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91. 发明专利

MX2010006643A PROTEINAS DEL METABOLISMO DE LOS LIPIDOS, COMBINACIONES DE PROTEINAS DEL METABOLISMO DE LOS LIPIDOS Y SUS USOS. 未知
公开(公告)号：MX2010006643A
公开(公告)日：2010-08-02
申请号：MX2010006643
申请日：2008-12-10
申请人： BASF PLANT SCIENCE GMBH
发明人： ZANK THORSTEN , PLESCH GUNNAR , PUZIO PIOTR , BLAU ASTRID , WENDEL BIRGIT , KAMLAGE BEATE , OSWALD OLIVER , HEROLD MICHAEL MANFRED , SCHAUWECKER FLORIAN , WETJEN TOM
IPC分类号： C12N15/82
摘要： En el campo de la ingeniería genética en plantas se describen, incluso combinaciones de polinucleótidos que codifican LMP para mejorar los rasgos agronómicos, hortícolas y de calidad. También a la combinación de polinucleótidos que codifican proteínas que se relacionan con la presencia de compuestos de almacenamiento en semillas en plantas. Más específicamente, con polinucleótidos LMP que codifican proteínas del metabolismo de los lípidos (LMP) y el uso de estas combinaciones de estas secuencias, su orden y dirección en la combinación, y los elementos reguladores utilizados para el control de la expresión y la terminación de la transcripción en estas combinaciones en las plantas transgénicas. En particular, a métodos para manipular compuestos relacionados con ácidos grasos y para aumentar los niveles de aceite y almidón, y para alterar la composición de ácidos grasos en plantas y semillas. Además a métodos para utilizar estas nuevas combinaciones de polipéptidos para estimular el crecimiento de la planta y/o el crecimiento de la raíz y/o para aumentar el rendimiento y/o la composición de compuestos de almacenamiento en semillas.

92. 发明专利

MX2009003824A PLANTAS CON RENDIMIENTO AUMENTADO. 未知
公开(公告)号：MX2009003824A
公开(公告)日：2010-04-07
申请号：MX2009003824
申请日：2007-10-12
申请人： BASF PLANT SCIENCE GMBH
发明人： ZANK THORSTEN , BAUER JORG , OSWALD OLIVER , ZRENNER RITA MARIA , KOSLOWSKY SILKE
IPC分类号： C12N15/82
摘要： Esta invenci?n se refiere por lo general a c?lulas vegetales y/o plantas con rendimiento aumentado en comparaci?n con una c?lula vegetal de tipo silvestre no transformada correspondiente al aumentar o generar una o m?s actividades de polip?ptidos asociados con el fosforibosilpirofosfato (PRPP) intermedio en plantas. En particular, esta invenci?n se refiere a c?lulas vegetales y/o plantas con rendimiento aumentado en comparaci?n con una c?lula vegetal de tipo silvestre no transformada correspondiente al aumentar o generar una o m?s actividades de fosforibosilo pirofosfato sintasa (PRPP sintetasa, PRS). La invenci?n tambi?n trata con m?todos de producir y seleccionar y criar dichas c?lulas vegetales y/o plantas.

93. 发明专利

CA2567132A1 PROCESS FOR THE PRODUCTION OF .DELTA.5-UNSATURATED FATTY ACIDS IN TRANSGENIC ORGANISMS 未知
公开(公告)号：CA2567132A1
公开(公告)日：2007-05-24
申请号：CA2567132
申请日：2006-11-23
申请人： BASF PLANT SCIENCE GMBH
发明人： ZANK THORSTEN , SAYANOVA OLGA , NAPIER JOHNATHAN A
IPC分类号： C12N15/53 , A01H5/00 , A01K67/027 , C12N1/00 , C12N5/10 , C12N9/02 , C12N9/10 , C12N15/54 , C12N15/63 , C12N15/79 , C12P7/64
摘要： A process for the production of .DELTA.5-unsaturated fatty acids in transgen ic organisms comprises transforming an organism with nucleic acid encoding a .DELTA.5- desaturase.

