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121. 发明授权

US4787020A Full-wave output type forward converter 失效
标题翻译：全波输出型正激转换器
公开(公告)号：US4787020A
公开(公告)日：1988-11-22
申请号：US156208
申请日：1988-02-16
申请人： Rihei Hiramatsu , Tokunari Inoue , Kazushi Watanabe
发明人： Rihei Hiramatsu , Tokunari Inoue , Kazushi Watanabe
IPC分类号： H02M3/28 , H01F27/28 , H02M3/335
CPC分类号： H02M3/33553
摘要： Disclosed is a full-wave output type forward converter wherein a main transformer having a primary winding connected in series with a switching element includes two secondary windings as winding halves divided by a center tap and electromagnetically coupled. A leakage self inductance can be reduced to obtain a high-frequency, high-power arrangement.
摘要翻译：公开了一种全波输出型正激变换器，其中具有与开关元件串联连接的初级绕组的主变压器包括两个次级绕组，作为被中心抽头除以电磁耦合的二次绕组。可以减小泄漏自感以获得高频，高功率的布置。

122. 发明申请

US20130197009A1 ANTAGONIST FOR MUTANT ANDROGEN RECEPTOR 审中-公开
标题翻译：拮抗剂对突变型受体的拮抗作用
公开(公告)号：US20130197009A1
公开(公告)日：2013-08-01
申请号：US13877358
申请日：2011-10-21
申请人： Yukitaka Ideyama , Sadao Kuromitsu , Takashi Furutani , Masayoshi Takeda , Satoshi Konagai , Tomohiro Yamada , Nobuaki Taniguchi , Yutaka Kondoh , Masaaki Hirano , Kazushi Watanabe , Takashi Sugane , Akio Kakefuda
发明人： Yukitaka Ideyama , Sadao Kuromitsu , Takashi Furutani , Masayoshi Takeda , Satoshi Konagai , Tomohiro Yamada , Nobuaki Taniguchi , Yutaka Kondoh , Masaaki Hirano , Kazushi Watanabe , Takashi Sugane , Akio Kakefuda
IPC分类号： C07D401/02 , C07D401/14 , C07D403/02
CPC分类号： C07D401/02 , A61K31/496 , A61K31/506 , C07D401/12 , C07D401/14 , C07D403/02 , C07D403/12
摘要： [Problem] An object of the present invention is to provide a novel anticancer drug which is useful for treating prostate cancer accompanying androgen receptor mutation[Means for Solution] The present inventors conducted thorough research on mutant androgen-related diseases for which the traditional anti-androgen drugs become ineffective. As a result, they found that the compound, which is an active ingredient of the pharmaceutical composition of the present invention, exhibits an inhibitory action against transcriptional activation in a human mutant androgen receptor (AR), and has an excellent antitumor action in a human prostate cancer-bearing mouse, thereby completing the present invention. Accordingly, the compound, which is an active ingredient of the pharmaceutical composition of the present invention, is useful for a series of androgen receptor-related diseases including prostate cancer.
摘要翻译：本发明的目的在于提供一种可用于治疗伴随雄激素受体突变的前列腺癌的新型抗癌药物。本发明人进行了关于雄激素相关疾病的全面研究，雄激素药物变得无效。结果发现，作为本发明的药物组合物的活性成分的化合物在人突变型雄激素受体（AR）中表现出对转录活化的抑制作用，并且在人体中具有优异的抗肿瘤作用前列腺癌的小鼠，从而完成本发明。因此，作为本发明的药物组合物的活性成分的化合物可用于一系列与前列腺癌有关的雄激素受体相关疾病。

