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11. 发明授权

US08041982B2 Real time clock 有权
标题翻译：实时时钟
公开(公告)号：US08041982B2
公开(公告)日：2011-10-18
申请号：US12395326
申请日：2009-02-27
申请人： Sanjeeva Reddy Pindi
发明人： Sanjeeva Reddy Pindi
IPC分类号： G06F1/14
CPC分类号： G06F1/14 , G06F1/3203 , G06F1/325
摘要： Various apparatuses, methods and systems for a real time clock are disclosed herein. For example, some embodiments provide a real time clock including a clock generator having a first input connected to a clock signal and a second input connected to a time set signal. The clock generator produces a time change signal at an output of the clock generator. Counters, each adapted to track a different unit of time, are connected to the time change signal. The clock generator is adapted to generate a pulse on the time change signal for each pulse of the time set signal, and to generate separate pulses on the time change signal for consecutive pulses on the clock signal and the time set signal.
摘要翻译：这里公开了用于实时时钟的各种装置，方法和系统。例如，一些实施例提供实时时钟，其包括具有连接到时钟信号的第一输入和连接到时间设定信号的第二输入的时钟发生器。时钟发生器在时钟发生器的输出端产生时变信号。每个适用于跟踪不同时间单位的计数器连接到时间变化信号。时钟发生器适于根据时间设定信号的每个脉冲对时变信号产生脉冲，并且对时钟信号和时间设定信号上的连续脉冲在时变信号上产生单独的脉冲。

12. 发明申请

US20110195110A1 UREA COMPOUNDS USEFUL IN THE TREATMENT OF CANCER 审中-公开
标题翻译： UREA化合物可用于治疗癌症
公开(公告)号：US20110195110A1
公开(公告)日：2011-08-11
申请号：US12095611
申请日：2006-12-01
申请人： Roger Smith , Holia N. Hatoum-Mokdad , Louis David Cantin , Donald E. Bierer , Wenlang Fu , Dhanapalan Nagarathnam , Gaetan Ladouceur , Yamin Wang , Herbert Ogutu , Scot Wilhelm , Ian Taylor , Sanjeeva Reddy , Richard Gedrich , Christopher Carter , Aaron Schmitt , Xiaomei Zhang
发明人： Roger Smith , Holia N. Hatoum-Mokdad , Louis David Cantin , Donald E. Bierer , Wenlang Fu , Dhanapalan Nagarathnam , Gaetan Ladouceur , Yamin Wang , Herbert Ogutu , Scot Wilhelm , Ian Taylor , Sanjeeva Reddy , Richard Gedrich , Christopher Carter , Aaron Schmitt , Xiaomei Zhang
IPC分类号： A61K9/127 , C07D401/12 , C07D401/14 , A61K31/4439 , A61K31/506 , A61K31/444 , A61K31/4375 , A61K31/4535 , A61K38/20 , A61K33/24 , A61K38/21 , A61K33/36 , A61K39/395 , A61P35/00 , A61P35/02 , A61P35/04
CPC分类号： C07D401/12 , C07D401/14
摘要： Pyrazole urea compounds, pharmaceutical compositions which contain them and methods for treating cancer using them.
摘要翻译：吡唑脲化合物，含有它们的药物组合物和使用它们治疗癌症的方法。

13. 发明授权

US07435750B2 Method of using substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs as activators of caspases and inducers of apoptosis and the use thereof 失效
标题翻译：使用取代的3-芳基-5-芳基 - [1,2,4] - 恶二唑和类似物作为胱天蛋白酶的活化剂和凋亡诱导剂的方法及其用途
公开(公告)号：US07435750B2
公开(公告)日：2008-10-14
申请号：US11074077
申请日：2005-03-08
申请人： Sui Xiong Cai , Han-Zhong Zhang , John A. Drewe , P. Sanjeeva Reddy , Shailaja Kasibhatla , Jared Daniel Kuemmerle , Kristin P. Ollis
发明人： Sui Xiong Cai , Han-Zhong Zhang , John A. Drewe , P. Sanjeeva Reddy , Shailaja Kasibhatla , Jared Daniel Kuemmerle , Kristin P. Ollis
IPC分类号： A61K31/422 , A61K31/4245 , A61K31/443 , A61K31/4709 , A61K31/4155 , A61K31/4178 , A61K31/4025 , A61K31/381 , A61K31/341 , A61K31/519 , A61K31/4725
CPC分类号： C07D413/14 , A61K31/335 , A61K31/38 , A61K31/395 , C07D409/04 , C07D409/14 , C07D413/04 , C07D417/14 , C07D471/04
摘要： The present invention is directed to substituted 3-aryl-5-aryl-[1,2,4]-oxadiazoles and analogs thereof, represented by the Formula I: wherein Ar1, Ar3, A, B and D are defined herein. The present invention also relates to the discovery that compounds having Formula I are activators of caspases and inducers of apoptosis. Therefore, the activators of caspases and inducers of apoptosis of this invention may be used to induce cell death in a variety of clinical conditions in which uncontrolled growth and spread of abnormal cells occurs.
摘要翻译：本发明涉及由式I表示的取代的3-芳基-5-芳基 - [1,2,4] - 恶二唑及其类似物：其中Ar 1，Ar 3 A，B和D在本文中定义。本发明还涉及发现具有式I的化合物是胱天蛋白酶的活化剂和凋亡诱导剂。因此，本发明的胱天蛋白酶和细胞凋亡诱导剂的激活剂可用于在异常细胞发生不受控制的生长和扩散的各种临床病症中诱导细胞死亡。

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