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111. 发明申请

US20070282368A1 FILTER ELEMENT FOR EMBOLIC PROTECTION DEVICE 审中-公开
标题翻译：滤波器元件保护装置
公开(公告)号：US20070282368A1
公开(公告)日：2007-12-06
申请号：US11562616
申请日：2006-11-22
申请人： David Vale , Eamon Brady
发明人： David Vale , Eamon Brady
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2/01 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2250/0018 , A61F2250/0036 , A61F2250/0067
摘要： A collapsible filter element (105) for a transcatheter embolic protection device (100) comprises a collapsible filter body (30) which is movable between a collapsed stored position for movement through a vascular system and an expanded position for extension across a blood vessel such that blood passing through the blood vessel is delivered through the filter element (105). A proximal inlet portion of the filter body (30) has one or more inlet openings (117) sized to allow blood and embolic material enter the filter body (30) and a distal outlet portion of the filter body (30) has a plurality of outlet openings (119) sized to allow through-passage of blood, but to retain embolic material within the filter body (30). The filter body (30) is at least partially of laminate construction comprising a membrane (31) coated with a coating (32, 33) which is biocompatible, the thickness of the coating (32, 33) being from 4% to 40% of the thickness of the membrane (31). The coating (32, 33) man be of hydrophilic material. To facilitate retrieval of captured embolic material the distal portion and/or an intermediate portion of the filter membrane (31) may be stretchable. The filter body (30) may have regions of varying hardness or stiffness.
摘要翻译：用于经导管栓塞保护装置（100）的可折叠过滤器元件（105）包括可折叠过滤器主体（30），其可在通过血管系统移动的折叠存储位置和用于跨越血管延伸的扩展位置之间移动，使得通过血管的血液通过过滤元件（105）输送。过滤器主体（30）的近侧入口部分具有一个或多个入口开口（117），其大小允许血液和栓塞物质进入过滤器主体（30），并且过滤器本体（30）的远端出口部分具有多个出口开口（119）的尺寸允许血液通过，但是将栓塞材料保持在过滤体（30）内。过滤器主体（30）至少部分是层压结构，其包括涂覆有生物相容性的涂层（32,33）的膜（31），涂层（32,33）的厚度为4％至40％膜（31）的厚度。涂层（32,33）是亲水材料。为了便于捕获的栓塞材料的取出，过滤膜（31）的远端部分和/或中间部分可以是可拉伸的。过滤器主体（30）可以具有变化的硬度或刚度的区域。

112. 发明授权

US06964672B2 Support frame for an embolic protection device 有权
标题翻译：用于栓塞保护装置的支撑框架
公开(公告)号：US06964672B2
公开(公告)日：2005-11-15
申请号：US10326884
申请日：2002-12-23
申请人： Eamon Brady , David Vale , Ronald Kelly , John Neilan , Steven Horan , Gerard Rabitte , Gerry McCaffrey
发明人： Eamon Brady , David Vale , Ronald Kelly , John Neilan , Steven Horan , Gerard Rabitte , Gerry McCaffrey
IPC分类号： A61F2/01 , A61F29/00
CPC分类号： A61F2/01 , A61B2017/2212 , A61B2017/2215 , A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/0006 , A61F2230/0067 , A61F2230/0093
摘要： An embolic protection device comprises a collapsible filter body and a filter support for the filter body. The filter support comprises a support frame defined by at least two wire segments having terminations. The terminations of adjacent segments are fixed relative to one another and extend generally parallel in a bifilar manner for enhanced trackability and flexibility.
摘要翻译：栓塞保护装置包括可折叠过滤器主体和用于过滤器主体的过滤器支撑件。过滤器支撑件包括由具有终端的至少两个线段限定的支撑框架。相邻段的终端相对于彼此固定，并且以双向方式大致平行延伸，以增强可跟踪性和灵活性。