123. 发明授权

US08013018B2 Aminoindane derivative or salt thereof 有权
标题翻译：氨基茚满衍生物或其盐
公开(公告)号：US08013018B2
公开(公告)日：2011-09-06
申请号：US12305254
申请日：2007-07-17
申请人： Satoshi Hayashibe , Shingo Yamasaki , Kazushi Watanabe , Nobuyuki Shiraishi , Daisuke Suzuki , Hiroaki Hoshii , Junya Ohmori , Takatoshi Kanayama
发明人： Satoshi Hayashibe , Shingo Yamasaki , Kazushi Watanabe , Nobuyuki Shiraishi , Daisuke Suzuki , Hiroaki Hoshii , Junya Ohmori , Takatoshi Kanayama
IPC分类号： A01N37/12 , A01N37/44 , A01N33/18 , A01N33/24 , A61K31/24 , A61K31/04
CPC分类号： C07C211/42 , C07C215/42 , C07C215/44 , C07C217/52 , C07C235/40 , C07C255/58 , C07C2602/08 , C07D209/40 , C07D221/16 , C07D295/12 , C07D307/82 , C07D333/78
摘要： Provided is a compound that is an NMDA receptor antagonist having a broader safety margin, and is useful as an agent for treating or preventing Alzheimer's disease, cerebrovascular dementia, Parkinson's disease, ischemic apoplexy, or pain.A novel compound or a salt thereof, which is characterized in that it has an amino group and R1 (lower alkyl, cycloalkyl, -lower alkylene-aryl, aryl which may be substituted, and the like) on carbon atoms of indane, cyclopenta[b]thiophene, cyclopenta[b]furan, cyclopenta[b]pyridine, or cyclopenta[c]pyridine ring, or 2,3 -dihydro-1-benzofuran, 2,3-dihydro-1-benzothiophene, indoline ring, or the like, and has R2 and R3 (the same or different, each lower alkyl or aryl) on carbon atoms beside them, and an NMDA receptor antagonist comprising the same as an active component.
摘要翻译：提供了具有更宽安全裕度的NMDA受体拮抗剂的化合物，可用作治疗或预防阿尔茨海默病，脑血管性痴呆，帕金森病，缺血性中风或疼痛的药剂。一种新型化合物或其盐，其特征在于其具有在茚满的环戊二烯基的碳原子上具有氨基和可以被取代的R 1（低级烷基，环烷基， - 低级亚烷基 - 芳基，芳基等） b]噻吩，环戊二烯并[b]呋喃，环戊二烯并[b]吡啶或环戊并[c]吡啶环，或2,3-二氢-1-苯并呋喃，2,3-二氢-1-苯并噻吩，二氢吲哚环，或并且在它们旁边的碳原子上具有R2和R3（相同或不同，各个低级烷基或芳基），以及包含与活性组分相同的NMDA受体拮抗剂。

124. 发明授权

US07620462B2 Robust digital controller and its designing device 失效
标题翻译：坚固的数字控制器及其设计装置
公开(公告)号：US07620462B2
公开(公告)日：2009-11-17
申请号：US11572778
申请日：2005-07-28
申请人： Kouji Higuchi , Kazushi Nakano , Tatsuyoshi Kajikawa , Eiji Takegami , Kazushi Watanabe , Satoshi Tomioka
发明人： Kouji Higuchi , Kazushi Nakano , Tatsuyoshi Kajikawa , Eiji Takegami , Kazushi Watanabe , Satoshi Tomioka
IPC分类号： G05B13/02 , G05B19/29 , G05B11/01
CPC分类号： G05B21/02 , G05B5/01 , H02M3/33515
摘要： A robust digital controller is equipped with a high degree of approximation and is able to incorporate a novel two-degree-of-freedom robust digital control system without substantially considering the magnitude of the control inputs and there is provided its designing device. A control compensating means is configured as an integral type control system in which a discrete transfer function Wry (z) between a target value r and a controlled variable y is approximated to a higher-approximate quadratic approximate model transfer function Wm (z) and an arithmetic processing can be performed within the digital controller based on the model transfer function Wm (z). Further, the designing device automatically calculates parameters constituting the control system. Consequently, a robust digital controller can be easily realized that is equipped with a high degree of approximation as compared with a conventional approximate digital control system for realizing a first-order model and is robust against output noises.
摘要翻译：强大的数字控制器具有高度的近似性，并且能够引入一种新颖的两度自由度鲁棒的数字控制系统，而基本上不考虑控制输入的大小，并提供其设计装置。控制补偿装置被配置为整体式控制系统，其中目标值r和受控变量y之间的离散传递函数Wry（z）近似于较高近似二次近似模型传递函数Wm（z），并且可以基于模型传递函数Wm（z）在数字控制器内执行算术处理。此外，设计装置自动计算构成控制系统的参数。因此，与用于实现一阶模型的常规近似数字控制系统相比，可以容易地实现具有高度近似的鲁棒数字控制器，并且对输出噪声是鲁棒的。

