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    • 101. 发明授权
    • Atmospheric pressure ionization mass spectrometer system
    • US07081620B2
    • 2006-07-25
    • US10239063
    • 2001-11-26
    • Yoshiaki Kato
    • Yoshiaki Kato
    • H01J49/04
    • H01J49/0404H01J49/045
    • In order to provide an atmospheric pressure ionization mass spectrometer system which allows for equal high sensitivity analysis for LCs with different flow rates, there is provided an atmospheric pressure ionization mass spectrometer system comprising: an atmospheric pressure ion source for ionizing a sample solution under atmospheric pressure, a mass spectrometer for mass analyzing the ions in an evacuated space, a fine hollow tube on a partition wall between the atmospheric pressure ion source and the mass spectrometer, the ions generated in the atmospheric pressure ion source being introduced through the fine tube into the mass spectrometer to be mass analyzed, wherein the fine tube consists of a first fine tube and a second fine tube which are different in diameter, the second fine tube being inserted in the first fine tube, the ions and gas generated in the atmospheric pressure ion source are introduced into the mass spectrometer through the second fine tube, and a gas is fed into a space between the first fine tube and the second fine tube. The present invention allows for high sensitivity measurements of mass spectrometer systems including the micro LC, CE, and nanospray with very low flow rate and the conventional LC with much higher flow rate. In addition, the clogged fine tube can be exchanged without stopping the vacuum pumping, providing the simplified maintenance.
    • 106. 发明授权
    • Electrospray ionization mass analysis apparatus and system thereof
    • 电喷雾电离质量分析装置及其系统
    • US06809316B2
    • 2004-10-26
    • US10221844
    • 2003-02-11
    • Yoshiaki Kato
    • Yoshiaki Kato
    • B01D5944
    • H01J49/0031H01J49/0431H01J49/165
    • Because of a low flow rate of the micro LC/MS, the dead volume or the diameter of a capillary tube must be minimized, and a sample and salt are likely to deposit in the capillary tube, with the result that clogging of the capillary tube and ESI nozzle often occurs. An electrospray ionization mass analysis apparatus and its system of the present invention predicts clogging, permit earlier cleaning or parts replacement, and detect clogging even if it has occurred, thereby suspending measurement and preventing samples from being introduced into an injector, with the result that waste of samples is avoided and effective data is ensured. The aforementioned electrospray ionization mass analysis apparatus directly coupled to the micro LC prevents a micro LC, piping and ESI capillary tube from being clogged, and records an alarm in the data and stops the system whenever clogging has occurred, whereby highly reliable direct coupling with micro LC is ensured. In the aforementioned electrospray ionization mass analysis apparatus and its system, a sample solution from a chromatograph is introduced into a capillary tube, and an electrospray ion source arranged for generating ions under atmospheric pressure generates ions, which are led into a mass spectrometer disposed in a vacuum chamber where the ion is subjected to mass analysis. The current value or strength of the ion having a specified mass in the sample solution is measured, and, when the current value has reduced below a threshold value, an error state is displayed.
    • 107. 发明授权
    • Switchable connector device
    • 可切换连接器装置
    • US06773283B2
    • 2004-08-10
    • US09858906
    • 2001-05-17
    • Kazuharu YoshimatsuYoshiaki KatoKeiichi ItoKazuyuki ShirakiMasanori Wakui
    • Kazuharu YoshimatsuYoshiaki KatoKeiichi ItoKazuyuki ShirakiMasanori Wakui
    • H01R1362
    • H01R12/714H01R12/515H01R12/7047H01R13/24
    • A connector housing (6) of the connector device (1) is composed of an outer housing (9) to be mounted onto a printed circuit board (2) by screwing, and an inner housing (8) connected to the outer housing (9) so as to be movable in the right and left direction with respect to the outer housing (9). Into the inner housing (8), there is incorporated a terminal (7) including a connecting portion (7a) to be connected by a terminal (5) of a mating connector device (3), a spring portion (7c), and a switch contact (7b) respectively formed integral with the terminal (7). On the printed circuit board (2), there is disposed an electrode (2a) with which the switch contact (7b) can be elastically contacted. Thanks to this structure, by switchingly moving the inner housing (8) in the right and left direction, circuit switching can be achieved.
