vary in size and are desirably self-actuating in that they change shape and/or volume using internal motors or actuators. The changing character of the devices helps prevent the person's stomach from compensating for the implant, such as sometimes happens with static intragastric devices.
摘要翻译：描述了跨腹部肥胖症治疗装置及其相关操作方法，其占据胃内的空间和/或刺激胃壁。经腹肥胖治疗装置和相关方法旨在帮助患者保持健康的体重。器件的特征包括经皮插入和无侵入性手术，无相关患者的侵入性手术风险，无明显的患者不适。这些装置的使用寿命可能依赖于酸性胃内的长期生存能力，但意图持续一年或更长时间。这些装置具有在尺寸上变化的能力，并且希望是自动致动，因为它们使用内部电动机或致动器改变形状和/或体积。设备的变化特征有助于防止人的胃部补偿植入物，例如有时会发生静态胃内装置。

12. 发明申请

WO2012054300A2 ELEVATING STOMACH STIMULATION DEVICE 审中-公开
标题翻译：提醒胃刺激设备
公开(公告)号：WO2012054300A2
公开(公告)日：2012-04-26
申请号：PCT/US2011/056175
申请日：2011-10-13
申请人： ALLERGAN, INC. , BABKES, Mitchell H.
发明人： BABKES, Mitchell H.
IPC分类号： A61F5/00
CPC分类号： A61F5/0043 , A61F5/003 , A61F5/0036
摘要： The medical systems, apparatuses and uses thereof for treating obesity and/or obesity-related diseases are provided which relate to devices designed to stimulate an internal surface of the stomach such as the cardia. Features of the obesity treatment devices include insertion of said devices transorally and without invasive surgery, without associated patient risks of invasive surgery, and without substantial patient discomfort. The devices include flotation portions and cardia-stimulating portions, so that as the level of stomach contents rise, the devices will contact and stimulate the nerves in the cardia region of the stomach to induce satiety. The devices may have non-inflatable balls, be made of skinned foam, have ballast members such as a weighted ball or quantity of saline for orientation, and various combinations thereof.
摘要翻译：提供了用于治疗肥胖症和/或肥胖症相关疾病的医疗系统，设备和用途，其涉及设计用于刺激胃内部表面如贲门的装置。肥胖治疗装置的特征包括经口插入所述装置并且没有侵入性手术，没有相关的患者侵入性手术风险，并且没有实质性的患者不适。这些装置包括浮动部分和贲门刺激部分，从而随着胃内容物水平上升，装置将接触并刺激胃的贲门区域中的神经以引起饱腹感。这些装置可以具有不可充气的球体，由表皮泡沫制成，具有诸如加重球的压载构件或用于取向的量的盐水，以及它们的各种组合。

13. 发明申请

WO2013074364A1 MODULAR INJECTION SYSTEM AND METHOD FOR DILUTING AN INJECTABLE FLUID 审中-公开
标题翻译：模块化注射系统和用于稀释注射液的方法
公开(公告)号：WO2013074364A1
公开(公告)日：2013-05-23
申请号：PCT/US2012/064106
申请日：2012-11-08
申请人： ALLERGAN, INC.
发明人： MUDD, Christopher S. , DOMINGUEZ, Zachary P. , JOSENHANS, Corey L. , TEZEL, Ahmet , BABKES, Mitchell H. , PRICHARD, Michael J. , LLEWELLYN, Martha E. , QIU, Shaohui , POWERS, Lee F. , JOHNSON, Brett R.
IPC分类号： A61M5/14 , A61M5/142 , A61M5/145 , A61M5/19 , A61C5/06 , A61M5/24
CPC分类号： A61M5/1408 , A61M5/14244 , A61M5/1452 , A61M5/14526 , A61M5/16827 , A61M5/172 , A61M5/19 , A61M2209/088
摘要： A modular injection system enables a user to control the dilution ratio of mixed injectable fluid. In one embodiment, modular injection system includes a handheld injection device operatively connected to a separate control device. In one embodiment, the control device includes a drive unit configured to apply extrusion forces to fluids. In another embodiment, the handheld injection device includes the drive unit. In one embodiment, the modular injection system produces the mixed injectable fluid based on a selected dilution ratio. In one embodiment, the modular injection system produces the mixed injectable fluid based on selected injection rates.
摘要翻译：模块化注射系统使得用户能够控制混合可注射流体的稀释比。在一个实施例中，模块化注射系统包括可操作地连接到单独的控制装置的手持式注射装置。在一个实施例中，控制装置包括构造成将挤压力施加到流体的驱动单元。在另一个实施例中，手持式注射装置包括驱动单元。在一个实施例中，模块化注射系统基于所选择的稀释比产生混合的可注射流体。在一个实施例中，模块化注射系统基于所选择的注射速率产生混合的可注射流体。