125. 发明申请

US20090186916A1 AMINOINDANE DERIVATIVE OR SALT THEREOF 有权
标题翻译：氨基衍生物或其盐
公开(公告)号：US20090186916A1
公开(公告)日：2009-07-23
申请号：US12305254
申请日：2007-07-17
申请人： Satoshi Hayashibe , Shingo Yamasaki , Kazushi Watanabe , Nobuyuki Shiraishi , Daisuke Suzuki , Hiroaki Hoshii , Junya Ohmori , Takatoshi Kanayama
发明人： Satoshi Hayashibe , Shingo Yamasaki , Kazushi Watanabe , Nobuyuki Shiraishi , Daisuke Suzuki , Hiroaki Hoshii , Junya Ohmori , Takatoshi Kanayama
IPC分类号： A61K31/135 , C07C211/38 , C07D333/78 , C07D307/93 , C07D221/04 , A61K31/381 , A61K31/343 , A61K31/44 , A61P25/00
CPC分类号： C07C211/42 , C07C215/42 , C07C215/44 , C07C217/52 , C07C235/40 , C07C255/58 , C07C2602/08 , C07D209/40 , C07D221/16 , C07D295/12 , C07D307/82 , C07D333/78
摘要： Provided is a compound that is an NMDA receptor antagonist having a broader safety margin, and is useful as an agent for treating or preventing Alzheimer's disease, cerebrovascular dementia, Parkinson's disease, ischemic apoplexy, or pain.A novel compound or a salt thereof, which is characterized in that it has an amino group and R1 (lower alkyl, cycloalkyl, -lower alkylene-aryl, aryl which may be substituted, and the like) on carbon atoms of indane, cyclopenta[b]thiophene, cyclopenta[b]furan, cyclopenta[b]pyridine, or cyclopenta[c]pyridine ring, or 2,3-dihydrdo-1-benzofuran, 2,3-dihydrdo-1-benzothiophene, indoline ring, or the like, and has R2 and R3 (the same or different, each lower alkyl or aryl) on carbon atoms beside them, and an NMDA receptor antagonist comprising the same as an active component.
摘要翻译：提供了具有更宽安全裕度的NMDA受体拮抗剂的化合物，可用作治疗或预防阿尔茨海默病，脑血管性痴呆，帕金森病，缺血性中风或疼痛的药剂。一种新型化合物或其盐，其特征在于其具有在茚满的环戊二烯基的碳原子上具有氨基和可以被取代的R 1（低级烷基，环烷基， - 低级亚烷基 - 芳基，芳基等） b]噻吩，环戊二烯并[b]呋喃，环戊二烯并[b]吡啶或环戊二烯并[c]吡啶环，或2,3-二氢-1-苯并呋喃，2,3-二氢-1-苯并噻吩，二氢吲哚环或并且在它们旁边的碳原子上具有R2和R3（相同或不同，各个低级烷基或芳基），以及包含与活性组分相同的NMDA受体拮抗剂。

126. 发明授权

US07231161B2 Coupling part, photosensitive drum, process cartridge and electrophotographic image forming apparatus 有权
标题翻译：耦合部分，感光鼓，处理盒和电子照相成像设备
公开(公告)号：US07231161B2
公开(公告)日：2007-06-12
申请号：US11417142
申请日：2006-05-04
申请人： Shinya Noda , Shinichi Sasaki , Akihiro Toma , Isao Ikemoto , Kazushi Watanabe , Akira Higeta
发明人： Shinya Noda , Shinichi Sasaki , Akihiro Toma , Isao Ikemoto , Kazushi Watanabe , Akira Higeta
IPC分类号： G03G15/00 , G03G21/18
CPC分类号： G03G15/757 , F16D1/101 , G03G21/1633 , G03G21/1647 , G03G21/1853 , G03G21/186 , G03G21/1864 , G03G21/1867 , G03G21/1871 , G03G2221/1654 , G03G2221/1657 , G03G2221/166 , G03G2221/183 , G03G2221/1861 , G03G2221/1884
摘要： A process cartridge detachably mountable to a main assembly of an electrophotographic image forming apparatus, wherein the main assembly includes a motor, a main assembly side gear for receiving driving force from the motor, a hole defined by twisted surfaces, the hole being substantially coaxial with the gear, and a main assembly side grounding contact provided in the hole, the process cartridge includes an electrophotographic photosensitive drum; process mechanisms actable on the photosensitive drum; and a projection engageable with the twisted surfaces, the projection being provided at a longitudinal end of the photosensitive drum, wherein when the main assembly side gear rotates with the hole and projection engaged with each other, rotational driving force is transmitted from the gear to the photosensitive drum through engagement between the hole and the projection; and a cartridge side grounding contact electrically connected with the electrophotographic photosensitive drum for electrically grounding the electrophotographic photosensitive drum when the process cartridge is mounted to the main assembly of the apparatus, the cartridge side grounding contact being provided on the projection so as to be electrically connectable with the main assembly side grounding contact
摘要翻译：一种可拆卸地安装到电子照相成像设备的主组件的处理盒，其中主组件包括电动机，用于接收来自电动机的驱动力的主组件侧齿轮，由扭曲表面限定的孔，该孔基本上与所述齿轮和设置在所述孔中的主组件侧接地触头，所述处理盒包括电子照相感光鼓; 可在感光鼓上作用的加工机构; 以及与所述扭转表面接合的突起，所述突起设置在所述感光鼓的纵向端部，其中当所述主组件侧齿轮随着所述孔和突起彼此接合而旋转时，旋转驱动力从所述齿轮传递到感光鼓通过孔和突起之间的接合; 以及与电子照相感光鼓电连接的盒侧接地触点，用于当处理盒安装到设备的主组件时将电子照相感光鼓电接地，盒侧接地触点设置在突起上以便可电连接与主组件侧接地。

