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91. 发明授权

US08034821B2 Selective serine/threonine kinase inhibitors 有权
标题翻译：选择性丝氨酸/苏氨酸激酶抑制剂
公开(公告)号：US08034821B2
公开(公告)日：2011-10-11
申请号：US12698027
申请日：2010-02-01
申请人： John William Taunton, Jr. , Michael Cohen , Kevan Shokat , Chao Zhang
发明人： John William Taunton, Jr. , Michael Cohen , Kevan Shokat , Chao Zhang
IPC分类号： C07D487/04 , A61K31/52
CPC分类号： C07D487/04
摘要： Inhibition of protein kinases having one or more cysteine residues within the ATP binding site is effected by contacting the kinase, per se or in a cell or subject, with an inhibitory-effective amount of a compound having a heterocyclic core structure comprised of two or more fused rings containing at least one nitrogen ring atom, and an electrophilic substituent that is capable of reacting with a cysteine residue within the ATP binding site of a kinase.Preferred compounds include certain pyrrolopyrimidines and oxindoles having such an electrophilic substituent and optionally an aromatic or heteroaromatic substituent that is capable of interacting with a threonine or smaller residue located in the gatekeeper position of the kinase.Kinases lacking such cysteine residues may be engineered or modified so that they are capable of being inhibited by such compounds by replacing a valine or other amino acid residue within the ATP binding site by a cysteine residue.
摘要翻译：在ATP结合位点内具有一个或多个半胱氨酸残基的蛋白激酶的抑制通过使本身或细胞或受试者中的激酶与抑制有效量的具有由两个或更多个的杂环核心结构组成的化合物接触来实现含有至少一个氮环原子的稠环，以及能够与激酶的ATP结合位点内的半胱氨酸残基反应的亲电取代基。优选的化合物包括具有这样的亲电子取代基的某些吡咯并嘧啶和羟吲哚，以及任选的能够与位于激酶的关守位置的苏氨酸或更小残基相互作用的芳族或杂芳族取代基。缺乏这种半胱氨酸残基的激酶可以被改造或修饰，使得它们能够被这种化合物抑制，通过用半胱氨酸残基替换ATP结合位点内的缬氨酸或其它氨基酸残基。

92. 发明授权

US07942191B2 Method and system for producing wide steel strip 有权
标题翻译：宽钢带生产方法及系统
公开(公告)号：US07942191B2
公开(公告)日：2011-05-17
申请号：US12780854
申请日：2010-05-14
申请人： Chao Zhang , Zhonghan Luo , Zemin Fang , Jionghui Mao , Shenglin Chen , Ruoping Wang , Xiangxin Wang
发明人： Chao Zhang , Zhonghan Luo , Zemin Fang , Jionghui Mao , Shenglin Chen , Ruoping Wang , Xiangxin Wang
IPC分类号： B22D11/124 , B22D11/126 , B22D27/04 , B21B1/46 , B21B13/22 , C21D8/02
CPC分类号： C21D8/0263 , B21B1/466 , B21B15/005 , B21B45/08 , C21D1/42 , C21D1/74 , C21D8/0215 , C21D8/0226 , Y02P10/253 , Y10T29/49991
摘要： A method for producing a wide steel strip using thin slab continuous casting and rolling by the following steps a) casting a molten steel into a thin slab having a thickness of between 50 and 90 mm; b) cutting; c) soaking; d) heating by electromagnetic induction; e) descaling; f) rolling; g) cooling with laminar flow; and h) coiling. The method can effectively control the solution and precipitation of carbon, nitrogen, and sulfide in steel with a low cost. The process is easy and flexible, and steel can be produced in a wide range of categories. Further provided is a system for producing a wide steel strip with thin slab continuous casting and rolling.
摘要翻译：一种通过以下步骤使用薄板坯连续铸造和轧制生产宽钢带的方法：a）将钢水铸造成厚度在50至90mm的薄板坯; b）切割; c）浸泡; d）电磁感应加热; e）除垢; f）滚动; g）层流冷却; 和h）卷取。该方法可以有效控制钢铁中碳，氮，硫化物的溶解和沉淀，成本低廉。该工艺简单灵活，可生产各种类型的钢。还提供了一种用于生产具有薄板坯连续铸造和轧制的宽钢带的系统。

