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91. 发明授权

US5061401A Electrically conductive composition of polyheteroaromatic compounds and polymeric sulfates 失效
标题翻译：聚异氰酸酯化合物和聚合硫酸酯的电导电组合物
公开(公告)号：US5061401A
公开(公告)日：1991-10-29
申请号：US401352
申请日：1989-08-31
申请人： Wolfgang Wernet , Jean Stoffer
发明人： Wolfgang Wernet , Jean Stoffer
IPC分类号： C08L29/00 , C08G61/12 , C08L27/12 , C08L29/04 , C08L33/04 , C08L33/10 , C08L65/00 , C08L67/00 , C08L79/00 , C08L101/00 , H01B1/12 , H01M4/60
CPC分类号： H01M4/60 , C08G61/123 , C08L65/00 , H01B1/127 , H01B1/128 , C08L101/00
摘要： A composition comprising (a) at least one oxidized polycationic polyheteroaromatic compound and (b) at least one polyanion of a film-forming thermoplastic polymer containing sulfated alcohol groups ##STR1## in repeating structural units. The composition has high electrical conductivity and good mechanical properties, especially after drawing at temperatures below the melt/decomposition temperature. The material may be used as electrodes, electrically conductive filaments or components for electromagnetic screening.
摘要翻译：一种组合物，其包含（a）至少一种氧化聚阳离子聚异氰脲酸酯化合物和（b）至少一种含有重复结构单元的硫酸化醇基团的成膜热塑性聚合物的聚阴离子。该组合物具有高导电性和良好的机械性能，特别是在低于熔体/分解温度的温度下拉伸后。该材料可以用作电极，导电丝或用于电磁屏蔽的部件。

92. 发明申请

US20110207788A1 5-Ring Heteroaromatic compounds and their use as binding partners for 5-ht5 receptors 有权
标题翻译： 5环杂芳族化合物及其作为5-ht5受体的结合伴侣的用途
公开(公告)号：US20110207788A1
公开(公告)日：2011-08-25
申请号：US11990731
申请日：2006-08-21
申请人： Wilhelm Amberg , Astrid Netz , Andreas Kling , Michael Ochse , Udo Lange , Andreas Haupt , Francisco Javier Garcia-Ladona , Wolfgang Wernet , Alfred Hahn
发明人： Wilhelm Amberg , Astrid Netz , Andreas Kling , Michael Ochse , Udo Lange , Andreas Haupt , Francisco Javier Garcia-Ladona , Wolfgang Wernet , Alfred Hahn
IPC分类号： A61K31/42 , C07D233/00 , C07D249/14 , C07D261/06 , A61K31/415 , A61K31/4196 , A61P25/28
CPC分类号： C07D417/04 , C07D231/38 , C07D233/70 , C07D233/88 , C07D249/14 , C07D405/04 , C07D409/04 , C07D413/04
摘要： The invention relates to 5-ring heteroaromatic compounds of general formula (I), their use for the treatment and/or prevention of diseases, and medicaments containing same.
摘要翻译：本发明涉及通式（I）的5-环杂芳族化合物，其用于治疗和/或预防疾病的用途，以及含有它们的药物。

