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    • 11. 发明申请
    • ANALYTE MEASUREMENT METHOD AND SYSTEM WITH HEMATOCRIT COMPENSATION
    • 分析测量方法和系统与HEMATOCRIT补偿
    • WO2012035297A1
    • 2012-03-22
    • PCT/GB2011/001342
    • 2011-09-13
    • LIFESCAN SCOTLAND LIMITEDCRAGGS, AdamMALECHA, MichaelBLYTHE, Steve
    • CRAGGS, AdamMALECHA, MichaelBLYTHE, Steve
    • A61B5/1486G01N33/487
    • C12Q1/54A61B5/1486G01N27/3273
    • Described and illustrated herein are systems and exemplary methods of operating an analyte measurement system having a meter and a test strip. In one embodiment, the method may be achieved by applying a first test voltage between a reference electrode and a second working electrode and applying a second test voltage between the reference electrode and a first working electrode; measuring a first test current, a second test current, a third test current and a fourth test current at the second working electrode after a blood sample containing an analyte is applied to the test strip;; measuring a fifth test current at the first working electrode; estimating a hematocrit- corrected analyte concentration from the first, second, third, fourth and fifth test currents; and annunciating the hematocrit-corrected analyte concentration.
    • 本文描述和示出了操作具有仪表和测试条的分析物测量系统的系统和示例性方法。 在一个实施例中,可以通过在参考电极和第二工作电极之间施加第一测试电压并且在参考电极和第一工作电极之间施加第二测试电压来实现该方法; 将含有分析物的血液样本施加到测试条上之后,测量第二工作电极处的第一测试电流,第二测试电流,第三测试电流和第四测试电流; 在第一工作电极处测量第五测试电流; 从第一,第二,第三,第四和第五测试电流估计血细胞比容校正的分析物浓度; 并说明血细胞比容校正的分析物浓度。
    • 13. 发明申请
    • SHAPE MEMORY ALLOY EJECTION MECHANISM FOR EJECTING A TEST STRIP FROM A TEST METER
    • 用于从测试仪器中排出测试条的形状记忆合金排出机构
    • WO2011095775A1
    • 2011-08-11
    • PCT/GB2011/000143
    • 2011-02-03
    • LIFESCAN SCOTLAND LIMITEDDEANGELI, MarcoVALSECCHI, Luca
    • DEANGELI, MarcoVALSECCHI, Luca
    • G01N33/487
    • G01N33/48757
    • A test strip ejection mechanism, for use with a test strip receiving port and a test strip, includes a framework, an elongated shape memory alloy (SMA) strip (e.g., a SMA wire), a slider, and a heating module. The SMA strip has first and second ends that are attached to the framework and exhibits a solid state transition temperature. The slider is configured to travel along the framework. The heating module is configured to heat the SMA strip from a temperature below the solid state transition temperature to a temperature above the solid state transition temperature. Moreover, the SMA strip and slider are configured such that the slider travels along the framework under an applied force exerted on the slider by the SMA strip as the shape memory strip is heated from a temperature below the solid state transition temperature to a temperature above the solid state temperature by the heating module. In addition, the slider has a proximal end configured to engage a test strip received within a test strip receiving port and eject the test strip from the test strip receiving port as the slider travels along the framework. A test meter for use with a test strip includes a test strip receiving port and a test strip ejection mechanism.
    • 用于测试条接收端口和测试条的测试条弹出机构包括框架,细长形状记忆合金(SMA)条(例如SMA线),滑块和加热模块。 SMA带具有连接到框架并具有固态转变温度的第一和第二端。 滑块被配置为沿着框架行进。 加热模块被配置为将SMA条带从低于固态转变温度的温度加热到高于固态转变温度的温度。 此外,SMA条和滑块被构造成使得当形状记忆条被从低于固态转变温度的温度加热到高于固态转变温度的温度时,滑块在由SMA条带施加在滑块上的施加力下沿框架行进 固态温度由加热模块组成。 另外,滑块具有近端,其被配置为接合容纳在测试条接收端口内的测试条,并且当​​滑块沿着框架行进时将测试条从测试条接收端口排出。 用于测试条的测试仪包括测试条接收端口和测试条弹出机构。
    • 15. 发明申请
    • ANALYTE MEASUREMENT METER OR SYSTEM INCORPORATING AN IMPROVED MEASUREMENT CIRCUIT
    • 分析改进的测量电路的分析仪或系统
    • WO2006070200A1
    • 2006-07-06
    • PCT/GB2005/005106
    • 2005-12-29
    • LIFESCAN SCOTLAND LIMITEDTAYLOR, David, William
    • TAYLOR, David, William
    • G01N33/487G01N27/416
    • G01N27/3273
    • Many aspects of the invention will be apparent from the following paragraphs and detailed description some of which are as follows. In one example, the invention includes a circuit for measuring an analyte or indicator in a body fluid sample including a reference voltage circuit, at least one measurement line, a result line, a buffering circuit between the voltage reference circuit and the measurement line wherein the buffering circuit comprises at least one operational amplifier the output of which is connected to the result line. The circuit may be a glucose concentration measurement circuit delivering the glucose concentration in a body fluid such as for example blood, plasma, interstitial fluid, urine. The circuit may further form part of a meter or system for measuring glucose concentration in a body fluid.
