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11. 发明授权

US06527725B1 Blood pressure estimating apparatus 失效
标题翻译：血压估计装置
公开(公告)号：US06527725B1
公开(公告)日：2003-03-04
申请号：US09768265
申请日：2001-01-25
申请人： Hidekatsu Inukai , Akihiro Yokozeki , Keizoh Kawaguchi , Kiyoyuki Narimatsu
发明人： Hidekatsu Inukai , Akihiro Yokozeki , Keizoh Kawaguchi , Kiyoyuki Narimatsu
IPC分类号： A61B500
CPC分类号： A61B5/02225 , A61B5/02125 , A61B5/0225 , A61B5/024 , A61B5/0285
摘要： An apparatus for estimating a blood pressure of a living subject, including a measuring device which iteratively measures a blood pressure of the subject, a first device for obtaining first information relating to velocity of propagation of pulse wave, a second device for obtaining at least one of second information relating to heart rate and third information relating to area defined by volume pulse wave, a memory which stores groups of information each group of which includes the blood pressure, the first information, and at least one of the second information and the third information, a determining device for determining an expression representing a relationship between (A) blood pressure, and (B1) first information and (B2) at least one of (B21) second information and (B22) third information, and having a first coefficient for the first information, at least one second coefficient for at least one of the second and third information, and a constant, the determining device determining the coefficients and constant of the expression by applying a multiple regression analysis to more than a predetermined number of groups of information last stored in the memory, the predetermined number being equal to a total number of the coefficients and the constant, and an estimating device for successively estimating, according to the expression, a blood pressure of the subject based on each first information and at least one of each second information and each third information.
摘要翻译：一种用于估计活体的血压的装置，包括迭代地测量对象的血压的测量装置，用于获得与脉搏波传播速度有关的第一信息的第一装置，用于获得至少一个关于心率的第二信息和与体积脉搏波所定义的区域相关的第三信息;存储器，其存储每组包括血压的信息组，第一信息以及第二信息和第三信息中的至少一个信息，用于确定表示（A）血压和（B1）第一信息之间的关系的表达式的确定装置，（B2）（B21）第二信息和（B22）第三信息中的至少一个，并且具有第一系数对于第一信息，对于第二和第三信息中的至少一个信息的至少一个第二系数，以及常数，确定装置确定通过对多于一个预定数量的上一次存储在存储器中的信息组进行多重回归分析，得到系数和表达式的常数，该预定数量等于系数和常数的总数，以及估计装置用于根据表达式基于每个第一信息和每个第二信息和每个第三信息中的至少一个依次估计对象的血压。

12. 发明授权

US06283922B1 Blood pressure monitor 失效
标题翻译：血压监测仪
公开(公告)号：US06283922B1
公开(公告)日：2001-09-04
申请号：US09397666
申请日：1999-09-16
申请人： Masami Goto , Hideo Nishibayashi , Kiyoyuki Narimatsu , Akihiro Yokozeki
发明人： Masami Goto , Hideo Nishibayashi , Kiyoyuki Narimatsu , Akihiro Yokozeki
IPC分类号： A61B500
CPC分类号： A61B5/02225 , A61B5/02116 , A61B5/02125 , A61B5/0225
摘要： A blood pressure monitor including a cuff, a pressure sensor which detects a pressure in the cuff, a pressure regulating device which increases the pressure of the cuff, a pulse-amplitude determining device for determining an amplitude of each of pulses of a pulse wave which are produced in the cuff and detected by the pressure sensor while the cuff pressure is increased, a candidate determining device for determining, as a diastolic BP candidate, a pressure of the cuff which is detected by the pressure sensor and which corresponds to an amplitude of a first pulse of the pulses determined by the pulse-amplitude determining device, by judging whether the amplitude of the first pulse is not greater than a reference value which is smaller than an amplitude of at least one second pulse of the pulses, by a predetermined proportion of the amplitude of the second pulse, the amplitude of the second pulse being determined by the pulse-amplitude determining device after the amplitude of the first pulse is determined, and a BP determining device for determining, as a monitor diastolic BP value, the cuff pressure corresponding to the amplitude of the first pulse, when the candidate determining device determines, as the diastolic BP candidate, the cuff pressure corresponding to the amplitude of the first pulse, with respect to a predetermined number of the one or more second pulses.
摘要翻译：一种血压监视器，包括袖带，压力传感器，其检测袖带内的压力;压力调节装置，其增加袖带的压力;脉冲幅度确定装置，用于确定脉搏波的每个脉冲的幅度，在袖带中产生，并且在袖带压力增加时由压力传感器检测;候选确定装置，用于确定由压力传感器检测的袖带的压力作为舒张BP候选，并且对应于由脉冲幅度确定装置确定的脉冲的第一脉冲，通过判断第一脉冲的幅度是否不大于比脉冲的至少一个第二脉冲的振幅小的参考值，预定的脉冲第二脉冲的振幅的比例，第二脉冲的振幅由脉冲振幅确定装置确定，在第一脉冲的振幅之后 t脉冲，以及BP判定装置，当所述候选判定装置判定为与所述第一脉冲的振幅对应的所述袖带压时，作为所述监视器舒张BP值，确定与所述第一脉冲的振幅对应的袖带压，相对于一个或多个第二脉冲的预定数量的第一脉冲的幅度。

