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91. 发明授权

US08915870B2 Method and system for treating stretch marks 有权
标题翻译：治疗妊娠纹的方法和系统
公开(公告)号：US08915870B2
公开(公告)日：2014-12-23
申请号：US12574512
申请日：2009-10-06
申请人： Peter G. Barthe , Michael H. Slayton , Inder Raj S. Makin
发明人： Peter G. Barthe , Michael H. Slayton , Inder Raj S. Makin
IPC分类号： A61H1/00 , A61B8/14 , A61B8/00 , A61B8/08 , A61H23/02 , A61N7/02 , G01S15/89 , A61N7/00
CPC分类号： A61N7/02 , A61B8/14 , A61B8/4281 , A61B8/429 , A61B8/4444 , A61B8/4455 , A61B8/4483 , A61B8/461 , A61B8/483 , A61B8/5223 , A61B8/54 , A61H23/0245 , A61H2201/0214 , A61H2201/5064 , A61H2201/5082 , A61H2207/00 , A61N2007/0008 , A61N2007/0034 , A61N2007/0052 , A61N2007/0056 , A61N2007/0073 , A61N2007/0078 , G01S15/8909
摘要： Methods and systems for treating stretch marks through deep tissue tightening with ultrasound are provided. An exemplary method and system comprise a therapeutic ultrasound system configured for providing ultrasound treatment to a shallow tissue region, such as a region comprising an epidermis, a dermis and a deep dermis. In accordance with various exemplary embodiments, a therapeutic ultrasound system can be configured to achieve depth from 0 mm to 1 cm with a conformal selective deposition of ultrasound energy without damaging an intervening tissue in the range of frequencies from 2 to 50 MHz. In addition, a therapeutic ultrasound can also be configured in combination with ultrasound imaging or imaging/monitoring capabilities, either separately configured with imaging, therapy and monitoring systems or any level of integration thereof.
摘要翻译：提供了通过深层组织用超声波束紧治疗妊娠纹的方法和系统。示例性方法和系统包括治疗性超声系统，其被配置用于向浅层组织区域提供超声治疗，例如包括表皮，真皮和深层真皮的区域。根据各种示例性实施例，治疗性超声系统可以被配置为通过适形选择性沉积超声能量来实现从0mm至1cm的深度，而不损害在2至50MHz的频率范围内的介入组织。此外，治疗性超声还可以与超声成像或成像/监测能力组合，或者单独配置成像，治疗和监测系统或其任何一体化的结合。

92. 发明授权

US08523775B2 Energy based hyperhidrosis treatment 有权
公开(公告)号：US08523775B2
公开(公告)日：2013-09-03
申请号：US13603279
申请日：2012-09-04
申请人： Peter G. Barthe , Michael H. Slayton , Inder Raj S. Makin
发明人： Peter G. Barthe , Michael H. Slayton , Inder Raj S. Makin
IPC分类号： A61N7/02
CPC分类号： A61N7/02 , A61B8/4281 , A61B17/320068 , A61B2018/00005 , A61N7/00 , A61N2007/0004 , A61N2007/0052 , A61N2007/0078
摘要： A method and system for energy-based (e.g., ultrasound treatment and/or other modalities) of sweat glands are provided. An exemplary method and system for targeted treatment of sweat glands can be configured in various manners, such as through use of therapy only, therapy and monitoring, imaging and therapy, or therapy, imaging, and monitoring, and/or through use of focused, unfocused, or defocused ultrasound (or other energy) through control of various spatial and temporal parameters. As a result, ablative energy can be deposited at the particular depth at which the aberrant sweat gland population is located below the skin surface.

93. 发明授权

US08460193B2 System and method for ultra-high frequency ultrasound treatment 有权
标题翻译：超高频超声处理系统与方法
公开(公告)号：US08460193B2
公开(公告)日：2013-06-11
申请号：US12792934
申请日：2010-06-03
申请人： Peter G. Barthe , Michael H Slayton
发明人： Peter G. Barthe , Michael H Slayton
IPC分类号： A61B8/00
CPC分类号： A61B17/320068 , A61B8/00 , A61H23/0245 , A61N7/02 , A61N2007/0034 , A61N2007/0052
摘要： A non-invasive ultra-high frequency ultrasound treatment method and system are provided. An exemplary method and system comprise a high-frequency ultrasound transducer system configured for providing ultrasound treatment to a patient such that the superficial and/or subcutaneous regions of the patient can be treated. An exemplary high-frequency ultrasound transducer system comprises a control system and a transducer configured to provide treatment to the superficial and/or subcutaneous regions of interest. The high-frequency ultrasound transducer may be configured to operate at higher frequencies and controlled power levels to provide treatment to the superficial and/or subcutaneous regions of interest. For example, higher frequencies within the range from approximately 20 MHz to 500 MHz or more may be utilized.
摘要翻译：提供了非侵入式超高频超声处理方法和系统。示例性方法和系统包括被配置为向患者提供超声治疗使得可以治疗患者的浅表和/或皮下区域的高频超声换能器系统。示例性的高频超声换能器系统包括控制系统和被配置为向感兴趣的表面和/或皮下区域提供治疗的换能器。高频超声换能器可以被配置为在更高的频率和受控的功率水平下操作以对感兴趣的表面和/或皮下区域提供治疗。例如，可以使用在大约20MHz至500MHz或更大的范围内的较高频率。

