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91. 发明专利

JPH01113362A BIS-OXYETHYLSULFONYLMETHYL-ANILINE AND ITS PRODUCTION 失效
公开(公告)号：JPH01113362A
公开(公告)日：1989-05-02
申请号：JP24265088
申请日：1988-09-29
申请人： HOECHST AG
发明人： TEODOORU PAPENFUUSU , YOOZEFU GAIZENBERUGERU
IPC分类号： C07C323/29 , B01J23/30 , C07B61/00 , C07C67/00 , C07C313/00 , C07C315/00 , C07C315/02 , C07C317/04 , C07C317/26 , C07C317/28 , C07C317/36 , C07C321/12

92. 发明专利

JPS60258157A TRISULFIDE COMPOUND AND ITS PREPARATION 失效
公开(公告)号：JPS60258157A
公开(公告)日：1985-12-20
申请号：JP11325884
申请日：1984-06-02
申请人： RIKEN CHEMICAL IND , KOMINATO YUKIKO , KOMINATO RIEKO
发明人： KOMINATO JIYOU
IPC分类号： A23L27/20 , A23F5/46 , A23L27/10 , A61K31/10 , A61K31/19 , A61K31/22 , A61K31/34 , A61K31/341 , A61P7/02 , A61P9/00 , C07C67/00 , C07C313/00 , C07C319/14 , C07C319/22 , C07C319/24 , C07C321/12 , C07C321/14 , C07C321/16 , C07C321/18 , C07C321/20 , C07C321/22 , C07C321/24 , C07C321/28 , C07C323/12 , C07C323/52 , C07D307/10 , C07D307/33 , C07D307/38
摘要： NEW MATERIAL:The compound of formula (R1 and R2 are 1-12C cyclic or acyclic alkyl or alkenyl which may contain ether, carboxyl, ketone, phenyl, etc.). EXAMPLE:Ethyl aryl trisulfide. USE:Useful as perfume, antithrombotic agent, agricultural fungicide, etc. It has strong thrombocyte-coagulation suppressing activity, and is useful for the prevention and remedy of various blood vessel diseases. PREPARATION:The compond of formula I can be prepared by reacting 1mol of a hydrodisulfide with >=1/2mol of a thiol sulfide or >=1mol of a thiol sulfonate or >=1mol of an alkyl thiol or aryl thioisourea derivative in an inert solvent.

93. 发明授权

US10435362B2 Process for oxidizing one or more thiol compounds and subsequent separation in a single vessel 有权
公开(公告)号：US10435362B2
公开(公告)日：2019-10-08
申请号：US15808609
申请日：2017-11-09
申请人： UOP LLC
发明人： Jonathan A. Tertel , Susanna K. Wong
IPC分类号： C07C319/14 , C07C321/12 , B01D11/04 , B01D11/00
摘要： One exemplary embodiment can be a process for oxidizing one or more thiol compounds from an alkaline stream. The process may include passing a mixed stream having the alkaline stream to a vessel having an oxidation section, a separation section and a vent gas section. Often, the oxidation section includes a body containing one or more packing elements. The process can further include passing an oxidized alkaline stream to the separation section containing a first chamber and a second chamber. Usually, the first chamber contains a coated mesh and packing. The two sections further form a neck contains a packing, a distributor, and a mesh.

94. 发明申请

US20180170864A1 PROCESS FOR OXIDIZING ONE OR MORE THIOL COMPOUNDS AND SUBSEQUENT SEPARATION IN A SINGLE VESSEL 审中-公开
公开(公告)号：US20180170864A1
公开(公告)日：2018-06-21
申请号：US15808609
申请日：2017-11-09
申请人： UOP LLC
发明人： Jonathan A. Tertel , Susanna K. Wong
IPC分类号： C07C319/14 , C07C321/12 , C07C321/02 , C07C321/24 , B01D11/04
CPC分类号： C07C319/14 , B01D11/0484 , B01D11/0488 , B01D11/0492 , B01D2011/002 , C10G2300/202 , C10G2300/207 , C07C321/12
摘要： One exemplary embodiment can be a process for oxidizing one or more thiol compounds from an alkaline stream. The process may include passing a mixed stream having the alkaline stream to a vessel having an oxidation section, a separation section and a vent gas section. Often, the oxidation section includes a body containing one or more packing elements. The process can further include passing an oxidized alkaline stream to the separation section containing a first chamber and a second chamber. Usually, the first chamber contains a coated mesh and packing. The two sections further form a neck contains a packing, a distributor, and a mesh.

