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11. 发明申请

US20070217949A1 Quality control system 有权
标题翻译：质量控制体系
公开(公告)号：US20070217949A1
公开(公告)日：2007-09-20
申请号：US11710424
申请日：2007-02-26
申请人： Tomonori Mimura , Kazumitsu Kawase
发明人： Tomonori Mimura , Kazumitsu Kawase
IPC分类号： G01N33/00
CPC分类号： G01N35/00603 , G01N35/00613 , G01N35/00712 , Y10T436/11 , Y10T436/113332 , Y10T436/115831 , Y10T436/2575
摘要： In a clinical laboratory of a hospital, an enormous amount of effort has been required to maintain the quality of an analyzer, standard solution and control samples. An object of the present invention is to provide a control method for controlling a clinical laboratory with reduced cost, and a control apparatus using the same.In order to control data of an analyzer, standard solution, and a control sample, a support center is connected to each analyzer located in each hospital through a network line. Various kinds of analysis parameters and the result of measurements are exchanged so as to provide each clinical laboratory with a control situation in real time.
摘要翻译：在医院的临床实验室，需要大量的努力来保持分析仪，标准溶液和对照样品的质量。本发明的目的是提供一种用于以降低的成本控制临床实验室的控制方法和使用该控制方法的控制装置。为了控制分析仪，标准解决方案和控制样本的数据，支持中心通过网络线连接到位于每个医院的每个分析仪。交换各种分析参数和测量结果，以便为每个临床实验室提供实时的控制情况。

12. 发明申请

US20070009387A1 Chemical analysis apparatus and chemical analysis method 有权
标题翻译：化学分析仪器和化学分析方法
公开(公告)号：US20070009387A1
公开(公告)日：2007-01-11
申请号：US11522379
申请日：2006-09-18
申请人： Hajime Katou , Ryo Miyake , Hiroyasu Uchida , Katsuhiro Kambara , Takenori Okusa , Shigenori Watari , Yoichiro Suzuki , Tomonori Mimura , Miki Taki , Akira Inagaki
发明人： Hajime Katou , Ryo Miyake , Hiroyasu Uchida , Katsuhiro Kambara , Takenori Okusa , Shigenori Watari , Yoichiro Suzuki , Tomonori Mimura , Miki Taki , Akira Inagaki
IPC分类号： G01N33/00
CPC分类号： G01N35/1002 , B01F11/0283 , B01F2215/0037 , G01N35/025 , G01N2035/00554 , Y10S707/962 , Y10S707/99933 , Y10S707/99942 , Y10S707/99943 , Y10S707/99956
摘要： A chemical analysis apparatus in which a sample to be analyzed and a reagent are placed into a reaction container, and sound waves are irradiated to said reaction container so as to agitate them, wherein said chemical analysis apparatus comprises a piezoelectric element producing said sound waves, and drivers for driving said piezoelectric element, said sound waves being intermittently irradiated into said reaction container.
摘要翻译：一种化学分析装置，其中将待分析样品和试剂置于反应容器中，并且将声波照射到所述反应容器以搅拌它们，其中所述化学分析装置包括产生所述声波的压电元件，以及用于驱动所述压电元件的驱动器，所述声波被间歇地照射到所述反应容器中。

13. 发明申请

US20060110288A1 Analyzer system having sample rack transfer line 有权
公开(公告)号：US20060110288A1
公开(公告)日：2006-05-25
申请号：US11324299
申请日：2006-01-04
申请人： Tomonori Mimura , Hiroshi Mitsumaki , Tadashi Ohishi , Taku Sakazume
发明人： Tomonori Mimura , Hiroshi Mitsumaki , Tadashi Ohishi , Taku Sakazume
IPC分类号： G01N35/00
CPC分类号： G01N35/00663 , G01N35/0092 , G01N35/02 , G01N35/026 , G01N2035/00326 , G01N2035/00673 , G01N2035/0453 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/114998 , Y10T436/115831
摘要： A plurality of analyzer units for serum, a plurality of analyzer units for blood plasma and a plurality of analyzer units for urine are arranged along a main transfer line for transferring a sample rack from a rack providing portion to a rack storage portion. A reagent bottle for inspecting liver function is contained in each reagent delivery mechanism of two analyzer units among the plurality of analyzer units for serum. When the reagent for inspecting liver function in one of the two analyzer units is to be short, analysis for the liver function analysis item to samples can be continued by transferring a sample rack from the rack providing portion to the other analyzer unit.

