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11. 发明授权

US06287456B1 Filtration system with filtrate volume indicator 有权
标题翻译：过滤系统含滤液体积指示剂
公开(公告)号：US06287456B1
公开(公告)日：2001-09-11
申请号：US09420284
申请日：1999-10-18
申请人： Jeffrey Eldon Fish , Elizabeth Deibler Gadsby
发明人： Jeffrey Eldon Fish , Elizabeth Deibler Gadsby
IPC分类号： B01D35143
CPC分类号： C02F1/003 , B01D29/05 , B01D29/603 , C02F2307/06 , Y10T137/8342
摘要： A fluid filtration system includes a mechanism for monitoring and indicating the volume of fluid that has passed through a filter 30. The mechanism includes a channel 42 in communication with a reservoir 22, a portion of which is visible exteriorly of the housing 12. The channel allows a minor portion of the fluid entering the housing via inlet 14 to flow into the reservoir, while allowing the remaining portion of fluid to flow through the outlet 16. The minor portion of fluid entering the reservoir may or may not have passed through the filter. In various embodiments, the system may also include an indicator such as a float 44, a plunger 54, or dye.
摘要翻译：流体过滤系统包括用于监测和指示已经通过过滤器30的流体的体积的机构。该机构包括与储存器22连通的通道42，储存器22的一部分在外壳12的外部可见。通道允许通过入口14进入壳体的少部分流体流入储存器，同时允许流体的剩余部分流过出口16.流入储存器的少量流体可以已经或可以不经过过滤器。在各种实施例中，系统还可以包括诸如浮子44，柱塞54或染料的指示器。

12. 发明授权

US6046378A Wettable article 失效
公开(公告)号：US6046378A
公开(公告)日：2000-04-04
申请号：US820403
申请日：1997-03-12
申请人： Roger Bradshaw Quincy, III , Elizabeth Deibler Gadsby
发明人： Roger Bradshaw Quincy, III , Elizabeth Deibler Gadsby
IPC分类号： A61F13/15 , A61F5/44 , A61F13/49 , A61F13/511 , A61L15/32 , A61L15/48 , A61L15/50 , C08J7/04 , D06M15/15 , D06M15/53 , A61F13/20
CPC分类号： D06M15/53 , A61L15/32 , A61L15/48 , A61L15/50 , D06M15/15 , D06M2101/20 , D06M2200/00
摘要： A wettable article consisting of an article with a hydrophobic surface having a coating which includes a surface free energy modifier and a surface-active agent. The hydrophobic surface may include a hydrophobic polymer. The surface free energy modifier has a surface free energy greater than that of the surface of the article, but less than the surface tension of an aqueous liquid to which the wettable coated article may be exposed. The surface free energy modifier desirably is present in an amount sufficient to substantially cover the surface of the article. The surface-active agent is present in an amount effective to lower the surface tension of the liquid to a value which is greater than the surface free energy of the surface of the article and equal to or less than the surface free energy of the surface free energy modifier. The article desirably is a film or a fibrous web, such as a nonwoven web. Methods of preparing the wettable article also are described.