    • 连接器装置(1)的连接器壳体(6)由通过旋拧安装在印刷电路板(2)上的外壳体(9)和连接到外壳体(9)的内壳体 )相对于外壳体(9)在左右方向上移动。 在内壳体(8)内装有一个端子(7),该端子(7)包括一个连接部分(7a),该连接部分通过配合的连接器装置(3)的端子(5),一个弹簧部分(7c)和 分别与端子(7)形成的开关触点(7b)。 在印刷电路板(2)上设置有电极(2a),开关触点(7b)可与该电极弹性接触。 由于这种结构,通过在左右方向上切换内部壳体(8),能够实现电路切换。
    • 108. 发明授权
    • Electrospray ionization mass analysis apparatus and method thereof
    • 电喷雾电离质量分析装置及其方法
    • US06737640B2
    • 2004-05-18
    • US10221845
    • 2002-09-16
    • Yoshiaki Kato
    • Yoshiaki Kato
    • H01J2700
    • H01J49/165G01N27/62G01N30/7266Y10T436/24
    • The object of the present invention is to provide an electrospray ionization mass analysis apparatus and the method thereof provided with an ESI ion source that can be directly coupled to a micro LC. The present invention provides an electrospray ionization mass analysis apparatus characterized in that a sample solution is led into a capillary tube, and high voltage is applied to the tip of this capillary tube, thereby allowing a spray ion flow of the aforementioned solution to be generated by an electrospray ion source provided therein. The ion flow generated by this ion source is led to an ion storage type spectrometer disposed in an vacuum chamber where it is subjected to mass sweeping, and the swept ion is detected by a detector so that a mass spectrum is obtained. This electrospray ionization mass analysis apparatus is further characterized by comprising a high voltage DC power source for application of the aforementioned high voltage formed by AC voltage superimposed on the DC voltage, and a AC power source. This invention ensures stable and highly sensitive ESI ionization to be performed at a flow rate ranging from several 10 &mgr;L/min to several &mgr;L/min.
    • 本发明的目的是提供一种电喷雾离子化质量分析装置及其提供有可直接耦合到微LC的ESI离子源的方法。本发明提供一种电喷雾离子质量分析装置,其特征在于, 溶液被引入毛细管中,并且高压施加到毛细管的尖端,从而允许由其中提供的电喷雾离子源产生上述溶液的喷雾离子流。 由该离子源产生的离子流被导入设置在真空室中的离子存储型光谱仪,在其中进行质量扫描,并且通过检测器检测扫描离子,从而获得质谱。 该电喷雾离子化质量分析装置的特征还在于,包括用于施加由叠加在直流电压上的交流电压形成的上述高电压的高压直流电源和交流电源。本发明确保了稳定且高灵敏度的ESI电离 以几10L / min至几μL/ min的流速进行。
    • 109. 发明授权
    • Controller for automatic transmissions
    • 自动变速箱控制器
    • US06736755B2
    • 2004-05-18
    • US10130309
    • 2002-05-16
    • Yoshiaki Kato
    • Yoshiaki Kato
    • B60K4120
    • F16H61/0021B60W10/06B60W10/115B60W30/18018F16H59/54F16H61/0206F16H61/20F16H63/50F16H2061/0477F16H2200/0047F16H2200/201F16H2312/02F16H2312/14Y10T477/644Y10T477/6895
    • There are arranged an engine 10 having idle-stop control means and an automatic transmission 20 having as a hydraulic-pressure supply source a main pump 22 driven by the engine 10 to perform speed change control. There are arranged a bypass hydraulic passage 45 for ensuring communication between said main pump 22 and a point immediately before an engagement-pressure supply port of a forward engagement element L/C in the automatic transmission, a switching valve 44 on the bypass hydraulic passage 45 for allowing switching between the communicating state and the non-communicating state, and switching-valve control means for switching the switching valve 44 between the communicating state and the non-communicating state. With this, the main pump is stopped at idle-stop control to supply the hydraulic pressure required for restart, allowing smooth running.
    • 具有怠速停止控制装置的发动机10和具有由发动机10驱动的主泵22作为液压供给源的自动变速器20进行变速控制。 设置有用于确保主泵22与紧接在自动变速器中的前进接合元件L / C的接合压力供给口之间的点之间的连通的旁通液压通道45,旁通液压通道45上的切换阀44 用于允许在通信状态和非通信状态之间切换;以及切换阀控制装置,用于在通信状态和非通信状态之间切换切换阀44。 这样,主泵在怠速停止控制下停止供给重新启动所需的液压,允许平稳运行。