93. 发明授权

US5338863A Process for the preparation of tetrathiotetracenes 失效
标题翻译：四硫代四烯的制备方法
公开(公告)号：US5338863A
公开(公告)日：1994-08-16
申请号：US3067
申请日：1993-01-11
申请人： Marcus Baumann , Carl W. Mayer , Wolfgang Wernet , Walter Fischer
发明人： Marcus Baumann , Carl W. Mayer , Wolfgang Wernet , Walter Fischer
IPC分类号： B05D1/20 , C07C69/00 , C07C69/16 , C07C69/18 , C07C69/732 , C07C69/94 , C07C255/13 , C07C255/15 , C07C255/46 , C07C317/22 , C07C323/21 , C07D495/06 , C07F7/08 , C08G61/12 , C09K9/02 , H01B1/12
CPC分类号： C07D495/06 , B05D1/202 , B82Y30/00 , B82Y40/00 , C07C317/22 , C07C323/21 , C07C69/00 , C07F7/0818 , C08G61/123 , H01B1/121 , C07C2103/00 , C07C2103/44
摘要： Compounds of the formula I ##STR1## in which R.sup.1 to R.sup.8 independently of one another are H and at least one of R.sup.1 and R.sup.8 is a substituent belonging to the group --F, --Si(C.sub.1 -C.sub.4 alkyl).sub.3 or --COOR.sup.10 ; or each pair of adjacent radicals of R.sup.1 to R.sup.8 is --CO--O--CO--; or at least one of R.sup.1 to R.sup.8 is C.sub.1 -C.sub.20 alkyl-(X).sub.p --, C.sub.2 -C.sub.20 alkenyl-(X).sub.p --, C.sub.2 -C.sub.20 -alkynyl-(X).sub.p --, C.sub.3 -C.sub.8 cycloalkyl-(X).sub.p --, (C.sub.1 -C.sub.12 alkyl-C.sub.3 -C.sub.8 cycloalkyl-(X).sub.p --, C.sub.3 -C.sub.8 -cycloalkyl-CH.sub.2 --(X).sub.p --, C.sub.1 -C.sub.12 alkyl-C.sub.3 -C.sub.8 cycloalkyl-CH.sub.2 --(X).sub.p --, C.sub.6 -C.sub.10 aryl-X--, C.sub.7 -C.sub.20 alkaryl-X--, C.sub.7 -C.sub.12 aralkyl-(X).sub.p -- or C.sub.8 -C.sub.20 -alkaralkyl-(X).sub.p -- or --Y-- (C.sub.m H.sub.2m --O)--.sub.n R.sup.10 each of which is unsubstituted or substituted by --F, --OH, --CN, C.sub.1 -C.sub.12 alkoxy, C.sub.1 -C.sub.12 acyloxy or --COOR.sup.10 ; R.sup.10 is H or C.sub.1 -C.sub.18 alkyl, X is --O--, --S--, --SO-- or --SO.sub.2 -- and Y is --O-- or --S--, and p is 0 or 1, m is a number from 2 to 6 and n is a number from 2 to 20; and R.sup.9 is C.sub.1 -C.sub.4 acyl which is unsubstituted or substituted by --F.The compounds of the formula I can be reacted directly with sulfur in the presence of catalytic amounts of a sulfonic acid to give 5,6,11,12-tetrathiotetracenes which form electrically conducting charge-transfer complexes with electron donors.
摘要翻译：其中R 1至R 8彼此独立地为H并且R 1和R 8中的至少一个为属于基团-F，-Si（C 1 -C 4烷基）3或 - COOR10; 或R 1至R 8的每对相邻基团是-CO-O-CO-; 或者R 1至R 8中的至少一个为C 1 -C 20烷基 - （X）对，C 2 -C 20烯基 - （X）对，C 2 -C 20炔基 - （X）对 - ，C 3 -C 8环烷基 - （X），（C 1 -C 12烷基-C 3 -C 8环烷基 - （X）对 - ，C 3 -C 8 - 环烷基-CH 2 - （X）对，C 1 -C 12烷基-C 3 -C 8环烷基-CH 2 - （X） X，C7-C20烷芳基 - （X）对或C8-C20-烷基烷基 - （X）对 - 或-Y-（CmH2m-O）-n10，其各自未被取代或被 -F，-OH，-CN，C 1 -C 12烷氧基，C 1 -C 12酰氧基或-COOR 10; R 10是H或C 1 -C 18烷基，X是-O - ， - S - ， - SO-或-SO 2 - ，Y是-O - 或-S-，p为0或1，m为2至6的数，n为2至20的数; R 9为未被取代或被-F取代的C 1 -C 4酰基，在催化量的磺酸存在下，式I可以直接与硫反应，得到5,6,11,12-四硫代四烯，其与电子给体形成导电电荷转移络合物。