14. 发明申请

US20060039823A1 Chemical analysis apparatus 审中-公开
标题翻译：化学分析仪
公开(公告)号：US20060039823A1
公开(公告)日：2006-02-23
申请号：US11204344
申请日：2005-08-16
申请人： Hironobu Yamakawa , Hideo Enoki , Kunio Harada , Sakuichiro Adachi , Tomonori Mimura
发明人： Hironobu Yamakawa , Hideo Enoki , Kunio Harada , Sakuichiro Adachi , Tomonori Mimura
IPC分类号： G01N35/00
CPC分类号： G01N35/1016 , B01F11/0071 , B01F13/0071 , B01F13/0076 , B01L3/502746 , B01L3/502784 , B01L2200/0605 , B01L2300/0654 , B01L2300/0867 , B01L2300/089 , B01L2400/0427 , F04B19/006 , G01N2035/00158 , G01N2035/00237 , G01N2035/102
摘要： A chemical analysis apparatus is equipped with analysis sections having openings, means for supplying samples or reagents from the openings, means for combining and mixing samples with reagents to obtain droplets as liquids to be measured, and means for measuring the physical properties of the liquids to be measured during reaction or after completion of reaction. Furthermore, plate members are provided facing each other in analysis sections and a plurality of electrodes are provided on the plate member faces that face each other. Voltage is applied from the plurality of electrodes to the droplets of the samples and the reagents.
摘要翻译：化学分析装置配备有具有开口的分析部分，用于从开口供应样品或试剂的装置，用于将样品与试剂混合并混合以获得待测量液体的液滴的装置，以及用于测量液体的物理性质的装置在反应期间或反应完成后测量。此外，在分析部分中彼此面对地设置板构件，并且在彼此相对的板构件面上设置多个电极。电压从多个电极施加到样品和试剂的液滴。

15. 发明授权

US5985215A Analyzing apparatus having a function pipette samples 失效
标题翻译：分析具有功能移液器样品的设备
公开(公告)号：US5985215A
公开(公告)日：1999-11-16
申请号：US934664
申请日：1997-09-22
申请人： Taku Sakazume , Hiroshi Mitsumaki , Tomonori Mimura , Kazumitsu Kawase
发明人： Taku Sakazume , Hiroshi Mitsumaki , Tomonori Mimura , Kazumitsu Kawase
IPC分类号： G01N35/00 , G01N35/02 , G01N35/04 , G01N35/10
CPC分类号： G01N35/10 , G01N35/026 , G01N2035/00326 , G01N2035/0465 , G01N2035/0493 , Y10T436/11 , Y10T436/113332 , Y10T436/114165 , Y10T436/114998 , Y10T436/115831 , Y10T436/119163
摘要： In an analyzing apparatus of the present invention, sample racks, in each of which a plurality of sample containers are held, are transferred from a rack feeding unit to a discrimination unit for discriminating a type of each sample container. After the discrimination unit, a plurality of analyzing units are installed along a transfer line, and pipetters of different types are provided in the respective analyzing units. The discrimination unit detects information on the length and the width of each sample container held in each sample rack by using an optical detector. A control part selects one of the analyzing units, suitable for analyzing the sample container of which type was discriminated, based on the information detected by the discrimination unit, and transfers the sample container of which type was discriminated, to a sample pipetting position in the selected analyzing unit.
摘要翻译：在本发明的分析装置中，将保持多个样本容器的样品架从架子供给单元传送到识别单元，以区分每个样品容器的类型。在识别单元之后，沿着传送线安装多个分析单元，并且在各个分析单元中设置不同类型的移液器。鉴别单元通过使用光学检测器来检测保持在每个样品架中的每个样品容器的长度和宽度的信息。控制部件基于由识别单元检测到的信息来选择适合于分析被识别类型的样本容器的分析单元之一，并将所识别的类型的样品容器转移到样品移液位置选择分析单位。