13. 发明授权

US06251081B1 Blood-pressure monitoring apparatus 失效
标题翻译：血压监测仪
公开(公告)号：US06251081B1
公开(公告)日：2001-06-26
申请号：US09392236
申请日：1999-09-08
申请人： Kiyoyuki Narimatsu
发明人： Kiyoyuki Narimatsu
IPC分类号： A61B502
CPC分类号： A61B5/02125 , A61B5/022
摘要： A blood-pressure monitoring apparatus including a measuring device which periodically measures a blood-pressure value of a living subject at a predetermined period, and a predicting device or circuit which predicts, based on the blood-pressure values measured by the measuring device, a blood-pressure value of the living subject at a time later by a predetermined time than a time when the last one of the blood-pressure values is measured by the measuring device.
摘要翻译：一种血压监视装置，包括周期性地测量生物体在预定时间段的血压值的测量装置，以及预测装置或电路，其基于由测量装置测量的血压值，生物体的血压值比通过测定装置测定最后一个血压值的时间更长的预定时间。

14. 发明授权

US5590661A Blood pressure measuring apparatus 失效
标题翻译：血压测量仪
公开(公告)号：US5590661A
公开(公告)日：1997-01-07
申请号：US282230
申请日：1994-07-29
申请人： Kenji Ohmori , Kiyoyuki Narimatsu , Ikuo Kobayashi
发明人： Kenji Ohmori , Kiyoyuki Narimatsu , Ikuo Kobayashi
IPC分类号： A61B5/022 , A61B5/02
CPC分类号： A61B5/022
摘要： A blood pressure measuring apparatus including a surface-pressure sensor having a pressure sensing element in a press surface thereof to detect a pressure at the press surface pressed on subject's body surface and generate a pressure signal representing the detected surface pressure, the pressure signal containing successive pulses representing a pressure pulse wave produced from subject's artery, a pressing device which presses the sensor against the artery via the body surface, a control device which changes the pressing force of the pressing device applied to the sensor, to partially flatten the artery, and obtains the successive pulses of the pressure signal during the changing of the pressing force, a first determining device for determining, in a two-dimensional orthogonal coordinate system, a first straight line approximating a level portion of (a) an upper-peak curve connecting respective upper-peak magnitudes of the successive pulses of the pressure signal and/or (b) a lower-peak curve connecting respective lower-peak magnitudes of the successive pulses, a second determining device for determining a second straight line approximating an increasing portion of (a) the upper-peak curve and/or (b) the lower-peak curve, and a blood pressure determining device for determining a systolic and/or a diastolic blood pressure of the subject based on an intersecting point of the first and second straight lines.
摘要翻译：一种血压测量装置，包括：表面压力传感器，其在其压力表面具有压力感测元件，用于检测按压在被检体体表上的压力表面的压力，并产生表示检测到的表面压力的压力信号，所述压力信号包含连续表示从受试者的动脉产生的压力脉冲波的脉冲，通过身体表面将传感器压靠在动脉上的按压装置，改变施加到传感器的按压装置的按压力以使动脉部分平坦化的控制装置，以及在压力变化期间获得压力信号的连续脉冲;第二确定装置，用于在二维正交坐标系中确定第一直线，其接近（a）连接的上峰曲线的电平部分压力信号的连续脉冲的相应上峰值幅度和/或（b）较低p 连接连续脉冲的相应较低峰值幅度的ak曲线，用于确定接近（a）上峰曲线和/或（b）下峰曲线的增加部分的第二直线的第二确定装置，以及用于基于第一和第二直线的相交点来确定受试者的收缩压和/或舒张压的血压测定装置。