94. 发明授权

US5206297A Electrically conductive moulding compositions and fillers from polyheteroaromatic compounds and polymeric sulfates 失效
标题翻译：来自聚异氰酸酯化合物和聚合硫酸酯的电导电成型组合物和填料
公开(公告)号：US5206297A
公开(公告)日：1993-04-27
申请号：US665494
申请日：1991-03-06
申请人： Wolfgang Wernet , Friedrich Lohse , Jurgen Finter , Hartmut Bleier , Bruno Rotzinger , Thomas Vogel
发明人： Wolfgang Wernet , Friedrich Lohse , Jurgen Finter , Hartmut Bleier , Bruno Rotzinger , Thomas Vogel
IPC分类号： C08L79/08 , C08G59/14 , C08G61/12 , C08G65/48 , C08L81/06 , C08L101/00 , C08L101/02 , H01B1/12
CPC分类号： H01B1/128 , C08G59/1411 , C08G61/123 , C08G65/48 , C08L81/06 , H01B1/127
摘要： Moulding composition in the form of particles of a) at least one polyheteroaromatic compound or an aniline in the oxidised, polycationic form, especially polypyrrole, and b) at least one polyanion of a thermoplastic polymer having sulfated alcohol groups ##STR1## in recurring structural units. Mouldings obtained from the moulding compositions have a high electrical conductivity and good mechanical strength properties. The mouldings can be used as electrodes, electrically conductive fibers or components for electromagnetic screening. The pulverulent moulding compounds are also suitable as electrically conductive fillers for plastics.
摘要翻译： a）至少一种氧化的聚阳离子形式的聚异氰脲酸化合物或苯胺，特别是聚吡咯的颗粒形式的成型组合物，和b）具有重复结构单元中具有硫酸化醇基团的热塑性聚合物的至少一种聚阴离子。从成型组合物得到的模制品具有高导电性和良好的机械强度性能。模制品可以用作电极，导电纤维或用于电磁屏蔽的部件。粉状模塑料也适用于塑料用导电填料。

95. 发明授权

US5158829A Electroactive ultra-thin layers 失效
标题翻译：电活动超薄层
公开(公告)号：US5158829A
公开(公告)日：1992-10-27
申请号：US753506
申请日：1991-09-03
申请人： Alex Wegmann , Bernd Tieke , Carl W. Mayer , Bruno Hilti , Walter Fischer , Wolfgang Wernet
发明人： Alex Wegmann , Bernd Tieke , Carl W. Mayer , Bruno Hilti , Walter Fischer , Wolfgang Wernet
IPC分类号： C07D495/06 , B05D1/20 , C07D517/06 , C08G61/12 , C08J5/18 , C09K3/00 , H01B1/12
CPC分类号： B05D1/202 , B82Y30/00 , B82Y40/00 , C08G61/123 , H01B1/121 , Y10T428/31504
摘要： Monolayer or multilayer systems containing compounds of the formula I ##STR1## in which X is S or Se, R.sup.1 is C.sub.1 -C.sub.30 alkyl, --CF.sub.3, --O--R.sup.3, --S--R.sup.3 or --CO--O--R.sup.3, R.sup.2 is hydrogen, C.sub.1 -C.sub.30 alkyl, --CF.sub.3, --O--R.sup.3, --S--R.sup.3 or --CO--O--R.sup.3, and R.sup.3 is C.sub.1 -C.sub.30 alkyl or partially or perfluorinated C.sub.1 -C.sub.30 alkyl, are described.Electrically conductive layers which are suitable, for example, for the production of electrically conductive coatings can be prepared from the layer systems by doping with electron acceptors.
摘要翻译：含有式I的化合物（I）的单层或多层体系，其中X为S或Se，R1为C1-C30烷基，-CF3，-O-R3，-S-R3或-CO-O-R3， R 2是氢，C 1 -C 30烷基，-CF 3，-O-R 3，-S-R 3或-CO-O-R 3，R 3是C 1 -C 30烷基或部分或全氟化的C 1 -C 30烷基。可以通过掺杂电子受体从层系统制备适合于例如用于制备导电涂层的导电层。

