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    • 97. 发明申请
    • MAGNETIC PARTICLES FOR DELIVERING THERAPEUTIC AGENT TO A TARGET LOCATION
    • 用于将治疗药物递送至目标位置的磁性颗粒
    • US20100269838A1
    • 2010-10-28
    • US12765369
    • 2010-04-22
    • Aiden FlanaganKent HarrisonLiliana AtanasoskaDavid SogardLiza Davis
    • Aiden FlanaganKent HarrisonLiliana AtanasoskaDavid SogardLiza Davis
    • A61B19/00
    • A61K9/0009A61K9/1676A61K9/501A61K9/5094A61K9/5115
    • A system for delivering therapeutic agent to a target location in a body in accordance with one embodiment is provided comprising a plurality of magnetic particles, each magnetic particle carrying a therapeutic agent, and a magnetic device for attracting the magnetic particles to a target location. The magnetic particles may be delivered by a catheter into a blood vessel upstream from the target location so that they travel toward the target location. A method for delivering therapeutic agent to a target location in a body in accordance with another embodiment comprises providing a plurality of magnetic particles, each magnetic particle carrying a therapeutic agent, placing a magnetic device in a position to attract the magnetic particles to a target location, and allowing the magnetic particles to infuse the target location by the attraction of the magnetic particles to the magnetic device. The therapeutic agent may comprises a therapeutic agent for preventing or treating reperfusion injury, and the step of providing the plurality of magnetic particles may comprise delivering the plurality of magnetic particles through a blood vessel.
    • 提供了根据一个实施例的用于将治疗剂递送到身体中的目标位置的系统,其包括多个磁性颗粒,每个携带治疗剂的磁性颗粒和用于将磁性颗粒吸引到目标位置的磁性装置。 磁性颗粒可以通过导管输送到目标位置上游的血管中,使得它们朝向目标位置行进。 根据另一实施例的用于将治疗剂递送到身体中的目标位置的方法包括提供多个磁性颗粒,每个磁性颗粒携带治疗剂,将磁性装置放置在将磁性颗粒吸引到目标位置的位置 ,并且允许磁性颗粒通过磁性颗粒吸引到磁性装置来注入目标位置。 治疗剂可以包括用于预防或治疗再灌注损伤的治疗剂,并且提供多个磁性颗粒的步骤可以包括通过血管递送多个磁性颗粒。