15. 发明授权

US5467771A Pulse wave sensor 失效
标题翻译：脉波传感器
公开(公告)号：US5467771A
公开(公告)日：1995-11-21
申请号：US307445
申请日：1994-09-19
申请人： Kiyoyuki Narimatsu , Norio Kawamura
发明人： Kiyoyuki Narimatsu , Norio Kawamura
IPC分类号： A61B5/0245 , A61B5/021 , A61B5/00
CPC分类号： A61B5/021 , A61B5/02116 , A61B2562/0247 , A61B2562/043
摘要： A pressure pulse wave sensor for detecting a pressure pulse wave produced from an arterial vessel of a living subject in synchronism with heartbeat of the subject, the sensor having a press surface adapted to be pressed on a body surface of the subject, a protruding portion protruding from the press surface and having a top surface, and at least one pressure sensing element provided in the top surface of the protruding portion, for detecting the pressure pulse wave produced from the arterial vessel, the top surface of the protruding portion being covered with a resilient protective layer, the pulse wave sensor further comprising a hard member which surrounds the protruding portion such that a top end of the hard member is substantially flush with the resilient protective layer covering the top surface of the protruding portion.
摘要翻译：一种压力脉搏波传感器，用于与受检者的心跳同步地检测从活体的动脉血管产生的压力脉搏波，所述传感器具有适于被压在被检体的身体表面上的按压面，突出部突出从所述按压面上具有顶面，以及设置在所述突出部的上表面的至少一个压力感测元件，用于检测从所述动脉血管产生的压力脉搏波，所述突出部的上表面覆盖有所述脉搏波传感器还包括围绕所述突出部分的硬构件，使得所述硬构件的顶端与覆盖所述突出部分的顶表面的所述弹性保护层基本齐平。

16. 发明授权

US07361148B2 Cuff volumetric pulse wave obtaining apparatus, cuff volumetric pulse wave analyzing apparatus, pressure pulse wave obtaining apparatus, and pressure pulse wave analyzing apparatus 有权
标题翻译：袖带体积脉波获取装置，袖带体积脉波分析装置，压力脉波获取装置和压力脉波分析装置
公开(公告)号：US07361148B2
公开(公告)日：2008-04-22
申请号：US10756408
申请日：2004-01-14
申请人： Kiyoyuki Narimatsu
发明人： Kiyoyuki Narimatsu
IPC分类号： A61B5/02
CPC分类号： A61B5/022 , A61B5/0275 , A61B5/4035 , A61B5/4041 , A61B7/04
摘要： A subject evaluation value measuring apparatus 10, functioning as a cuff volumetric pulse wave obtaining apparatus, includes a pulse wave determining device (i.e., a cuff volumetric pulse wave determining device) 52 that determines, using an inverse transfer function 1H(f), stored in a ROM (i.e., an inverse transfer function memory) 42, that corresponds to a pre-determined transfer function H(f) between input, i.e., pressure pulsation produced in a cuff 20, and output, i.e., pressure pulsation detected by a pressure sensor 24, a no-delay cuff volumetric pulse wave PK(t) having substantially no delay of transmission, based on an actual cuff pulse wave signal SM outputted by the pressure sensor 24. The thus determined cuff volumetric pulse wave PK(t) is free of waveform distortion and accordingly enjoys high accuracy.
摘要翻译：用作袖带体积脉波获取装置的被检体评价值测定装置10包括使用逆传递函数1H（f）存储的脉波确定装置（即，袖带体积脉波确定装置）52 在对应于输入之间的预定传递函数H（f）的ROM（即，逆传递函数存储器）42中，即在袖带20中产生的压力脉动与输出之间，即由压力传感器24，基于由压力传感器24输出的实际袖带脉波信号SM，基本上没有发送延迟的无延迟袖带体积脉搏波P（K）。如此确定的袖带体积脉搏波P（t）没有波形失真，因此具有高精度。

