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    • 11. 发明授权
    • BDNF facilitation of oocyte, zygote and pre-implantation embryo maturation
    • BDNF促进卵母细胞,合子和植入前胚胎成熟
    • US07763462B2
    • 2010-07-27
    • US11762606
    • 2007-06-13
    • Kazuhiro KawamuraAaron J. W. HsuehSabine M. Mulders
    • Kazuhiro KawamuraAaron J. W. HsuehSabine M. Mulders
    • C12N5/00A61B17/43
    • C12N5/0609C12N2501/13C12N2517/10
    • Compositions and methods are provided for enhancing the survival and promoting the maturation of mammalian oocytes, zygotes and preimplantation embryos. BDNF or BDNF agonists may be administered to an individual, or to cells in vitro, to enhance cellular maturation, embryo growth and fertilization. Accordingly, compositions comprising BDNF are herein presented for use in promoting in vivo oocyte maturation as well as for use as a component in culture media for promoting preimplantation maturation of zygotes and embryos, for instance, for use with in vitro fertilization procedures and for the production of stem cells. Additionally, compounds that interfere with the binding of BDNF to its receptor may be administered to an individual to prevent oocyte maturation, thereby acting as a contraceptive. The BNDF receptor, TrkB, and BDNF also find use in the screening and design of agonists and antagonists for use in the methods of the invention.
    • 提供组合物和方法用于增强哺乳动物卵母细胞,合子和植入前胚胎的存活和促进成熟。 BDNF或BDNF激动剂可以在体外施用于个体或细胞,以增强细胞成熟,胚胎生长和受精。 因此,本文提供了包含BDNF的组合物用于促进体内卵母细胞成熟以及用作培养基中的组分,用于促进受精卵和胚胎的植入前成熟,例如用于体外受精程序和用于生产 的干细胞。 此外,干扰BDNF与其受体的结合的化合物可以施用于个体以防止卵母细胞成熟,从而起避孕作用。 BNDF受体,TrkB和BDNF也用于筛选和设计用于本发明方法的激动剂和拮抗剂。
    • 12. 发明申请
    • INFORMATION PROCESSING DEVICE, INFORMATION PROCESSING METHOD AND PROGRAM
    • 信息处理设备,信息处理方法和程序
    • US20100153065A1
    • 2010-06-17
    • US12711255
    • 2010-02-24
    • Kazuhiro KAWAMURATsuyoshi MoriyaYasutoshi Umehara
    • Kazuhiro KAWAMURATsuyoshi MoriyaYasutoshi Umehara
    • G06F15/00G06F17/18
    • G05B23/024H01L22/20H01L2924/0002H01L2924/00
    • An information processing device includes a first input receiving unit, a second input receiving unit, a window function processing unit, a correlation calculating unit, and an output unit. The first input receiving unit is configured to receive first information including a first time-series data related to a semiconductor process. The second input receiving unit is configured to receive second information including a second time-series data related to the semiconductor process. The window function processing unit is configured to retrieve window acquiring information from the first information during an intended period using a window function. The correlation calculating unit is configured to calculate a cross-correlation function between the window acquiring information retrieved by the window function processing unit and the second information. The output unit is configured to output information corresponding to the cross-correlation function calculated by the correlation calculating unit.
    • 信息处理装置包括第一输入接收单元,第二输入接收单元,窗函数处理单元,相关计算单元和输出单元。 第一输入接收单元被配置为接收包括与半导体处理相关的第一时间序列数据的第一信息。 第二输入接收单元被配置为接收包括与半导体处理相关的第二时间序列数据的第二信息。 窗口功能处理单元被配置为使用窗口函数在预期期间从第一信息检索窗口获取信息。 相关计算单元被配置为计算由窗函数处理单元检索的窗口获取信息与第二信息之间的互相关函数。 输出单元被配置为输出与由相关计算单元计算的互相关函数相对应的信息。
    • 13. 发明授权
    • Method of vitrifying high-level radioactive liquid waste
    • 玻璃化高放射性废液的方法
    • US5530174A
    • 1996-06-25
    • US520786
    • 1995-08-30
    • Kazuhiro KawamuraMasayuki YoneyaKenichi Sasage
    • Kazuhiro KawamuraMasayuki YoneyaKenichi Sasage
    • G21F9/16G21F9/30G21F9/00
    • G21F9/305
    • A method of vitrifying a high-level radioactive liquid waste comprising removing a precipitate composed mainly of Mo and Zr from the high-level liquid waste, mixing the resulting high-level liquid waste with a raw glass material having a chemical composition wherein the B.sub.2 O.sub.3 /SiO.sub.2, ZnO/Li.sub.2 O and Al.sub.2 O.sub.3 /Li.sub.2 O ratios are at least 0.41, at least 1.00 and at least 2.58, respectively, and melt-solidifying the mixture to thereby form a vitrified waste. By using such a raw glass material, there can be obtained a vitrifled waste having the waste content of about 45% by oxide weight in which the same leaching rate as that of a conventional vitrified waste having the waste content of 25% by oxide weight is ensured without suffering from yellow phase separation.