96. 发明申请

US20120027998A1 SURFACE RELIEF MICROSTRUCTURES, RELATED DEVICES AND METHOD OF MAKING THEM 有权
标题翻译：表面消除微结构，相关设备及其制造方法
公开(公告)号：US20120027998A1
公开(公告)日：2012-02-02
申请号：US13148849
申请日：2010-02-15
申请人： Mohammed Ibn-Elhaj , Julien Martz , Hubert Seiberle , Wolfgang Wernet
发明人： Mohammed Ibn-Elhaj , Julien Martz , Hubert Seiberle , Wolfgang Wernet
IPC分类号： G02B5/00 , B29C59/02 , B32B3/00 , C23F1/02
CPC分类号： G03F7/0002 , B82Y40/00 , C25D1/00 , C25D1/10 , G02B5/0221 , G02B5/0257 , G02B5/0268 , G02B5/1847 , G02B5/1857 , G02F1/13378 , G03F7/0017 , G11B7/261 , Y10T428/24479 , Y10T428/24521
摘要： The present invention relates to a method for the replication of a patterned surface relief microstructure, comprising the steps of generation of a first layer with a patterned surface relief microstructure, generation of a master, by copying the microstructure of the first layer into a second layer, thereby involving at least one dry or wet etching step, characterized by an additional step, in which the microstructure of the master is brought into contact with a replica material, such that the microstructure of the master is reproduced in the replica.The invention further relates to the elements made as a replica according to the method.The surface relief microstructures are suitable to display images with a positive-negative and/or color image flip. The elements according to the invention are particularly useful for securing documents and articles against counterfeiting and falsification.
摘要翻译：本发明涉及一种用于复制图案化表面浮雕微结构的方法，包括以下步骤：通过将第一层的微结构复制到第二层中来产生具有图案化表面浮雕微结构的第一层，生成母版，从而涉及至少一个干蚀刻或湿蚀刻步骤，其特征在于附加步骤，其中使母版的微结构与复制材料接触，使得主体的微结构在复制品中再现。本发明还涉及根据该方法制成的副本的元件。表面浮雕微结构适于显示具有正 - 负和/或彩色图像翻转的图像。根据本发明的元件对于确保文件和物品防止假冒和伪造特别有用。

97. 发明申请

US20110152336A1 COMBINATION THERAPY WITH PARP INHIBITORS 审中-公开
标题翻译：与PARP抑制剂组合治疗
公开(公告)号：US20110152336A1
公开(公告)日：2011-06-23
申请号：US13037712
申请日：2011-03-01
申请人： Wolfgang Wernet , Thomas D. Penning , Vincent L. Giranda
发明人： Wolfgang Wernet , Thomas D. Penning , Vincent L. Giranda
IPC分类号： A61K31/4184 , A61P35/02
CPC分类号： C07D403/04 , A61K31/41 , A61K31/4164 , A61K41/0038 , A61K45/06 , A61N2005/1098 , A61K2300/00
摘要： The present invention describes benzimidazole derivatives of Formula (I) which constitute potent PARP inhibitors in combination with radiotherapy or in combination with other chemotherapeutic agents.
摘要翻译：本发明描述了式（I）的苯并咪唑衍生物，其与放射治疗组合或与其它化学治疗剂组合地构成有效的PARP抑制剂。