93. 发明申请

US20110085558A1 Virtual and Logical Inter-Switch Links 有权
标题翻译：虚拟和逻辑交换机间链路
公开(公告)号：US20110085558A1
公开(公告)日：2011-04-14
申请号：US12575608
申请日：2009-10-08
申请人： Sathish Kumar Gnanasekaran , Chao Zhang , Daniel Ji Yong Park Chung , Subramanian Lakshmanan , Badrinath Kollu
发明人： Sathish Kumar Gnanasekaran , Chao Zhang , Daniel Ji Yong Park Chung , Subramanian Lakshmanan , Badrinath Kollu
IPC分类号： H04L12/56
CPC分类号： H04L45/586 , H04L12/4625 , H04L45/583 , H04L49/357 , H04L49/70
摘要： A Layer 2 network switch is partitionable into a plurality of switch fabrics. The single-chassis switch is partitionable into a plurality of logical switches, each associated with one of the virtual fabrics. The logical switches behave as complete and self-contained switches. A logical switch fabric can span multiple single-chassis switch chassis. Logical switches are connected by inter-switch links that can be either dedicated single-chassis links or logical links. An extended inter-switch link can be used to transport traffic for one or more logical inter-switch links. Physical ports of the chassis are assigned to logical switches and are managed by the logical switch. Legacy switches that are not partitionable into logical switches can serve as transit switches between two logical switches.
摘要翻译：二层网络交换机可分割成多个交换结构。单机箱交换机可分割成多个逻辑交换机，每个逻辑交换机与虚拟结构之一相关联。逻辑交换机表现为完整和自包含的交换机。逻辑交换矩阵可以跨多个单机箱交换机机箱。逻辑交换机通过可以是专用单机箱链路或逻辑链路的交换机间链路连接。可以使用扩展的交换机间链路来传输一个或多个逻辑交换机间链路的业务。机箱的物理端口分配给逻辑交换机，由逻辑交换机管理。不可分割到逻辑交换机的旧式交换机可以用作两个逻辑交换机之间的转接交换机。

94. 发明授权

US07491831B2 PPAR active compounds 有权
标题翻译： PPAR活性化合物
公开(公告)号：US07491831B2
公开(公告)日：2009-02-17
申请号：US11679777
申请日：2007-02-27
申请人： Dean R. Artis , Prabha N. Ibrahim , Jack Lin , Chao Zhang
发明人： Dean R. Artis , Prabha N. Ibrahim , Jack Lin , Chao Zhang
IPC分类号： A61K31/40 , A61K31/41 , A61K31/405
CPC分类号： C07D471/04 , C04B35/632 , C07D209/08 , C07D209/12 , C07D209/18 , C07D209/22 , C07D209/26 , C07D231/56 , C07D401/04 , C07D401/12 , C07D405/12 , C07D409/04 , C07D409/12 , C07D487/04
摘要： Compounds are described that are active on PPARs, including pan-active compounds. Also described are methods for developing or identifying compounds having a desired selectivity profile.
摘要翻译：描述了对PPARs有活性的化合物，包括泛活性化合物。还描述了用于开发或鉴定具有所需选择性分布的化合物的方法。

95. 发明申请

US20060047850A1 Multi-chassis, multi-path storage solutions in storage area networks 审中-公开
标题翻译：存储区域网络中的多机箱多路存储解决方案
公开(公告)号：US20060047850A1
公开(公告)日：2006-03-02
申请号：US10931504
申请日：2004-08-31
申请人： Harinder Singh Bhasin , Ambrish Verma , Shreyas Gandhi , Chao Zhang
发明人： Harinder Singh Bhasin , Ambrish Verma , Shreyas Gandhi , Chao Zhang
IPC分类号： G06F17/30
CPC分类号： H04L67/1097 , H04L69/40
摘要： Systems and methods in accordance with various disclosed embodiments are provided for multi-chassis, multi-pathing solutions in storage area networks. A physical target connected to a first storage switch can be virtualized as a member of a virtual logical unit at a second storage switch to which the physical target is not connected. An inter-chassis link can be provided between the storage switches. If the first storage switch becomes inaccessible, the physical target can be accessed via the second storage switch. A virtual logical unit can also be provisioned at the first switch with a member corresponding to the same physical target. The virtual logical units provisioned at each storage switch can be assigned the same identifier to create a clustered virtual logical unit apparent to host devices. Multiple paths to the same logical unit are thus provided to host devices via either switch.
摘要翻译：根据各种公开的实施例的系统和方法被提供用于存储区域网络中的多机箱，多路径解决方案。连接到第一存储交换机的物理目标可以在物理目标未连接到的第二存储交换机上被虚拟化为虚拟逻辑单元的成员。可以在存储交换机之间提供机架间链路。如果第一存储交换机变得不可访问，则可以经由第二存储交换机访问物理目标。虚拟逻辑单元也可以在第一交换机处配置与对应于相同物理目标的成员。在每个存储交换机处提供的虚拟逻辑单元可以被分配相同的标识符以创建对于主机设备而言显着的集群虚拟逻辑单元。因此，通过任一交换机将多个到相同逻辑单元的路径提供给主机设备。

