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111. 发明申请

US20070207098A1 Antioxidant, Whitening Agent And External Preparation For Skin Using The Same 失效
标题翻译：抗氧化剂，美白剂及外用皮肤使用方法
公开(公告)号：US20070207098A1
公开(公告)日：2007-09-06
申请号：US10571206
申请日：2004-09-10
申请人： Takeshi Nawamura , Nobuhiko Ochiai , Masato Hatao , Mineyuki Yokoyama , Koji Kobayashi , Fumio Eguchi
发明人： Takeshi Nawamura , Nobuhiko Ochiai , Masato Hatao , Mineyuki Yokoyama , Koji Kobayashi , Fumio Eguchi
IPC分类号： A61K36/09 , A61K8/97
CPC分类号： A61K36/07 , A61K8/9706 , A61K2800/522 , A61K2800/782 , A61Q19/02 , A61Q19/08
摘要： The present invention provides an antioxidant and a whitening agent having high safety, and a external preparation for skin using the same. The antioxidant and whitening agent comprise, as an effective component, one or more extracts from Basidiomycetes selected from the group consisting of Pleurotus abalonus, Pholiota squarrosa, Onnia orientalis, Astraeus hygrometricus and Pleurotus nebrodensis. These extracts have a free radical capturing ability and are useful for suppressing skin oxidation and for preventing and improving skin aging. In addition, the extracts have a tyrosinase activity inhibiting action and can suppress the melanin generation. Since the fruit bodies of these Basidiomycetes have been used for edible purpose and have high safety, they can be used preferably for an external preparation for skin.
摘要翻译：本发明提供了具有高安全性的抗氧化剂和增白剂，以及使用其的皮肤外用剂。抗氧化剂和增白剂作为有效成分包含一种或多种从担子菌中提取的提取物，所述提取物选自侧耳属（Pleurotus abalonus），Pholiota squarrosa，Onnia orientalis，Astraeus hygrometricus和Pleurotus nebrodensis。这些提取物具有自由基捕获能力，可用于抑制皮肤氧化和预防和改善皮肤老化。此外，提取物具有酪氨酸酶活性抑制作用，能够抑制黑色素的产生。由于这些担子菌的果实体已被用于食用，安全性高，所以可以优选用于皮肤外用剂。

112. 发明申请

US20070172444A1 Hair tonics and method of screening the same 审中-公开
标题翻译：发质和筛选方法相同
公开(公告)号：US20070172444A1
公开(公告)日：2007-07-26
申请号：US11649279
申请日：2007-01-04
申请人： Toshihiko Hibino , Yumiko Tsuji , Tsutomu Soma , Sumiko Denda , Jotaro Nakanishi , Tadahito Takahashi , Kenichi Umishio , Koji Kobayashi
发明人： Toshihiko Hibino , Yumiko Tsuji , Tsutomu Soma , Sumiko Denda , Jotaro Nakanishi , Tadahito Takahashi , Kenichi Umishio , Koji Kobayashi
IPC分类号： A61K8/97 , A61K36/82 , A61K36/899 , A61K36/48 , A61K36/87
CPC分类号： A61Q5/00 , A61K8/498 , A61K8/64 , A61K8/97 , A61K31/366 , A61K36/185 , A61K36/30 , A61K36/48 , A61K36/53 , A61K36/73 , A61K36/82 , A61K36/87 , A61K36/8994 , A61K38/06 , A61K38/55 , A61K45/06 , A61K2800/782 , A61Q7/00 , A61K2300/00
摘要： There is provided a hair tonic comprising at least two of an inhibitor against 5α reductase type 2, an inhibitor against transforming growth factor β2, and an inhibitor against caspase-3; a method comprising screening for at least two of inhibition against 5α reductase type 2, inhibition against transforming growth factor β2, and inhibition against caspase-3, or comprising screening for inhibition against caspase-3 and then for apoptosis inhibition, and a hair loss inhibitor having the effect of inhibiting caspase-3, and a hair loss inhibitor having the effect of inhibiting caspase-3 and of inhibiting apoptosis.
摘要翻译：提供了包含至少两种抑制剂5型5α还原酶2型抑制剂，抗转化生长因子β2的抑制剂和抗半胱天冬酶-3抑制剂的滋补剂; 一种方法包括筛选至少两种对2型5α还原酶的抑制，对转化生长因子β2的抑制和对半胱天冬酶-3的抑制，或包括筛选对半胱天冬酶-3的抑制，然后筛选凋亡抑制，以及脱发抑制剂具有抑制半胱天冬酶-3的效果，以及具有抑制半胱天冬酶-3的作用并抑制细胞凋亡的脱发抑制剂。

