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11. 发明授权

US11343317B2 Data transmission method and device 有权
公开(公告)号：US11343317B2
公开(公告)日：2022-05-24
申请号：US16615683
申请日：2017-05-26
申请人： Siemens Aktiengesellschaft , He Yu , Yong Yuan , Hai Tao Zhang
发明人： He Yu , Yong Yuan , Hai Tao Zhang
IPC分类号： H04L67/12 , H04L69/18
摘要： Embodiments provide a data transmission method and apparatus. The method includes: after obtaining information of a target input port of a data receiving device and information of a target protocol used by a target Internet of Things device connected to the target input port, the data receiving device determines the target input port and the target protocol, and decapsulates, according to the target protocol, a first data packet transmitted by the target Internet of Things device via means of the target input port to obtain data. The data receiving device can adaptively determine a target protocol according to the information of the target protocol used by the target Internet of Things device, without configuring the target protocol for the target Internet of Things device in advance.

12. 发明授权

US10126291B2 Apparatus for disease detection 有权
公开(公告)号：US10126291B2
公开(公告)日：2018-11-13
申请号：US13856935
申请日：2013-04-04
申请人： Chris C Yu , Xuedong Du , He Yu
发明人： Chris C Yu , Xuedong Du , He Yu
IPC分类号： B01L3/00 , G01N33/50
摘要： The present invention provides, among others, apparatus for detecting a disease, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electric, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, physical, or mechanical property of the biologic material.

13. 发明申请

US20140030799A1 APPARATUS FOR DETECTING TUMOR CELLS 有权
标题翻译：检测肿瘤细胞的装置
公开(公告)号：US20140030799A1
公开(公告)日：2014-01-30
申请号：US14110759
申请日：2012-05-04
申请人： Chris C. Yu , Xuedong Du , He Yu
发明人： Chris C. Yu , Xuedong Du , He Yu
IPC分类号： G01N33/50 , C12Q1/68
CPC分类号： G01N33/574 , A61B5/07 , A61B5/14503 , A61B5/1451 , A61B5/14517 , A61B5/14528 , A61B5/14546 , A61B10/0041 , A61B2562/028 , A61B2562/12 , B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L3/502761 , B01L2200/0647 , B01L2200/0652 , B01L2200/0663 , B01L2200/0668 , B01L2300/0627 , B01L2300/0636 , B01L2300/0645 , B01L2300/0681 , B01L2300/0858 , B01L2300/0887 , B01L2300/123 , B01L2300/163 , B01L2400/0487 , C12Q1/68 , G01N1/34 , G01N1/4077 , G01N15/1056 , G01N15/1484 , G01N33/487 , G01N33/5091 , G01N33/54366 , G01N2001/4088 , G01N2015/0065 , G01N2015/1006 , G01N2015/1062 , G01N2015/1486
摘要： Among others, the present invention provides apparatus for detecting circulating tumor cells, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electrical, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, electro-mechanical, electro-chemical, electro-optical, electro-thermal, electro-chemical-mechanical, bio-chemical, bio-mechanical, bio-optical, bio-thermal, bio-physical, bio-electro-mechanical, bio-electro-chemical, bio-electro-optical, bio-electro-thermal, bio-mechanical-optical, bio-mechanical thermal, bio-thermal-optical, bio-electro-chemical-optical, bio-electro-mechanical-optical, bio-electro-thermal-optical, bio-electro-chemical-mechanical, physical or mechanical property, or a combination thereof, of the biologic subject.
摘要翻译：其中，本发明提供了一种检测循环肿瘤细胞的装置，包括系统递送生物体和探测和检测装置，其中探测和检测装置包括第一微器件和支撑第一微器件的第一基片，第一微型装置接触待检测的生物材料，并且能够在微观层面上测量电，磁，电磁，热，光，声，生物，化学，机电，电化学，电光学，电热，电化学机械，生物化学，生物机械，生物光学，生物热，生物物理，生物电机械，生物电化学，生物电光学，电热，生物机械光学，生物机械热学，生物热光学，生物电化学光学，生物机电光学，生物电热光学，生物电化学机械，物理或机械 rty或其组合。

