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131. 发明申请

US20120130361A1 ENDOMETRIAL ABLATION DEVICES AND SYSTEMS 审中-公开
标题翻译：子宫内膜剥离装置和系统
公开(公告)号：US20120130361A1
公开(公告)日：2012-05-24
申请号：US13236471
申请日：2011-09-19
申请人： Akos Toth , Dominique J. Filloux , Csaba Truckai
发明人： Akos Toth , Dominique J. Filloux , Csaba Truckai
IPC分类号： A61B18/18
CPC分类号： A61B18/042 , A61B18/1492 , A61B2018/00214 , A61B2018/00559 , A61B2018/00577 , A61B2018/00642 , A61B2018/00797 , A61B2018/00821 , A61B2018/00898 , A61B2018/122 , A61B2018/147 , A61B2090/3983
摘要： Systems and methods for endometrial ablation. The systems include a handle and elongated introducer sleeve extending to an expandable working end having a fluid-tight interior chamber. A thin dielectric wall surrounds at least a portion of the interior chamber and has an external surface for contacting endometrial tissue. The thin dielectric wall surrounds a collapsible-expandable frame and receives an electrically non-conductive gas. First and second polarity electrodes are exposed to the interior and exterior of the chamber, respectively. A radiofrequency power source operatively connects to the electrode arrangement to apply a radiofrequency voltage across the first and second electrodes, wherein the voltage is sufficient to initiate ionization of the neutral gas into a conductive plasma within the interior chamber, and to capacitively couple the current in the plasma across the thin dielectric wall to ablate endometrial tissue engaged by the external surface of the dielectric structure.
摘要翻译：子宫内膜消融的系统和方法。这些系统包括延伸到具有流体密封内部室的可扩展工作端的手柄和细长导引套筒。薄介电壁围绕内室的至少一部分并且具有用于接触子宫内膜组织的外表面。薄介电壁围绕可折叠的可膨胀框架并且接收非导电气体。第一和第二极性电极分别暴露于腔室的内部和外部。射频电源可操作地连接到电极装置以跨越第一和第二电极施加射频电压，其中电压足以启动中性气体离子化到内部室内的导电等离子体中，并将电流耦合到穿过薄介电壁的等离子体，以消融由电介质结构的外表面接合的子宫内膜组织。

132. 发明申请

US20110004208A1 ELECTROSURGICAL INSTRUMENT WITH REPLACEABLE CARTRIDGE 审中-公开
标题翻译：具有可更换墨盒的电磁仪
公开(公告)号：US20110004208A1
公开(公告)日：2011-01-06
申请号：US12605742
申请日：2009-10-26
申请人： Csaba Truckai , John Shadduck , James Baker
发明人： Csaba Truckai , John Shadduck , James Baker
IPC分类号： A61B18/14
CPC分类号： A61B18/1442 , A61B17/32 , A61B2017/2945 , A61B2018/00619 , A61B2018/00755 , A61B2018/00791 , A61B2018/00875 , A61B2018/1432 , A61B2018/1495
摘要： Various embodiments provide an electrosurgical instrument with a disposable electrosurgical cartridge. In one embodiment, the cartridge has first and second energy-delivery surfaces that carry first and second opposing polarity conductors coupled to a voltage source, together with first and second temperature-responsive variable impedance bodies exposed partly in the respective-delivery surfaces. The cartridge further carries a slidable blade member. The temperature-responsive variable impedance bodies are coupled to the voltage source by series and parallel circuitry. In use, the variable impedance bodies are adapted to modulate current flow and ohmic heating in engaged tissue by providing controlled current paths in the tissue and through the variable impedance bodies as the temperature-responsive bodies sense the temperature of adjacent engaged tissue. The engagement surfaces are capable of highly localized modulation of Rf energy application to engaged tissue to provide high and low temperatures, voltage and current in the tissue to create high strength welds.
摘要翻译：各种实施例提供具有一次性电外科手术盒的电外科器械。在一个实施例中，盒具有第一和第二能量传递表面，其承载耦合到电压源的第一和第二相对极性导体以及部分地暴露在相应输送表面中的第一和第二温度响应可变阻抗体。该盒还带有可滑动的刀片部件。温度响应可变阻抗体通过串联和并联电路耦合到电压源。在使用中，可变阻抗体适于通过在温度响应体感测相邻接合组织的温度时通过在组织中和通过可变阻抗体中提供受控的电流路径来调制接合组织中的电流和欧姆加热。接合表面能够对接合组织进行Rf能量的高度局部调节，以在组织中提供高和低温度，电压和电流以产生高强度焊缝。

