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111. 发明授权

US07919910B2 Medical balloon incorporating electroactive polymer and methods of making and using the same 有权
标题翻译：含有电活性聚合物的医用气囊及其制造和使用方法
公开(公告)号：US07919910B2
公开(公告)日：2011-04-05
申请号：US12858020
申请日：2010-08-17
申请人： Tracee Eidenschink , Derek Wise , Derek Sutermeister , Yousef Alkhatib , Daniel Gregorich , Adam Jennigs , Matt Heidner , Dominick Godin , Richard C. Gunderson , John Blix , Karl A. Jagger , Angela Kornkven Volk
发明人： Tracee Eidenschink , Derek Wise , Derek Sutermeister , Yousef Alkhatib , Daniel Gregorich , Adam Jennigs , Matt Heidner , Dominick Godin , Richard C. Gunderson , John Blix , Karl A. Jagger , Angela Kornkven Volk
IPC分类号： H01L41/09 , A61M29/00
CPC分类号： A61M25/104 , A61M25/1038 , A61M2025/0058 , A61M2025/1031 , A61M2025/1081 , A61M2025/1086 , A61M2025/1088 , Y10S310/80
摘要： An expandable medical balloon having at least one static state, at least one expanded state, and at least one deflated state, the expandable medical balloon including at least one active region, the at least one active region including electroactive polymer.
摘要翻译：一种具有至少一种静态，至少一种膨胀状态和至少一种放气状态的可膨胀医用气囊，所述可扩张医用气囊包括至少一个活性区，所述至少一个活性区包括电活性聚合物。

112. 发明申请

US20100312322A1 Medical Balloon Incorporating Electroactive Polymer and Methods of Making and Using the Same 有权
标题翻译：包含电聚合物的医用气囊及其制造和使用方法
公开(公告)号：US20100312322A1
公开(公告)日：2010-12-09
申请号：US12858020
申请日：2010-08-17
申请人： Tracee Eidenschink , Derek Wise , Derek Sutermeister , Yousef Alkhatib , Daniel Gregorich , Adam Jennings , Matt Heidner , Dominick Godin , Richard C. Gunderson , John Blix , Karl A. Jagger , Angela Kornkven Volk
发明人： Tracee Eidenschink , Derek Wise , Derek Sutermeister , Yousef Alkhatib , Daniel Gregorich , Adam Jennings , Matt Heidner , Dominick Godin , Richard C. Gunderson , John Blix , Karl A. Jagger , Angela Kornkven Volk
IPC分类号： A61F2/84 , A61M29/02
CPC分类号： A61M25/104 , A61M25/1038 , A61M2025/0058 , A61M2025/1031 , A61M2025/1081 , A61M2025/1086 , A61M2025/1088 , Y10S310/80
摘要： An expandable medical balloon having at least one static state, at least one expanded state, and at least one deflated state, the expandable medical balloon including at least one active region, the at least one active region including electroactive polymer.
摘要翻译：一种具有至少一种静态，至少一种膨胀状态和至少一种放气状态的可膨胀医用气囊，所述可扩张医用气囊包括至少一个活性区，所述至少一个活性区包括电活性聚合物。