113. 发明授权

US07175101B2 Thermostat mounting structure 有权
标题翻译：恒温器安装结构
公开(公告)号：US07175101B2
公开(公告)日：2007-02-13
申请号：US10796039
申请日：2004-03-10
申请人： Ryuji Moriyama , Koji Kobayashi , Toyoyuki Yogo , Kenji Oki
发明人： Ryuji Moriyama , Koji Kobayashi , Toyoyuki Yogo , Kenji Oki
IPC分类号： G05D23/00 , F01P7/14 , F01P1/04
CPC分类号： G05D23/1333 , F01P7/16 , F01P2070/00
摘要： A thermostat mounting structure capable of reliably positioning an embedded thermostat and ensuring high sealability. A coolant channel is formed in a casing. An embedding hole is formed in the casing across the coolant channel. A thermostat includes a cylindrical valve body with a surrounding wall having an entry aperture and an exit aperture. A valving element for advancing and retracting to open and close the entry aperture and the exit aperture. The thermostat is inserted into the embedding hole so that both apertures face the coolant channel. A cover member for covering the embedding hole via a circular rubber seal seated in a groove of the cover member and for fixing the thermostat. A positioning structure for positioning the thermostat to a side of the cover member.
摘要翻译：恒温器安装结构，能够可靠地定位嵌入式恒温器并确保高密封性。冷却剂通道形成在壳体中。在套管中形成一个嵌入孔穿过冷却剂通道。恒温器包括具有带入口孔和出口孔的周围壁的圆柱形阀体。用于前进和后退以打开和关闭入口孔和出口孔的阀元件。恒温器插入到嵌入孔中，使得两个孔面对冷却剂通道。盖构件，用于通过位于盖构件的凹槽中的环形橡胶密封件覆盖嵌入孔并固定恒温器。一种定位结构，用于将恒温器定位在盖构件的一侧。

114. 发明申请

US20070030978A1 Apparatus and method for measuring sound field 有权
标题翻译：用于测量声场的装置和方法
公开(公告)号：US20070030978A1
公开(公告)日：2007-02-08
申请号：US11496474
申请日：2006-08-01
申请人： Yasuyuki Kino , Akira Sakamoto , Tokihiko Sawashi , Koji Kobayashi , Masahiro Okuno
发明人： Yasuyuki Kino , Akira Sakamoto , Tokihiko Sawashi , Koji Kobayashi , Masahiro Okuno
IPC分类号： H04R29/00
CPC分类号： H04S7/30 , G01H5/00 , H04R29/00 , H04R2499/13 , H04S7/307
摘要： A sound field measurement apparatus includes a signal generating unit for outputting a burst signal, a driving unit for driving a speaker using the burst signal, a microphone for picking up an audio output from the speaker, an analog-digital converter for performing analog-digital conversion processing on an output signal from the microphone and outputting picked-up audio data, a filtering unit for performing filtering processing on the picked-up audio data, and an analyzing unit for determining a propagation time of the audio output from the speaker to the microphone in accordance with data output from the filtering unit. In this sound field measuring apparatus, the filtering unit is an IIR filter configured to filter the picked-up audio data forward and then backward along a time axis, or an IIR filter configured to filter the picked-up audio data backward and then forward along the time axis.
摘要翻译：声场测量装置包括用于输出脉冲串信号的信号产生单元，用于使用脉冲串信号驱动扬声器的驱动单元，用于拾取来自扬声器的音频输出的麦克风，用于执行模拟数字对来自麦克风的输出信号进行转换处理并输出拾取音频数据;滤波单元，用于对所拾取的音频数据进行滤波处理;以及分析单元，用于确定从扬声器输出的音频的传播时间麦克风根据过滤单元输出的数据。在该声场测量装置中，滤波单元是被配置为沿着时间轴向前，然后向后过滤所拾取的音频数据的IIR滤波器，或者被配置为向后过滤所拾取的音频数据然后向前沿时间轴。