113. 发明申请

US20050209634A1 Support frame for an embolic protection device 审中-公开
标题翻译：用于栓塞保护装置的支撑框架
公开(公告)号：US20050209634A1
公开(公告)日：2005-09-22
申请号：US11068044
申请日：2005-03-01
申请人： Eamon Brady , David Vale , Ronald Kelly , John Neilan , Steven Horan , Gerard Rabitte , Garry McCaffrey
发明人： Eamon Brady , David Vale , Ronald Kelly , John Neilan , Steven Horan , Gerard Rabitte , Garry McCaffrey
IPC分类号： A61F2/01 , A61M29/00
CPC分类号： A61F2/01 , A61B2017/2212 , A61B2017/2215 , A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/0006 , A61F2230/0067
摘要： An embolic protection device has a support frame incorporating tethering features for connecting the support frame distally and/or proximally and/or intermediately to a carrier. Tethers may also be used additionally or alternatively for connecting various elements of a support frame. The tethers may be used to connect a support hoop 503 to a tubular member 504. The tethers provide added safety and stability to the frame without any increase in the length of the device when wrapped down for delivery.
摘要翻译：栓塞保护装置具有支撑框架，其包括用于将支撑框架向远侧和/或向近侧和/或中间连接到载体的束缚特征。系绳也可以额外地或替代地用于连接支撑框架的各种元件。系绳可以用于将支撑环503连接到管状构件504.当将包裹下来用于输送时，系绳在框架的长度方面没有任何增加，从而为框架提供附加的安全性和稳定性。

114. 发明申请

US20050027345A1 Stent delivery and deployment system 审中-公开
标题翻译：支架交付和部署系统
公开(公告)号：US20050027345A1
公开(公告)日：2005-02-03
申请号：US10779315
申请日：2004-02-17
申请人： Steven Horan , David Vale , Shane Molloy , Eamon Brady , Martin Keegan
发明人： Steven Horan , David Vale , Shane Molloy , Eamon Brady , Martin Keegan
IPC分类号： A61F2/01 , A61F2/84 , A61F2/06
CPC分类号： A61F2/966 , A61F2/013 , A61F2/95 , A61F2002/9517 , A61F2230/0006 , A61M2025/0175 , A61M2025/0675
摘要： A delivery system for delivery and deployment of a self expanding stent 1 especially in an arterial vessel with a tortuous passageway leading thereto comprises a catheter shaft 9 with a distal sheath 6. An inner core 5 is fixed to a larger diameter outer core 10, the difference in diameter providing an abutment. To deploy the stent 1, the sheath 6 is drawn proximally relative to the inner core 5, the proximal end of the stent 1 is engaged by the abutment and the stent 1 expands as it is uncovered by the sheath 6. The system includes a stabiliser tube 25 to which the inner core 5 is fixed, at least during the deployment of the stent 1.
摘要翻译：用于递送和展开自扩张支架1的递送系统，特别是在具有通向其的曲折通道的动脉血管中，包括具有远端护套6的导管轴9.内芯5固定到较大直径的外核10，提供基台的直径差异。为了部署支架1，护套6相对于内核5向近侧拉伸，支架1的近端由邻接部分接合，并且支架1由于被护套6未被覆盖而膨胀。该系统包括稳定器至少在展开支架1的过程中固定内芯5的管25。

115. 发明申请

US20070162068A1 Embolic protection system 审中-公开
标题翻译：栓塞保护系统
公开(公告)号：US20070162068A1
公开(公告)日：2007-07-12
申请号：US11512702
申请日：2006-08-30
申请人： Martin Keegan , Earnon Brady , Brendan Casey , David Vale , John Neilan , Morgan Tierney
发明人： Martin Keegan , Earnon Brady , Brendan Casey , David Vale , John Neilan , Morgan Tierney
IPC分类号： A61M29/00
CPC分类号： A61F2/0095 , A61B17/221 , A61F2/013 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2002/9522 , A61F2230/0006 , A61F2230/0067
摘要： A retrieval catheter for retrieving a medical device deployed in a vasculature. The catheter comprises an outer catheter body and an inner coupling member having means for coupling to a medical device deployed in a vasculature. The catheter body is movable distally relative to the coupling member to retrieve a coupled medical device into the catheter body.
摘要翻译：用于检索部署在脉管系统中的医疗装置的检索导管。导管包括外导管主体和具有用于联接到部署在脉管系统中的医疗装置的装置的内联接构件。导管主体可相对于联接构件向远侧移动以将耦合的医疗装置取回到导管主体中。