13. 发明授权

US5830367A Method of using indicator means for liquid purification filter 失效
标题翻译：使用液体净化过滤器指示器的方法
公开(公告)号：US5830367A
公开(公告)日：1998-11-03
申请号：US764676
申请日：1996-12-11
申请人： Elizabeth Deibler Gadsby
发明人： Elizabeth Deibler Gadsby
IPC分类号： A61L2/28 , B01D35/143 , B01J47/14 , B01D37/00 , G01N21/00
CPC分类号： A61L2/28 , B01D35/143 , B01J47/14
摘要： A method of monitoring the removal by a filter medium of a target substance from a liquid passing through the filter medium. The method involves: providing an indicator providing a filter medium having a plurality of binding sites which have a first affinity for the target substance and a second affinity for the indicator introducing the indicator means into the liquid; passing the liquid through the filter medium; and determining the presence or absence of the indicator in the liquid which has passed through the filter medium. The first and second affinities are adapted to require binding of the indicator by the filter medium only so long as binding sites are available to the target substance. Thus, the indicator means is adapted to compete with the target substance. As a practical matter, the liquid typically will be water. The indicator may denote when the filter medium is not effective by altering the taste of the water passing through the filter medium. Alternatively, the indicator may denote when the filter medium is not effective by altering the color of the water passing through the filter medium. For example, the indicator may impart a color to the water passing through the filter medium.
摘要翻译：一种通过过滤介质从通过过滤介质的液体中去除目标物质的方法。该方法包括：提供指示器，其提供具有多个结合位点的过滤介质，所述多个结合位点对于目标物质具有第一亲和力，并且对于将指示器装置引入液体中的指示剂的第二亲和力; 使液体通过过滤介质; 并确定已经通过过滤介质的液体中存在或不存在指示剂。第一和第二亲和力适用于仅当目标物质可获得结合位点时才需要通过过滤介质结合指示剂。因此，指示装置适于与目标物质竞争。实际上，液体通常是水。指示器可以表示当过滤介质通过改变通过过滤介质的水的味道而不能有效时。或者，指示器可以表示当过滤介质何时通过改变通过过滤介质的水的颜色而无效。例如，指示剂可以赋予通过过滤介质的水的颜色。

14. 发明授权

US06497893B1 Silk protein treatment composition and treated substrate for transfer to skin 失效
标题翻译：丝蛋白处理组合物和处理底物转移至皮肤
公开(公告)号：US06497893B1
公开(公告)日：2002-12-24
申请号：US09343861
申请日：1999-06-30
申请人： Dennis Stein Everhart , Robert Cosmo Di Luccio , Ali Yahiaoui , Wade Bolton May , David John Tyrrell , Elizabeth Deibler Gadsby , Gunilla Elsa Gillberg-LaForce
发明人： Dennis Stein Everhart , Robert Cosmo Di Luccio , Ali Yahiaoui , Wade Bolton May , David John Tyrrell , Elizabeth Deibler Gadsby , Gunilla Elsa Gillberg-LaForce
IPC分类号： A61N2534
CPC分类号： A61Q19/00 , A61K8/0208 , A61K8/64 , A61L15/18 , A61L15/32 , A61L15/48 , Y10S514/865
摘要： The present invention relates to a topical delivery system effective in depositing a thin, tenacious and substantially continuous coating of a silk protein on skin by an aqueous emulsion mediated dissolution of protein from a substrate with subsequent transfer and deposition onto the skin. Coatings of silk protein on skin resist removal, thereby providing a protective barrier against chemically- and biochemically-induced skin damage. The treatment composition also provides a vehicle for administering an effective dose of an active agent to the skin surface.
摘要翻译：本发明涉及一种局部递送系统，其有效地通过水性乳剂介导蛋白质从底物的溶解而沉积薄皮层，牢固且基本上连续的丝蛋白涂层，随后转移和沉积到皮肤上。皮肤上的丝蛋白涂层可以抵抗去除，从而为化学和生物化学诱导的皮肤损伤提供保护性屏障。治疗组合物还提供了向皮肤表面施用有效剂量的活性剂的载体。

