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131. 发明公开

EP2659962A4 TARGET MATERIAL CONVERSION METHOD, CRYSTAL MANUFACTURING METHOD, COMPOSITION MANUFACTURING METHOD, AND TARGET MATERIAL CONVERSION DEVICE 审中-公开
标题翻译： ZIELMATERIALUMWANDLUNGSVERFAHREN，KRISTALLHERSTELLUNGSVERFAHREN，VERFAHREN ZUR HERSTELLUNG EINER ZUSAMMENSETZUNG UND ZIELMATERIALUMWANDLUNGSVORRICHTUNG
公开(公告)号：EP2659962A4
公开(公告)日：2017-07-19
申请号：EP12736266
申请日：2012-01-18
申请人： UNIV OSAKA
发明人： MORI YUSUKE , INOUE TSUYOSHI , TAKANO KAZUFUMI , MATSUMURA HIROYOSHI , ADACHI HIROAKI , SUGIYAMA SHIGERU , MURAI RYOTA , KURATA MASATERU , YOSHIKAWA HIROSHI , HIRAO MIHOKO , NAKAYAMA SATOSHI , TAKAHASHI YOSHINORI , MURAKAMI SATOSHI
IPC分类号： B01J19/12 , B01J19/00 , B01J19/10 , C30B29/58
CPC分类号： B01J19/008 , B01D9/0081 , B01J19/10 , B01J19/121 , C30B5/00 , C30B29/58
摘要： The present invention provides a target substance transfer method, a crystal production method, a composition production method, and a target substance transfer device, which allow the concentration of a target substance to be increased easily and effectively. The target substance transfer method is a method for transferring a target substance 103 from a first phase 101 that is a liquid or solid phase containing the target substance 103 to a second phase 102 including: a phase approximation step of bringing the first phase 101 and the second phase 102 into close proximity; and a bubble collapse step of forming bubbles in the vicinity of a boundary between the first phase 101 and the second phase 102 and then causing the bubbles to collapse.
摘要翻译：本发明提供一种目标物质转移方法，结晶生产方法，组合物生产方法和目标物质转移装置，其允许目标物质的浓度容易且有效地增加。目标物质转移方法是用于将目标物质103从作为包含目标物质103的液相或固相的第一相101转移到第二相102的方法，该第二相包括：相位近似步骤，使第一相101和第二阶段102靠近; 以及在第一相101和第二相102之间的边界附近形成气泡然后使气泡崩溃的气泡破裂步骤。

132. 发明公开

EP3045523A4 THERMAL CONVECTION GENERATING CHIP, THERMAL CONVECTION GENERATING DEVICE, AND THERMAL CONVECTION GENERATING METHOD 有权
标题翻译： CHIP ZUR ERZEUGUNG VON THERMISCHER KONVEKTION，VORTHHTUNG ZUR ERZEUGUNG VON THERMISCHER KONVEKTION UND VERFAHREN ERZEUGUNG VON THERMISCHER KONVEKTION
公开(公告)号：EP3045523A4
公开(公告)日：2017-05-10
申请号：EP14844310
申请日：2014-03-07
申请人： UNIV OSAKA
发明人： SAITO MASATO , TAMIYA EIICHI
IPC分类号： C12Q1/68 , B01L3/00 , B01L7/00
CPC分类号： B01L7/525 , B01L3/50273 , B01L2200/06 , B01L2200/0684 , B01L2300/0636 , B01L2300/0803 , B01L2300/088 , B01L2300/1805 , B01L2400/0409 , B01L2400/0445 , B01L2400/0688 , C12P19/34 , C12Q1/686
摘要： A thermal convection generating device (1) that generates thermal convection of a liquid by heating or cooling the liquid and applying centrifugal force to the liquid, the thermal convection generating device including: a stage (20) to which a thermal convection generating chip (10) is attachable and detachable, the thermal convection generating chip including a disk-like substrate (11) and a thermal convection pathway (14) formed in a surface of the disk-like substrate that is perpendicular to an axis (AX) of the disk-like substrate, and being configured to rotate about the axis of the disk-like substrate to apply centrifugal force to a liquid in the thermal convection pathway; a heat controller (30) that heats or cools a portion of the thermal convection pathway; a motor (40) that drives the thermal convection generating chip to rotate about the axis; and a controller (50) that controls the heat controller and the motor.
摘要翻译： 1.一种热对流发生装置，其特征在于，具有：热对流发生装置，其通过对液体进行加热或冷却而产生液体的热对流，并对该液体施加离心力，其特征在于，具备：载置台，其设置有热对流发生芯片）可装卸地安装，所述热对流产生芯片具有圆盘状基板（11）和形成于所述圆盘状基板的与所述圆盘的轴线（AX）正交的面上的热对流路径（14）并且被配置为围绕所述盘状基底的轴线旋转以向所述热对流路径中的液体施加离心力; 热控制器（30），其加热或冷却热对流路径的一部分; 驱动所述热对流发生芯片绕所述轴线旋转的电动机（40）和控制器（50），其控制热量控制器和电机。