113. 发明申请

US20100145437A1 Stent Design Allowing Extended Release of Drug and/or Enhanced Adhesion of Polymer to OD Surface 审中-公开
标题翻译：支架设计允许药物的扩展释放和/或增强的聚合物粘附到OD表面
公开(公告)号：US20100145437A1
公开(公告)日：2010-06-10
申请号：US12706881
申请日：2010-02-17
申请人： Timothy S. Girton , Jeffrey S. Lindquist , David M. Knapp , Matt Heidner , Daniel Gregorich , Umang Anand , Peter Edelman , Matthew J. Miller , Raed Rizq , Jan Weber , Tracee Eidenschink , John J. Chen , Jaykeep Y. Kokate , Aparna Bhave , Kent D. Harrison , Graig L. Kveen , Benjamin Arcand , Michael Kuchling
发明人： Timothy S. Girton , Jeffrey S. Lindquist , David M. Knapp , Matt Heidner , Daniel Gregorich , Umang Anand , Peter Edelman , Matthew J. Miller , Raed Rizq , Jan Weber , Tracee Eidenschink , John J. Chen , Jaykeep Y. Kokate , Aparna Bhave , Kent D. Harrison , Graig L. Kveen , Benjamin Arcand , Michael Kuchling
IPC分类号： A61F2/82
CPC分类号： A61F2/91 , A61F2210/0076 , A61F2220/0066 , A61F2220/0083 , A61F2250/0067 , A61F2250/0068
摘要： The invention is directed to mechanisms and methods that reduce the delamination of a therapeutic agent from a stent. The mechanisms include holes (channels, wells, and other hole configurations), protrusions, sintered metal cores, clamps/staples, pins, and stainless steel shields.
摘要翻译：本发明涉及减少治疗剂从支架分层的机制和方法。这些机构包括孔（通道，孔和其他孔构造），突起，烧结金属芯，夹/钉，销和不锈钢屏蔽。

114. 发明申请

US20100022949A1 BALLOON ASSEMBLY WITH A TORQUE 有权
标题翻译：带扭矩的气球装配
公开(公告)号：US20100022949A1
公开(公告)日：2010-01-28
申请号：US12574073
申请日：2009-10-06
申请人： Tracee Eidenschink
发明人： Tracee Eidenschink
IPC分类号： A61M29/00
CPC分类号： A61M25/1002 , A61M25/10 , A61M25/1027 , A61M25/1038
摘要： An expandable medical balloon for use in combination with a catheter assembly, the balloon having a torque in a first and second unexpanded state, and to methods of making and using the same.
摘要翻译：一种用于与导管组件组合使用的可膨胀的医用气囊，所述球囊具有处于第一和第二未展开状态的扭矩，以及制造和使用该气囊的方法。

115. 发明申请

US20090318994A1 TRANSVASCULAR BALLOON CATHETER WITH PACING ELECTRODES ON SHAFT 审中-公开
标题翻译：带横断面电极的透射式气泡导管
公开(公告)号：US20090318994A1
公开(公告)日：2009-12-24
申请号：US12484778
申请日：2009-06-15
申请人： Tracee Eidenschink , Richard J. Olson
发明人： Tracee Eidenschink , Richard J. Olson
IPC分类号： A61N1/05 , A61N1/362
CPC分类号： A61N1/056 , A61B2017/22001 , A61B2017/22051 , A61B2017/320716 , A61M25/005 , A61M25/0068 , A61M25/0082 , A61M25/09 , A61M25/10 , A61M25/104 , A61M2025/0004 , A61M2025/0096 , A61M2025/09183 , A61M2025/1086 , A61M2025/1093 , A61N1/3627
摘要： Cardioprotective pacing is applied to prevent and/or reduce cardiac injury associated with myocardial infarction (MI) and revascularization procedure. Pacing pulses are generated from a pacemaker and delivered through one or more pacing electrodes incorporated onto one or more percutaneous transluminal vascular intervention (PTVI) devices during the revascularization procedure. In one embodiment, at least one pacing electrode is incorporated onto the shaft of a PTVI device to allow the pacing pulses to be delivered to a site remote from an infarcted region where the distal end portion of the PTVI device is placed.
摘要翻译：心脏保护起搏应用于预防和/或减少与心肌梗塞（MI）和血运重建术相关的心脏损伤。起搏脉冲由起搏器产生，并通过在血运重建过程中并入一个或多个经皮腔内血管介入（PTVI）装置的一个或多个起搏电极输送。在一个实施例中，至少一个起搏电极并入到PTVI装置的轴上，以允许起搏脉冲被输送到远离PTVI装置的远端部分的梗死区域的位置。