95. 发明授权

US08309710B2 Use of N-alkyl imidazole for sulfurization of oligonucleotides with an acetyl disulfide 有权
标题翻译：使用N-烷基咪唑用乙酰基二硫化物硫化寡核苷酸
公开(公告)号：US08309710B2
公开(公告)日：2012-11-13
申请号：US12494118
申请日：2009-06-29
申请人： Agnieszka B. Sierzchala , Douglas J Dellinger , Paul A. Metz , Victor R Mokler
发明人： Agnieszka B. Sierzchala , Douglas J Dellinger , Paul A. Metz , Victor R Mokler
IPC分类号： C07H1/00 , C07H21/00 , C07D233/58 , C07C321/12
CPC分类号： C07H21/02
摘要： A method and compositions for sulfurizing at least one phosphite or thiophosphite linkage in an oligonucleotide. The addition of N-alkyl imidazole to the acetyldisulfide sulfurization solution enables the use of industrially preferred solvents or solvents that are derived from renewable resources.
摘要翻译：一种在寡核苷酸中硫化至少一种亚磷酸酯或硫代亚磷酸酯键的方法和组合物。向乙酰二硫化硫化溶液中加入N-烷基咪唑可以使用衍生自可再生资源的工业上优选的溶剂或溶剂。

96. 发明授权

US07648843B2 Field of modular multifunctional ligands 有权
标题翻译：模块化多功能配体领域
公开(公告)号：US07648843B2
公开(公告)日：2010-01-19
申请号：US11775255
申请日：2007-07-10
申请人： Harry Tetsuo Uyeda , Hedi M Mattoussi , Igor L Medintz
发明人： Harry Tetsuo Uyeda , Hedi M Mattoussi , Igor L Medintz
IPC分类号： G01N33/543 , G01N33/551 , G01N33/544 , C07C321/12 , C07C321/16
CPC分类号： B82Y15/00 , B82Y5/00 , B82Y10/00 , G01N33/532 , G01N33/588 , Y10T436/182
摘要： This invention pertains to a surface ligand; preparation of the ligand; colloidal nanoparticle, such as quantum dot bearing one or more of the ligand; and a bioconjugate characterized by a nanoparticle bearing one or more of the ligand conjugated to a biomolecule. The ligand is characterized by the presence of a first module containing atoms that can attach to an inorganic surface; a second module that imparts water-solubility to the ligand and to the inorganic surface that may be attached to the ligand; and a third module that contains a functional group that can, directly or indirectly, conjugate to a biomolecule. Order of the modules can be different and other modules and groups can be on the ligand. Preparation of the ligand includes the steps of reacting a compound having atoms that can attach to an inorganic surface with a water-solubilizing compound that imparts the property of water-solubility to the ligand and the inorganic surface to which it may be attached and purification thereof. Colloidal nanoparticle is characterized by an inorganic surface having attached to it one or more of the ligands. The colloidal bioconjugate is characterized by an inorganic surface having attached thereto one or more of the ligand wherein at least some of the ligand have a biomolecule conjugated thereto.
摘要翻译：本发明涉及表面配体; 配体的制备; 胶体纳米颗粒，例如带有一个或多个配体的量子点; 其特征在于具有一个或多个与生物分子缀合的配体的纳米颗粒。该配体的特征在于存在可以附着到无机表面上的原子的第一模块; 赋予配体和附着于配体的无机表面的水溶性的第二模块; 以及包含可以直接或间接缀合到生物分子的官能团的第三模块。模块的顺序可以不同，其他模块和组可以在配体上。配体的制备包括以下步骤：将具有可附着于无机表面的原子的化合物与赋予其可配位的无机表面和赋予其水溶性的水溶性化合物反应。胶体纳米颗粒的特征在于其上连接有一个或多个配体的无机表面。胶体生物缀合物的特征在于其上附着有一种或多种配体的无机表面，其中至少一些配体具有与其缀合的生物分子。