115. 发明授权

US07110737B2 Audio equipment and control method of audio equipment 有权
标题翻译：音响设备音响设备及控制方法
公开(公告)号：US07110737B2
公开(公告)日：2006-09-19
申请号：US10428184
申请日：2003-04-30
申请人： Tokihiko Sawashi , Toshiaki Kobayashi , Koji Kobayashi
发明人： Tokihiko Sawashi , Toshiaki Kobayashi , Koji Kobayashi
IPC分类号： H04B1/06
CPC分类号： H04B15/04 , H04B2215/065
摘要： Audio equipment and a method of controlling audio equipment include a switching power amplifier circuit and a controller controlling a switching frequency of the power amplifier circuit. The controller varies the switching frequency of the power amplifier circuit in accordance with a receiving frequency in a case of receiving at least a medium-wave broadcast wave.
摘要翻译：音频设备和控制音频设备的方法包括开关功率放大器电路和控制功率放大器电路的开关频率的控制器。在接收至少中波广播波的情况下，控制器根据接收频率来改变功率放大器电路的开关频率。

116. 发明申请

US20060158532A1 Image capturing apparatus and image capturing method 有权
公开(公告)号：US20060158532A1
公开(公告)日：2006-07-20
申请号：US11334359
申请日：2006-01-19
申请人： Kenichiro Ayaki , Koji Kobayashi
发明人： Kenichiro Ayaki , Koji Kobayashi
IPC分类号： H04N5/235
CPC分类号： H04N5/2352
摘要： An image signal obtained by a CCD image sensor is amplified by an amplifier. A gain of the amplifier is changed according to an ISO sensitivity. An AE circuit measures light intensity of a subject. According to the measured light intensity, a correct exposure time of the CCD image sensor is calculated. The exposure time of the CCD image sensor is changed by a CCD driver. In the exposure adjustment, a system controller increases the gain by making the ISO sensitivity higher such that the calculated exposure time becomes shorter than a predetermined anti-camera shake exposure time.

117. 发明申请

US20060153794A1 Hair tonics and method of screening the same 审中-公开
标题翻译：发质和筛选方法相同
公开(公告)号：US20060153794A1
公开(公告)日：2006-07-13
申请号：US11312549
申请日：2005-12-21
申请人： Toshihiko Hibino , Yumiko Tsuji , Tsutomu Soma , Sumiko Denda , Jotaro Nakanishi , Tadahito Takahashi , Kenichi Umishio , Koji Kobayashi
发明人： Toshihiko Hibino , Yumiko Tsuji , Tsutomu Soma , Sumiko Denda , Jotaro Nakanishi , Tadahito Takahashi , Kenichi Umishio , Koji Kobayashi
IPC分类号： A61K8/97 , A61K36/185
CPC分类号： A61Q5/00 , A61K8/498 , A61K8/64 , A61K8/97 , A61K31/366 , A61K36/185 , A61K36/30 , A61K36/48 , A61K36/53 , A61K36/73 , A61K36/82 , A61K36/87 , A61K36/8994 , A61K38/06 , A61K38/55 , A61K45/06 , A61K2800/782 , A61Q7/00 , A61K2300/00
摘要： There is provided a hair tonic comprising at least two of an inhibitor against 5α reductase type 2, an inhibitor against transforming growth factor β2, and an inhibitor against caspase-3; a method comprising screening for at least two of inhibition against 5α reductase type 2, inhibition against transforming growth factor β2, and inhibition against caspase-3, or comprising screening for inhibition against caspase-3 and then for apoptosis inhibition, and a hair loss inhibitor having the effect of inhibiting caspase-3, and a hair loss inhibitor having the effect of inhibiting caspase-3 and of inhibiting apoptosis.
摘要翻译：提供了包含至少两种抑制剂5型5α还原酶2型抑制剂，抗转化生长因子β2的抑制剂和抗半胱天冬酶-3抑制剂的滋补剂; 一种方法包括筛选至少两种对2型5α还原酶的抑制，对转化生长因子β2的抑制和对半胱天冬酶-3的抑制，或包括筛选对半胱天冬酶-3的抑制，然后筛选凋亡抑制，以及脱发抑制剂具有抑制半胱天冬酶-3的效果，以及具有抑制半胱天冬酶-3的作用并抑制细胞凋亡的脱发抑制剂。