116. 发明申请

US20090312830A1 Balloon arc profile control 审中-公开
标题翻译：气球弧形控制
公开(公告)号：US20090312830A1
公开(公告)日：2009-12-17
申请号：US12214253
申请日：2008-06-17
申请人： Sean McNulty , David Broman , Matthew Heidner , Tracee Eidenschink
发明人： Sean McNulty , David Broman , Matthew Heidner , Tracee Eidenschink
IPC分类号： A61F2/06
CPC分类号： A61F2/958 , A61F2002/9583
摘要： The present invention is directed to a delivery system including a stent protector to protect an end of the stent and/or stent body for delivery of the stent to an intended fixation site or treatment site within a body lumen. More specifically, the present invention is directed to balloon catheter which protects the distal end, proximal end and/or body of a stent during delivery to the deployment site and/or shipping of a preloaded system.
摘要翻译：本发明涉及一种输送系统，其包括支架保护器，用于保护支架和/或支架主体的端部，用于将支架输送到体腔内的预期固定部位或治疗部位。更具体地，本发明涉及一种球囊导管，其在输送到展开部位和/或运送预加载的系统期间保护支架的远端，近端和/或主体。

117. 发明申请

US20090018635A1 STENT PROTECTOR 审中-公开
标题翻译： STENT保护器
公开(公告)号：US20090018635A1
公开(公告)日：2009-01-15
申请号：US11775340
申请日：2007-07-10
申请人： Thomas J. Holman , Tracee Eidenschink
发明人： Thomas J. Holman , Tracee Eidenschink
IPC分类号： A61F2/84 , B65D69/00
CPC分类号： A61F2/958 , A61F2002/9586 , A61F2002/9665 , A61F2250/0039 , A61F2250/0059 , A61F2250/0071
摘要： A method for providing a catheter assembly with a protective sleeve for a stent delivery system wherein the protective sleeve has a removable portion that is removed from about the stent before the system is inserted into a patient, and the protective sleeve made thereby.
摘要翻译：一种用于为导管组件提供用于支架输送系统的保护套管的方法，其中所述保护套管具有在所述系统插入患者体内之前从所述支架周围移除的可移除部分，并且由此制成所述保护套筒。

118. 发明申请

US20080281395A1 RATCHETING BIO CELL DESIGNS 审中-公开
标题翻译：刺激生物细胞设计
公开(公告)号：US20080281395A1
公开(公告)日：2008-11-13
申请号：US11745091
申请日：2007-05-07
申请人： Tracee Eidenschink , Todd Bethel , Thomas E. Broome , Gordon J. Kocur , Jens Hegg , Michael P. Meyer
发明人： Tracee Eidenschink , Todd Bethel , Thomas E. Broome , Gordon J. Kocur , Jens Hegg , Michael P. Meyer
IPC分类号： A61F2/06
CPC分类号： A61F2/856 , A61F2/91 , A61F2/915 , A61F2002/30062 , A61F2002/30329 , A61F2002/91591 , A61F2210/0004 , A61F2220/0025 , A61F2250/0031
摘要： A bifurcated stent having a side branch constructed out of a bioabsorbable material. The side branch comprises one or more bio cells which are flexible and easily deformable when the stent is in the unexpanded state. The bio cells have a locking member which fixedly holds the bio cells in place once the stent assumes the expanded state. The locking member uses oppositely directed hooks or ratchet teeth to prevent contraction in the bio cells once the expanded state is assumed. By having an appropriate alternation between flexibility and rigidity the side branch is flexible enough to deal with the geometric difficulties of bending and deploying a side branch while being fixed and rigid enough to properly support and scaffold a side branch assembly. The deployment of the side branch can be facilitated by the use of a ratcheting device. The side branch can also have a flared shape.
摘要翻译：具有由生物可吸收材料构成的侧分支的分叉支架。侧分支包括一个或多个生物细胞，其在支架处于未膨胀状态时是柔性的并且易于变形。生物细胞具有锁定构件，一旦支架呈现膨胀状态，该锁定构件将生物细胞固定地保持就位。一旦展开状态，锁定件就使用相反方向的钩或棘齿来防止生物细胞的收缩。通过在柔性和刚度之间具有适当的交替性，侧分支具有足够的灵活性，以应对弯曲和展开侧分支的几何困难，同时固定和刚性足以适当地支撑和支架侧分支组件。通过使用棘轮装置可以促进侧支的部署。侧枝也可以具有喇叭形状。