127. 发明授权

US06999696B2 Coupling part, photosensitive drum, process cartridge and electrophotographic image forming apparatus 失效
公开(公告)号：US06999696B2
公开(公告)日：2006-02-14
申请号：US11084623
申请日：2005-03-21
申请人： Shinya Noda , Shinichi Sasaki , Akihiro Toma , Isao Ikemoto , Kazushi Watanabe , Akira Higeta
发明人： Shinya Noda , Shinichi Sasaki , Akihiro Toma , Isao Ikemoto , Kazushi Watanabe , Akira Higeta
IPC分类号： G03G15/00 , G03G21/18
CPC分类号： G03G15/757 , F16D1/101 , G03G21/1633 , G03G21/1647 , G03G21/1853 , G03G21/186 , G03G21/1864 , G03G21/1867 , G03G21/1871 , G03G2221/1654 , G03G2221/1657 , G03G2221/166 , G03G2221/183 , G03G2221/1861 , G03G2221/1884
摘要： A process cartridge detachably mountable to a main assembly of an electrophotographic image forming apparatus, wherein the main assembly includes a motor, a main assembly side gear for receiving driving force from the motor, a hole defined by twisted surfaces, the hole being substantially coaxial with the gear, and a main assembly side grounding contact provided in the hole, the process cartridge includes an electrophotographic photosensitive drum; process mechanisms actable on the photosensitive drum; and a projection engageable with the twisted surfaces, the projection being provided at a longitudinal end of the photosensitive drum, wherein when the main assembly side gear rotates with the hole and projection engaged with each other, rotational driving force is transmitted from the gear to the photosensitive drum through engagement between the hole and the projection; and a cartridge side grounding contact electrically connected with the electrophotographic photosensitive drum for electrically grounding the electrophotographic photosensitive drum when the process cartridge is mounted to the main assembly of the apparatus, the cartridge side grounding contact being provided on the projection so as to be electrically connectable with the main assembly side grounding contact.

128. 发明授权

US6029032A Process cartridge and electrophotographic image forming apparatus 失效
标题翻译：处理盒和电子照相成像设备
公开(公告)号：US6029032A
公开(公告)日：2000-02-22
申请号：US939118
申请日：1997-09-26
申请人： Kazushi Watanabe , Isao Ikemoto , Atsushi Numagami , Katsunori Yokoyama
发明人： Kazushi Watanabe , Isao Ikemoto , Atsushi Numagami , Katsunori Yokoyama
IPC分类号： F16D1/10 , G03G15/00 , G03G21/18 , G03G21/16
CPC分类号： G03G21/186 , F16D1/101 , G03G15/757 , G03G21/1633 , G03G21/1647 , G03G21/1864 , G03G2221/1654 , G03G2221/1657
摘要： A process cartridge detachably mountable to a main assembly of an electrophotographic image forming apparatus, wherein said main assembly includes a motor, a main assembly side gear for receiving driving force from said motor and a hole defined by twisted surfaces, said hole being substantially coaxial with said gear, said process cartridge includes an electrophotographic photosensitive drum; process means actable on said photosensitive drum; a projection engageable with said twisted surfaces, said projection being provided at a longitudinal end of said photosensitive drum, wherein said projection is non-twisted, and when said main assembly side gear rotates with said hole and projection engaged with each other, rotational driving force is transmitted from said gear to said photosensitive drum through engagement between said hole and said projection; and a resilient member for urging said process cartridge in a longitudinal direction of said photosensitive drum when said process cartridge is mounted to the main assembly.
摘要翻译：一种可拆卸地安装到电子照相成像设备的主组件的处理盒，其中所述主组件包括电动机，用于接收来自所述电动机的驱动力的主组件侧齿轮和由扭曲表面限定的孔，所述孔基本上与所述处理盒包括电子照相感光鼓; 处理装置可在所述感光鼓上作用; 可与所述扭转表面接合的突起，所述突起设置在所述感光鼓的纵向端部处，其中所述突起不扭曲，并且当所述主组件侧齿轮随着所述孔和突起彼此接合而旋转时，旋转驱动力通过所述孔和所述突起之间的接合从所述齿轮传递到所述感光鼓; 以及弹性构件，用于当所述处理盒安装到主组件时，沿着所述感光鼓的纵向推动所述处理盒。