133. 发明公开

EP2985340A4 METHOD FOR CULTURING HEPATOBLAST-LIKE CELLS AND CULTURE PRODUCT THEREOF 审中-公开
标题翻译：方法进行繁殖HEPATOBLASTENÄHNLICHEN细胞和培养产物
公开(公告)号：EP2985340A4
公开(公告)日：2016-11-02
申请号：EP14782456
申请日：2014-04-08
申请人： NAT INST OF BIOMEDICAL INNOVATION HEALTH AND NUTRITION , UNIV OSAKA
发明人： MIZUGUCHI HIROYUKI , KAWABATA KENJI , TAKAYAMA KAZUO , SEKIGUCHI KIYOTOSHI
IPC分类号： C12N5/071 , A61L27/38 , C12N5/0789 , C12N5/10 , C12N15/09
CPC分类号： C12N5/067 , A61L27/3834 , C12N2533/52
摘要： Provided is a method of stably maintaining and culturing "hepatoblast-like cells" generated during a differentiation-inducing process from pluripotent stem cells to hepatocytes. The present invention also provides a culture product obtained by the culture method. The hepatoblast-like cells can be maintained and cultured stably by bringing a laminin into contact with the hepatoblast-like cells. The method of the present invention which uses a laminin makes it possible for the first time to culture, maintain, and proliferate the hepatoblast-like cells. Desired mature cells such as mature hepatocytes and bile duct epithelial cells can be generated in a short time period and can be acquired at a desired timing by maintaining the hepatoblast-like cells. Further, the resulting cultured hepatoblast-like cells were demonstrated to be capable of being induced to differentiate into mature hepatocytes, mature cholangiocytes, bile duct epithelial cells, and the like. Thus, a substantially pure culture product of the present invention can be utilized as a composition for transplantation for use in regeneration of hepatocytes and/or bile duct epithelial cells.

134. 发明公开

EP2957556A4 AROMATIC AMINO ACID DERIVATIVE AND POSITRON EMISSION TOPOGRAPHY (PET) PROBE UTILIZING SAME 有权
标题翻译：芳香氨基酸衍生物和发射正电子地形（PET）探测器SO
公开(公告)号：EP2957556A4
公开(公告)日：2016-09-14
申请号：EP14752083
申请日：2014-02-10
申请人： UNIV OSAKA , NARD INSTITUTE LTD
发明人： NAGAMORI SHUSHI , KANAI YOSHIKATSU , NAKAO HIDEKAZU , OGATA TOKUTARO
IPC分类号： C07C229/36
CPC分类号： A61K51/0402 , C07B2200/05 , C07C229/36 , C07C309/73 , C07C323/63 , C07C2101/02 , C07C2601/02 , C07C2601/04 , C07C2601/08 , C07C2601/14 , C07D295/096
摘要： A compound having a structure represented by the general formula (I): (wherein n is 0 or 1; R 1 represents a hydrogen atom (only if n = 0), a halogen atom, a C1-C6 alkyl group, a C1-C6 haloalkyl group, an optionally substituted amino group, an optionally substituted phenyl group, a C1-C6 alkylthio group, a C1-C6 alkoxy group, a C1-C6 haloalkoxy group or a C7-C12 aralkyloxy group; R 2 represents - (CH 2 ) p -[O(CH 2 ) q ] r -X (wherein X is a halogen atom, p is an integer of 1 to 6, q is an integer of 1 to 4, and r is an integer of 0 to 4); R 3 represents a hydrogen atom, a C1-C6 alkyl group, a C7-C16 aralkyl group or a C6-C14 aryl group; and R 4 represents a hydrogen atom or a C1-C6 alkyl group), or a pharmaceutically acceptable salt thereof excels FAMT in terms of the tendency to accumulate intensively in cancer, the affinity for LAT1 and the selectivity for cancer, and can be labeled using an automated synthesizer in clinical settings, and therefore is useful as a highly versatile PET imaging agent.

