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11. 发明申请

WO0111247A3 METHOD OF IMPROVING SHEAR STRENGTH OF BOLTED JOINT 审中-公开
标题翻译：提高螺栓接头剪切强度的方法
公开(公告)号：WO0111247A3
公开(公告)日：2007-11-29
申请号：PCT/AU0000944
申请日：2000-08-04
申请人： WEEKS PEACOCK QUALITY HOMES , WEEKS KEVIN WILLIAM
发明人： WEEKS KEVIN WILLIAM
IPC分类号： F16B5/00 , B21D39/03 , B23P11/00 , E04B1/24 , E04B1/58 , E04B2/58 , E04B2/60 , E04C3/04 , E04C3/40
CPC分类号： E04B1/2403 , E04B2001/2415
摘要： A method of improving the shear strength of a bolted joint involves pressing bosses (14) in planar members (10, 18) and abutting the planar members front to rear (figure 3) such that the bosses closely nest one within the other to thereby restrain the members against relative planar movement.
摘要翻译：提高螺栓接头的剪切强度的方法包括将平面构件（10,18）中的凸台（14）压紧并抵靠平面构件的前后（图3），使得凸台将一个嵌套在另一个内部，从而约束成员抵抗相对平面运动。

12. 发明申请

WO2003008722A1 TRUSS 审中-公开
标题翻译：桁架
公开(公告)号：WO2003008722A1
公开(公告)日：2003-01-30
申请号：PCT/AU2002/000788
申请日：2002-06-14
申请人： WEEKS PEACOCK QUALITY HOMES PTY. LTD. , WEEKS, Kevin, William
发明人： WEEKS, Kevin, William
IPC分类号： E04B1/32
CPC分类号： E04C3/40 , E04C3/07 , E04C3/11
摘要： A truss (10) for a roof having an attic space or the like, the truss including: a substantially vertical web (15, 16) adapted to constitute a stud for supporting the attic wall; a substantially horizontal web (14) adapted to constitute a support for the attic ceiling or ceiling battens, and a bottom chord (11) adapted to constitute a bearer or joist for the attic floor.
摘要翻译：一种用于具有阁楼空间等的屋顶的桁架（10），所述桁架包括：适于构成用于支撑阁楼壁的螺柱的基本垂直的腹板（15,16）; 适于构成用于阁楼天花板或天花板条板的支撑件的基本上水平的卷筒纸（14），以及适于构成阁楼底板的托架或托梁的底部弦杆（11）。

13. 发明申请

WO0123612A2 METHODS AND KITS FOR DETERMINING MUTATIONS, LOCAL CONFORMATIONAL CHANGES, AND AMOUNTS OF NUCLEIC ACIDS BY SELECTIVE REACTION OF THE 2'-RIBOSE POSITION IN HYBRIDIZED OLIGONUCLEOTIDES 审中-公开
标题翻译：用于通过选择性反应混合寡核苷酸中2'-位置位置来确定突变，局部一致性变化和核酸含量的方法和试剂盒
公开(公告)号：WO0123612A2
公开(公告)日：2001-04-05
申请号：PCT/US0026320
申请日：2000-09-25
申请人： UNIV NORTH CAROLINA , WEEKS KEVIN , CHAMBERLIN STACY I , JOHN DEBORAH M
发明人： WEEKS KEVIN , CHAMBERLIN STACY I , JOHN DEBORAH M
IPC分类号： C12Q1/68
CPC分类号： C12Q1/6827
摘要： New chemical tagging methods and kits of the present invention utilize the discovery that chemical modification ( e.g. , acylation) of 2'-substituted ribonucleotides or deoxyribonucleotides by reactive compounds ( e.g. , activated esters) is sensitive to the base-paired state of the nucleotide. Perfectly base-paired positions are generally unreactive, while mismatched or unmatched bases are reactive under a wide variety of reaction conditions. The methods of the invention include a method of detecting a mutation in a nucleic acid molecule suspected of containing a mutation. The nucleic acid is hybridized to an oligonucleotide having a sequence complementary to the sequence the nucleic acid would have if a mutation were not present. The oligonucleotide comprises at least one nucleotide with a substitution at the 2'-ribose position. After the oligonucleotide is hybridized to the nucleic acid molecule, the hybridized oligonucleotide is then contacted with a reactive compound comprising a reporter moiety. Detection of the binding of the reporter moiety to the hybridized oligonucleotide indicates a mismatch i.e. , a mutation) in the nucleic acid molecule. The methods and kits of the present invention are useful in detecting point mutations and other defects in nucleic acid sequences. These methods and kits are also useful for detecting single nucleotide polymorphisms (SNPs) and mutations responsible for cancer and other genetic diseases in humans; for quantifying amounts of nucleic acids; and for detecting conformational changes in nucleic acid structures, including those found in the products of in vitro selection experiments i.e. , aptamers).
摘要翻译：本发明的新的化学标记方法和试剂盒利用这样的发现，即通过反应性化合物（例如，活化的）化学修饰（例如，酰化）2'-取代的核糖核苷酸或脱氧核糖核苷酸酯）对核苷酸的碱基配对状态敏感。完全碱基配对的位置通常是不反应的，而不匹配或不匹配的碱基在多种反应条件下是反应性的。本发明的方法包括检测疑似含有突变的核酸分子中的突变的方法。如果不存在突变，则核酸与具有与核酸将具有的序列互补的序列的寡核苷酸杂交。寡核苷酸包含至少一个在2'-核糖位置具有取代的核苷酸。寡核苷酸与核酸分子杂交后，然后将杂交的寡核苷酸与包含报道部分的反应性化合物接触。报道部分与杂交寡核苷酸结合的检测表明核酸分子中的错配（即突变）。本发明的方法和试剂盒可用于检测核酸序列中的点突变和其他缺陷。这些方法和试剂盒也可用于检测负责人类癌症和其他遗传疾病的单核苷酸多态性（SNPs）和突变; 用于量化核酸量; 并且用于检测核酸结构中的构象变化，包括在体外选择实验，适配子的产物中发现的构象变化。