133. 发明申请

US20090292290A1 BONE TREATMENT SYSTEMS AND METHODS 有权
标题翻译：骨治疗系统和方法
公开(公告)号：US20090292290A1
公开(公告)日：2009-11-26
申请号：US12427531
申请日：2009-04-21
申请人： Csaba Truckai , Andrew Kohm , John Shadduck
发明人： Csaba Truckai , Andrew Kohm , John Shadduck
IPC分类号： A61B17/58
CPC分类号： A61B17/8805 , A61B17/7095 , A61B17/8822 , A61B17/8827
摘要： Systems, bone cements and methods for treating vertebral compression fractures can utilize a bone cement comprising of a mixable liquid monomer component and a non-liquid component including polymer particles, wherein the non-liquid component is configured for controlled exposure to the liquid monomer over a setting interval of the bone cement. In a method of use, liquid and non-liquid components are mixed, and the bone cement is injected into bone wherein a lengthened setting interval is provided in which the mixture is configured for a flowability that prevents unwanted extravasation.
摘要翻译：用于治疗脊椎压缩性骨折的系统，骨水泥和方法可以利用包含可混合液体单体组分和包括聚合物颗粒在内的非液体组分的骨粘固剂，其中非液体组分构造成用于通过液体单体控制暴露于液体单体骨水泥的设定间隔。在使用方法中，将液体和非液体组分混合，并将骨粘固剂注入到骨中，其中提供了延长的凝固间隔，其中混合物配置为防止不想要的外渗的流动性。

134. 发明申请

US20090270849A1 Electrosurgical Device and Method 审中-公开
标题翻译：电外科手术装置及方法
公开(公告)号：US20090270849A1
公开(公告)日：2009-10-29
申请号：US12405025
申请日：2009-03-16
申请人： Csaba Truckai , Akos Toth
发明人： Csaba Truckai , Akos Toth
IPC分类号： A61B18/18
CPC分类号： A61B18/042
摘要： The present invention relates to the field of electrosurgery, and more particularly to a system that produces an ionized gas flows that are configured to function as an electrode arrangement. A working end of an elongated member can use spaced apart conductive gas flows to coagulate or ablate tissue interstitially, intraluminally or topically.
摘要翻译：本发明涉及电外科领域，更具体地说，涉及一种产生电离气流的系统，其配置为用作电极装置。细长构件的工作端可以使用间隔开的导电气流来间歇地，内向地或局部地凝结或消融组织。

135. 发明授权

US07512445B2 Moisture transport system for contact electrocoagulation 有权
标题翻译：用于接触电凝的水分输送系统
公开(公告)号：US07512445B2
公开(公告)日：2009-03-31
申请号：US11196025
申请日：2005-08-03
申请人： Csaba Truckai , Russel Mahlon Sampson , Stephanie Squarcia , Alfonso Lawrence Ramirez , Estela Hilario
发明人： Csaba Truckai , Russel Mahlon Sampson , Stephanie Squarcia , Alfonso Lawrence Ramirez , Estela Hilario
IPC分类号： A61F2/00 , A61B18/18
CPC分类号： A61B18/1482 , A61B17/42 , A61B18/14 , A61B18/1485 , A61B18/18 , A61B90/04 , A61B2017/22051 , A61B2017/4216 , A61B2018/00291 , A61B2018/00559 , A61B2018/00577 , A61B2018/00708 , A61B2018/126 , A61B2090/0409 , A61B2090/065 , A61M16/0427 , A61M16/0463 , A61M16/0481
摘要： An apparatus and method for use in performing ablation or coagulation of organs and other tissue includes a metallized fabric electrode array which is substantially absorbent and/or permeable to moisture and gases such as steam and conformable to the body cavity. The array includes conductive regions separated by insulated regions arranged to produce ablation to a predetermined depth. Following placement of the ablation device into contact with the tissue to be ablated, in RF generator is used to deliver RF energy to the conductive regions and to thereby induce current flow from the electrodes to tissue to be ablated. As the current heats the tissue, moisture (such as steam or liquid) leaves the tissue causing the tissue to dehydrate. Suction may be applied to facilitate moisture removal. The moisture permeability and/or absorbency of the electrode carrying member allows the moisture to leave the ablation site so as to prevent the moisture from providing a path of conductivity for the current.
摘要翻译：用于进行器官和其他组织的消融或凝结的装置和方法包括金属化织物电极阵列，其基本上吸收和/或可渗透水分和气体，例如蒸汽并且适应体腔。该阵列包括被设置为产生消融至预定深度的绝缘区域分开的导电区域。在将消融装置放置成与要消融的组织接触之后，在RF发生器中用于将RF能量传递到导电区域，并且由此诱导电流从电极流向要消融的组织。当电流加热组织时，水分（如蒸汽或液体）离开组织，导致组织脱水。可以采用抽吸以促进除湿。电极承载构件的透湿性和/或吸收性允许水分离开消融部位，以防止水分为电流提供导电路径。