135. 发明公开

EP2860537A4 ELECTRICAL LEAKAGE DETECTION DEVICE 有权
标题翻译： ELEKTRISCHE LECKDETEKTIONSVORRICHTUNG
公开(公告)号：EP2860537A4
公开(公告)日：2016-06-08
申请号：EP13804351
申请日：2013-06-12
申请人： UNIV OSAKA CITY
发明人： TSUJIMOTO HIROAKI
IPC分类号： G01R31/02 , G01R15/20 , G01R33/06 , G01R33/09 , H01H83/02 , H02H3/33
CPC分类号： G01R31/024 , G01R15/205 , G01R15/207 , G01R31/025 , G01R33/063 , G01R33/09 , H01H83/02 , H02H3/33
摘要： There is a limit on the miniaturization of electric leakage detecting apparatuses including a ring-shaped magnetic material. Any thicker electric wires increase the size of the ring-shaped magnetic material. Additionally, it is difficult to place the ring-shaped magnetic material around the electric wires that have already been placed. In light of the foregoing, an electric leakage apparatus is provided. The electric leakage detecting apparatus is to be installed on a pair of power source lines connecting a power source and a load, and includes: a pair of holders configured to hold the power source lines, respectively; a fixing means configured to fix the holders at a predetermined interval; a pair of magnetic elements each placed on each of the holders while being parallel to the power source lines; a detecting means configured to detect a difference between magneto-resistance effects of the magnetic elements; and a driving means configured to feed a drive current to the magnetic elements.

136. 发明公开

EP2848352A4 WELDING METHOD, WELDING NOZZLE AND WELDING DEVICE 有权
标题翻译：焊接，焊接装置和焊接喷嘴
公开(公告)号：EP2848352A4
公开(公告)日：2016-05-25
申请号：EP13787442
申请日：2013-04-11
申请人： UNIV OSAKA
发明人： FUJII HIDETOSHI , MORISADA YOSHIAKI
IPC分类号： B23K9/29 , B23K9/167 , B23K9/173 , B23K9/32 , B23K10/02 , B23K26/14 , B23K26/20 , B23K103/02
CPC分类号： B23K9/325 , B23K9/167 , B23K9/173 , B23K10/02 , B23K26/1464 , B23K2203/02
摘要： A welding method in which an inert gas is supplied to the surface of an iron material from inside a cylindrical welding nozzle, and the surface of the iron material to which the inert gas is being supplied by the welding nozzle is heated, wherein oxygen in the atmosphere sucked by a drop in atmospheric pressure caused by the flow of the inert gas is introduced into a molten pool produced in the surface of the iron material. Consequently, it is possible to make the depth of penetration of the molten pool deeper by introducing oxygen into the molten pool and increase welding efficiency without preparing an additional oxygen supply source as in dual shield TIG welding.

137. 发明公开

EP2541795A4 WIRELESS COMMUNICATIONS SYSTEM, COMMUNICATIONS DEVICE, PROGRAM, AND INTEGRATED CIRCUIT 审中-公开
标题翻译：无线通信系统，通信设备，程序与集成电路
公开(公告)号：EP2541795A4
公开(公告)日：2016-05-18
申请号：EP11744807
申请日：2011-02-22
申请人： SHARP KK , UNIV OSAKA
发明人： GOTO JUNGO , HAMAGUCHI YASUHIRO , YOKOMAKURA KAZUNARI , NAKAMURA OSAMU , TAKAHASHI HIROKI , IBI SHINSUKE , SAMPEI SEIICHI , MIYAMOTO SHINICHI
IPC分类号： H04L1/00
CPC分类号： H04L1/005 , H03M13/296 , H04L1/0003 , H04L1/0009 , H04L1/0025 , H04L1/0069

