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121. 发明申请

US20150291967A1 COUPLING HERBICIDE RESISTANCE WITH TARGETED INSERTION OF TRANSGENES IN PLANTS 审中-公开
标题翻译：与植物中特异性转移的插入物联合抗药性
公开(公告)号：US20150291967A1
公开(公告)日：2015-10-15
申请号：US14439413
申请日：2013-10-31
申请人： Luc MATHIS , Daniel VOYTAS , Jin LI , Feng ZHANG , Song LUO , CELLECTIS
发明人： Luc Mathis , Daniel F. Voytas , Jin Li , Feng Zhang , Song Luo
IPC分类号： C12N15/82
CPC分类号： C12N15/8213 , C12N15/8209 , C12N15/8274 , C12N15/8278
摘要： The present invention relates to methods allowing the targeted insertion of transgenes into a plant genome at desired loci by using homologous recombination combined with rare-cutting endonucleases without the need of inserting an exogenous selectable marker.
摘要翻译：本发明涉及通过使用与稀有切割内切核酸酶组合的同源重组而不需要插入外源选择性标记的方法，允许将转基因靶向插入到所需基因座的植物基因组中。

122. 发明授权

US09111815B2 Pixel structure, LCD panel, and manufacturing method thereof 有权
标题翻译：像素结构，LCD面板及其制造方法
公开(公告)号：US09111815B2
公开(公告)日：2015-08-18
申请号：US13478541
申请日：2012-05-23
申请人： Guanbao Hui , Seungjin Choi , Weifeng Zhou , Feng Zhang
发明人： Guanbao Hui , Seungjin Choi , Weifeng Zhou , Feng Zhang
IPC分类号： G02F1/1335 , H01L27/12 , G02F1/1368
CPC分类号： H01L27/1288 , G02F1/133345 , G02F1/133555 , G02F1/1368 , H01L27/1218 , H01L27/124 , H01L27/1262
摘要： An embodiment of the disclosed technology provides a pixel structure, comprising a TFT, a reflective region and a transmissive region, wherein the reflective region comprises a reflective region insulation layer, a reflection layer on the reflective region insulation layer and a reflective region pixel electrode on the reflection layer, and the transmissive region comprises a transmissive region pixel electrode, wherein the reflective region pixel electrode and the transmissive region pixel electrode form an integral structure, and the integral structure of the pixel electrodes is connected with the drain electrode of the TFT, wherein the organic layer in the reflective region is formed on an array substrate prior to a gate electrode of the TFT, and the reflection layer in the reflective region and the gate electrode of the TFT are formed in a same patterning process by using a same metal layer.
摘要翻译：所公开的技术的一个实施例提供了一种像素结构，包括TFT，反射区域和透射区域，其中反射区域包括反射区域绝缘层，反射区域绝缘层上的反射层和反射区域像素电极反射层和透射区域包括透射区域像素电极，其中反射区域像素电极和透射区域像素电极形成一体结构，并且像素电极的整体结构与TFT的漏极连接，其中反射区域中的有机层在TFT的栅电极之前形成在阵列衬底上，并且反射区域中的反射层和TFT的栅极电极通过使用相同的金属在相同的图案化工艺中形成层。

123. 发明授权

US08977660B1 Multi-level distributed hash table for data storage in a hierarchically arranged network 有权
标题翻译：用于分层布置网络中数据存储的多级分布式散列表
公开(公告)号：US08977660B1
公开(公告)日：2015-03-10
申请号：US13402329
申请日：2012-02-22
申请人： Qin Xin , Feng Zhang , Qi Bao
发明人： Qin Xin , Feng Zhang , Qi Bao
IPC分类号： G06F12/00 , G06F17/30 , H04N21/231
CPC分类号： H04N21/23103
摘要： An improved technique for distributed data storage employs multiple DHT (distributed hash table) rings provided at different levels of a network hierarchy. A computing node is identified for data storage by performing multiple hashing operations, one for each DHT ring. The hashing operations for the different rings are distinct in that they are performed using different hashing functions and/or are performed on different data sources. In one example, a 2-level DHT is formed from a group of LANs forming a first DHT ring and a group of computing nodes, within each LAN, forming a second DHT ring.
摘要翻译：用于分布式数据存储的改进技术使用在网络层级的不同级别提供的多个DHT（分布式哈希表）环。通过执行多个哈希操作来识别用于数据存储的计算节点，每个DHT环一个。不同环的散列操作是不同的，因为它们使用不同的散列函数执行和/或在不同数据源上执行。在一个示例中，2层DHT由形成第一DHT环的LAN组和每个LAN内的一组计算节点组成，形成第二DHT环。