136. 发明申请

US20080086196A1 POLYMER MATRIX DEVICES FOR TREATMENT OF VASCULAR MALFORMATIONS 审中-公开
标题翻译：用于治疗血管畸形的聚合物基质装置
公开(公告)号：US20080086196A1
公开(公告)日：2008-04-10
申请号：US11953809
申请日：2007-12-10
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61F2/06
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12118 , A61B17/12145 , A61B17/12172 , A61B17/12181 , A61B2017/12068 , A61F2/07 , A61F2/848 , A61F2220/0016
摘要： A system for treating a wide-neck aneurysm comprising a mesh-like sleeve fabricated from a class of polymer filaments that carry conductive particles therein to provide the filaments with a specified resistivity. The releasable mesh-like sleeve is introduced to the site of a targeted vascular malformation by the working end of a catheter that carries an electrode arrangement at its distal terminus. The system further provides an electrical source and controller (i) that modulates power delivery to the polymer matrix which can then fuse the sleeve to the wall of a blood vessel to span across the vascular malformation.
摘要翻译：一种用于治疗宽颈动脉瘤的系统，包括由一类聚合物长丝制成的网状套筒，所述聚合物细丝在其中携带导电颗粒以提供具有指定电阻率的细丝。可释放的网状套筒通过导管的工作端引导到目标血管畸形部位，该导管在其远端具有电极装置。该系统还提供一种电源和控制器（i），其调节向聚合物基质的功率传递，然后可将该套管熔合到血管的壁以横跨血管畸形。

137. 发明申请

US20060122625A1 Bone treatment systems and methods 有权
标题翻译：骨治疗系统和方法
公开(公告)号：US20060122625A1
公开(公告)日：2006-06-08
申请号：US11209035
申请日：2005-08-22
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61F2/34
CPC分类号： A61B17/8805 , A61B17/70 , A61B17/8822 , A61B17/8827 , A61B17/8836 , A61B2017/00022 , A61B2017/00026 , A61B2017/00084 , A61B2017/564 , A61F2/44
摘要： The present invention relates in certain embodiments to medical devices for treating vertebral compression fractures. More particularly, embodiments of the invention relate to instruments and methods for controllably restoring vertebral body height by controlling the flow of bone cement into the interior of a vertebra and the application of forces causes by the cement flow. An exemplary system utilizes Rf energy in combination a conductive bone cement for selectively polymerizing the inflow plume to increase the viscosity of the cement. In one aspect of the invention, the system utilizes a controller to control bone cement flow parameters to either allow or disallow cement interdigitation into cancellous bone. A method of the invention includes pulsing the flows of bone cement wherein high acceleration of the flow pulses can apply expansion forces across the surface of the cement plume to reduce a vertebral fracture.
摘要翻译：本发明在某些实施例中涉及用于治疗脊椎压缩性骨折的医疗装置。更具体地，本发明的实施例涉及通过控制骨水泥进入椎骨内部并且由水泥流引起的力的施加来可控地恢复椎体高度的仪器和方法。示例性系统利用结合导电骨水泥的Rf能量来选择性聚合流入羽流以增加水泥的粘度。在本发明的一个方面，该系统利用控制器来控制骨水泥流动参数以允许或不允许水泥交叉指向松质骨。本发明的方法包括脉动骨粘固剂的流动，其中流动脉冲的高加速度可以施加穿过水泥羽流表面的膨胀力，以减少椎骨骨折。

138. 发明申请

US20060106459A1 Bone treatment systems and methods 审中-公开
标题翻译：骨治疗系统和方法
公开(公告)号：US20060106459A1
公开(公告)日：2006-05-18
申请号：US11215730
申请日：2005-08-30
申请人： Csaba Truckai , John Shadduck
发明人： Csaba Truckai , John Shadduck
IPC分类号： A61F2/44
CPC分类号： A61B17/8836 , A61B17/7095 , A61B17/7098
摘要： A system for treating an abnormal vertebral body such as a compression fracture. In an exemplary embodiment, the system includes a biocompatible flow-through implant structure configured with a three-dimensional interior web that defines flow openings therein for cooperating with a two-part hardenable bone cement. The flow-through structure is capable of compacted and extended shapes and in one embodiment provides a gradient in flow openings for controlling flow parameters of a bone cement injected under high pressure into the interior thereof. The flow-through implant structure is configured for transducing cement injection forces into a selected direction for moving apart cortical endplates of a vertebra to reduce a fracture. In one embodiment, the flow-through implant structure is coupled to an Rf source for applying Rf energy to a two-part bone cement to accelerate curing of the cement to thereby allow on-demand alterations of cement viscosity. The Rf system allows for control of bone cement polymerization globally or regionally to prevent cement extravasion and to direct forces applied to a vertebra to reduce a fracture.
摘要翻译：用于治疗异常椎体的系统，例如压缩性骨折。在一个示例性实施例中，该系统包括生物相容性流通植入结构，该植入结构被构造成具有限定其中的流动开口的三维内部腹板，用于与两部分可硬化骨粘固剂配合。流通结构能够压实和延伸形状，并且在一个实施例中提供流动开口中的梯度，用于控制在高压下注入其内部的骨粘固剂的流动参数。流通植入结构被配置为将水泥注射力转换到选定的方向以移动分开的椎骨的皮层终板以减少骨折。在一个实施例中，流过植入结构耦合到Rf源，以将Rf能量施加到两部分骨水泥以加速水泥的固化，从而允许水泥粘度的按需改变。 Rf系统允许全局或区域地控制骨水泥聚合，以防止水泥外渗，并引导施加到椎骨上的力以减少骨折。