96. 发明申请

US20050246504A1 Reactive deadlock management in storage area networks 有权
标题翻译：存储区域网络中的无效死锁管理
公开(公告)号：US20050246504A1
公开(公告)日：2005-11-03
申请号：US10833457
申请日：2004-04-28
申请人： Robert Frey , Chao Zhang
发明人： Robert Frey , Chao Zhang
IPC分类号： G06F3/06 , G06F12/00
CPC分类号： G06F3/0659 , G06F3/0607 , G06F3/067
摘要： Systems and methods in accordance with various embodiments can detect and alleviate potential or actual deadlock of a storage switch or storage area network when attempting to write data to a mirrored virtual target. In accordance with one embodiment, a timer is started when a storage switch routes a write command to the physical targets corresponding to a virtual target of the write command. If each physical target does not return a transfer ready resource within a predetermined timeout period, the switch determines that a potential or actual deadlock has occurred. An abort command is sent to each of the physical devices. The abort command can clear the command from the targets and also free any allocated transfer ready resources. After receiving an acceptance response from each physical target, the state of the write command at the switch can be cleared. The write command can then be re-issued to the physical devices. In one embodiment, a queue depth for the virtual target can be lowered after failing to receive transfer ready resources from each target. By decreasing the queue depth, the maximum number of commands the switch will process for a virtual target is decreased to decrease the probability of future deadlock. In one embodiment, the queue depth is increased after no deadlock is detected for a period of time.
摘要翻译：根据各种实施例的系统和方法可以在尝试将数据写入到镜像的虚拟目标时，检测和减轻存储交换机或存储区域网络的潜在或实际的死锁。根据一个实施例，当存储交换机将写入命令路由到与写入命令的虚拟目标相对应的物理目标时，启动定时器。如果每个物理目标在预定的超时期间内不返回传送就绪资源，则交换机确定发生了潜在或实际的死锁。将一个中止命令发送到每个物理设备。 abort命令可以清除目标中的命令，并释放任何分配的传输就绪资源。在接收到每个物理目标的接受响应后，可以清除交换机上的写命令的状态。然后可以将write命令重新发送到物理设备。在一个实施例中，在不能从每个目标接收传送就绪资源之后，可以降低虚拟目标的队列深度。通过减少队列深度，减少交换机将为虚拟目标处理的命令的最大数量，以减少未来死锁的概率。在一个实施例中，在一段时间内没有检测到死锁之后，队列深度增加。

97. 发明申请

US20050226626A1 Small form factor pluggable optical transceiver having automatic-restoring unlocking mechanism and mechanism for locating optical transceiver components 有权
标题翻译：小型可插拔光收发器具有自动恢复解锁机构和用于定位光收发器组件的机构
公开(公告)号：US20050226626A1
公开(公告)日：2005-10-13
申请号：US10815326
申请日：2004-04-01
申请人： Chao Zhang , Zhong Yang , Xiaobo Tang , Linhua Zhang , Hongbin Wang
发明人： Chao Zhang , Zhong Yang , Xiaobo Tang , Linhua Zhang , Hongbin Wang
IPC分类号： G02B6/42 , H01R13/629 , H01R13/658 , H04B10/00
CPC分类号： G02B6/4292 , G02B6/4246 , H01R13/62933 , H01R13/659 , H01R13/6594
摘要： An optical transceiver module includes a housing comprising a first end and a second end, an electrical interface associated with the first end and an optical interface associated with the second end. The electrical interface is adapted to be locked into a receiving cage. The optical interface is adapted to be connected with one or more optical transceiver components. The optical transceiver module includes a locating mechanism that restrains the one or more optical transceiver components. The optical transceiver module also includes a locking mechanism that can lock the optical transceiver module to a receiving cage. The optical transceiver module further includes an automatic-restoring unlocking mechanism comprising a sliding plate, an unlocking lever, and a restoration spring, wherein the automatic restoring unlocking mechanism automatically restores the sliding plate to the normal position after the optical transceiver module is unlocked from the receiving cage.
摘要翻译：光收发器模块包括壳体，其包括第一端和第二端，与第一端相关联的电接口和与第二端相关联的光学接口。电接口适于锁定在接收笼中。光学接口适于与一个或多个光收发器组件连接。光收发器模块包括限制一个或多个光收发器组件的定位机构。光收发器模块还包括可将光收发器模块锁定到接收笼的锁定机构。光收发模块还包括自动恢复解锁机构，其包括滑板，解锁杆和恢复弹簧，其中，在光收发模块从所述光收发模块解锁之后，所述自动恢复解锁机构自动将所述滑板恢复到正常位置接收笼