116. 发明申请

US20070233178A1 SUPPORT FRAME FOR AN EMBOLIC PROTECTION DEVICE 审中-公开
公开(公告)号：US20070233178A1
公开(公告)日：2007-10-04
申请号：US11762169
申请日：2007-06-13
申请人： Paul Gilson , Michael Gilvarry , Eamon Bady , David Vale , Steven Horan
发明人： Paul Gilson , Michael Gilvarry , Eamon Bady , David Vale , Steven Horan
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61F2002/018 , A61F2230/0006 , A61F2230/0067
摘要： An embolic protection device comprises a collapsible filter element for delivery through a vascular system of a patient. The filter element comprising a collapsible filter body and a filter support frame contacting the filter body. The collapsible filter body has an inlet end and an outlet end, the inlet end of the filter body having one or more inlet openings sized to allow blood and embolic material to enter the filter body, the outlet end of the filter body having a plurality of outlet openings sized to allow through passage of blood but to retain undesired embolic material within the filter body. The filter support frame is movable between a collapsed position for movement through the vascular system and an extended outwardly projecting position to support the filter body in the expanded position. The frame has a plurality of engagement segments which are spaced-apart longitudinally and transversely when the filter body is in the deployed expanded configuration to urge the filter body into opposition with the vessel wall. The engagement segments define at least partially a substantially helical engagement track.

117. 发明申请

US20090124934A1 GUIDEWIRE TORQUE DEVICE 审中-公开
标题翻译： GUIDEWIRE扭矩装置
公开(公告)号：US20090124934A1
公开(公告)日：2009-05-14
申请号：US11938028
申请日：2007-11-09
申请人： Gerard Rabbitte , David Vale
发明人： Gerard Rabbitte , David Vale
IPC分类号： A61M25/00 , A61B5/00
CPC分类号： A61M25/09041 , A61M2025/09116
摘要： In accordance with the present invention there is provided a guidewire torquing device configured to be readily attachable and detachable from a guidewire.
摘要翻译：根据本发明，提供了一种导丝扭力装置，其构造成可容易地从导丝上拆卸。

118. 发明授权

US07717936B2 Device for loading an embolic protection filter into a catheter 有权
标题翻译：用于将栓塞保护过滤器装载到导管中的装置
公开(公告)号：US07717936B2
公开(公告)日：2010-05-18
申请号：US11408732
申请日：2006-04-18
申请人： Ronan Keating , David Vale , John Neilan
发明人： Ronan Keating , David Vale , John Neilan
IPC分类号： A61M29/00
CPC分类号： A61F2/01 , A61F2002/011 , A61F2230/0006
摘要： A transvascular embolic protection system for safely capturing and retaining embolic material released during an interventional procedure comprises an embolic protection device (1) and a delivery catheter (2) for delivery of the embolic protection device (1) to a desired location in the vascular system. A pack (4) is provided to safely store and prepare the embolic protection system for use. The pack (4) comprises a tray (5) with a channel (6) extending in a looped configuration around the tray (5) for receiving the delivery catheter (2). A loading device (7) is mounted in the tray (5) adjacent to the delivery catheter (2). The embolic protection device (1) is mounted in an expanded configuration in a well (90) in the tray (5). A pushing device (8) for loading the collapsible embolic protection device (1) into the delivery catheter (2) is mounted in the tray (5) adjacent to the embolic protection device (1).
摘要翻译：一种用于安全捕获和保持在介入手术期间释放的栓塞物质的血管内栓塞保护系统，包括用于将栓塞保护装置（1）输送到血管系统中所需位置的栓塞保护装置（1）和输送导管（2）。提供一包（4）以安全地存储和准备使用的栓塞保护系统。所述包装盒（4）包括托盘（5），所述托盘（5）具有围绕所述托盘（5）以环形构造延伸的通道（6），用于接纳所述输送导管（2）。装载装置（7）安装在邻近输送导管（2）的托盘（5）中。栓塞保护装置（1）以扩展构造安装在托盘（5）中的井（90）中。用于将可折叠栓塞保护装置（1）装载到输送导管（2）中的推动装置（8）安装在邻近栓塞保护装置（1）的托盘（5）中。