129. 发明授权

US6022550A Crosslinkable polymer composition, molded article therefrom, process for the preparation thereof, crosslinked nonwoven cloth, and process for the preparation thereof 失效
标题翻译：可交联聚合物组合物，其模塑制品，其制备方法，交联无纺布及其制备方法
公开(公告)号：US6022550A
公开(公告)日：2000-02-08
申请号：US932840
申请日：1997-09-18
申请人： Kazushi Watanabe
发明人： Kazushi Watanabe
IPC分类号： C08F291/00 , C08K5/00 , A61K31/74 , A01N25/34
CPC分类号： C08F291/00 , C08K5/0008
摘要： Disclosed are a crosslinkable resin composition, and a molded article from the composition, a process for the preparation of the crosslinkable polymer composition, and crosslinked nonwoven cloth having a shape-memory effect and a process for the preparation thereof.The crosslinkable resin composition and the molded article of the present invention are excellent in chemical resistance.
摘要翻译：公开了一种交联性树脂组合物和来自组合物的成型体，制备可交联聚合物组合物的方法和具有形状记忆效应的交联无纺布及其制备方法。本发明的交联性树脂组合物和成型体的耐化学性优异。

130. 发明授权

US6016413A Assembling method of process cartridge, assembling method and process cartridge 失效
标题翻译：处理盒的组装方法，组装方法和处理盒
公开(公告)号：US6016413A
公开(公告)日：2000-01-18
申请号：US887457
申请日：1997-07-02
申请人： Katsunori Yokoyama , Kazushi Watanabe , Atsushi Numagami
发明人： Katsunori Yokoyama , Kazushi Watanabe , Atsushi Numagami
IPC分类号： G03G15/08 , G03G21/18 , G03G15/00
CPC分类号： G03G21/181 , G03G21/1825 , Y10T29/49904
摘要： An assembling method of a process cartridge detachably mountable to an image forming apparatus includes providing a drum frame, supporting an photosensitive drum and having first and second engaging portions above the electrophotographic photosensitive drum, one adjacent each longitudinal end of the electrophotographic photosensitive drum; and providing a developing device frame supporting a developer, and having first and second compression springs above the developer, one adjacent each longitudinal end of the developer, and first and second projected portions projected in a direction crossing with a longitudinal direction of the developer, one adjacent each longitudinal end of the developer. The first and second projected portions are engaged with the first and second engaging portions, respectively. A first penetrating member is penetrated through a first opening formed in the first projected portion and a third opening formed in the first engaging portion, and a second penetrating member is penetrated through a second opening formed in the second projected portion and a fourth opening formed in the second engaging portion, while the projected portions and the engaging portions are engaged with each other.
摘要翻译：可拆卸地安装到图像形成装置的处理盒的组装方法包括提供鼓框架，支撑感光鼓，并且在电子照相感光鼓上方具有与电子照相感光鼓的每个纵向端相邻的第一和第二接合部分; 并且提供支撑显影剂的显影装置框架，并且在显影剂上方具有第一和第二压缩弹簧，一个邻近显影剂纵向端部，以及沿与显影剂纵向交叉的方向突出的第一和第二突出部分，一个邻近显影剂的每个纵向端。第一和第二突起部分分别与第一和第二接合部分接合。第一穿透构件穿过形成在第一突出部分中的第一开口和形成在第一接合部分中的第三开口，并且第二穿透构件穿过形成在第二突出部分中的第二开口和形成在第二突出部分中的第四开口第二接合部分，同时突出部分和接合部分彼此接合。

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