118. 发明申请

US20060107253A1 Method and apparatus for generating specification data 有权
标题翻译：用于生成规格数据的方法和装置
公开(公告)号：US20060107253A1
公开(公告)日：2006-05-18
申请号：US11065711
申请日：2005-02-25
申请人： Shin-ichi Sano , Hiroshi Sunaga , Koji Kobayashi
发明人： Shin-ichi Sano , Hiroshi Sunaga , Koji Kobayashi
IPC分类号： G06F9/44
CPC分类号： G06F8/10
摘要： When a source program written in Java or the like and using methods of BigDecimal class, a priority conforming to a predetermined arithmetic rule is identified for an arithmetic operational method included in an arithmetic operation statement, and the arithmetic operational method and the identified priority are registered into a storage device. Then, in a case where it is judged based on data stored in the storage device that a plurality of arithmetic operational methods are included in an arithmetic operational statement, and an arithmetic operational method with low priority is defined as an instance of an arithmetic operational method with high priority, following processing is carried out to generate specification data, that is, the arithmetic operational method with low priority and an instance and argument of the arithmetic operational method with low priority are converted into a first subexpression using an arithmetic operational sign in accordance with a predetermined rule. Then, parentheses representing that the arithmetic operation are carried out with priority is added to the first subexpression. In addition, the arithmetic operational method with high priority and an argument of the arithmetic operational method with high priority are converted into a second subexpression using an arithmetic operational sign in accordance with the predetermined rule. Finally, the second subexpression is linked with the first subexpression.
摘要翻译：当使用Java等编写并使用BigDecimal类的方法的源程序时，针对包括在算术运算语句中的算术运算方法来识别符合预定算术规则的优先级，并且记录算术运算方法和识别的优先级进入存储设备。然后，在根据存储装置中存储的数据判断在算术运算语句中包含多种算术运算方法的情况下，将低优先级的算术运算方法定义为算术运算方式的一例高优先级，进行以下处理以生成指定数据，即具有低优先级的算术运算方法，并且具有低优先级的算术运算方法的实例和自变量根据算术运算符号转换为第一子表达式具有预定规则。然后，代表优先执行算术运算的括号被加到第一子表达式中。此外，具有高优先级的算术运算方法和具有高优先级的算术运算方法的自变量根据预定规则被转换为使用算术运算符号的第二子表达式。最后，第二个子表达式与第一个子表达式相关联。