98. 发明授权

US10047058B2 Compounds and methods for inhibiting vacuolar ATPase 有权
公开(公告)号：US10047058B2
公开(公告)日：2018-08-14
申请号：US15384016
申请日：2016-12-19
申请人： Chao Zhang , Ying-Chu Chen
发明人： Chao Zhang , Ying-Chu Chen
IPC分类号： C07D239/94
摘要： A compound of Formula II, is provided. R1, R2 and R3 are independently either hydrogen, alkyl, aryl, halogen, alkoxy, nitro, amino or hydroxyl. X is either F, Cl, Br, I or CN. Y is either N or CH. Compositions that include Formula II can be used to inhibit vacuolar H+ ATPase.

99. 发明申请

US20160321563A1 OPTIMIZED ARTIFICIAL INTELLIGENCE MACHINES THAT ALLOCATE PATROL AGENTS TO MINIMIZE OPPORTUNISTIC CRIME BASED ON LEARNED MODEL 审中-公开
标题翻译：优化人工智能机器，根据学习型号最小化机会性犯罪分配PATROL代理
公开(公告)号：US20160321563A1
公开(公告)日：2016-11-03
申请号：US15144184
申请日：2016-05-02
申请人： Arunesh Sinha , Milind Tambe , Chao Zhang
发明人： Arunesh Sinha , Milind Tambe , Chao Zhang
IPC分类号： G06N99/00 , G06Q50/26
CPC分类号： G06N20/00 , G06N3/008 , G06N7/005 , G06Q50/26
摘要： An optimized artificial intelligence machine may: receive information indicative of the times, locations, and types of crimes that were committed over a period of time in a geographic area; receive information indicative of the number and locations of patrol agents that were patrolling during the period of time; build a learning model based on the received information that learns the relationships between the locations of the patrol agents and the crimes that were committed; and determine whether and where criminals would commit new crimes based on the learning model and a different number of patrol agents or locations of patrol agents. The optimized artificial intelligence machine may determine an optimum location of a pre-determined number of patrolling agents to minimize the number or seriousness of crimes in a geographic area based on the learned model of the relationships between the locations of the patrol agents and the crimes that were committed, and may automatically activate or position one or more of the patrolling agents in accordance with the determination.
摘要翻译：优化的人造智能机器可以：接收指示在一段时间内在地理区域中犯下的犯罪的次数，位置和类型的信息; 收到指示在该段期间巡逻的巡逻人员的人数和地点的资料; 根据收到的信息，建立学习模式，了解巡逻人员的位置与所犯罪行之间的关系; 并根据学习模式和不同数量的巡逻人员或巡逻人员的地点确定犯罪分子是否以及在哪里犯新的罪行。优化的人造智能机器可以基于学习的巡逻人员的位置和犯罪的位置之间的关系的模型来确定预定数量的巡逻者的最佳位置，以最小化地理区域中的犯罪的数量或严重性并且可以根据确定自动激活或定位一个或多个巡逻代理。

100. 发明申请

US20150220742A1 ANTI-THEFT IN FIRMWARE 审中-公开
标题翻译：固件中的反义词
公开(公告)号：US20150220742A1
公开(公告)日：2015-08-06
申请号：US13997369
申请日：2012-10-25
申请人： Qian Ouyang , Jian Javen Wang , Vincent J. Zimmer , Michael A. Rothman , Chao Zhang
发明人： Qian Ouyang , Jian Javen Wang , Vincent J. Zimmer , Michael A. Rothman , Chao Zhang
IPC分类号： G06F21/60 , G06F21/32 , G06F9/44
CPC分类号： G06F21/602 , G06F9/4406 , G06F21/32 , G06F21/575
摘要： Methods, systems and storage media are disclosed for enhanced system boot processing that authenticates boot code based on biometric information of the user before loading the boot code to system memory. For at least some embodiments, the biometric authentication augments authentication of boot code based on a unique platform identifier. The enhanced boot code authentication occurs before loading of the operating system, and may be performed during a Unified Extensible Firmware Interface (UEFI) boot sequence. Other embodiments are described and claimed.
摘要翻译：公开了用于增强的系统引导处理的方法，系统和存储介质，其在将引导代码加载到系统存储器之前，基于用户的生物特征信息认证引导代码。对于至少一些实施例，生物认证认证增强了基于唯一平台标识符的引导代码的认证。增强的引导代码认证在加载操作系统之前发生，并且可以在统一的可扩展固件接口（UEFI）引导序列期间执行。描述和要求保护其他实施例。

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