119. 发明申请

US20060293705A1 Embolic protection device 有权
标题翻译：栓塞保护装置
公开(公告)号：US20060293705A1
公开(公告)日：2006-12-28
申请号：US11406822
申请日：2006-04-18
申请人： John Neilan , Ronan Keating , David Vale
发明人： John Neilan , Ronan Keating , David Vale
IPC分类号： A61M29/00
CPC分类号： A61F2/013 , A61B2017/22051 , A61B2017/22067 , A61F2002/011 , A61F2002/015 , A61F2002/018 , A61F2230/0006 , A61F2230/0067
摘要： An embolic protection device (2000) comprises a collapsible filter body (102), a filter support (103) for supporting the filter body (102), and a tubular member (108) to which the filter support (103) is mounted. The filter support (103) comprises two round wires (116). Each wire (116) has a “M”-shaped curve (120) in the wire (116) which acts as a strain distributing linking element. In an extended configuration, the concave portion of each curve (120) faces longitudinally in the distal direction. In a collapsed configuration, the concave portion faces radially inwardly towards the tubular member (108) and wraps around part of the tubular member (108) to define a compact, low-profile filter support (103). Tethers (500, 501) extend between the curves (120) and a sleeve (201) slidably mounted to the tubular member (108). The distal end of each tether (500, 501) is fixedly attached to the sleeve (201) and to the filter body (102). The sleeve (201) is slidable over the tubular member (108) between a pair of stops.
摘要翻译：栓塞保护装置（2000）包括可折叠过滤器主体（102），用于支撑过滤器本体（102）的过滤器支撑件（103）和安装过滤器支撑件（103）的管状构件（108）。过滤器支撑件（103）包括两根圆形线（116）。每根线（116）在线（116）中具有“M”形曲线（120），其作为应变分布连接元件。在延伸构造中，每个曲线（120）的凹部在远端方向上面向纵向。在折叠构造中，凹部朝向管状构件（108）径向向内，并且围绕管状构件（108）的一部分缠绕以限定紧凑的低轮廓过滤器支撑件（103）。系带（500,501）在曲线（120）和可滑动地安装到管状构件（108）的套筒（201）之间延伸。每个系绳（500,501）的远端固定地连接到套筒（201）和过滤器主体（102）上。套筒（201）可在一对止动件之间在管状构件（108）上滑动。

120. 发明申请

US20110034951A1 DEVICE FOR LOADING AN EMBOLIC PROTECTION FILTER INTO A CATHETER 审中-公开
标题翻译：用于将防爆过滤器装入导管的装置
公开(公告)号：US20110034951A1
公开(公告)日：2011-02-10
申请号：US12772463
申请日：2010-05-03
申请人： Ronan Keating , David Vale , John NEILAN
发明人： Ronan Keating , David Vale , John NEILAN
IPC分类号： A61F2/01
CPC分类号： A61F2/01 , A61F2002/011 , A61F2230/0006
摘要： A device for loading an embolic protection filter into a catheter including a loading member for collapsing an embolic protection filter, wherein an outlet of the loading member is configured to be aligned with an inlet of a catheter extending along at least part of an exterior surface of the catheter for loading of the collapsed embolic protection filter into the catheter. The loading member may have a passageway extending therethrough, through which an embolic protection filter may be passed to collapse the embolic protection filter. The outlet of the loading member may include an outlet of the passageway that is at least partially funnel-shaped. The loading member may include a tubular part extendable along part of an exterior surface of a catheter, the outlet of the loading member being provided at an end of the tubular part.
摘要翻译：一种用于将栓塞保护过滤器装载到导管中的装置，包括用于塌陷栓塞保护过滤器的装载构件，其中装载构件的出口构造成与沿着至少部分外表面延伸的导管的入口对准用于将塌陷的栓塞保护过滤器装载到导管中的导管。装载构件可以具有穿过其中的通道，栓塞保护过滤器可以通过该通道通过以使栓塞保护过滤器收缩。装载构件的出口可以包括至少部分漏斗形的通道出口。装载构件可以包括可沿着导管的外表面的一部分延伸的管状部分，装载构件的出口设置在管状部分的端部。

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