94. 发明专利

CA2615837A1 COMBINATION OF LIPID METABOLISM PROTEINS AND USES THEREOF 未知
公开(公告)号：CA2615837A1
公开(公告)日：2007-02-01
申请号：CA2615837
申请日：2006-07-14
申请人： BASF PLANT SCIENCE GMBH
发明人： OSWALD OLIVER , ZANK THORSTEN
IPC分类号： C12N15/82 , A01H5/00
摘要： Described herein are inventions in the field of genetic engineering of plants, including combinations of nucleic acid molecules encoding LMPs to improve agronomic, horticultural, and quality traits. This invention relates generally to the combination of nucleic acid sequences encoding proteins that are related to the presence of seed storage compounds in plants. More specifically, the present invention relates to LMP nucleic acid sequences encoding lipid metabolism proteins (LMP) and the use of these combinations of these sequences, their order and direction in the combination, and the regulatory elements used to control expression and transcript termination in these combinations in transgenic plants. In particular, the invention is directed to methods for manipulating fatty acid-related compounds and for increasing oil level and altering the fatty acid composition in plants and seeds. The invention further relates to methods of using these novel combinations of polypeptides to stimulate plant growth and/or to increase yield and/or composition of seed storage compounds.

95. 发明专利

NO20181488A1 Fremgangsmåte for fremstilling av flerumettede fettsyrer i transgene organismer. 未知
公开(公告)号：NO20181488A1
公开(公告)日：2006-02-24
申请号：NO20181488
申请日：2018-11-21
申请人： BASF PLANT SCIENCE GMBH
发明人： HEINZ ERNST , SPERLING PETRA , CIRPUS PETRA , DOMERGUE FREDERIC , ZANK THORSTEN , BAUER JÖRG , QIU ZIAO , VRINTEN PATRICIA , MEYER ASTRID , KIRSCH JELENA , ABBADI AMINE
IPC分类号： A23D9/00 , A23D9/02 , A23L33/115 , C11B1/00 , C11B1/02 , C12N9/02 , C12N9/10 , C12N15/82 , C12P7/64
摘要： Foreliggende oppfinnelse angår en fremgangsmåte for produksjon av flerumettede fettsyrer i en organisme ved innføring i organismen, nukleinsyrer som koder for polypeptider med Δ5-elongase-aktivitet. Fordelaktig kan disse nukleinsyresekvenser uttrykkes i organismen, hvis det passer sammen med ytterligere nukleinsyresekvenser som koder for polypeptider av biosyntese av fettsyre- eller lipid-metabolisme. Spesielt fordelaktig er nukleinsyresekvenser som koder for en Δ6-desaturase-, Δ5-desaturase-, Δ4-desaturase- og/eller Δ6-elongase-aktivitet. Disse desaturaser og elongaser er fordelaktig avledet fra Thalassiosira, Euglena eller Ostreococcus. Oppfinnelsen angår videre en fremgangsmåte for fremstilling av oljer og/eller triacylglycerider med et forhøyet innhold av langkjedede flerumettede fettsyrer. I en foretrukket utførelsesform angår foreliggende oppfinnelse videre en metode for fremstilling av umettede ω3-fettsyrer og en metode for fremstilling av triglycerider med et forhøyet innhold av umettede fettsyrer, spesielt ω3-fettsyrer med mer enn tre dobbeltbindinger. Oppfinnelsen angår dannelse av en transgen organisme, fortrinnsvis en transgen plante eller en transgen mikroorganisme, med et forhøyet innhold av umettet ω3-fettsyrer, oljer eller lipider med ω3-dobbeltbindinger som resultat av ekspresjon av elongaser og desaturaser anvendt ved fremgangsmåten ifølge oppfinnelsen, fordelaktig sammen med ω3-desaturaser, for eksempel en ω3-desaturase fra sopper av familien Pythiaceae så som slekten Phytophthora, for eksempel slekten og arten Phytophthora infestans eller en ω3-desaturase fra alger så som familien Prasinophyceae, for eksempel slekten Ostreococcus, spesifikt slekten og arten Ostreococcus tauri eller diatoméer så som slekten Thalassiosira, spesifikt slekten og arten Thalassiosira pseudonana. Oppfinnelsen angår videre nukleinsyresekvenser, nukleinsyrekonstruksjoner, vektorer og organismer omfattende nukleinsyresekvensene ifølge oppfinnelsen, vektorer omfattende nukleinsyresekvensene og/eller nukleinsyrekontruksjonene og transgene organismer omfattende de ovennevnte nukleinsyresekvenser, nukleinsyrekonstruksjoner og/eller vektorer. En ytterligere del av oppfinnelsen angår oljer, lipider og/eller fettsyrer produsert ved fremgangsmåten ifølge oppfinnelsen og anvendelse av dem. Oppfinnelsen angår videre umettede fettsyrer og triglycerider med et forhøyet innhold av umettede fettsyrer og anvendelse av dem.