119. 发明申请

US20080275426A1 Flexible and Durable Tip 审中-公开
标题翻译：灵活和耐用的提示
公开(公告)号：US20080275426A1
公开(公告)日：2008-11-06
申请号：US11743753
申请日：2007-05-03
申请人： Thomas J. HOLMAN , Tracee Eidenschink , John J. Chen , Daniel J. Horn
发明人： Thomas J. HOLMAN , Tracee Eidenschink , John J. Chen , Daniel J. Horn
IPC分类号： A61M25/16
CPC分类号： A61M25/104 , A61M25/001 , A61M25/0069 , A61M25/1006 , A61M2025/1093
摘要： A method of making a flexible, durable catheter tip is achieved by providing a catheter tip, and in some embodiments, applying heat energy only to the distal portion of a catheter tip. In other embodiments, the method includes ablating a portion of the outer diameter of the proximal region material. In at least one embodiment, the method includes manufacturing a catheter tip with a layer of a harder material disposed about a first layer of a relatively softer material and then ablating at least a portion of the harder material. In some embodiments, the method includes dipping at least a portion of the distal region of the catheter tip into a chemical bath. In some embodiments, the method includes providing a catheter tip made of a tip material, adding a curable adhesive to at least a portion of the distal region, and then applying heat energy to cure the curable adhesive.
摘要翻译：通过提供导管尖端来实现制造柔性，耐久的导管尖端的方法，并且在一些实施例中，仅将热能施加到导管尖端的远端部分。在其他实施例中，该方法包括烧蚀近端区域材料的外径的一部分。在至少一个实施例中，该方法包括制造具有设置在相对较软材料的第一层周围的较硬材料层的导管末端，然后再烧蚀至少一部分较硬的材料。在一些实施例中，该方法包括将导管尖端的远端区域的至少一部分浸入化学浴中。在一些实施例中，该方法包括提供由尖端材料制成的导管末端，将可固化粘合剂添加到远侧区域的至少一部分，然后施加热能以固化可固化粘合剂。

120. 发明申请

US20080051830A1 Occluding device and method 审中-公开
标题翻译：封闭装置和方法
公开(公告)号：US20080051830A1
公开(公告)日：2008-02-28
申请号：US11509135
申请日：2006-08-24
申请人： Tracee Eidenschink , Karl A. Jagger , Daniel Tomaschko
发明人： Tracee Eidenschink , Karl A. Jagger , Daniel Tomaschko
IPC分类号： A61B17/08
CPC分类号： A61B17/0057 , A61B17/12022 , A61B17/12122 , A61B17/12159 , A61B17/12172 , A61B17/12186 , A61B17/12195 , A61B2017/00575 , A61B2017/00579 , A61B2017/00592 , A61B2017/00606 , A61B2017/1205
摘要： The present disclosure relates generally to devices and methods for use with cardiac defects, more particularly, the present disclosure relates to a device including a frame defining a lumen, where the frame expands from a first configuration to a second configuration larger than the first configuration. The device also includes an anchoring member extending from the frame to secure the frame while in the second configuration and a plug portion of the frame to occlude at least a portion of the lumen.
摘要翻译：本公开一般涉及用于心脏缺陷的装置和方法，更具体地，本公开涉及包括限定腔的框架的装置，其中框架从第一构型扩展到大于第一构型的第二构造。该装置还包括从框架延伸的固定构件，以在第二构型中固定框架，并且框架的插塞部分闭塞管腔的至少一部分。

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