94. 发明申请

US20130012838A1 SYSTEMS AND METHODS FOR COUPLING AN ULTRASOUND SOURCE TO TISSUE 有权
标题翻译：用于将超声波源与组织联接的系统和方法
公开(公告)号：US20130012838A1
公开(公告)日：2013-01-10
申请号：US13547023
申请日：2012-07-11
申请人： Paul Jaeger , Peter G. Barthe , Michael H. Slayton
发明人： Paul Jaeger , Peter G. Barthe , Michael H. Slayton
IPC分类号： A61N7/00
CPC分类号： A61N7/02 , A61B8/429 , A61B8/56 , A61B2018/00642 , A61B2018/00898 , A61B2090/378 , A61N2007/0034 , A61N2007/006 , A61N2007/0091 , A61N2007/0095 , A61N2007/027
摘要： Various embodiments provide a system for providing a constant average output of power from an ultrasound source. In some embodiments, the system comprises an ultrasound transducer coupled to a power supply; a controller in communication with the power supply; a chirp function in communication with and operable to monitor the ultrasound transducer; a feedback loop from the chirp function to the controller. In some embodiments, the controller is operable to change a parameter on the transducer based on the feedback to provide a constant average output of power from the ultrasound transducer.
摘要翻译：各种实施例提供一种用于从超声源提供恒定的平均功率输出的系统。在一些实施例中，该系统包括耦合到电源的超声换能器; 与电源通信的控制器; 与所述超声换能器通信并且可操作地监视所述超声换能器的啁啾功能; 从啁啾功能到控制器的反馈回路。在一些实施例中，控制器可操作以基于反馈改变换能器上的参数，以提供来自超声换能器的功率的恒定平均输出。

95. 发明申请

US20130012816A1 METHODS AND SYSTEMS FOR CONTROLLING ACOUSTIC ENERGY DEPOSITION INTO A MEDIUM 审中-公开
标题翻译：将声学能量沉积控制在介质中的方法和系统
公开(公告)号：US20130012816A1
公开(公告)日：2013-01-10
申请号：US13545931
申请日：2012-07-10
申请人： Michael H. Slayton , Peter G. Barthe
发明人： Michael H. Slayton , Peter G. Barthe
IPC分类号： A61N7/02 , A61N5/02 , A61N5/06 , A61N7/00 , A61B8/13
CPC分类号： A61N7/00 , A61B18/18 , A61B2018/00642 , A61M37/0092 , A61N7/02 , A61N2007/0004 , A61N2007/0017 , A61N2007/0034 , A61N2007/0039 , A61N2007/0052 , A61N2007/006 , A61N2007/0073 , A61N2007/0078 , A61N2007/027
摘要： A method and system for acoustic treatment of tissue are provided. Acoustic energy, including ultrasound, under proper functional control can penetrate deeply and be controlled precisely in tissue. In some embodiments, methods and systems are configured for acoustic tissue treatment based on creating an energy distribution function in tissue. In some embodiments, methods and systems are configured based on creating a temperature distribution function in tissue.
摘要翻译：提供了一种用于组织声学处理的方法和系统。包括超声在内的声能在适当的功能控制下可以深入渗透并精确控制在组织中。在一些实施例中，方法和系统被配置用于基于在组织中产生能量分布函数的声学组织处理。在一些实施例中，基于在组织中产生温度分布函数来配置方法和系统。