    • 本发明的许多方面将从以下段落和详细描述中显而易见,其中一些如下。 在一个示例中,本发明包括用于测量体液样品中的分析物或指示器的电路,包括参考电压电路,至少一个测量线,结果线,电压参考电路和测量线之间的缓冲电路,其中 缓冲电路包括至少一个运算放大器,其输出端连接到结果行。 电路可以是葡萄糖浓度测量电路,其输送体液中的葡萄糖浓度,例如血液,血浆,间质液,尿。 电路还可以形成用于测量体液中的葡萄糖浓度的仪表或系统的一部分。
    • 16. 发明申请
    • ANALYTE MEASUREMENT MODULE AND A METER AND SYSTEM INCORPORATING SUCH A MODULE
    • 分析测量模块和与此类型模块配套的仪表和系统
    • WO2006070196A1
    • 2006-07-06
    • PCT/GB2005/005098
    • 2005-12-29
    • LIFESCAN SCOTLAND LIMITEDCOULSON, AlanTAYLOR, William, David
    • COULSON, AlanTAYLOR, William, David
    • G06F19/00G01N33/487A61B5/00
    • G01N33/48792A61B5/14532A61B5/1486G06F19/3456G16H40/63
    • A method of manufacturing a meter or system for measuring an analyte in a body fluid including the steps of defining a first hardware specification for an analyte measurement module. The step of defining a first software specification for an analyte measurement module. The step of manufacturing one or more analyte measurement modules according to said first hardware and software specifications. The step of defining a second hardware specification for said system module. And the step of defining a second software specification for said system module. The method further including the step of manufacturing one or more of said analyte measurement modules according to said first hardware and software specifications. The step of manufacturing one or more of said system modules according to said second hardware and software specifications. The step of testing said analyte measurement module to verify that said analyte measurement module meets said first hardware and software specifications. The step of testing said system module to verify that said system module meets said second hardware and software specifications. And the step of combining said analyte measurement module with said system module.
    • 一种制造用于测量体液中的分析物的仪表或系统的方法,包括为分析物测量模块定义第一硬件规格的步骤。 为分析物测量模块定义第一个软件规范的步骤。 根据所述第一硬件和软件规范制造一个或多个分析物测量模块的步骤。 为所述系统模块定义第二硬件规范的步骤。 以及为所述系统模块定义第二软件规范的步骤。 该方法还包括根据所述第一硬件和软件规范来制造一个或多个所述分析物测量模块的步骤。 根据所述第二硬件和软件规范制造一个或多个所述系统模块的步骤。 测试所述分析物测量模块以验证所述分析物测量模块满足所述第一硬件和软件规范的步骤。 测试所述系统模块以验证所述系统模块满足所述第二硬件和软件规范的步骤。 以及将所述分析物测量模块与所述系统模块组合的步骤。
    • 19. 发明申请
    • METHOD OF REDUCING THE EFFECT OF DIRECT AND MEDIATED INTERFERENCE CURRENT IN AN ELECTROCHEMICAL TEST STRIP
    • 降低直接和介质干扰电流在电化学测试条中的影响的方法
    • WO2005045417A1
    • 2005-05-19
    • PCT/GB2004/004599
    • 2004-10-29
    • LIFESCAN SCOTLAND LIMITEDDAVIES, Oliver, William, HardwickeMARSHALL, RobertBASKEYFIELD, Damian, Edward, HaydonWHYTE, LynseyLEIPER, Elaine
    • DAVIES, Oliver, William, HardwickeMARSHALL, RobertBASKEYFIELD, Damian, Edward, HaydonWHYTE, LynseyLEIPER, Elaine
    • G01N27/327
    • C12Q1/001A61B5/14532A61B5/1486A61B5/150022A61B5/150282A61B5/150358A61B5/150435A61B5/150503C12Q1/006G01N27/3274
    • The present invention is directed to a method of reducing interference in an electrochemical sensor (800) wherein the method includes the step of measuring a first current at a first working electrode (808), the first working electrode (808) being covered by an active reagent layer (820), the step of measuring a second current at a second working electrode (806), the second working electrode (806) being covered by an inactive reagent layer (818) and the step of calculating a corrected current value representative of a glucose concentration using a ratio of an active area of the first working electrode (808) to an inactive area of the second working electrode (806). The present invention is further directed to a method of reducing interferences in an electrochemical sensor (1000) wherein the method includes the step of measuring a first current at a first working electrode (100), the first working electrode (100) being covered by an active reagent layer (820), the step of measuring a second current at a second working electrode (102), wherein the active reagent layer (820) is disposed on an active region (102a) of the second working electrode (102) and an inactive region (102i) of the second working electrode (102) is covered by an inactive reagent layer (818) and the step of calculating a corrected current value representative of a glucose concentration using a ratio of an active region on the first and second working electrodes and an inactive region on the second working electrode.
    • 本发明涉及减少电化学传感器(800)中的干扰的方法,其中该方法包括测量第一工作电极(808)处的第一电流的步骤,第一工作电极(808)由有源 试剂层(820),在第二工作电极(806)测量第二电流的步骤,第二工作电极(806)被非活性试剂层(818)覆盖,并且计算代表 使用第一工作电极(808)的有效面积与第二工作电极(806)的无效区域的比率的葡萄糖浓度。 本发明还涉及减少电化学传感器(1000)中的干扰的方法,其中该方法包括测量第一工作电极(100)处的第一电流的步骤,第一工作电极(100)由 活性试剂层(820),在第二工作电极(102)测量第二电流的步骤,其中活性试剂层(820)设置在第二工作电极(102)的有源区(102a)上, 第二工作电极(102)的非活性区域(102i)被非活性试剂层(818)覆盖,并且使用第一和第二工作区域上的有效区域的比率来计算代表葡萄糖浓度的校正电流值的步骤 电极和第二工作电极上的非活性区域。