16. 发明授权

US09562917B2 Automatic analysis device and automatic analysis program 有权
标题翻译：自动分析装置和自动分析程序
公开(公告)号：US09562917B2
公开(公告)日：2017-02-07
申请号：US14117717
申请日：2012-04-17
申请人： Chihiro Manri , Satoshi Mitsuyama , Tomonori Mimura , Kumiko Kamihara
发明人： Chihiro Manri , Satoshi Mitsuyama , Tomonori Mimura , Kumiko Kamihara
IPC分类号： G01N31/00 , G01N35/00 , G01N35/04
CPC分类号： G01N35/00584 , G01N35/00693 , G01N2035/00673 , G01N2035/00702 , G01N2035/0453
摘要： Accuracy control of an automatic analysis device that mixes a sample and a reagent to measure temporal change of a mixed solution is realized. A plurality of measurement point data is acquired from a reaction process of the sample and the reagent. Parameters and test values of approximate equations for approximating the plurality of measurement point data are accumulated in a storage unit. A distribution map of reference data corresponding to the parameters or the test values is created based on predetermined numbers of the parameters or the test values accumulated in the storage unit. Next, a plurality of screens for individually superimposing, on the distribution map, curved lines corresponding to a plurality of regression function candidates obtained by applying a plurality of regression functions are arranged and presented on a display screen, so as to approximate the data to the distribution map of the reference data.
摘要翻译：实现了混合样品和试剂以测量混合溶液的时间变化的自动分析装置的精度控制。从样品和试剂的反应过程获取多个测量点数据。用于近似多个测量点数据的近似等式的参数和测试值被累积在存储单元中。基于在存储单元中累积的参数或测试值的预定数量来创建与参数或测试值相对应的参考数据的分布图。接下来，在分配图上单独叠加多个屏幕，将与通过应用多个回归函数获得的多个回归函数候选对应的曲线布置并呈现在显示屏上，以将数据近似为参考数据的分布图。

17. 发明授权

US09488667B2 Automatic analyzer 有权
标题翻译：自动分析仪
公开(公告)号：US09488667B2
公开(公告)日：2016-11-08
申请号：US13318819
申请日：2010-04-12
申请人： Kumiko Kamihara , Satoshi Mitsuyama , Tomonori Mimura , Chihiro Manri
发明人： Kumiko Kamihara , Satoshi Mitsuyama , Tomonori Mimura , Chihiro Manri
IPC分类号： G01C19/00 , G01N35/00
CPC分类号： G01N35/00613 , G01N2035/0097
摘要： To change a photometric time for each item or to change a measurement time for each specimen so that time required for biochemical measurement can be reduced, an index that indicates an end of a reaction is required. Unfortunately, however, no methods have been available for determining the end of the reaction. In measuring a substance to be measured contained in a sample, a parameter in an approximate expression is calculated using a measured value that changes with time, a degree of convergence of a reaction is determined according to a degree of convergence of the parameter, and a measured value at the end of the reaction is calculated using the parameter at a point in time at which it is determined that the reaction has converged.
摘要翻译：要更改每个项目的光度时间或更改每个样品的测量时间，以便可以减少生物化学测量所需的时间，则需要指示反应结束的指标。然而，不幸的是，没有方法可用于确定反应的结束。在测定样品中含有的待测物质时，使用随时间变化的测定值来计算近似表达式中的参数，根据参数的收敛程度确定反应的收敛程度，使用在确定反应已经收敛的时间点的参数来计算反应结束时的测量值。

18. 发明授权

US09229015B2 Accuracy management method 有权
标题翻译：精准管理方法
公开(公告)号：US09229015B2
公开(公告)日：2016-01-05
申请号：US13141984
申请日：2009-11-19
申请人： Qing Li , Tomonori Mimura , Shinichi Fukuzono , Naomi Ishii
发明人： Qing Li , Tomonori Mimura , Shinichi Fukuzono , Naomi Ishii
IPC分类号： G01N35/00 , G01D18/00 , G01N35/02
CPC分类号： G01N35/00693 , G01D18/00 , G01N35/00613 , G01N35/00712 , G01N35/025 , Y10T436/10 , Y10T436/11
摘要： There is provided a comprehensive accuracy management method attained by including the steps of: displaying operation event information in time series in an accuracy management result chart or a calibration result chart on the same screen; accumulating a characteristic daily measurement value fluctuation pattern on the basis of a kind of an operation event; displaying the latest fluctuation pattern of measurement results and the daily measurement value fluctuation pattern in superposition with each other to warn of fluctuations which differ from the daily measurement value fluctuation pattern; and estimating and reporting the cause of the fluctuations.
摘要翻译：提供了一种全面的准确度管理方法，其包括以下步骤：在同一屏幕上的精度管理结果图表或校准结果图表中以时间序列显示操作事件信息; 基于操作事件的种类积累特征的日测量值波动模式; 显示测量结果的最新波动模式和每日测量值波动模式相互叠加以警告与日测量值波动模式不同的波动; 并估计和报告波动的原因。