14. 发明申请

WO2013074344A1 INJECTION DEVICE AND METHOD FOR DILUTING AN INJECTABLE FLUID 审中-公开
标题翻译：注射装置和喷射注射液的方法
公开(公告)号：WO2013074344A1
公开(公告)日：2013-05-23
申请号：PCT/US2012/063847
申请日：2012-11-07
申请人： ALLERGAN, INC.
发明人： MUDD, Christopher S. , BABKES, Mitchell H. , DOMINGUEZ, Zachary P. , PRICHARD, Michael J. , LLEWELLYN, Martha E. , QIU, Shaohui , POWERS, Lee F. , JOHNSON, Brett R.
IPC分类号： A61M5/20 , A61M5/19
CPC分类号： A61M5/1407 , A61M5/172 , A61M5/19 , A61M5/2448 , A61M5/284 , A61M2205/33 , A61M2205/50
摘要： An injection device enables a user to control the dilution ratio of mixed injectable fluid. In one embodiment, the injection device includes a drive unit configured to apply extrusion forces to fluids. In one embodiment, the injection device produces the mixed injectable fluid based on a selected dilution ratio. In one embodiment, the injection device produces the mixed injectable fluid based on selected injection rates.
摘要翻译：注射装置使得使用者能够控制混合注射液的稀释比。在一个实施例中，注射装置包括构造成将挤压力施加到流体的驱动单元。在一个实施例中，注射装置基于选定的稀释比产生混合的可注射流体。在一个实施例中，注射装置基于所选择的注射速率产生混合的可注射流体。

15. 发明公开

EP2780060A1 INJECTION DEVICE AND METHOD FOR DILUTING AN INJECTABLE FLUID 审中-公开
标题翻译： VERFAHREN ZUMVERDÜNNENEINER INJIZIERBARENFLÜSSIGKEIT
公开(公告)号：EP2780060A1
公开(公告)日：2014-09-24
申请号：EP12788048.2
申请日：2012-11-07
申请人： ALLERGAN, INC.
发明人： MUDD, Christopher S. , BABKES, Mitchell H. , DOMINGUEZ, Zachary P. , PRICHARD, Michael J. , LLEWELLYN, Martha E. , QIU, Shaohui , POWERS, Lee F. , JOHNSON, Brett R.
IPC分类号： A61M5/20 , A61M5/19
CPC分类号： A61M5/1407 , A61M5/172 , A61M5/19 , A61M5/2448 , A61M5/284 , A61M2205/33 , A61M2205/50
摘要： An injection device enables a user to control the dilution ratio of mixed injectable fluid. In one embodiment, the injection device includes a drive unit configured to apply extrusion forces to fluids. In one embodiment, the injection device produces the mixed injectable fluid based on a selected dilution ratio. In one embodiment, the injection device produces the mixed injectable fluid based on selected injection rates.
摘要翻译：注射装置使得用户能够控制混合注射液的稀释比。在一个实施例中，注射装置包括构造成将挤压力施加到流体的驱动单元。在一个实施方案中，注射装置基于选定的稀释比产生混合的可注射流体。在一个实施例中，注射装置基于所选择的注射速率产生混合的可注射流体。

