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11. 发明申请

WO2012012428A2 SYSTEMS AND METHODS FOR IDENTIFYING A DISCONTINUITY IN THE BOUNDARY OF AN OBJECT IN AN IMAGE 审中-公开
标题翻译：用于识别图像中对象边界中的不连续性的系统和方法
公开(公告)号：WO2012012428A2
公开(公告)日：2012-01-26
申请号：PCT/US2011044538
申请日：2011-07-19
申请人： OPTOPO INC D B A CENTICE CORP , CHAPMAN KENNETH WAYNE , POTULURI PRASANT
发明人： CHAPMAN KENNETH WAYNE , POTULURI PRASANT
IPC分类号： A61J3/00 , B65B1/30 , G01N21/00 , G01N33/15
CPC分类号： G06Q50/22 , G06F19/3462 , G06Q10/10 , G06T7/0004 , G06T7/12 , G06T7/155 , G06T2207/10152 , G06T2207/20044 , G06T2207/20168 , G06T2207/30108 , G07F17/0092 , G07G1/0063
摘要： Machine vision is used to identify a discontinuity in the boundary of an object in an image. An image of one or more objects is captured. One or more skeletons of the one or more objects are calculated. One or more boundaries of the one or more objects are calculated. A plurality of radial lines is extended from a spine point of a skeleton to the one or more boundaries. Each radial line intersects a boundary at a radial endpoint producing a plurality of radial endpoints. For each radial endpoint an expected radial endpoint is calculated based on two or more neighboring radial endpoints. If the difference between the radial endpoint and its expected radial endpoint exceeds a threshold, a radial line including the radial endpoint is identified as a discontinuity in a boundary of an object.
摘要翻译：机器视觉用于识别图像中对象边界的不连续性。捕获一个或多个对象的图像。计算一个或多个对象的一个或多个骨架。计算一个或多个对象的一个或多个边界。多个径向线从骨架的脊点延伸到一个或多个边界。每个径向线在径向端点处的边界相交，产生多个径向端点。对于每个径向端点，基于两个或更多个相邻的径向端点来计算预期的径向端点。如果径向端点与其预期径向端点之间的差异超过阈值，则包括径向端点的径向线被标识为对象边界中的不连续性。

12. 发明申请

WO2010027761A1 SPECTRAL SIGNATURE EXTRACTION FOR DRUG VERIFICATION AND IDENTIFICATION 审中-公开
标题翻译：用于药物验证和鉴定的光谱签名提取
公开(公告)号：WO2010027761A1
公开(公告)日：2010-03-11
申请号：PCT/US2009/054836
申请日：2009-08-25
申请人： OPTOPO, INC. D/B/A CENTICE CORPORATION , POTULURI, Prasant , XUE, Ya , QI, Yuting
发明人： POTULURI, Prasant , XUE, Ya , QI, Yuting
IPC分类号： G01N21/65
CPC分类号： G06Q50/22 , G06F19/00 , G06F19/3456
摘要： Systems and methods perform signature extraction from an acquired spectrum of a pharmaceutical. An acquired spectrum of the pharmaceutical is measured using a spectrometer. The acquired spectrum is obtained from the spectrometer using a processor. A system-response function of the spectrometer is removed from the acquired spectrum using the processor. An intensity of the acquired spectrum is normalized to a predetermined scale using the processor. Fluorescence is removed from the acquired spectrum using the processor. Finally, an extracted signature of the pharmaceutical is obtained from the remainder of the acquired spectrum using the processor. If the acquired spectrum of the pharmaceutical is measured by the spectrometer through a container holding the pharmaceutical, a spectrum of the container is removed from the remainder of the acquired spectrum to produce the extracted signature of the pharmaceutical using the processor.
摘要翻译：系统和方法从药物的获得谱执行签名提取。使用光谱仪测量药物的获得谱。所获得的光谱使用处理器从光谱仪获得。使用处理器从采集的光谱中去除光谱仪的系统响应功能。使用处理器将获取的光谱的强度归一化为预定的刻度。使用处理器从所获取的光谱中除去荧光。最后，使用处理器从获取的光谱的其余部分获得药物的提取的签名。如果通过光谱仪通过容纳药物的容器测量所获得的药物谱，则从获得的光谱的其余部分中除去容器的光谱，以使用处理器产生提取的药物的特征。

13. 发明申请

WO2008063681A3 SPATIALLY PATTERNED SUBSTRATES FOR CHEMICAL AND BIOLOGICAL SENSING 审中-公开
标题翻译：用于化学和生物传感的空间图案
公开(公告)号：WO2008063681A3
公开(公告)日：2009-04-16
申请号：PCT/US2007061705
申请日：2007-02-06
申请人： OPTOPO INC D B A CENTICE CORP , BRADY DAVID , SULLIVAN MICHAEL , POTULURI PRASANT
发明人： BRADY DAVID , SULLIVAN MICHAEL , POTULURI PRASANT
IPC分类号： G01J3/44 , G01J3/00 , G01J3/443
CPC分类号： G01N21/658 , G01N21/31 , G01N21/554 , G01N21/6452 , G01N21/648 , G01N2021/317 , G01N2021/6417 , G01N2201/06113 , G01N2201/062
摘要： A system and method are provided for imaging a test substrate having a test surface that is configured to enable spectroscopic detection of one or more chemical or biological species, wherein the test surface includes a testing site disposed thereon according to a predetermined spatial pattern. The test substrate is provided in an image plane or a Fourier Transform plane of the sensor. The invention provides high throughput and high spectral resolution.
摘要翻译：提供了一种系统和方法，用于对具有被配置为使得能够对一种或多种化学或生物物种进行光谱检测的测试表面的测试基底成像，其中所述测试表面包括根据预定空间图案设置在其上的测试位置。测试基板设置在传感器的图像平面或傅里叶变换平面中。本发明提供高通量和高光谱分辨率。

14. 发明申请

WO2008064278A3 A METHOD AND APPARATUS FOR RECONSTRUCTING OPTICAL SPECTRA IN A STATIC MULTIMODE MULTIPLEX SPECTROMETER 审中-公开
公开(公告)号：WO2008064278A3
公开(公告)日：2008-05-29
申请号：PCT/US2007/085323
申请日：2007-11-21
申请人： OPTOPO, INC DBA CENTICE CORPORATION , POTULURI, Prasant , GHOFRANI, Mehran , CULL, Evan , STRANZL, John
发明人： POTULURI, Prasant , GHOFRANI, Mehran , CULL, Evan , STRANZL, John
IPC分类号： G01J3/42
摘要： The static MMS spectral reconstruction process is optimized using algorithmic methods. Because the static MMS encodes spectral information across the detector plane in a highly non-local way, optical errors have a non-local effect on the reconstruction which introduces noise and errors at regions throughout the spectral range. Mathematical signal processing techniques are used to condition and de-convolve the spectral image to compensate for non-ideal system behavior. Spectral signal-to-noise and accuracy are both improved, while the inherent resolution and etendue advantages of the static MMS technique are retained.

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