96. 发明专利

CA2548944A1 SUGAR AND LIPID METABOLISM REGULATORS IN PLANTS VI 未知
公开(公告)号：CA2548944A1
公开(公告)日：2005-07-14
申请号：CA2548944
申请日：2004-12-22
申请人： BASF PLANT SCIENCE GMBH
发明人： BAUER JORG , ZANK THORSTEN , OSWALD OLIVER
IPC分类号： C12N15/82 , A01H5/00
摘要： Isolated nucleic acids and proteins associated with lipid and sugar metaboli sm regulation are provided. In particular, lipid metabolism proteins (LMP) and encoding nucleic acids originating from Arabidopsis thaliana, Brassica napus , and Helianthus annuus are provided. The nucleic acids and proteins are used in methods of producing transgenic plants and modulating levels of seed storage compounds. Preferably, the seed storage compounds are lipids, fatty acids, starches, or seed storage proteins.

97. 发明专利

NO20053149D0 未知
公开(公告)号：NO20053149D0
公开(公告)日：2005-06-28
申请号：NO20053149
申请日：2005-06-28
申请人： BASF PLANT SCIENCE GMBH
发明人： HEINZ ERNST , RENZ ANDREAS , DOMERGUE FREDERIC , ZANK THORSTEN , ABBADI AMINE
IPC分类号： C12N9/10 , C12N15/82 , C12P7/64 , C12N
摘要： The present invention relates to a process for producing polyunsaturated fatty acids in an organism by introducing nucleic acids into the organism which code for polypeptides having acyl-CoA:lysophospholipid a cyltransferase activity. Advantageously, these nucleic acid sequences may, if appropriate together with further nucleic acid sequences coding for biosynthesis polypeptides of the fatty acid or lipid metabolism, be expressed in the transgenic organism. The invention furthermore relates to the nucleic acid sequences, to nucleic acid constructs comprising the nucleic acid sequences of the invention, to vectors comprising the nucleic acid sequences and/or the nucleic acid constructs and to transgenic organisms comprising the abovementioned nucleic acid sequences, nucleic acid constructs and/or vectors. A further part of the invention relates to oils, lipids and/or fatty acids produced by the process of the invention and to their use.

98. 发明专利

CA2998666A1 METHOD FOR THE PRODUCTION OF MULTIPLY-UNSATURATED FATTY ACIDS IN TRANSGENIC ORGANISMS 未知
公开(公告)号：CA2998666A1
公开(公告)日：2005-02-10
申请号：CA2998666
申请日：2004-07-16
申请人： BASF PLANT SCIENCE GMBH
发明人： ZANK THORSTEN , BAUER JORG , CIRPUS PETRA , ABBADI AMINE , HEINZ ERNST , QIU XIAO , VRINTEN PATRICIA , SPERLING PETRA , DOMERGUE FREDERIC , MEYER ASTRID , KIRSCH JELENA
IPC分类号： C12N15/53 , A01H5/00 , A23D9/00 , A23K20/158 , A23L33/115 , A61K8/36 , A61K31/202 , C11B1/02 , C12N5/10 , C12N9/00 , C12N9/02 , C12N9/10 , C12N15/52 , C12N15/82 , C12P7/64
摘要： Producing polyunsaturated fatty acids (I) comprises introducing nucleic acid sequences coding for delta 9 elongase or delta 6 desaturase, delta 8 desaturase or delta 6 elongase, delta 5 desaturase, delta 5 elongase and delta 4 desaturase activity into an organism to produce a transgenic organism whose total lipids include at least 1 wt.% (I). Producing polyunsaturated fatty acids of formula (I) comprises introducing nucleic acid sequences coding for delta 9 elongase or delta 6 desaturase, delta 8 desaturase or delta 6 elongase, delta 5 desaturase, delta 5 elongase and delta 4 desaturase activity into an organism to produce a transgenic organism whose total lipids include at least 1 wt.% of formula (I). [Image] R 1>OH, coenzyme A (thioester), lysophosphatidyl choline, lysophosphatidyl ethanolamine, lysophosphatidyl glycerol, lysophosphatidyl serine, lysophosphatidyl inositol, sphingobase or OCH 2CH(OR 3>)CH 2OR 2>; R 2>H, lysophosphatidyl choline, lysophosphatidyl ethanolamine, lysophosphatidyl glycerol, lysophosphatidyl serine, lysophosphatidyl inositol, (un)saturated 2-24C alkylcarbonyl or CO(CH 2) n(CH=CHCH 2) m(CH 2) pCH 3; R 3>H, (un)saturated 2-24C alkylcarbonyl or CO(CH 2) n(CH=CHCH 2) m(CH 2) pCH 3; n : 2-9; m : 2-6; p : 0 or 3. Independent claims are also included for: (1) oils, lipids or fatty acids produced as above; (2) oil, lipid or fatty acid composition that comprises polyunsaturated fatty acids produced as above and is derived from transgenic plants; (3) isolated nucleic acid sequence coding for a delta 5 elongase polypeptide having one of 6 amino acid sequences given in the specification; (4) isolated nucleic acid sequence that codes for a delta 6 elongase polypeptide and has one of 4 nucleotide sequences given in the specification; (5) isolated nucleic acid sequence that codes for a omega 3 desaturase polypeptide and has one of 2 nucleotide sequences given in the specification; (6) isolated nucleic acid sequence that codes for a delta 6 desaturase polypeptide and has one of 2 nucleotide sequences given in the specification; (7) isolated nucleic acid sequence that codes for a delta 5 desaturase polypeptide and has one of 4 nucleotide sequences given in the specification; (8) isolated nucleic acid sequence that codes for a delta 4 desaturase polypeptide and has one of 2 nucleotide sequences given in the specification; (9) isolated nucleic acid sequence that codes for a delta 12 desaturase polypeptide and has one of 2 nucleotide sequences given in the specification; (10) amino acid sequence encoded by an isolated nucleic acid sequence as above; (11) genetic construct comprising an isolated nucleic acid as above linked to one or more regulatory signals; (12) vector containing a nucleic acid or construct as above; (13) transgenic non-human organism containing a nucleic acid, construct or vector as above.