14. 发明授权

US10996642B2 Method and apparatus for determining data reading cycle 有权
公开(公告)号：US10996642B2
公开(公告)日：2021-05-04
申请号：US16479011
申请日：2017-08-29
申请人： Siemens Aktiengesellschaft , He Yu , Qi Wang , Yong Yuan , Ming Zhang , Teng Fei Wu
发明人： Qi Wang , Yong Yuan , He Yu , Ming Zhang , Teng Fei Wu
IPC分类号： G05B17/02 , G06F16/28
摘要： In the field of industrial automation, a method and device are for determining a data reading period for determining a data reading period of data in an industrial control system, and are capable of automatically configuring the data reading period to obtain a better configuration result. In embodiments of the present invention, an industrial control system in different states is simulated by using simulation software to obtain a simulation model and simulation data. Data features of the industrial control system in different states that is simulated can be extracted respectively, and a data reading period is determined according to the extracted data features. Automatic configuring of a data reading period is implemented.

15. 发明授权

US10105317B2 Method of drug delivery 有权
公开(公告)号：US10105317B2
公开(公告)日：2018-10-23
申请号：US12498698
申请日：2009-07-07
申请人： Chris C. Yu , He Yu
发明人： Chris C. Yu , He Yu
IPC分类号： A61K9/00
摘要： A drug delivery method for effective drug application is disclosed in this invention. In this method, a micro-carrier delivers an encapsulated, desired drug directly to targeted sites without significant interactions with other components in the biological system in the pathway. In one embodiment, a micro-carrier containing encapsulated drug is first delivered to the general area for treatment. It then scans the area and selectively attaches itself the cell site or organ location to be treated. Finally, the desired drug contained in the micro-carrier is released to the attached cell or organ. In another embodiment, a micro-device is first used to process the general area to be treated to enhance differentiation in properties (such as surface charge) between healthy cells and unhealthy cells (such as cancer cells). Drug encapsulated in the micro-carrier is next applied to preferentially attach onto the targeted sites (such as cancer cell sites) to be treated. Finally, drug is released from the micro-carrier onto the sites to be treated. Such micro-carrier preferably contains multiple functions comprised of at least two functions from the group of sensing, analyzing, logic processing, surface treatment, position detection, motion, injecting, delivering, cutting functions, removing functions, biodegradation and disintegration.

16. 发明授权

US09655552B2 Devices for detecting or filtering tumor cells 有权
公开(公告)号：US09655552B2
公开(公告)日：2017-05-23
申请号：US14072609
申请日：2013-11-05
申请人： Chris C. Yu , Xuedong Du , He Yu
发明人： Chris C. Yu , Xuedong Du , He Yu
IPC分类号： G01N33/00 , A61B5/145 , G01N15/10 , C12Q1/68 , G01N33/50 , G01N1/34 , A61B5/07 , B01L3/00 , A61B10/00 , G01N1/40 , G01N15/14 , G01N33/574 , G01N33/543 , G01N15/00
CPC分类号： G01N33/574 , A61B5/07 , A61B5/14503 , A61B5/1451 , A61B5/14517 , A61B5/14528 , A61B5/14546 , A61B10/0041 , A61B2562/028 , A61B2562/12 , B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L3/502761 , B01L2200/0647 , B01L2200/0652 , B01L2200/0663 , B01L2200/0668 , B01L2300/0627 , B01L2300/0636 , B01L2300/0645 , B01L2300/0681 , B01L2300/0858 , B01L2300/0887 , B01L2300/123 , B01L2300/163 , B01L2400/0487 , C12Q1/68 , G01N1/34 , G01N1/4077 , G01N15/1056 , G01N15/1484 , G01N33/487 , G01N33/5091 , G01N33/54366 , G01N2001/4088 , G01N2015/0065 , G01N2015/1006 , G01N2015/1062 , G01N2015/1486
摘要： Among others, the present invention provides devices each including a micro-filter, a shutter, a cell counter, a selector, a micro-surgical kit, a timer, and a data processing circuitry, wherein the micro-filter is capable of detecting or filtering circulating tumor cells.