124. 发明申请

US20150034212A1 Non-Oriented Electrical Steel Sheet with Fine Magnetic Performance, and Calcium Treatment Method Therefor 审中-公开
标题翻译：具有细磁性能的非取向电工钢板及其钙处理方法
公开(公告)号：US20150034212A1
公开(公告)日：2015-02-05
申请号：US14379529
申请日：2012-03-27
申请人： Feng Zhang , Xiandong Liu , Shishu Xie , Xuejun Lu , Xiao Chen , Aihua Ma , Peili Zhang , Yanwei Wang , Lan Zhang , Hongxu Hei
发明人： Feng Zhang , Xiandong Liu , Shishu Xie , Xuejun Lu , Xiao Chen , Aihua Ma , Peili Zhang , Yanwei Wang , Lan Zhang , Hongxu Hei
IPC分类号： H01F1/147 , C21C7/068 , C22C38/00 , C22C38/06 , C22C38/04 , C22C38/02 , C21C7/06 , C21C7/00
CPC分类号： H01F1/14775 , C21C7/0006 , C21C7/06 , C21C7/068 , C21C7/10 , C21D8/12 , C21D9/46 , C22C38/001 , C22C38/002 , C22C38/004 , C22C38/02 , C22C38/04 , C22C38/06 , H01F1/14766 , H01F1/14791 , H01F1/16
摘要： A non-oriented electrical steel sheet with fine magnetic performance, and a calcium treatment method therefor, including an RH (Ruhrstahl-Heraeus) refinement step. The RH refinement step sequentially comprises a decarbonization step, an aluminum deoxidation step, and a step of adding calcium alloy. In the step of adding calcium alloy, time when the calcium alloy is added satisfies the following condition: time interval between Al and Ca/total time after ΣAl=0.2-0.8. In this method, production cost is reduced, the production process is simple, a normal processing cycle of RH refinement is not affected, the device is convenient in operation and is controllable, and foreign substances are controllable in both shape and quantities. The non-oriented electrical steel sheet prepared according to the present invention has fine magnetic performance, and the method can be used for mass production of the non-oriented electrical steel sheet with fine magnetic performance.
摘要翻译：一种具有细磁性能的无取向电工钢板及其钙处理方法，包括RH（Ruhrstahl-Heraeus）精制步骤。 RH精炼步骤依次包括脱碳步骤，铝脱氧步骤和添加钙合金的步骤。在添加钙合金的步骤中，添加钙合金的时间满足以下条件：Al与Ca之间的时间间隔/ Al = 0.2-0.8之后的总时间。在这种方法中，生产成本降低，生产工艺简单，RH精加工的正常加工周期不受影响，设备操作方便，可控，异物在形状和数量上都是可控的。根据本发明制备的无取向电工钢板具有优良的磁性能，并且该方法可用于批量生产具有优良磁性能的无方向性电工钢板。

125. 发明授权

US08933195B2 Histone deacetylase inhibitors and synthetic method thereof and use thereof in manufacture of medicaments 有权
标题翻译：组蛋白脱乙酰酶抑制剂及其合成方法及其在药物制造中的应用
公开(公告)号：US08933195B2
公开(公告)日：2015-01-13
申请号：US13980308
申请日：2012-02-23
申请人： Sheng Jiang , Shang Li , Zhiyi Yao , Yiwu Yao , Feng Zhang , Yang Chao , Hai Ye , Min Chen
发明人： Sheng Jiang , Shang Li , Zhiyi Yao , Yiwu Yao , Feng Zhang , Yang Chao , Hai Ye , Min Chen
IPC分类号： C07K5/097 , C07F7/10 , C07F7/18 , A61K38/06
CPC分类号： C07K5/0821 , A61K38/06 , C07F7/10 , C07F7/1804 , Y02A50/411
摘要： The invention provides histone deacetylase (HDAC) inhibitors shown as Formula I, where R1 to R8 are as defined in the specification. The invention also provides methods for synthesis of these compounds and applications of these compounds in preparing pharmaceuticals for preventing or treating mammal diseases related to the dysregulation of HDAC.
摘要翻译：本发明提供如式I所示的组蛋白脱乙酰酶（HDAC）抑制剂，其中R1至R8如说明书中所定义。本发明还提供了这些化合物的合成方法和这些化合物在制备用于预防或治疗与HDAC失调相关的哺乳动物疾病的药物中的应用。