14. 发明申请

WO2007145940A3 HIGH-THROUGHPUT RNA STRUCTURE ANALYSIS 审中-公开
标题翻译：高通量RNA结构分析
公开(公告)号：WO2007145940A3
公开(公告)日：2008-04-10
申请号：PCT/US2007013226
申请日：2007-06-05
申请人： UNIV NORTH CAROLINA , WEEKS KEVIN M , WILKINSON KEVIN , VASA SUZY A , GIDDINGS MORGAN C , GUEX NICOLAS , MORTIMER STEFANIE A
发明人： WEEKS KEVIN M , WILKINSON KEVIN , VASA SUZY A , GIDDINGS MORGAN C , GUEX NICOLAS , MORTIMER STEFANIE A
IPC分类号： C12P19/34 , C07F9/02 , C07H21/00 , C07H21/02 , G01N33/48
CPC分类号： G06F19/16 , C12Q1/6811 , C12Q2565/133
摘要： Te presently disclosed subject matter relates to technology and methods for analyzing the structure of RNA molecules. More particularly, the presently disclosed subject matter is directed to methods of, compositions for, and computer program products for RNA structure analysis through alkoxide- selective 2'-hydroxyl acylation analyzed by primer extension.
摘要翻译：目前公开的主题涉及用于分析RNA分子结构的技术和方法。更具体地，目前公开的主题涉及通过引物延伸分析的通过醇盐选择性2'-羟基酰化进行RNA结构分析的方法，组合物和计算机程序产品。

15. 发明申请

WO2004088058A1 TRUSS-PURLIN CONNECTION & TRUSS-BATTEN CONNECTION 审中-公开
标题翻译： TRUSS-PURLIN连接和TRUSS-BATTEN连接
公开(公告)号：WO2004088058A1
公开(公告)日：2004-10-14
申请号：PCT/AU2004/000420
申请日：2004-03-29
申请人： WEEKS PEACOCK QUALITY HOMES PTY. LTD. , WEEKS, Kevin, William
发明人： WEEKS, Kevin, William
IPC分类号： E04C3/11
CPC分类号： E04C3/11 , E04B7/024 , E04C3/07
摘要： A truss-purlin assembly includes opposed tabs (22) punched out of the upper chord (12) of a roof truss (10) which receive flanges (24) of a roof purlin (18). The flanges (24) can be resiliently deflected in the direction of arrows (28) during assembly of the roof purlin (18) with upper chord (12). The flanges (24) include corrugations (26) which prevent longitudinal movement of the roof purlin (18) relative to the upper chord (12). The invention is also equally applicable to a truss-batten assembly.
摘要翻译：桁架桁架组件包括冲压出顶板桁架（10）的上弦（12）的相对的翼片（22），其接收屋顶pur条（18）的凸缘（24）。在顶部pur条（18）与上弦（12）组装期间，凸缘（24）可以在箭头（28）的方向上弹性偏转。凸缘（24）包括波纹（26），其防止屋顶pur条（18）相对于上弦杆（12）的纵向移动。本发明也同样适用于桁架板组件。

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