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    • 12. 发明申请
    • Chemical structure-insensitive method and apparatus for dissociating ions
    • 用于离子离子化学结构不敏感的方法和装置
    • US20080217527A1
    • 2008-09-11
    • US11715199
    • 2007-03-07
    • Mingda Wang
    • Mingda Wang
    • B01D59/44
    • H01J49/426H01J49/005
    • In a method for exciting a precursor ion in an ion trap, the ion is trapped in a nonlinear trapping field that includes a quadrupolar field and a multipole field. The quadrupolar field is generated by applying a radio-frequency (RF) trapping voltage to the ion trap at a trapping amplitude and trapping frequency. A supplemental alternating-current (AC) voltage is applied to the ion trap at a supplemental amplitude and supplemental frequency. The supplemental amplitude is low enough to prevent ejection of the ion from the ion trap, and the supplemental frequency differs from the secular frequency of the ion by an offset amount. One or more operating parameters of the ion trap are adjusted, such that the ion absorbs energy from the supplemental field sufficient to undergo collision-induced dissociation (CID) without being in resonance with the supplemental field.
    • 在用于在离子阱中激发前体离子的方法中,离子被捕获在包括四极场和多极场的非线性捕获场中。 通过以捕获幅度和捕获频率向离子阱施加射频(RF)捕获电压来产生四极场。 补充的交流(AC)电压以补充的幅度和补充频率施加到离子阱。 辅助振幅足够低以防止离子从离子阱中喷射,并且补充频率与离子的长期频率不同,具有偏移量。 调整离子阱的一个或多个操作参数,使得离子从补充场吸收足以进行碰撞诱导解离(CID)的能量,而不与补充场共振。
    • 16. 发明授权
    • Multipole ion transport apparatus and related methods
    • 多极离子输送装置及相关方法
    • US08124930B2
    • 2012-02-28
    • US12479614
    • 2009-06-05
    • Mingda Wang
    • Mingda Wang
    • H01J49/00
    • H01J49/063
    • An ion transport apparatus includes an ion entrance end, an ion exit end, and electrodes arranged along a longitudinal axis from the ion entrance end toward the ion exit end. The electrodes are configured for applying an RF electrical field that varies along the longitudinal axis such that at the ion entrance end, the RF electrical field comprises a major first multipole component of 2n1 poles where n1≧3/2, and at the ion exit end the RF electrical field comprises predominantly a second multipole component of 2n2 poles where n2≧3/2 and n2
    • 离子传输装置包括离子入口端,离子出口端和沿着从离子入口端朝向离子出口端的纵向轴线布置的电极。 电极被配置为施加沿着纵向轴线变化的RF电场,使得在离子入口端,RF电场包括2n1极的主要第一多极分量,其中n1≥3/ 2,并且在离子出口端 RF电场主要包括2n2极的第二多极分量,其中n2≥3/ 2和n2
    • 20. 发明授权
    • Chemical structure-insensitive method and apparatus for dissociating ions
    • 用于离子离子化学结构不敏感的方法和装置
    • US07842918B2
    • 2010-11-30
    • US11715199
    • 2007-03-07
    • Mingda Wang
    • Mingda Wang
    • B01D59/44
    • H01J49/426H01J49/005
    • In a method for exciting a precursor ion in an ion trap, the ion is trapped in a nonlinear trapping field that includes a quadrupolar field and a multipole field. The quadrupolar field is generated by applying a radio-frequency (RF) trapping voltage to the ion trap at a trapping amplitude and trapping frequency. A supplemental alternating-current (AC) voltage is applied to the ion trap at a supplemental amplitude and supplemental frequency. The supplemental amplitude is low enough to prevent ejection of the ion from the ion trap, and the supplemental frequency differs from the secular frequency of the ion by an offset amount. One or more operating parameters of the ion trap are adjusted, such that the ion absorbs energy from the supplemental field sufficient to undergo collision-induced dissociation (CID) without being in resonance with the supplemental field.
    • 在用于在离子阱中激发前体离子的方法中,离子被捕获在包括四极场和多极场的非线性捕获场中。 通过以捕获幅度和捕获频率向离子阱施加射频(RF)捕获电压来产生四极场。 补充的交流(AC)电压以补充的幅度和补充频率施加到离子阱。 辅助振幅足够低以防止离子从离子阱中喷射,并且补充频率与离子的长期频率不同,具有偏移量。 调整离子阱的一个或多个操作参数,使得离子从补充场吸收足以进行碰撞诱导解离(CID)的能量,而不与补充场共振。