15. 发明授权

US5855788A Chemically charged-modified filter for removing particles from a liquid and method thereof 失效
标题翻译：用于从液体中除去颗粒的化学充电改性过滤器及其方法
公开(公告)号：US5855788A
公开(公告)日：1999-01-05
申请号：US594879
申请日：1996-02-07
申请人： Dennis Stein Everhart , Elizabeth Deibler Gadsby , Rosann Marie Kaylor , Kristi Lynn Kiick-Fischer
发明人： Dennis Stein Everhart , Elizabeth Deibler Gadsby , Rosann Marie Kaylor , Kristi Lynn Kiick-Fischer
IPC分类号： B01D39/16 , A61L2/02 , B01D39/08 , B01D39/14 , D04H1/42 , D06M15/15 , D06M15/61 , D06M23/00 , B01D61/00 , B01D39/02
CPC分类号： D06M23/005 , A61L2/022 , B01D39/1623 , D04H1/413 , D04H1/4374 , D06M15/15 , B01D2239/0208 , B01D2239/0216 , B01D2239/0421 , B01D2239/0428 , B01D2239/0478 , B01D2239/0609 , B01D2239/0618 , B01D2239/0622 , B01D2239/0636 , B01D2239/064 , B01D2239/065 , B01D2239/086
摘要： A chemically charged-modified filter for removing charged, micron to sub-micron sized particles from an aqueous liquid, the filter being composed of a filter sheet having a plurality of individual exposed surfaces, at least a portion of which having a surface energy of less than about 45 dynes per centimeter; amphiphilic macromolecules adsorbed onto at least some individual exposed surfaces having a surface energy of less than about 45 dynes per centimeter; and chemical charge modifiers incorporated onto at least a portion of the amphiphilic macromolecules; so that when said charge-modified substrate is in contact with the aqueous liquid containing the charged, micron to sub-micron sized particles, said particles are adsorbed onto the chemically charge-modified filter. Also disclosed is a method of removing charged, micron to sub-micron sized particles from an aqueous liquid in which an aqueous liquid containing charged, micron to sub-micron sized particles is passed through a chemically charge-modified filter.
摘要翻译：一种用于从水性液体中去除带电微米级至亚微米级颗粒的化学电荷改性过滤器，该过滤器由具有多个单独暴露表面的过滤片组成，其至少部分表面能较少比约45达因/厘米; 吸附在表面能小于约45达因/厘米的至少一些个别暴露表面的两亲大分子; 和掺入到至少一部分两亲性大分子上的化学电荷改性剂; 使得当所述电荷改性基底与含有带电微米到亚微米尺寸的颗粒的含水液体接触时，所述颗粒被吸附到化学电荷改性的过滤器上。还公开了一种从含水液体中除去带电微米级至亚微米级颗粒的方法，其中含有带电微米至亚微米级颗粒的水性液体通过化学电荷改性过滤器。

16. 发明授权

US5695829A Modified polymeric material having improved wettability 失效
标题翻译：具有改善的润湿性的改性聚合物材料
公开(公告)号：US5695829A
公开(公告)日：1997-12-09
申请号：US719595
申请日：1996-09-25
申请人： Roger Bradshaw Quincy, III , Ronald Sinclair Nohr , Elizabeth Deibler Gadsby
发明人： Roger Bradshaw Quincy, III , Ronald Sinclair Nohr , Elizabeth Deibler Gadsby
IPC分类号： B05D3/12 , D06M10/02 , D06M10/10 , D06M15/15 , D21H17/22 , D21H25/06 , B01J19/10
CPC分类号： B05D3/12 , D06M10/02 , D06M10/10 , D06M15/15 , D21H17/22 , D21H25/06
摘要： Proteins are applied to a polymeric article by contacting the polymeric article with a protein and exposing the contacted polymeric article to a frequency with a sufficient power dissipation for a sufficient period of time. A frequency range for applying proteins to a polymeric article is between about 5 kHz to about 40 kHz with a minimum power dissipated of about 1 watt. As a result, polymeric articles so treated exhibit improved water wettability, proteins may be applied to the polymeric articles very rapidly and more uniformly than by other methods, and polymeric articles having selected zones of wettability may be produced.
摘要翻译：通过使聚合物与蛋白质接触并将接触的聚合物物品暴露于具有足够功率耗散的频率足够的时间段，将蛋白质施加到聚合物制品上。将蛋白质应用于聚合物品的频率范围在约5kHz至约40kHz之间，最小功率消耗约1瓦特。结果，如此处理的聚合物制品表现出改善的水润湿性，可以比通过其它方法非常快速和更均匀地将蛋白质施加到聚合物制品，并且可以生产具有选定湿润性区域的聚合物制品。

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