126. 发明授权

US08698149B2 Liquid crystal display and array substrate 有权
标题翻译：液晶显示器和阵列基板
公开(公告)号：US08698149B2
公开(公告)日：2014-04-15
申请号：US13457825
申请日：2012-04-27
申请人： Guanboa Hui , Seungjin Choi , Feng Zhang
发明人： Guanboa Hui , Seungjin Choi , Feng Zhang
IPC分类号： H01L31/00
CPC分类号： G02F1/136227 , G02F2001/134381 , H01L27/124 , H01L29/4908
摘要： An embodiment of the disclosed technology discloses an array substrate comprising: a base substrate; a first layer transparent common electrode formed on the base substrate; a gate metal common electrode formed on the first layer transparent common electrode; an insulation layer formed on the gate metal common electrode, with via holes being formed in the insulation layer; and a second layer transparent common electrode formed on the insulation layer. A side portion of via holes is in contact with the gate metal common electrode, another side portion is in contact with the first layer transparent common electrode, such that the second layer transparent common electrode is connected electrically with the first layer transparent common electrode and the gate metal common electrode in the via holes.
摘要翻译：所公开技术的一个实施例公开了一种阵列基板，包括：基底; 形成在所述基底基板上的第一层透明公共电极; 形成在第一层透明公共电极上的栅极金属共电极; 形成在所述栅极金属公共电极上的绝缘层，在所述绝缘层中形成有通孔; 以及形成在绝缘层上的第二层透明公共电极。通孔的侧部与栅极金属公共电极接触，另一侧部与第一层透明公共电极接触，使得第二层透明公共电极与第一层透明公共电极电连接，栅极金属公共电极在通孔中。

127. 发明授权

US08675672B1 Hierarchical cluster tree overlay network 有权
标题翻译：层次聚类树覆盖网络
公开(公告)号：US08675672B1
公开(公告)日：2014-03-18
申请号：US13341663
申请日：2011-12-30
申请人： Qi Bao , Feng Zhang , Qin Xin
发明人： Qi Bao , Feng Zhang , Qin Xin
IPC分类号： H04L12/28
CPC分类号： H04L45/64 , H04L45/46 , H04L45/7453
摘要： A Hierarchical Cluster Tree (HCT) overlay network reflects underlying physical network topology including inter-node distances (e.g., hop count), and an HCT structure groups nodes based on distance measurements. Local area networks (LANs) are basic building blocks. The network includes first and second level-1 clusters of LANs, each LAN including computerized data processing and/or storage nodes. A distance between LANs in the level-1 clusters is less than or equal to a predefined level-1 maximum distance. The LANs of the first and second level-1 clusters form a level-2 cluster of LANs in which a distance between cluster medoid nodes of the level-1 clusters is less than or equal to a predefined level-2 maximum distance greater than the level-1 maximum distance. Clustering can be extended to higher levels having successively greater maximum distances.
摘要翻译：分层聚簇树（HCT）覆盖网络反映了包括节点间距离（例如，跳数））的底层物理网络拓扑，并且HCT结构基于距离测量对节点进行分组。局域网（LAN）是基本的组成部分。该网络包括LAN的第一和第二一级集群，每个LAN包括计算机化的数据处理和/或存储节点。第1级群集中的LAN之间的距离小于或等于预定义的1级最大距离。第一级和第二级1集群的LAN形成一级的2级集群，其中级别1集群的集群中心节点之间的距离小于或等于大于等级的预定义的级别2最大距离 -1最大距离。聚类可以扩展到具有连续更大的最大距离的较高级别。