17. 发明授权

US07097621B2 Filter for use with pulse-wave sensor and pulse wave analyzing apparatus 失效
标题翻译：滤波器用于脉波传感器和脉波分析仪
公开(公告)号：US07097621B2
公开(公告)日：2006-08-29
申请号：US10760582
申请日：2004-01-21
申请人： Kiyoyuki Narimatsu , Akira Tampo , Takashi Honda
发明人： Kiyoyuki Narimatsu , Akira Tampo , Takashi Honda
IPC分类号： A61B5/00
CPC分类号： A61B5/0285 , A61B5/022
摘要： A pulse wave analyzing apparatus including a cuff 12 for detecting a pulse wave from a living subject, a pressure sensor 16 for converting the pulse wave detected by the cuff 12, into an electric signal, i.e., a pulse wave signal SM, a plurality of band-pass filters 62 (BPF(1), BPF(2), . . . , BPF(n)) that have respective low-side cuff-off frequency bands differing from each other and each receive the pulse wave signal SM, a provisional rising point determining device 64 for determining respective times PS of respective provisional rising points of respective pulse waves represented by respective secondary pulse wave signals SM2 that have passed through the band-pass filters 62, and a proper rising point determining device 66 for comparing the respective times PS of respective provisional rising points with each other and thereby determining a time AS of a proper rising point based on the respective times PS of respective provisional rising points.
摘要翻译：一种脉波分析装置，包括用于检测来自活体的脉搏波的袖带12，将由袖带12检测出的脉搏波转换成电信号的压力传感器16，即脉波信号SM，多个带通滤波器62（BPF（1），BPF（2），...，BPF（n）），它们各自具有彼此不同的低侧克隆截止频带，并且各自接收脉波信号SM，a 临时上升点确定装置64，用于确定由通过带通滤波器62的各个辅助脉冲波信号SM 2表示的各个脉搏波的各个临时上升点的各个时间PS，以及用于比较的适当的上升点确定装置66 相应的临时上升点的时间PS，从而基于各个临时上升点的各个时间PS来确定适当上升点的时间AS。

18. 发明授权

US06976966B2 Arteriosclerosis evaluating apparatus 失效
标题翻译：动脉硬化评估仪
公开(公告)号：US06976966B2
公开(公告)日：2005-12-20
申请号：US10724086
申请日：2003-12-01
申请人： Kiyoyuki Narimatsu
发明人： Kiyoyuki Narimatsu
IPC分类号： A61B5/02 , A61B5/022 , A61B5/0245
CPC分类号： A61B5/022
摘要： An arteriosclerosis evaluating apparatus for evaluating an arteriosclerosis of a living subject based on a form of a pulse wave detected from the subject, the apparatus including an inflatable cuff which is adapted to be worn on a body portion of the subject, a cuff-pressure changing device which changes a pressure in the cuff, a cuff-pulse-wave detecting device which detects a cuff pulse wave as a pressure oscillation that is transmitted from the subject to the cuff, and an output device which outputs the cuff pulse wave detected by the cuff-pulse-wave detecting device in a state in which the pressure of the cuff is made higher than a systolic blood pressure of the body portion of the subject by the cuff-pressure changing device.
摘要翻译：一种动脉硬化评估装置，其用于根据从被检体检测出的脉搏波的形式来评价活体的动脉硬化，所述装置包括适于佩戴在被检体的身体部位的充气袖带，袖带压变化改变袖带压力的装置，检测袖带脉波作为从被检体发送到袖带的压力振荡的袖带脉波检测装置，以及输出装置，其输出由袖口检测到的袖带脉波袖带脉波检测装置，其通过袖带压力改变装置使袖带的压力高于被检体的身体部分的收缩压。