    • 一种对高级放射性废液进行玻璃化的方法,包括从高级废液中除去主要由Mo和Zr组成的沉淀物,将所得高级废液与具有化学组成的原料玻璃材料混合,其中B 2 O 3 / SiO 2,ZnO / Li 2 O和Al 2 O 3 / Li 2 O比分别为至少0.41,至少1.00和至少2.58,并将混合物熔融固化,从而形成玻璃化废物。 通过使用原料玻璃材料,可以得到废氧含量为约45%的玻璃化废物,其氧化物重量与通过氧化物重量为25%的废物含量相同的常规玻璃化废物的浸出率相同 确保没有黄相分离。
    • 15. 发明申请
    • Facilitation of Oocyte, Zygote and Pre-Implantation Embryo Maturation
    • 促进卵母细胞,合子和植入胚胎成熟
    • US20110052599A1
    • 2011-03-03
    • US12818055
    • 2010-06-17
    • Kazuhiro KawamuraAaron J.W. HsuehSabine M. Mulders
    • Kazuhiro KawamuraAaron J.W. HsuehSabine M. Mulders
    • A61K39/395C12N5/075A61K38/18A61K31/55A61K31/7052C12Q1/02A61P15/08A61B17/43
    • C12N5/0609C12N2501/13C12N2517/10
    • Compositions and methods are provided for enhancing the survival and promoting the maturation of mammalian oocytes, zygotes and preimplantation embryos. BDNF or BDNF agonists may be administered to an individual, or to cells in vitro, to enhance cellular maturation, embryo growth and fertilization. Accordingly, compositions comprising BDNF are herein presented for use in promoting in vivo oocyte maturation as well as for use as a component in culture media for promoting preimplantation maturation of zygotes and embryos, for instance, for use with in vitro fertilization procedures and for the production of stem cells. Additionally, compounds that interfere with the binding of BDNF to its receptor may be administered to an individual to prevent oocyte maturation, thereby acting as a contraceptive. The BNDF receptor, TrkB, and BDNF also find use in the screening and design of agonists and antagonists for use in the methods of the invention.
    • 提供组合物和方法用于增强哺乳动物卵母细胞,合子和植入前胚胎的存活和促进成熟。 BDNF或BDNF激动剂可以在体外施用于个体或细胞,以增强细胞成熟,胚胎生长和受精。 因此,本文提供了包含BDNF的组合物用于促进体内卵母细胞成熟以及用作培养基中的组分,用于促进受精卵和胚胎的植入前成熟,例如用于体外受精程序和用于生产 的干细胞。 此外,干扰BDNF与其受体的结合的化合物可以施用于个体以防止卵母细胞成熟,从而起避孕作用。 BNDF受体,TrkB和BDNF也用于筛选和设计用于本发明方法的激动剂和拮抗剂。
    • 16. 发明申请
    • SEMICONDUCTOR INTEGRATED CIRCUIT
    • 半导体集成电路
    • US20080191553A1
    • 2008-08-14
    • US12016579
    • 2008-01-18
    • Kazuhiro KAWAMURA
    • Kazuhiro KAWAMURA
    • H02J1/00H02J3/14
    • G09G3/296G09G3/293G09G2320/0223G09G2330/06G09G2360/16H02M3/07H02M2001/009Y10T307/406
    • A semiconductor integrated circuit for driving a display such as a plasma display has a plurality of output bit circuits each including a latch circuit, a comparator circuit comparing the state of the latch circuit output for its own output bit circuit with the state of the latch circuit output for adjacent output bit circuits on both sides and also comparing the result of this comparison with the result of a comparison for the next inputted data, and a storage circuit holding these results. When the comparator circuit detects that the states of the outputs of all three output bit circuits are continuously the same, the output rise or fall is controlled by output transistors so as to be slow. This enables the output state transition to have a specified time duration regardless of the magnitude of the load, to reduce electromagnetic noise.
    • 用于驱动诸如等离子体显示器的显示器的半导体集成电路具有多个输出位电路,每个输出位电路包括锁存电路,比较器电路将其自己的输出位电路的锁存电路输出的状态与锁存电路的状态进行比较 输出两侧的相邻输出位电路,并且还将该比较的结果与下一个输入数据的比较结果进行比较,以及保存这些结果的存储电路。 当比较器电路检测到所有三个输出位电路的输出的状态连续相同时,输出上升或下降由输出晶体管控制得较慢。 这使得输出状态转换具有指定的持续时间,而不管负载的大小,以减少电磁噪声。
    • 17. 发明申请
    • Heat treatment apparatus and method of calibrating the apparatus
    • 热处理装置及其校准方法
    • US20070195853A1
    • 2007-08-23
    • US10561976
    • 2004-07-01
    • Youngchul ParkKazuhiro KawamuraYuichi Takenaga
    • Youngchul ParkKazuhiro KawamuraYuichi Takenaga
    • G01K15/00
    • C23C16/52C23C16/46H01L21/67103H01L21/67248
    • The present invention provides precise temperature estimation in a heat treatment apparatus that estimates temperatures of process objects by using a thermal model and performs a heat treatment while performing a temperature control based on the estimated temperatures. The heat treatment apparatus 1 includes a processing vessel 11 accommodating plural wafers W, plural heaters 31 to 33 and plural temperature sensors S1 to S5, and stores the thermal model. The heat treatment apparatus 1 estimates temperatures of the wafers W based on outputs of the temperature sensors S1 to S5 by using the thermal model and controls the heaters 31 to 33 based on the estimated temperatures, applying a heat treatment to the wafers W. The thermal model for an individual apparatus is made by calibrating a standard thermal model designed for a standard apparatus. The standard model calibration is performed by heating an interior of the processing vessel 11, measuring the temperatures of the wafers W in the processing vessel 11, estimating the temperatures of the wafers W by using the thermal model, comparing the measured temperature and the estimated temperature, and calibrating the standard thermal model so that the measured temperature substantially coincide with the estimated temperature.