99. 发明专利

AU2004215705A1 Method for the production of polyunsaturated fatty acids 未知
公开(公告)号：AU2004215705A1
公开(公告)日：2004-09-10
申请号：AU2004215705
申请日：2004-01-29
申请人： BASF PLANT SCIENCE GMBH
发明人： DOMERGUE FREDERIC , ZANK THORSTEN , RENZ ANDREAS , HEINZ ERNST , ABBADI AMINE
IPC分类号： C12N9/10 , C12N15/82 , C12P7/64
摘要： The present invention relates to a process for producing polyunsaturated fatty acids in an organism by introducing nucleic acids into the organism which code for polypeptides having acyl-CoA:lysophospholipid a cyltransferase activity. Advantageously, these nucleic acid sequences may, if appropriate together with further nucleic acid sequences coding for biosynthesis polypeptides of the fatty acid or lipid metabolism, be expressed in the transgenic organism. The invention furthermore relates to the nucleic acid sequences, to nucleic acid constructs comprising the nucleic acid sequences of the invention, to vectors comprising the nucleic acid sequences and/or the nucleic acid constructs and to transgenic organisms comprising the abovementioned nucleic acid sequences, nucleic acid constructs and/or vectors. A further part of the invention relates to oils, lipids and/or fatty acids produced by the process of the invention and to their use.

100. 发明专利

CA2474163A1 ELONGASE GENE AND METHOD FOR PRODUCING POLYUNSATURATED FATTY ACIDS 未知
公开(公告)号：CA2474163A1
公开(公告)日：2003-08-07
申请号：CA2474163
申请日：2003-01-13
申请人： BASF PLANT SCIENCE GMBH
发明人： LERCHL JENS , HEINZ ERNST , ZANK THORSTEN
IPC分类号： A01H5/00 , A23D9/00 , A23K1/16 , A61K8/30 , A61K8/36 , A61K31/201 , A61K31/202 , A61P9/00 , A61P29/00 , C12N9/00 , C12N9/10 , C12N15/09 , C12N15/82 , C12P7/64 , A23K1/00 , C12N1/00 , C12N9/02 , A61K31/20 , A23L1/30
摘要： The invention relates to a novel elongase gene comprising the sequence SEQ ID NO:1 or the homologues, derivatives or analogues thereof, to a gene construct comprising said gene or the homologues, derivatives or analogues thereof, and to the use of the same. The invention also relates to vectors or organisms having an elongase gene comprising the sequence SEQ ID NO:1 or the homologues, derivatives or analogues thereof. The invention further relates to a method for producing polyunsaturated fatty acids and to a method for introducing DNA into organisms which produce large quantities of oils, especially oils having a high unsaturated fatty acid content. Disclosed is also an oil and/or a fatty acid composition having a higher content of polyunsaturated fatty acids comprising at least two double bonds, and/or a triacylglycerine composition having a higher content of polyunsaturated fatty acids comprising at least two double bonds.

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