138. 发明公开

EP2843048A4 NOVEL INTEGRIN alpha9beta1 LIGAND AND USES THEREOF 有权
标题翻译： NEUARTIGER INTEGRIN-ALPHA9BETA1-LIGAND UND VERWENDUNGEN DAVON
公开(公告)号：EP2843048A4
公开(公告)日：2016-05-11
申请号：EP13760999
申请日：2013-03-14
申请人： UNIV OSAKA
发明人： SEKIGUCHI KIYOTOSHI , SATO RYOKO , EZOE SACHIKO
IPC分类号： C12N15/09 , A61K38/00 , A61K45/00 , A61P19/00 , A61P29/00 , A61P31/04 , A61P35/00 , A61P35/02 , A61P37/02 , A61P43/00 , C07K7/06 , C07K16/28 , C12N5/071 , C12N5/10 , C12P21/02 , G01N33/15 , G01N33/50
CPC分类号： C07K7/06 , A61K38/00 , C07K7/08 , C07K14/4702 , C07K14/7055 , C07K16/18 , C07K16/28 , C07K16/2839 , C07K2317/34 , C12N5/0602 , G01N33/502 , G01N2500/02 , G01N2500/04

139. 发明公开

EP2894219A4 ARTIFICIAL SKIN TISSUE, ARTIFICIAL SKIN MODEL AND MANUFACTURING METHOD THEREFOR 失效转让
标题翻译： KÜNSTLICHESHAUTGEWEBE，KÜNSTLICHESHAUTMODELL UND HERSTELLUNGSVERFAHRENDAFÜR
公开(公告)号：EP2894219A4
公开(公告)日：2016-04-27
申请号：EP13834839
申请日：2013-09-04
申请人： UNIV OSAKA , BIOMEDICAL TECHNOLOGY HYBRID CO LTD
发明人： AKASHI MITSURU , MATSUSAKI MICHIYA , NAWANO MASAAKI , HASHIMOTO KOJI , SHIRAKATA YUJI
IPC分类号： A61L27/60 , A61L27/36 , A61L27/38 , C12N1/00 , C12N5/07 , C12N5/0784
CPC分类号： A61L27/60 , A61F2210/0076 , A61L27/3633 , A61L27/383 , A61L2430/34 , C12N5/0639 , C12N5/0698 , C12N2501/052 , C12N2502/09 , C12N2502/1121 , C12N2533/54
摘要： Provided is a novel method capable of manufacturing an artificial skin model including dendritic cells. A method for manufacturing an artificial skin model includes the following: forming a dermal tissue layer by culturing coated cells in which a cell surface is coated with a coating film containing an extracellular matrix component, so that the coated cells are layered; forming a basal layer including type IV collagen on the dermal tissue layer by bringing type IV collagen into contact with the dermal tissue layer; and forming an epidermal layer by arranging epidermal cells on the basal layer. At least one of the dermal tissue layer and the epidermal layer includes dendritic cells.
摘要翻译：提供了能够制造包括树突状细胞的人造皮肤模型的新方法。制造人造皮肤模型的方法包括：通过培养其中细胞表面涂覆有包含细胞外基质组分的涂膜的涂覆细胞来形成真皮组织层，使得涂覆的细胞层叠; 通过使IV型胶原与真皮组织层接触，在真皮组织层上形成包括IV型胶原蛋白的基底层; 并通过在基底层上布置表皮细胞形成表皮层。至少一个真皮组织层和表皮层包括树突状细胞。

140. 发明公开

EP2842976A4 GEL WITH SELF-RESTORABILITY AND SHAPE-MEMORY PROPERTY AND PROCESS FOR PRODUCING SAME 有权
标题翻译： WITH其制造SELBSTWIEDERHERSTELLBARKEITS-和形状记忆性以及方法通过凝胶
公开(公告)号：EP2842976A4
公开(公告)日：2016-04-20
申请号：EP13781751
申请日：2013-04-26
申请人： UNIV OSAKA
发明人： HARADA AKIRA , TAKASHIMA YOSHINORI , KAKUTA TAKAHIRO
IPC分类号： C08F220/10 , C08F2/10 , C08F220/54
CPC分类号： C08F2/10 , C08F220/06 , C08F220/18 , C08F220/20 , C08F220/56 , C08F220/58 , C08F2220/1825 , C08F220/54 , C08F212/08

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