19. 发明申请

US20140220705A1 AUTOMATED ANALYZER AND ANALYZING METHOD 有权
标题翻译：自动分析仪和分析方法
公开(公告)号：US20140220705A1
公开(公告)日：2014-08-07
申请号：US14238060
申请日：2012-09-03
申请人： Takeshi Yogi , Sakuichiro Adachi , Tomonori Mimura , Hajime Yamazaki
发明人： Takeshi Yogi , Sakuichiro Adachi , Tomonori Mimura , Hajime Yamazaki
IPC分类号： G01N33/543
CPC分类号： G01N33/54366 , G01N21/47 , G01N21/51 , G01N21/82 , G01N33/54313 , G01N35/025 , G01N2021/825 , G01N2035/0441 , G01N2035/0443 , G01N2035/0444 , G01N2800/24
摘要： An analyzer provides conditions suitable for a reagent for performing latex immunoassay with a high sensitivity using a method of measuring scattered light. Irradiation light having a wavelength in the range of 0.65 to 0.75 μm is used, and scattered light generated from a reaction solution is received at a light-receiving angle of 15° to 35° with respect to the irradiation direction during the rotational movement of the reaction container. The reagent contains latex particles the average peak particle diameter of which ranges from 0.3 μm to 0.43 μm and to which antibodies are sensitized. The reaction solution contains latex particles at a concentration at which the absorbance to irradiation light having a wavelength of 0.7 μm is 0.25 abs to 1.10 abs, and a change in the amount of scattered light caused by the aggregation of the latex particles through antigens in a sample is measured and quantified.
摘要翻译：使用测量散射光的方法，分析仪提供适合于使用高灵敏度进行乳胶免疫测定的试剂的条件。使用波长在0.65〜0.75μm范围内的照射光，从反应溶液产生的散射光以相对于照射方向为15°〜35°的受光角度被接受反应容器该试剂含有平均峰值粒径为0.3μm〜0.43μm的胶乳粒子，抗体被致敏。反应溶液含有胶乳颗粒，其浓度为具有0.7μm波长的照射光的吸光度为0.25atm至1.10abs，以及由胶乳颗粒通过抗原凝集而引起的散射光量的变化样品被测量和量化。

20. 发明申请

US20140140890A1 AUTOMATIC ANALYSIS DEVICE 有权
标题翻译：自动分析装置
公开(公告)号：US20140140890A1
公开(公告)日：2014-05-22
申请号：US14116177
申请日：2012-05-09
申请人： Sakuichiro Adachi , Tomonori Mimura , Hajime Yamazaki , Masaki Shiba
发明人： Sakuichiro Adachi , Tomonori Mimura , Hajime Yamazaki , Masaki Shiba
IPC分类号： G01N35/02
CPC分类号： G01N35/025 , G01N21/51 , G01N21/82 , G01N2021/4711 , G01N2035/0453
摘要： The automatic analysis device measures time sequential data on a scattered light amount as reaction process data, and quantitatively determines the concentration of an analyte from a change in light amount. The automatic analysis device has a function of selecting reaction process data to be used for quantitative determination from the reaction process data obtained by measurement using a plurality of light receivers at different angles. As a result of using this function, data is selected from the reaction process data obtained by measurement using the plurality of light receivers at different angles in accordance with the concentration of the analyte and whether the priority is given to high sensitivity in the case where sensitivity is prioritized or a dynamic range, and the result of the quantitative determination is displayed.
摘要翻译：自动分析装置测量作为反应过程数据的散射光量的时间序列数据，并且从光量的变化定量地确定分析物的浓度。自动分析装置具有从通过使用多个不同角度的光接收器的测量获得的反应过程数据中选择要用于定量确定的反应过程数据的功能。作为使用该功能的结果，从根据分析物的浓度以不同角度通过使用多个光接收器的测量获得的反应过程数据中选择数据，以及在灵敏度的情况下是否优先考虑高灵敏度优先或动态范围，并显示定量确定的结果。

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