119. 发明申请

US20050148474A1 Plant activator 审中-公开
标题翻译：植物激活剂
公开(公告)号：US20050148474A1
公开(公告)日：2005-07-07
申请号：US11058368
申请日：2005-02-16
申请人： Mineyuki Yokoyama , Shoko Yamaguchi , Toshii Iida , Kiyotaka Kojima , Koji Kobayashi , Osamu Tanaka
发明人： Mineyuki Yokoyama , Shoko Yamaguchi , Toshii Iida , Kiyotaka Kojima , Koji Kobayashi , Osamu Tanaka
IPC分类号： A01N37/42 , A01N37/00
CPC分类号： A01N37/42
摘要： An object of the present invention is to determine novel means of activating plants; more particularly, means or controlling plant growth, such as means of promoting growth, means of controlling dormancy, means of imparting tolerance against stress for plants (dryness, high or low temperatures, osmotic pressure, etc.), and means of preventing aging. The present inventors have found that the above object can be achieved by providing plant activators containing, as an active ingredient, C4-C24 ketol fatty acids, in particular, 9-hydroxy-10-oxo-12(Z),15(Z)-octadecadienoic acid.
摘要翻译：本发明的目的是确定活化植物的新方法; 更具体地说，是指或控制植物生长，例如促进生长的手段，控制休眠的手段，赋予植物胁迫耐受性的手段（干燥，高温或低温，渗透压等）以及防止老化的手段。本发明人已经发现，上述目的可以通过提供含有作为有效成分的C 4 -C 24脂肪醇脂肪酸的植物活化剂来实现，特别是9 - 羟基-10-氧代-12（Z），15（Z） - 十八碳二烯酸。

120. 发明申请

US20050009808A1 Azabicyclo compound matrix metalloprotease inibitor and skin preparation 失效
标题翻译：氮杂双环化合物基质金属蛋白酶抑制剂和皮肤制剂
公开(公告)号：US20050009808A1
公开(公告)日：2005-01-13
申请号：US10495370
申请日：2002-11-13
申请人： Takuya Hiruma , Koji Kobayashi , Shinji Inomata
发明人： Takuya Hiruma , Koji Kobayashi , Shinji Inomata
IPC分类号： A61K8/49 , A61K31/403 , A61K31/439 , A61K31/4439 , A61K31/55 , A61P1/02 , A61P1/04 , A61P17/00 , A61P17/16 , A61P19/02 , A61P19/04 , A61P19/08 , A61P19/10 , A61P25/00 , A61P27/02 , A61P29/00 , A61P35/04 , A61P43/00 , A61Q19/00 , A61Q19/08 , C07D209/52 , C07D401/06 , C07D401/12 , C07D403/06 , C07D405/14 , C07D451/06 , C07D453/06 , C07D471/08 , C07D453/02 , A61K31/4745
CPC分类号： A61Q19/08 , A61K8/0212 , A61K8/492 , A61K31/403 , A61K31/439 , A61K31/4439 , A61K31/55 , A61K2800/782 , A61Q1/02 , A61Q19/00 , C07D209/52 , C07D401/06 , C07D401/12 , C07D403/06 , C07D405/14 , C07D451/06 , C07D453/06 , C07D471/08
摘要： An azabicyclo compound (I) or a salt thereof in accordance with the present invention has an excellent inhibiting action on matrix metalloproteases (MMPs) activity, and is useful for pharmaceutical, cosmetic and skin external compositions. wherein R is H, alkyl, heteroalkyl, aryl, heteroaryl, arylalkyl, heteroarylalkyl, acyl, COOR1, carbamoyl or SO2R2 (wherein R1 and R2 each are alkyl, heteroalkyl, aryl, heteroaryl, arylalkyl or heteroarylalkyl); X is methylene, ethylene or propylene; and is a single bond or a double bond.
摘要翻译：根据本发明的氮杂二环化合物（I）或其盐对基质金属蛋白酶（MMPs）活性具有优异的抑制作用，并且可用于药物，化妆品和皮肤外用组合物。其中R是H，烷基，杂烷基，芳基，杂芳基，芳基烷基，杂芳基烷基，酰基，COOR 1，氨基甲酰基或SO 2 R 2（其中R 1和R 2各自是烷基，杂烷基，芳基，杂芳基，芳基烷基或杂芳基烷基）; X是亚甲基，亚乙基或亚丙基; 并且是单键或双键。

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