96. 发明申请

US20120330223A1 ENERGY BASED HYPERHIDROSIS TREATMENT 有权
标题翻译：基于能量的高血压治疗
公开(公告)号：US20120330223A1
公开(公告)日：2012-12-27
申请号：US13603279
申请日：2012-09-04
申请人： Inder Raj S. Makin , Peter G. Barthe , Michael H. Slayton
发明人： Inder Raj S. Makin , Peter G. Barthe , Michael H. Slayton
IPC分类号： A61B18/04 , A61M37/00
CPC分类号： A61N7/02 , A61B8/4281 , A61B17/320068 , A61B2018/00005 , A61N7/00 , A61N2007/0004 , A61N2007/0052 , A61N2007/0078
摘要： A method and system for energy-based (e.g., ultrasound treatment and/or other modalities) of sweat glands are provided. An exemplary method and system for targeted treatment of sweat glands can be configured in various manners, such as through use of therapy only, therapy and monitoring, imaging and therapy, or therapy, imaging, and monitoring, and/or through use of focused, unfocused, or defocused ultrasound (or other energy) through control of various spatial and temporal parameters. As a result, ablative energy can be deposited at the particular depth at which the aberrant sweat gland population is located below the skin surface.
摘要翻译：提供了一种用于基于能量的方法和系统（例如，超声治疗和/或其他方式）的汗腺。用于针对性治疗汗腺的示例性方法和系统可以以各种方式配置，例如仅通过使用治疗，治疗和监测，成像和治疗，或治疗，成像和监测，和/或通过使用聚焦，未聚焦或散焦超声（或其他能量）通过控制各种空间和时间参数。因此，可以在异常汗腺群体位于皮肤表面下方的特定深度沉积烧蚀能量。

97. 发明申请

US20120059288A1 METHOD AND SYSTEM FOR ULTRASOUND TREATMENT WITH A MULTI-DIRECTIONAL TRANSDUCER 有权
标题翻译：用于多方向传感器超声处理的方法和系统
公开(公告)号：US20120059288A1
公开(公告)日：2012-03-08
申请号：US13294004
申请日：2011-11-10
申请人： Peter G. Barthe , Michael H. Slayton
发明人： Peter G. Barthe , Michael H. Slayton
IPC分类号： A61N7/00
CPC分类号： A61N7/022 , A61B8/4272 , A61B2017/00084 , A61B2090/378 , A61N2007/0078
摘要： A method and system for ultrasound treatment utilizing a multi-directional transducer to facilitate treatment, such as therapy and/or imaging or other tissue parameter monitoring, in two or more directions. In accordance with an exemplary embodiment, a multi-directional transducer comprises at least two transduction elements configured to provide for ultrasound energy, such as radiation, acoustical energy, heat energy, imaging, positional information and/or tissue parameter monitoring signals in two or more directions. The transduction elements can comprise various materials for providing ultrasound energy or radiation, such as piezoelectric materials, with and without matching layers. In addition, the transduction elements can be configured for substantially uniform, focused and/or defocused radiation patterns, as well as for single, multiple-element and/or multiple-element array configurations. In addition, an exemplary multi-directional transducer can comprise multiple elements, either side by side, stacked or in an array.
摘要翻译：一种利用多向换能器来促进诸如在两个或更多个方向上的治疗和/或成像或其它组织参数监测的治疗的超声治疗的方法和系统。根据示例性实施例，多向换能器包括至少两个换能元件，所述至少两个换能元件被配置为提供两个或更多个超声能量的超声能量，例如辐射，声能，热能，成像，位置信息和/或组织参数监测信号方向。转导元件可以包括用于提供超声能量或辐射的各种材料，例如具有和不具有匹配层的压电材料。此外，转导元件可以被配置为基本上均匀的，聚焦的和/或散焦的辐射图，以及用于单个，多元件和/或多元件阵列配置。此外，示例性多向换能器可以包括多个元件，并排，堆叠或阵列。

98. 发明申请

US20120029353A1 Systems and methods for ultrasound treatment 有权
标题翻译：超声治疗的系统和方法
公开(公告)号：US20120029353A1
公开(公告)日：2012-02-02
申请号：US13136544
申请日：2011-08-02
申请人： Michael H. Slayton , Peter G. Barthe
发明人： Michael H. Slayton , Peter G. Barthe
IPC分类号： A61N7/00 , A61B8/13
CPC分类号： A61N7/00 , A61B8/13 , A61B8/14 , A61B8/4254 , A61B8/4272 , A61B8/485 , A61B8/5246 , A61B17/320068 , A61B2018/00642 , A61B2018/00898 , A61B2090/378 , A61N7/02 , A61N2007/0013 , A61N2007/0034 , A61N2007/0052 , A61N2007/006 , A61N2007/0065 , A61N2007/0091 , A61N2007/0095 , A61N2007/027
摘要： Various embodiments provide a method for an extended field of view treatment. The method can include the steps of imaging a region; targeting a region with directed ultrasound energy; monitoring the region; moving the imaging, treatment, and monitoring region while spatially correlating to one or more prior regions via imaging and/or position sensing; continuing the extended field of view treatment; and, achieving an ultrasound induced biological effect in the extended field of view treatment region.
摘要翻译：各种实施例提供了一种用于扩展视野处理的方法。该方法可以包括对区域进行成像的步骤; 针对具有定向超声能量的区域; 监测该地区; 移动成像，处理和监视区域，同时通过成像和/或位置感测与一个或多个先前区域空间相关; 继续扩大视野治疗; 并在扩展视野区域实现超声诱导生物学效应。