98. 发明申请

US20110151023A1 COMBINATION THERAPY WITH PARP INHIBITORS 审中-公开
公开(公告)号：US20110151023A1
公开(公告)日：2011-06-23
申请号：US13037691
申请日：2011-03-01
申请人： Wolfgang Wernet , Thomas D. Penning , Vincent L. Giranda
发明人： Wolfgang Wernet , Thomas D. Penning , Vincent L. Giranda
IPC分类号： A61K31/4184 , A61K31/437 , A61K33/24 , A61P35/00
CPC分类号： C07D403/04 , A61K31/41 , A61K31/4164 , A61K41/0038 , A61K45/06 , A61N2005/1098 , A61K2300/00
摘要： The present invention describes benzimidazole derivatives of Formula (I) which constitute potent PARP inhibitors in combination with radiotherapy or in combination with other chemotherapeutic agents.

99. 发明申请

US20100041698A1 HETEROCYCLIC COMPOUNDS AND THEIR USE AS BINDING PARTNERS FOR 5-HT5 RECEPTORS 有权
标题翻译：杂环化合物及其作为5-HT5受体的结合合作伙伴使用
公开(公告)号：US20100041698A1
公开(公告)日：2010-02-18
申请号：US11990822
申请日：2006-08-21
申请人： Wilhelm Amberg , Astrid Netz , Andreas Kling , Michael Ochse , Udo Lange , Charles W. Hutchins , Francisco Javier Garcia-Ladona , Wolfgang Wernet , Alfred Hahn
发明人： Wilhelm Amberg , Astrid Netz , Andreas Kling , Michael Ochse , Udo Lange , Charles W. Hutchins , Francisco Javier Garcia-Ladona , Wolfgang Wernet , Alfred Hahn
IPC分类号： A61K31/4706 , C07D215/38 , A61P25/28
CPC分类号： C07D491/056 , C07D215/38 , C07D239/84 , C07D401/04 , C07D401/12 , C07D405/06 , C07D409/04 , C07D409/12 , C07D471/04 , C07D491/04
摘要： The invention relates to compounds of general formula (I), corresponding enantiomeric, diastereomeric and/or tautomeric forms thereof as well as pharmaceutically acceptable salts thereof and the prodrugs of said compounds. The invention also relates to the use of said compounds as binding partners for 5-HT5 receptors for treating diseases that are modulated by a 5-HT5 receptor activity, in particular, for treating neurodegenerative and neuropsychiatric disorders as well as signs, symptoms and dysfunctions.
摘要翻译：本发明涉及通式（I）的化合物，其相应的对映异构体，非对映异构体和/或互变异构形式及其药学上可接受的盐和所述化合物的前药。本发明还涉及所述化合物作为5-HT 5受体的结合伴侣用于治疗受5-HT 5受体活性调节的疾病的用途，特别是用于治疗神经变性和神经精神障碍以及体征，症状和功能障碍。

100. 发明申请

US20080146638A1 COMBINATION THERAPY WITH PARP INHIBITORS 审中-公开
标题翻译：与PARP抑制剂组合治疗
公开(公告)号：US20080146638A1
公开(公告)日：2008-06-19
申请号：US11970828
申请日：2008-01-08
申请人： Vincent L. Giranda , Thomas D. Penning , Wolfgang Wernet , David J. Frost , Cherrie K. Donawho
发明人： Vincent L. Giranda , Thomas D. Penning , Wolfgang Wernet , David J. Frost , Cherrie K. Donawho
IPC分类号： A61K31/4184 , A61P35/00 , A61K31/4188
CPC分类号： A61K31/4188 , A61K31/4184 , A61K2300/00
摘要： The present invention describes benzimidazole derivatives of Formula (I) which constitute potent PARP inhibitors in combination with radiotherapy or in combination with other chemotherapeutic agents.
摘要翻译：本发明描述了式（I）的苯并咪唑衍生物，其与放射治疗组合或与其它化学治疗剂组合地构成有效的PARP抑制剂。

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