17. 发明申请

US20140342441A1 APPARATUS FOR DISEASE DETECTION 审中-公开
标题翻译：疾病检测设备
公开(公告)号：US20140342441A1
公开(公告)日：2014-11-20
申请号：US13856935
申请日：2013-04-04
申请人： Chris C. Yu , Xuedong Du , He Yu
发明人： Chris C. Yu , Xuedong Du , He Yu
IPC分类号： G01N33/50 , C12Q1/68 , G01N33/68 , C12Q1/70
CPC分类号： G01N33/50 , B01L3/502707 , B01L3/502761 , B01L2200/0647 , B01L2200/0652 , B01L2200/0663 , B01L2200/0668 , B01L2400/0415 , B01L2400/043 , B01L2400/0487
摘要： The present invention provides, among others, apparatus for detecting a disease, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electric, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, physical, or mechanical property of the biologic material.
摘要翻译：本发明提供了一种用于检测疾病的装置，包括系统递送生物学对象和探测和检测装置，其中探测和检测装置包括支撑第一微器件的第一微器件和第一衬底，第一微型装置接触待检测的生物材料，并且能够在微观层面测量生物材料的电，磁，电磁，热，光学，声学，生物学，化学，物理或机械性质。

18. 发明申请

US20140073884A1 APPARATUS FOR DETECTING TUMOR CELLS 审中-公开
标题翻译：检测肿瘤细胞的装置
公开(公告)号：US20140073884A1
公开(公告)日：2014-03-13
申请号：US14115584
申请日：2012-05-04
申请人： Chris C. Yu , Xuedong Du , He Yu
发明人： Chris C. Yu , Xuedong Du , He Yu
IPC分类号： A61B5/145 , A61B5/07
CPC分类号： G01N33/574 , A61B5/07 , A61B5/14503 , A61B5/1451 , A61B5/14517 , A61B5/14528 , A61B5/14546 , A61B10/0041 , A61B2562/028 , A61B2562/12 , B01L3/502707 , B01L3/502715 , B01L3/50273 , B01L3/502761 , B01L2200/0647 , B01L2200/0652 , B01L2200/0663 , B01L2200/0668 , B01L2300/0627 , B01L2300/0636 , B01L2300/0645 , B01L2300/0681 , B01L2300/0858 , B01L2300/0887 , B01L2300/123 , B01L2300/163 , B01L2400/0487 , C12Q1/68 , G01N1/34 , G01N1/4077 , G01N15/1056 , G01N15/1484 , G01N33/487 , G01N33/5091 , G01N33/54366 , G01N2001/4088 , G01N2015/0065 , G01N2015/1006 , G01N2015/1062 , G01N2015/1486
摘要： Among others, the present invention provides apparatus for detecting circulating tumor cells, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electrical, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, electro-mechanical, electro-chemical, electro-optical, electro-thermal, electro-chemical-mechanical, bio-chemical, bio-mechanical, bio-optical, bio-thermal, bio-physical, bio-electro-mechanical, bio-electro chemical, bio-electro-optical, bio-electro-thermal, bio-mechanical-optical, bio-mechanical thermal, bio-thermal-optical, bio-electro-chemical-optical, bio-electro-mechanical-optical, bio electro-thermal-optical, bio-electro-chemical-mechanical, physical or mechanical property, or a combination thereof, of the biologic subject.
摘要翻译：其中，本发明提供了一种检测循环肿瘤细胞的装置，包括系统递送生物体和探测和检测装置，其中探测和检测装置包括第一微器件和支撑第一微器件的第一基片，第一微型装置接触待检测的生物材料，并且能够在微观层面上测量电，磁，电磁，热，光，声，生物，化学，机电，电化学，电光学，电热，电化学机械，生物化学，生物机械，生物光学，生物热，生物物理，生物电机械，生物电化学，生物电光学，生物电热力学，生物机械光学，生物机械热学，生物热光学，生物电化学光学，生物机电光学，生物电热光学，生物电化学机械，物理或机械的 rty或其组合。

