专利快速检索-快速检索全球专利，免费商用专利数据库-IPRDB

11. 发明申请

WO2007146119A2 BIODEGRADABLE POLYMER ADHESION BARRIERS 审中-公开
标题翻译：生物可降解聚合物粘合障碍物
公开(公告)号：WO2007146119A2
公开(公告)日：2007-12-21
申请号：PCT/US2007013501
申请日：2007-06-08
申请人： MEDIVAS LLC , CARPENTER KENNETH W , ZHANG HUASHI
发明人： CARPENTER KENNETH W , ZHANG HUASHI
IPC分类号： A61M35/00 , C08G63/685
CPC分类号： C08L77/12 , C09J177/12
摘要： The present invention provides adhesion barrier compositions based on a solution of at least one of a biodegradable polyester amide (PEA), polyester urethane (PEUR), or polyester urea (PEU) polymers, dissolved in a biocompatible solvent. The compositions can be applied to a tissue surface, such as in open surgery, as a viscous liquid which forms an adhesive film upon being sprayed or painted onto the tissue surface. Alternatively, the composition can be applied to the tissue surface as a preformed solid layer or double layer (either porous or non-porous) that adheres to the tissue surface. In open surgery, the invention adhesion barrier compositions are used to separate opposing tissue surfaces or tissue-organ surfaces while injured tissues heal, for example in the abdomen or pelvis.
摘要翻译：本发明提供了基于溶解在生物相容性溶剂中的可生物降解的聚酯酰胺（PEA），聚酯聚氨酯（PEUR）或聚酯尿素（PEU）聚合物中的至少一种的溶液的粘合屏障组合物。组合物可以施用于组织表面，例如在开放手术中，作为在被喷涂或涂在组织表面上时形成粘合剂膜的粘性液体。或者，组合物可以作为预先形成的固体层或粘附于组织表面的双层（多孔或无孔）施用于组织表面。在开放手术中，本发明的粘合屏障组合物用于在损伤的组织愈合时，例如在腹部或骨盆中分离相对的组织表面或组织器官表面。

12. 发明申请

WO2007035938A3 BIS-(a-AMINO)-DIOL-DIESTER-CONTAINING POLY(ESTER AMIDE) AND POLY(ESTER URETHANE) COMPOSITIONS AND METHODS OF USE 审中-公开
标题翻译： BIS-（a-AMINO） - 含外消旋聚合物（酯化酰胺）和聚（酯）尿酸酯组合物和使用方法
公开(公告)号：WO2007035938A3
公开(公告)日：2007-05-31
申请号：PCT/US2006037331
申请日：2006-09-22
申请人： MEDIVAS LLC , GOMURASHVILI ZAZA D , HUGHES JONATHAN MACFERRAN , DA JIE NMN , ZHANG HUASHI
发明人： GOMURASHVILI ZAZA D , HUGHES JONATHAN MACFERRAN , DA JIE NMN , ZHANG HUASHI
IPC分类号： C08L77/00 , A61F2/00 , A61L31/00 , C08G18/10 , C08G69/44 , C08L75/04 , C08L77/12
CPC分类号： C08L77/12 , A61L31/041 , A61L31/06 , A61L31/148 , C08G69/44
摘要： The present invention provides biodegradable, biocompatible bis -(a-amino acyl)-diol-diester-containing poly(ester amide) (PEA) and poly(ester urethane) (PEUR) co-polymer compositions with mechanical properties that can be readily tailored by selection of various combinations and proportions of the building blocks of the co-polymers. The compositions are suitable for use in production of drug-releasing biodegradable particles and implantable surgical devices, such as stents and internal fixation devices. The co-polymer compositions, particles and surgical devices biodegrade in vivo by enzymatic action to release bioactive agents in a controlled manner over time as well as biocompatible breakdown products, including one to multiple different amino acids.
摘要翻译：本发明提供具有机械特性的可生物降解的生物相容性的双（α-氨基酰基） - 二醇 - 二酯的聚（酯酰胺）（PEA）和聚（酯聚氨酯）（PEUR）共聚物组合物，其可以容易地定制通过选择共聚物的结构单元的各种组合和比例。该组合物适合用于生产释放药物的可生物降解颗粒和可植入手术装置，如支架和内固定装置。共聚合物组合物，颗粒和手术装置通过酶作用在体内生物降解，以随时间的控制方式释放生物活性剂以及生物相容的分解产物，包括一至多个不同的氨基酸。

13. 发明申请

WO2007035938A2 BIS-(α-AMINO)-DIOL-DIESTER-CONTAINING POLY(ESTER AMIDE) AND POLY(ESTER URETHANE) COMPOSITIONS AND METHODS OF USE 审中-公开
标题翻译：含BIS-（α-氨基） - 二醇 - 二酯的聚（酯酰胺）和聚（酯氨基甲酸酯）组合物及使用方法
公开(公告)号：WO2007035938A2
公开(公告)日：2007-03-29
申请号：PCT/US2006/037331
申请日：2006-09-22
申请人： MEDIVAS, LLC , GOMURASHVILI, Zaza, D. , HUGHES, Jonathan, Macferran , DA, Jie, Nmn , ZHANG, Huashi
发明人： GOMURASHVILI, Zaza, D. , HUGHES, Jonathan, Macferran , DA, Jie, Nmn , ZHANG, Huashi
CPC分类号： C08L77/12 , A61L31/041 , A61L31/06 , A61L31/148 , C08G69/44
摘要： The present invention provides biodegradable, biocompatible bis -(α-amino acyl)-diol-diester-containing poly(ester amide) (PEA) and poly(ester urethane) (PEUR) co-polymer compositions with mechanical properties that can be readily tailored by selection of various combinations and proportions of the building blocks of the co-polymers. The compositions are suitable for use in production of drug-releasing biodegradable particles and implantable surgical devices, such as stents and internal fixation devices. The co-polymer compositions, particles and surgical devices biodegrade in vivo by enzymatic action to release bioactive agents in a controlled manner over time as well as biocompatible breakdown products, including one to multiple different amino acids.
摘要翻译：本发明提供了可生物降解的，生物相容的含双 - （α-氨基酰基） - 二醇 - 二酯的聚（酯酰胺）（PEA）和聚（酯氨基甲酸乙酯）（PEUR）共聚物组合物其机械性能可通过选择共聚物结构单元的各种组合和比例而容易地定制。该组合物适用于生产释放药物的生物可降解颗粒和可植入手术装置，例如支架和内固定装置。共聚物组合物，颗粒和手术装置通过酶促作用在体内生物降解以随时间以受控方式释放生物活性剂以及生物相容性分解产物，包括一种到多种不同的氨基酸。

你已经成功收藏专利！

检索式保存成功!

IPRDB

热门服务

关于我们

友情链接

联系方式