16. 发明公开

EP2685945A2 SELF-ADJUSTING GASTRIC BAND 审中-公开
标题翻译：自我调节胃带
公开(公告)号：EP2685945A2
公开(公告)日：2014-01-22
申请号：EP12713446.8
申请日：2012-03-14
申请人： Allergan, Inc.
发明人： SNOW, Sean , BABKES, Mitchell H. , BORRELL, Marcos , DEUEL, Christopher R. , DOMINGUEZ, Zachary P. , FRANKLIN, Ethan , HONARYAR, Babak , TORJESEN, Erik
IPC分类号： A61F5/00 , A61B5/00
CPC分类号： A61F5/0056
摘要： Generally described herein are automatic, self-adjusting, gastric banding systems and improvements thereof, that are capable of automatically relaxing and contracting in response to a large bolus passing through the area of a patient's stomach constricted by a gastric band. Alternatively, and/or in addition in one or more embodiments, the gastric banding systems described herein may also help prevent pouch dilatation and/or erosion. The apparatus and systems described herein aid in facilitating obesity control and/or treating obesity-related diseases while generally being non-invasive once implanted. Furthermore, certain embodiments of the self-adjusting gastric banding systems disclosed herein are automatically adjustable without complicated fluid control mechanisms, flow rate limiting devices, and/or valves. The automatic adjustments may also be made in response to other changes in the patient's esophageal-gastric junction, for example, in response to size, shape, and or location changes.
摘要翻译：一般在此描述的是自动的，自我调节的胃束带系统及其改进，其能够响应于大丸通过胃带收缩的患者胃部区域而自动放松和收缩。可替代地和/或另外在一个或多个实施例中，本文所述的胃束带系统还可以帮助防止囊扩张和/或侵蚀。本文所述的装置和系统有助于促进肥胖控制和/或治疗肥胖相关疾病，而一旦植入则通常是非侵入性的。此外，本文公开的自调节胃束带系统的某些实施例可自动调节而无需复杂的流体控制机构，流量限制装置和/或阀。例如，响应于患者的食管 - 胃连接处的其他变化，响应于尺寸，形状和/或位置变化，也可以进行自动调整。

17. 发明公开

EP2629714A2 INTRAGASTRIC IMPLANTS WITH DUODENAL ANCHORS 有权
标题翻译：麦当劳麻醉剂DUODENALEN VERANKERUNGEN
公开(公告)号：EP2629714A2
公开(公告)日：2013-08-28
申请号：EP11773976.3
申请日：2011-10-18
申请人： Allergan, Inc.
发明人： DOMINGUEZ, Zachary P. , RAVEN, Joseph S. , BABKES, Mitchell H.
IPC分类号： A61F5/00
CPC分类号： A61F5/0033 , A61F5/0036 , A61F5/0079
摘要： Intragastric fluid transfer devices and related methods for operation thereof are disclosed. The intragastric fluid transfer devices and related methods are intended to assist a patient in maintaining a healthy body weight by stimulating the inner stomach walls and/or the inner duodenum walls. Features of the intragastric fluid transfer device include insertion of the devices transorally and without invasive surgery, without associated patient risks of invasive surgery, and without substantial patient discomfort. The life span of these intragastric fluid transfer devices may be material-dependent upon long-term survivability within an acidic stomach, but is intended to last one year or longer.
摘要翻译：公开了胃内液体输送装置及其操作方法。胃内液体输送装置和相关方法旨在通过刺激内壁和/或十二指肠内壁来帮助患者维持健康的体重。胃内液体输送装置的特征包括经皮和无侵入性手术的装置插入，没有相关患者的侵入性手术风险，并且没有大量的患者不适。这些胃内液体输送装置的使用寿命可以依赖于在酸性胃内的长期存活性，但是其持续一年或更长时间。