19. 发明申请

US20130183660A1 Apparatus for Disease Detection 审中-公开
标题翻译：疾病检测装置
公开(公告)号：US20130183660A1
公开(公告)日：2013-07-18
申请号：US13807859
申请日：2011-06-30
申请人： Chris C Yu , He Yu , Xuedong Du
发明人： Chris C Yu , He Yu , Xuedong Du
IPC分类号： G01N33/50 , C12Q1/68 , C12Q1/70 , G01N27/416 , G01N33/68
CPC分类号： G01N33/50 , A61B5/00 , A61B2560/0406 , B01L3/5027 , B01L3/502707 , B01L2200/0652 , B01L2200/0663 , B01L2300/0645 , B01L2300/0654 , B01L2300/0681 , B01L2400/0415 , B01L2400/043 , C12Q1/68 , C12Q1/70 , G01N15/14 , G01N27/416 , G01N33/5005 , G01N33/68 , G01N35/1095 , Y10T436/143333
摘要： Among others, the present invention provides apparatus for detecting a disease, comprising a system delivery biological subject and a probing and detecting device, wherein the probing and detecting device includes a first micro-device and a first substrate supporting the first micro-device, the first micro-device contacts a biologic material to be detected and is capable of measuring at the microscopic level an electric, magnetic, electromagnetic, thermal, optical, acoustical, biological, chemical, physical, or mechanical property of the biologic material.
摘要翻译：其中，本发明提供了一种疾病检测装置，包括系统输送生物体和探测装置，其中探测和检测装置包括第一微器件和支撑第一微器件的第一基片，第一微器件接触待检测的生物材料，并且能够在微观层面测量生物材料的电，磁，电磁，热，光学，声学，生物学，化学，物理或机械性质。

20. 发明申请

US20130006103A1 Micro-Devices for Biomedical Applications and Method of Use of Same 审中-公开
标题翻译：用于生物医学应用的微型器件及其使用方法
公开(公告)号：US20130006103A1
公开(公告)日：2013-01-03
申请号：US13555858
申请日：2012-07-23
申请人： Chris C. Yu , He Yu
发明人： Chris C. Yu , He Yu
IPC分类号： A61B17/22 , A61B6/12 , A61B10/02 , A61M5/00 , A61B18/20 , A61B17/00 , A61B18/02 , A61B18/18 , A61B18/12 , A61B5/00 , A61M37/00
CPC分类号： A61B5/0215 , A61B5/00 , A61B5/07 , A61B5/417 , A61M37/0015 , A61M2037/0023
摘要： Among others, the present invention provides fabricated micro-devices for application in live biological systems, each comprising (a) an outer membrane, (b) a micro-mechanical, micro-chemical, micro-chemical-mechanical, micro-optical, micro-acoustical, micro-biological, micro-bio-chemical, micro-bio-chemical-mechanical, micro-electro-bio-chemical-mechanical, micro-electro-chemical-mechanical, micro-electro-bio-chemical-mechanical, micro-electro-mechanical, micro-electromagnetic-mechanical, micro-acoustic-mechanical, and micro-superconducting-mechanical properties, and (c) having a size as defined by the outer membrane ranging from 1 angstrom to 5 millimeters; and methods of using such fabricated micro-devices.
摘要翻译：其中，本发明提供了用于活体生物系统中的制造的微器件，每个包括（a）外膜，（b）微机械，微化学，微机械，微光学，微观 - 声学，微生物，微生物化学，微生物化学机械，微电生物化学机械，微电化学机械，微电生物化学机械，微观 - 电 - 机械，微电磁 - 机械，微声 - 机械和微超导 - 机械性能，和（c）具有由外膜定义的尺寸范围为1埃至5毫米的尺寸; 以及使用这种制造的微器件的方法。

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