97. 发明授权

US07012159B1 Phenolic compounds and recording materials containing the same 有权
标题翻译：酚类化合物和含有相同的记录材料
公开(公告)号：US07012159B1
公开(公告)日：2006-03-14
申请号：US10089131
申请日：2000-10-04
申请人： Tomoya Hidaka , Shinichi Sato , Tadashi Kawakami
发明人： Tomoya Hidaka , Shinichi Sato , Tadashi Kawakami
IPC分类号： C07C233/05 , C07C321/12 , C07C317/02
CPC分类号： B41M5/3336 , B41M5/155 , C07C317/24 , C07C317/44 , C07C323/22 , C07C323/60
摘要： Phenolic compounds of general formula (I); and recording materials characterized by containing one of them and exhibiting high light stability wherein R1 and R2 are each hydrogen or C1-C6 alkyl; m is an integer of 1 to 6; n is an integer of 0 to 2; p and t are each an integer of 0 to 3 with the proviso that not both are simultaneously 0; R3 and R4 are each nitro, carboxyl, halogeno, C1-C6 alkyl, or the like; q and u are each an integer of 0 to 2 with the proviso that when q or u is 2, R3s or R4s may be different from each other; and Y is CO or NR5CO (wherein R5 is hydrogen or the like), with the proviso that when Y is CO, p is 1 and that when p is 0 and Y is NR5CO, n is not 0.
摘要翻译：通式（I）的酚类化合物; 以及其中含有其中一种并表现出高光稳定性的记录材料，其中R 1和R 2各自为氢或C 1 -C 3烷基，烷基; m为1〜6的整数。 n为0〜2的整数， p和t各自为0至3的整数，条件是两者不同时为0; R 3和R 4各自为硝基，羧基，卤代C 1 -C 6烷基，或者喜欢; q和u各自为0至2的整数，条件是当q或u为2时，R 3或R 4可以彼此不同; 并且Y是CO或NR 5 CO（其中R 5是氢等），条件是当Y是CO时，p是1，当p是 0和Y是NR 5 CO，n不为0。

98. 发明申请

US20040110992A1 Method for making bisphenol a 有权
标题翻译：制备双酚A的方法
公开(公告)号：US20040110992A1
公开(公告)日：2004-06-10
申请号：US10466814
申请日：2003-12-19
发明人： Annie Commarieu
IPC分类号： C07C039/16 , C07C321/12
CPC分类号： C07C37/20 , C07C39/16
摘要： The continuous process for manufacturing bisphenol A according to the invention, by reacting phenol and acetone in the presence of a strong acid catalyst and a co-catalyst, is carried out using as co-catalyst a dithio ether of general formula: 1 in which the symbols R and Rnull each represent a hydrogen atom, an alkyl radical or a phenyl radical, and the symbol Rnull represents an optionally substituted alkyl radical.
摘要翻译：通过使苯酚和丙酮在强酸催化剂和助催化剂存在下反应制备本发明的双酚A的连续方法使用通式如下的二硫醚作为助催化剂进行：其中符号 R和R'各自表示氢原子，烷基或苯基，符号R“表示任选取代的烷基。