139. 发明申请

US20060025758A1 Radio-frequency generator for powering an ablation device 有权
公开(公告)号：US20060025758A1
公开(公告)日：2006-02-02
申请号：US11211016
申请日：2005-08-24
申请人： Bruno Strul , Csaba Truckai , Russel Sampson , Mark Kane
发明人： Bruno Strul , Csaba Truckai , Russel Sampson , Mark Kane
IPC分类号： A61B18/18
CPC分类号： A61B18/1206 , A61B18/1485 , A61B18/1492 , A61B2018/00214 , A61B2018/00559 , A61B2018/00684 , A61B2018/00702 , A61B2018/00761 , A61B2018/00779 , A61B2018/00875 , A61B2018/00916 , A61B2018/124 , A61B2090/064 , A61B2218/007
摘要： An apparatus and method for use in performing ablation of organs and other tissues includes a radio frequency generator which provides a radio frequency signal to ablation electrodes. The power level of the radio frequency signal is determined based on the subject area of ablation. The radio frequency signal is coupled with the ablation electrodes through a transformation circuit. The transformation circuit includes a high impedance transformation circuit and a low impedance transformation circuit. The high or low impedance transformation circuit is selected based on the impedance of the ablation electrodes in contact with the subject tissue. Vacuum level, impedance level, resistance level, and time are measured during ablation. If these parameters exceed determinable limits the ablation procedure is terminated.

140. 发明申请

US20050267468A1 Moisture transport system for contact electrocoagulation 有权
标题翻译：用于接触电凝的水分输送系统
公开(公告)号：US20050267468A1
公开(公告)日：2005-12-01
申请号：US11196025
申请日：2005-08-03
申请人： Csaba Truckai , Russel Sampson , Stephanie Squarcia , Alfonso Ramirez , Estela Hilario
发明人： Csaba Truckai , Russel Sampson , Stephanie Squarcia , Alfonso Ramirez , Estela Hilario
IPC分类号： A61B17/22 , A61B17/42 , A61B18/14 , A61M1/00 , A61M16/04
CPC分类号： A61B18/1482 , A61B17/42 , A61B18/14 , A61B18/1485 , A61B18/18 , A61B90/04 , A61B2017/22051 , A61B2017/4216 , A61B2018/00291 , A61B2018/00559 , A61B2018/00577 , A61B2018/00708 , A61B2018/126 , A61B2090/0409 , A61B2090/065 , A61M16/0427 , A61M16/0463 , A61M16/0481
摘要： An apparatus and method for use in performing ablation or coagulation of organs and other tissue includes a metallized fabric electrode array which is substantially absorbent and/or permeable to moisture and gases such as steam and conformable to the body cavity. The array includes conductive regions separated by insulated regions arranged to produce ablation to a predetermined depth. Following placement of the ablation device into contact with the tissue to be ablated, in RF generator is used to deliver RF energy to the conductive regions and to thereby induce current flow from the electrodes to tissue to be ablated. As the current heats the tissue, moisture (such as steam or liquid) leaves the tissue causing the tissue to dehydrate. Suction may be applied to facilitate moisture removal. The moisture permeability and/or absorbency of the electrode carrying member allows the moisture to leave the ablation site so as to prevent the moisture from providing a path of conductivity for the current.
摘要翻译：用于进行器官和其他组织的消融或凝结的装置和方法包括金属化织物电极阵列，其基本上吸收和/或可渗透水分和气体，例如蒸汽并且适应体腔。该阵列包括被设置为产生消融至预定深度的绝缘区域分开的导电区域。在将消融装置放置成与要消融的组织接触之后，在RF发生器中用于将RF能量传递到导电区域，并且由此诱导电流从电极流向要消融的组织。当电流加热组织时，水分（如蒸汽或液体）离开组织，导致组织脱水。可以采用抽吸以促进除湿。电极承载构件的透湿性和/或吸收性允许水分离开消融部位，以防止水分为电流提供导电路径。

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