19. 发明授权

US06969355B2 Arteriostenosis diagnosing apparatus 失效
标题翻译：动脉粥样硬化诊断仪
公开(公告)号：US06969355B2
公开(公告)日：2005-11-29
申请号：US10780574
申请日：2004-02-19
申请人： Kiyoyuki Narimatsu
发明人： Kiyoyuki Narimatsu
IPC分类号： A61B5/02 , A61B5/021 , A61B5/022 , A61B5/0245 , A61B5/0285
CPC分类号： A61B5/0285 , A61B5/021 , A61B5/02125
摘要： An arteriostenosis diagnosing apparatus which measures an ankle blood pressure at an ankle 12 of a patient and a brachium blood pressure at a brachium 14, so that the measured ankle and brachium blood pressure values are used to calculate an ankle and brachium blood pressure index ABI, and additionally measures a first pulse wave propagation velocity PWV1 with respect to the ankle 12 as a first measuring point and the brachium 14 as a second measuring point, and a second pulse wave propagation velocity PWV2 with respect to the patient's heart and the brachium 14. The arteriostenosis diagnosing apparatus includes an arteriostenosis judging device 100 which judges, even if the index ABI may fall in a prescribed normal range or a prescribed alert range and the first velocity PWV1 falls in a prescribed normal range, that there is a possibility that an inferior limb including the ankle 12 at which the ankle blood pressure has been measured, may have arteriostenosis, if the second velocity PWV2 falls in a prescribed abnormal range.
摘要翻译：一种动脉狭窄诊断装置，其测量患者脚踝12处的踝血压和胎ium 14处的肱骨血压，使得测量的踝和肱高血压值用于计算踝和肱高血压指数ABI，并且另外测量相对于作为第一测量点的脚踝12的第一脉搏波传播速度PWV 1和作为第二测量点的臂14和相对于患者心脏和肱二头体的第二脉搏波传播速度PWV 2 14。动脉狭窄诊断装置包括：动脉狭窄判断装置100，即使指标ABI可能落在规定的正常范围或规定的警报范围内，并且第一速度PWV 1落在规定的正常范围内，则存在以下可能性：如果第二速度PWV 2处于规定的异常范围，则包括测量了踝部血压的脚踝12的下肢可能具有动脉狭窄。

20. 发明授权

US06843772B2 Inferior-and-superior-limb blood-pressure-index measuring apparatus 失效
标题翻译：下肢血压指数测定装置
公开(公告)号：US06843772B2
公开(公告)日：2005-01-18
申请号：US10300824
申请日：2002-11-21
申请人： Tomohiro Nunome , Kiyoyuki Narimatsu , Toshihiko Ogura
发明人： Tomohiro Nunome , Kiyoyuki Narimatsu , Toshihiko Ogura
IPC分类号： A61B5/022 , A61B5/0245 , A61B5/0285 , A61B5/02
CPC分类号： A61B5/02116 , A61B5/022 , A61B5/0285
摘要： An apparatus for measuring an inferior-and-superior-limb blood-pressure index of a patient, including an inferior-limb blood-pressure measuring device, a superior-limb blood-pressure measuring device, an index determining device for determining the inferior-and-superior-limb blood-pressure index, based on a blood pressure of an inferior limb measured by the inferior-limb blood-pressure measuring device and a blood pressure of a superior limb measured by the superior-limb blood-pressure measuring device, an inferior-limb-pulse-wave-propagation-velocity-related-information, obtaining device which obtains inferior-limb-pulse-wave-propagation-velocity-related information, an upper-half-body-pulse-wave-propagation-velocity-related-information obtaining device which obtains upper-half-body-pulse-wave-propagation-velocity-related information, and an evaluation-information obtaining device for obtaining, based on the inferior-limb-pulse-wave-propagation-velocity-related information and the upper-half-body-pulse-wave-propagation-velocity-related information, evaluation information that is related to evaluation of reliability of the inferior-and superior-limb blood-pressure index.
摘要翻译：一种用于测量患者的下肢和上肢血压指数的装置，包括下肢血压测量装置，上肢血压测量装置，用于确定下肢血压的指标确定装置，基于由下肢血压测定装置测定的下肢血压和上肢血压测定装置测定的上肢血压，测定上肢血压指数，下肢脉搏波传播速度相关信息获取装置，其获得下肢脉搏波传播速度相关信息，上半身脉搏波传播速度获取上半身脉搏波传播速度相关信息的相关信息获取装置，以及基于下肢脉搏波传播速度相关信息的评估信息获取装置，相关信息和upp 呃半体脉搏波传播速度相关信息，与下肢和上肢血压指数的可靠性的评价相关的评价信息。

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