99. 发明授权

US6051739A Process for producing organic polysulfides 失效
标题翻译：生产有机多硫化物的方法
公开(公告)号：US6051739A
公开(公告)日：2000-04-18
申请号：US236976
申请日：1999-01-26
申请人： James E. Shaw
发明人： James E. Shaw
IPC分类号： C07B61/00 , C07C319/24 , C07C319/26 , C07C321/04 , C07C321/14 , C07C321/12 , C07C319/22
CPC分类号： C07C319/24
摘要： A process for producing an organic polysulfide compound comprises contacting, in the presence of a catalyst, a mercaptan with elemental sulfur to produce a product medium and contacting the product medium with a material comprising carbon dioxide or a carbon dioxide-generating compound wherein the catalyst comprises a base and optionally a surfactant and the organic polysulfide contains about 3 or more sulfur atoms per molecule.
摘要翻译：制备有机多硫化合物的方法包括在催化剂存在下硫醇与元素硫接触以产生产物介质，并使产物介质与包含二氧化碳或二氧化碳生成化合物的材料接触，其中催化剂包含碱和任选的表面活性剂，有机多硫化物每分子含有约3个或更多个硫原子。

100. 发明授权

US6018068A Naphthyloxyacetic acid derivatives and drugs comprising the same as active ingredients 失效
标题翻译：萘氧基乙酸衍生物和包含与活性成分相同的药物
公开(公告)号：US6018068A
公开(公告)日：2000-01-25
申请号：US102
申请日：1998-01-26
申请人： Yuuki Nagao , Kazuhiko Torisu , Nobuyuki Hamanaka
发明人： Yuuki Nagao , Kazuhiko Torisu , Nobuyuki Hamanaka
IPC分类号： C07C59/68 , C07C69/712 , C07C217/60 , C07C233/18 , C07C255/16 , C07C317/18 , C07C323/16 , C07D257/04 , C07C321/12 , C07C317/00
CPC分类号： C07D257/04 , C07C217/60 , C07C233/18 , C07C255/16 , C07C317/18 , C07C323/16 , C07C59/68 , C07C69/712
摘要： The naphthyloxyacetic acid derivatives of the formula (I) ##STR1## wherein A is H, --(alkylene)COOR.sup.1, --(alkylene)CONR.sup.2 R.sup., --(alkylene)OH, --(alkylene)tetrazole, --(alkylene)CN; E is single bond or alkylene; G is --S--, --SO--, --SO.sub.2 --, --O-- or --NR.sup.4 --; L is alkylene, --(CH.sub.2).sub.m --CH=CH--(CH.sub.2).sub.n -- or --(CH.sub.2).sub.x --CH(OH)--(CH.sub.2).sub.y --; M is phenyl, phenyl(thio, oxy, amino), diphenylmethyl, diphenylmethyl(thio, oxy, amino), and pharmaceutical composition comprising them as an active ingradient. The compounds of the formula (I) can combine PGE.sub.2 receptor and exhibit the activity to antagonize or agonize for PGE.sub.2 receptor. Therefore, they are useful as anti-hyperlipemia, for the prevention of abortion, for analgesics, as antidiarrheals, sleep inducer, diuretic, anti-diabetes, abortient, cathartics, antiulcer, anti-gastritis or antihypertensive etc.
摘要翻译： PCT No.PCT / JP96 / 01833 Sec。 371日期1998年1月26日 102（e）日期1998年1月26日PCT提交1996年7月2日PCT公布。公开号WO97 / 05091 日本时间1997年2月13日其中A为H， - （亚烷基）COOR1 - （亚烷基）CONR2R， - （亚烷基）OH， - （亚烷基）四唑， - （亚烷基）CN的式（I）的萘氧基乙酸衍生物 E是单键或亚烷基; G是-S - ， - SO - ， - SO 2 - ， - O-或-NR 4 - ; L是亚烷基， - （CH 2）m -CH = CH-（CH 2）n - 或 - （CH 2）x -CH（OH） - （CH 2）y - M是苯基，苯基（硫代，氧基，氨基），二苯基甲基，二苯基甲基（硫代，氧基，氨基），以及包含它们作为活性成分的药物组合物。式（I）化合物可以组合PGE 2受体并表现出拮抗或激动PGE2受体的活性。因此，它们可用作抗高血脂，防止流产，镇痛药，止泻药，睡眠诱导剂，利尿剂，抗糖尿病，止痛药，通气药，抗溃疡药，抗胃炎或抗高血压药等。

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