18. 发明公开

EP2629709A2 INTRAGASTRIC IMPLANTS WITH COLLAPSIBLE FRAMES 有权转让
标题翻译：胃植入物可折叠的框架
公开(公告)号：EP2629709A2
公开(公告)日：2013-08-28
申请号：EP11770988.1
申请日：2011-10-13
申请人： Allergan, Inc.
发明人： DOMINGUEZ, Zachary P. , BABKES, Mitchell H. , SCHWAB, Justin J. , MUDD, Christopher S. , HOOVER, Jason
IPC分类号： A61F5/00
CPC分类号： A61F5/0036 , A61F5/0033 , A61F5/0079 , A61F5/0086 , A61F5/0089
摘要： Transoral obesity treatment devices and related methods for operation thereof are described which occupy space within a stomach and/or stimulate the stomach wall. The transoral obesity treatment devices and related methods are intended to assist a patient in maintaining a healthy body weight. Features of the devices include insertion transorally and without invasive surgery, without associated patient risks of invasive surgery, and without substantial patient discomfort. The life span of these devices may be material-dependent upon long-term survivability within an acidic stomach, but is intended to last one year or longer. The devices have the capacity to vary in size and are desirably self-actuating in that they change shape and/or volume using internal motors or actuators. The changing character of the devices helps prevent the person's stomach from compensating for the implant, such as sometimes happens with static intragastric devices.

19. 发明公开

EP2780053A1 MODULAR INJECTION SYSTEM AND METHOD FOR DILUTING AN INJECTABLE FLUID 审中-公开
标题翻译：模块化喷射系统的方法对薄可注射的液体
公开(公告)号：EP2780053A1
公开(公告)日：2014-09-24
申请号：EP12794590.5
申请日：2012-11-08
申请人： ALLERGAN, INC.
发明人： MUDD, Christopher S. , DOMINGUEZ, Zachary P. , JOSENHANS, Corey L. , TEZEL, Ahmet , BABKES, Mitchell H. , PRICHARD, Michael J. , LLEWELLYN, Martha E. , QIU, Shaohui , POWERS, Lee F. , JOHNSON, Brett R.
IPC分类号： A61M5/14 , A61M5/142 , A61M5/145 , A61M5/19 , A61C5/06 , A61M5/24
CPC分类号： A61M5/1408 , A61M5/14244 , A61M5/1452 , A61M5/14526 , A61M5/16827 , A61M5/172 , A61M5/19 , A61M2209/088
摘要： A modular injection system enables a user to control the dilution ratio of mixed injectable fluid. In one embodiment, modular injection system includes a handheld injection device operatively connected to a separate control device. In one embodiment, the control device includes a drive unit configured to apply extrusion forces to fluids. In another embodiment, the handheld injection device includes the drive unit. In one embodiment, the modular injection system produces the mixed injectable fluid based on a selected dilution ratio. In one embodiment, the modular injection system produces the mixed injectable fluid based on selected injection rates.

20. 发明公开

EP2629718A2 ELEVATING STOMACH STIMULATION DEVICE 有权转让
标题翻译：与ERHÖHUNGSMECHANIMUS胃刺激装置，
公开(公告)号：EP2629718A2
公开(公告)日：2013-08-28
申请号：EP11790812.9
申请日：2011-10-13
申请人： Allergan, Inc.
发明人： BABKES, Mitchell H.
IPC分类号： A61F5/00
CPC分类号： A61F5/0043 , A61F5/003 , A61F5/0036
摘要： The medical systems, apparatuses and uses thereof for treating obesity and/or obesity-related diseases are provided which relate to devices designed to stimulate an internal surface of the stomach such as the cardia. Features of the obesity treatment devices include insertion of said devices transorally and without invasive surgery, without associated patient risks of invasive surgery, and without substantial patient discomfort. The devices include flotation portions and cardia-stimulating portions, so that as the level of stomach contents rise, the devices will contact and stimulate the nerves in the cardia region of the stomach to induce satiety. The devices may have non-inflatable balls, be made of skinned foam, have ballast members such as a weighted ball or quantity of saline for orientation, and various combinations thereof.

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