99. 发明申请

US20110178444A1 METHODS AND SYSTEMS FOR GENERATING THERMAL BUBBLES FOR IMPROVED ULTRASOUND IMAGING AND THERAPY 有权
标题翻译：用于生成改善超声成像和治疗的热泡的方法和系统
公开(公告)号：US20110178444A1
公开(公告)日：2011-07-21
申请号：US12954484
申请日：2010-11-24
申请人： Michael H. Slayton , Peter G. Barthe , Inder Raj S. Makin
发明人： Michael H. Slayton , Peter G. Barthe , Inder Raj S. Makin
IPC分类号： A61N7/02
CPC分类号： A61N7/00 , A61B8/4281 , A61B8/4472 , A61B8/48 , A61B2018/00005 , A61B2018/00642 , A61N5/0616 , A61N5/10 , A61N2007/0039 , A61N2007/0043 , A61N2007/0056 , A61N2007/006 , A61N2007/0065 , A61N2007/0073
摘要： A method and system uniquely capable of generating thermal bubbles for improved ultrasound imaging and therapy. Several embodiments of the method and system contemplates the use of unfocused, focused, or defocused acoustic energy at variable spatial and/or temporal energy settings, in the range of about 1 kHz-100 MHz, and at variable tissue depths. The unique ability to customize acoustic energy output and target a particular region of interest makes possible highly accurate and precise thermal bubble formation. In an embodiment, the energy is acoustic energy. In other embodiments, the energy is photon based energy (e.g., IPL, LED, laser, white light, etc.), or other energy forms, such radio frequency electric currents (including monopolar and bipolar radio-frequency current). In an embodiment, the energy is various combinations of acoustic energy, electromagnetic energy and other energy forms or energy absorbers such as cooling.
摘要翻译：一种独特地产生热气泡以改进超声成像和治疗的方法和系统。该方法和系统的几个实施例考虑在约1kHz-100MHz的范围内和在可变组织深度处的可变空间和/或时间能量设置下使用未聚焦，聚焦或散焦的声能。定制声能输出和瞄准特定感兴趣区域的独特能力使得高精度和精确的热气泡形成成为可能。在一个实施例中，能量是声能。在其他实施例中，能量是基于光子的能量（例如，IPL，LED，激光，白光等）或其他能量形式，例如射频电流（包括单极性和双极性射频电流）。在一个实施例中，能量是声能，电磁能和其它能量形式或诸如冷却的能量吸收器的各种组合。

100. 发明授权

US07883468B2 Medical system having an ultrasound source and an acoustic coupling medium 有权
标题翻译：具有超声波源和声耦合介质的医疗系统
公开(公告)号：US07883468B2
公开(公告)日：2011-02-08
申请号：US10848550
申请日：2004-05-18
申请人： Inder Raj S. Makin , T. Douglas Mast , Michael H. Slayton , Peter G. Barthe , Jeffrey D. Messerly , Waseem Faidi , Megan M. Runk
发明人： Inder Raj S. Makin , T. Douglas Mast , Michael H. Slayton , Peter G. Barthe , Jeffrey D. Messerly , Waseem Faidi , Megan M. Runk
IPC分类号： A61B8/00
CPC分类号： A61B8/4272 , A61B8/12 , A61B8/4281 , A61B8/4444 , A61B8/546 , A61B2017/2253 , A61N7/00 , A61N7/022 , A61N2007/0052
摘要： An ultrasound medical system has an end effector including a medical ultrasound transducer and an acoustic coupling medium. The acoustic coupling medium has a transducer-proximal surface and a transducer-distal surface. The medical ultrasound transducer is positioned to emit medical ultrasound through the acoustic coupling medium from the transducer-proximal surface to the transducer-distal surface. The end effector is adapted to change a property (such as the shape and/or the temperature) of the acoustic coupling medium during emission, and/or between emissions, of medical ultrasound from the medical ultrasound transducer during a medical procedure on a patient. In one example, such changes are used to change the focus and/or beam angle of the emitted ultrasound during the medical procedure.
摘要翻译：超声波医疗系统具有包括医用超声波换能器和声耦合介质的末端执行器。声耦合介质具有换能器近侧表面和换能器远侧表面。医疗超声换能器被定位成通过声耦合介质从换能器近端表面到换能器远侧表面发射医用超声波。端部执行器适于在医疗超声波换能器在患者的医疗过程期间改变声学耦合介质在发射期间和/或发射之间的医疗超声波的性质（例如形状和/或温度）。在一个示例中，这样的改变用于在医疗过程期间改变发射的超声的焦点和/或束角。

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