    • 本发明在通过使用热模型估计过程物体的温度并在基于估计的温度执行温度控制的同时进行热处理的热处理设备中提供精确的温度估计。 热处理装置1包括容纳多个晶片W的处理容器11,多个加热器31〜33以及多个温度传感器S1〜S5,并存储热模型。 热处理装置1通过使用热模型,基于温度传感器S 1〜S 5的输出来估计晶片W的温度,并基于估计的温度控制加热器31〜33,对晶片W进行热处理。 单个设备的热模型通过校准为标准设备设计的标准热模型来进行。 通过加热处理容器11的内部,测量处理容器11中的晶片W的温度,通过使用热模型估计晶片W的温度,比较测量的温度和估计的温度来执行标准模型校准 ,并校准标准热模型,使得测量的温度基本上与估计的温度一致。
    • 18. 发明授权
    • Assist grip
    • 辅助抓地力
    • US08661622B2
    • 2014-03-04
    • US13638265
    • 2011-05-10
    • Hajime TakaiChiharu TotaniKazuhiro KawamuraShoji Kawakami
    • Hajime TakaiChiharu TotaniKazuhiro KawamuraShoji Kawakami
    • A45C3/00B60N3/02E05B1/00
    • B60N3/026B60N3/023
    • An assist grip includes hinges, spring cases, and coil springs. The hinges are provided with a rotary axis that a shaft-shaped protrusion and a pin make. The shaft-shaped protrusion is formed integrally with the hinges. The pin is formed independently of the hinges. The spring cases are held in a depression with which the hinges are provided, respectively. The coil springs urge the hinges by way of the spring cases in a direction for accommodating the hinges into hinge-holding depressions with which the assist grip is provided. The setup enables the resulting assist grip to offer better assemblage workability for assembly workers or robots, to show a better appearance, and to exhibit higher strength in service.
    • 辅助把手包括铰链,弹簧箱和螺旋弹簧。 铰链设置有轴形突起和销钉制成的旋转轴线。 轴状突起与铰链一体地形成。 销独立于铰链形成。 弹簧箱分别保持在设置有铰链的凹部中。 螺旋弹簧通过弹簧箱沿着将铰链容纳到设置有辅助把手的铰链保持凹部的方向上推动铰链。 该设置使得所得到的辅助把手能够为组装工人或机器人提供更好的组合可操作性,以显示更好的外观,并且在服务中表现出更高的强度。
    • 20. 发明申请
    • Assist grip
    • 辅助抓地力
    • US20100175220A1
    • 2010-07-15
    • US12591323
    • 2009-11-17
    • Hideki KajioShouji KawakamiKazuhiro KawamuraYoshiyuki Sakuma
    • Hideki KajioShouji KawakamiKazuhiro KawamuraYoshiyuki Sakuma
    • B25G1/00
    • B60N3/023B60N3/026Y10T16/44Y10T16/513
    • An assist grip of the present invention includes a grip body provided at both side base portions thereof with hinge recess portions and a hinge portion rotatably and pivotally supported in each of the hinge recess portions of both sides, and is fixed via the hinge portion to a to-be-fixed portion in an automobile. In a pivot support portion of the hinge portion, an outer support piece and an inner support piece are provided at a distance from each other, and between the inner support piece and the outer support piece, a torsion coil spring stored in a spring case is inserted. One end portion of the torsion coil spring is locked to an inside of the spring case, and the other end portion of the torsion coil spring projects from the spring case and is locked to a part of the grip body.
    • 本发明的辅助手柄包括一个把手本体的两侧基部设置有铰链凹部,铰链部分可旋转地并且可枢转地支撑在两侧的每个铰链凹部中,并通过铰链部分被固定到 汽车中的固定部分。 在铰链部的枢轴支撑部分中,外支撑件和内支撑件设置成彼此间隔一定距离,并且在内支撑件和外支撑件之间,存储在弹簧箱中的扭转螺旋弹簧是 插入。 扭力螺旋弹簧的一个端部被锁定在弹簧壳体的内部,而扭转螺旋弹簧的另一个端部从弹簧壳体突出并被锁定到手柄本体的一部分。