128. 发明授权

US08633186B2 Modulation of chemosensory receptors and ligands associated therewith 有权
标题翻译：与其相关的化学感应受体和配体的调节
公开(公告)号：US08633186B2
公开(公告)日：2014-01-21
申请号：US12663634
申请日：2008-06-03
申请人： Catherine Tachdjian , Donald S. Karanewsky , Xiao-Qing Tang , Xiaodong Li , Feng Zhang , Guy Servant , Qing Chen , Vincent Darmohusodo , Richard Fine , Joseph R. Fotsing , Jeffrey Robert Hammaker , Xinshan Kang , Rachel D. A. Kimmich , Boris Klebansky , Haitian Liu , Goran Petrovic , Marketa Rinnova , Sara Adamski-Werner , Jeffrey Yamamoto , Hong Zhang , Albert Zlotnik , Karen Zoller
发明人： Catherine Tachdjian , Donald S. Karanewsky , Xiao-Qing Tang , Xiaodong Li , Feng Zhang , Guy Servant , Qing Chen , Vincent Darmohusodo , Richard Fine , Joseph R. Fotsing , Jeffrey Robert Hammaker , Xinshan Kang , Rachel D. A. Kimmich , Boris Klebansky , Haitian Liu , Goran Petrovic , Marketa Rinnova , Sara Adamski-Werner , Jeffrey Yamamoto , Hong Zhang , Albert Zlotnik , Mark Zoller
IPC分类号： C07D239/95 , C07D285/16 , A61K31/517 , A61K31/54
CPC分类号： A61K31/495 , A61K31/517 , A61K31/519 , C07D239/80 , C07D239/93 , C07D239/95 , C07D239/96 , C07D285/15 , C07D405/12 , C07D417/04 , C07D417/12 , C07D487/04 , C07D491/04 , C07D495/04 , C07D495/14 , C07D513/04 , C07D513/20 , C07H17/00 , G01N33/74 , G01N2333/726 , G01N2500/00 , G01N2500/04 , G06F19/16 , G06F19/18
摘要： The present invention includes methods for identifying modifiers of chemosensory receptors and their ligands, e.g., by determining whether a test entity is suitable to interact with one or more interacting sites within the Venus flytrap domains of the chemosensory receptors, and modifiers capable of modulating chemosensory receptors and their ligands. The present invention also includes modifiers of chemosensory receptors and their ligands having Formula (I), its subgenus, and specific compounds. Furthermore, the present invention includes ingestible compositions comprising the modifiers of chemosensory receptors and their ligands and methods of using the modifiers of chemosensory receptors and their ligands to enhance the sweet taste of an ingestible composition or treat a condition associated with a chemosensory receptor. In addition, the present invention include processes for preparing the modifiers of chemosensory receptors and their ligands.
摘要翻译：本发明包括用于鉴定化学感受器及其配体的调节剂的方法，例如通过确定测试实体是否适合与化学感应受体的金星蝇捕获区域内的一个或多个相互作用位点相互作用，以及能够调节化学感应受体及其配体。本发明还包括具有式（I），其亚属和特定化合物的化学感应受体及其配体的改性剂。此外，本发明包括含有化学感应受体调节剂及其配体的可摄入组合物，以及使用化学感应受体及其配体改性剂增强可摄入组合物的甜味或治疗与化学感觉受体相关的病症的方法。此外，本发明包括制备化学感受器及其配体的改性剂的方法。

129. 发明授权

US08592755B2 Method of switching ports of a switching valve of a gas chromatography-mass spectrometry apparatus 有权
标题翻译：切换气相色谱 - 质谱仪的切换阀的端口的方法
公开(公告)号：US08592755B2
公开(公告)日：2013-11-26
申请号：US13609301
申请日：2012-09-11
申请人： Hongliang Lu , Kai Lin , Jing Yu , Feng Zhang
发明人： Hongliang Lu , Kai Lin , Jing Yu , Feng Zhang
IPC分类号： H01J49/04
CPC分类号： G01N30/20 , G01N30/468 , G01N30/72 , G01N2030/201 , G01N2030/202
摘要： A method of operating a switching valve of a GC-MS apparatus is provided with installing a sample injector; connecting a first capillary column downstream of the sample injector; installing a heart-cutting unit downstream of the first capillary column; installing a first interconnecting column and a second capillary column to the heart-cutting unit respectively; connecting a switching valve to the heart-cutting unit via a first interconnecting column and a second capillary column respectively wherein the switching valve includes a plurality of ports; connecting the switching valve to an MS via a second interconnecting column; and switching ports to create different sample loops for passing compounds from the heart-cutting unit to the MS or passing compounds from the heart-cutting unit to the discharge column to be purged.
摘要翻译：操作GC-MS装置的切换阀的方法设置有安装样品注射器; 将样品注射器下游的第一毛细管柱连接; 在第一毛细管柱下游安装心脏切割单元; 将第一互连柱和第二毛细管柱分别安装到心切单元上; 分别经由第一互连柱和第二毛细管柱将切换阀连接到心切单元，其中切换阀包括多个端口; 通过第二互连柱将切换阀连接到MS; 和切换端口以创建不同的样品环，用于将化合物从心脏切割单元传递到MS或将化合物从心脏切割单元传递到排出柱以进行清除。

130. 发明授权

US08586363B2 TAL effector-mediated DNA modification 有权
标题翻译： TAL效应物介导的DNA修饰
公开(公告)号：US08586363B2
公开(公告)日：2013-11-19
申请号：US12965590
申请日：2010-12-10
申请人： Daniel F. Voytas , Adam Bogdanove , Feng Zhang , Michelle Christian , Tomas Cermak , Clarice Lauer Schmidt , Erin Doyle , Li Wang
发明人： Daniel F. Voytas , Adam Bogdanove , Feng Zhang , Michelle Christian , Tomas Cermak , Clarice Lauer Schmidt , Erin Doyle , Li Wang
IPC分类号： C12N15/00 , A01K67/00 , A01H9/00
CPC分类号： C12N9/22 , C12N15/01 , C12N15/102 , C12N15/1082 , C12N15/62 , C12N15/63 , C12Y301/21004
摘要： Materials and Methods related to gene targeting (e.g., gene targeting with transcription activator-like effector nucleases; “TALENS”) are provided.
摘要翻译：提供与基因靶向相关的材料和方法（例如，用转录激活子样效应核酸酶进行基因靶向;“TALENS”）。

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