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91. 发明申请

US20200377413A1 CEMENT AND SOLID WASTE FILLER MATERIAL 审中-公开
公开(公告)号：US20200377413A1
公开(公告)日：2020-12-03
申请号：US16423538
申请日：2019-05-28
申请人： David Clark
发明人： David Clark
IPC分类号： C04B18/04 , C04B26/00
摘要： A filler material includes a combination of a cement and a solid waste. The solid waste is in a proportion of about 6% up to about 94% of the filler material. The filler material can be used to strengthen the stability of landfills.

92. 发明申请

US20200291041A1 PCSK9 Inhibitors and Methods of Use Thereof 审中-公开
公开(公告)号：US20200291041A1
公开(公告)日：2020-09-17
申请号：US16744929
申请日：2020-01-16
申请人： Michael H. Serrano-Wu , Mark Chambers , Erica Goldsmith , Jason Tierney , Karamjit Jandu , David Clark , Paul Hinchliffe
发明人： Michael H. Serrano-Wu , Mark Chambers , Erica Goldsmith , Jason Tierney , Karamjit Jandu , David Clark , Paul Hinchliffe
IPC分类号： C07D491/107 , C07D417/12 , C07D417/14 , C07D487/10 , C07D498/04 , C07D471/10 , C07D471/04 , C07D401/14 , C07D403/14 , C07D495/04 , A61P9/00 , A61P3/06
摘要： The invention relates to novel heteroaryl compounds and pharmaceutical preparations thereof. The invention further relates to methods of treating or preventing cardiovascular diseases, and methods treating sepsis or septic shock, using the novel heterocyclic compounds disclosed herein.

93. 发明授权

US09702969B2 Ultrasonic blood flow doppler audio with pitch shifting 有权
公开(公告)号：US09702969B2
公开(公告)日：2017-07-11
申请号：US13320233
申请日：2010-04-19
申请人： David Hope Simpson , David Clark , Anup Agarwal
发明人： David Hope Simpson , David Clark , Anup Agarwal
IPC分类号： A61B8/00 , G01S7/52 , A61B8/06 , A61B8/08 , G01S15/89
CPC分类号： G01S7/52066 , A61B8/06 , A61B8/488 , G01S15/8979
摘要： An ultrasonic diagnostic imaging system produces audio Doppler from detected Doppler signals. The Doppler signals are detected in a band of frequencies which corresponds to the velocity of blood flow signals, and Doppler information is displayed based on the detected band of frequencies. The audio Doppler system produces Doppler audio in a frequency band which is shifted in pitch from the detected band of frequencies. The operator of the ultrasound system is provided with a user control by which the degree of pitch shifting can be controlled. The ultrasound system displays Doppler blood flow velocities referenced to a transmit Doppler frequency f0, with the audio Doppler being shifted in pitch from the frequencies corresponding to the blood flow velocities.

94. 发明授权

US09226918B2 Methods and compositions for treating or preventing narcotic withdrawal symptoms 有权
标题翻译：用于治疗或预防麻醉戒断症状的方法和组合物
公开(公告)号：US09226918B2
公开(公告)日：2016-01-05
申请号：US12631628
申请日：2009-12-04
申请人： Gary Peltz , David Clark , Lawrence Chu
发明人： Gary Peltz , David Clark , Lawrence Chu
IPC分类号： A61K31/485 , A61K31/4178 , A61K31/444 , A61K31/495
CPC分类号： A61K31/4178 , A61K31/444 , A61K31/485 , A61K31/495 , A61K2300/00
摘要： This invention provides methods and pharmaceutical compositions for preventing or treating physical dependence and/or withdrawal associated with narcotic use, in particular by modulating a 5-HT3 receptor. Using a computational genetic approach in mice, a gene conserved between mice and humans was identified as candidate as a modulator of physical dependence to morphine. Administration of compounds that modulate 5-HT3 receptors was found to control withdrawal from morphine in mice and humans.
摘要翻译：本发明提供了用于预防或治疗与麻醉药物使用相关的身体依赖和/或戒断的方法和药物组合物，特别是通过调节5-HT 3受体。在小鼠中使用计算遗传学方法，将小鼠和人之间保守的基因鉴定为作为吗啡物理依赖的调节剂的候选物。发现调节5-HT 3受体的化合物的给药可以控制小鼠和人类的吗啡戒断。

95. 发明申请

US20150327514A1 SYSTEM AND DEVICE FOR DISPENSING PET REWARDS 审中-公开
公开(公告)号：US20150327514A1
公开(公告)日：2015-11-19
申请号：US14280577
申请日：2014-05-17
申请人： David Clark , Simon Milner , Tom Daniel Lorey
发明人： David Clark , Simon Milner , Tom Daniel Lorey
IPC分类号： A01K15/02 , H04N7/18 , G08C17/02 , A01K5/02
CPC分类号： A01K5/02 , A01K15/021 , A01K15/025 , G08C17/02 , G08C2201/32 , H04N7/183
摘要： A device for and method to provide pet rewards. The device includes a sound apparatus to alert a pet that a reward is about to be dispensed and a video camera wirelessly coupled to a remote user device to view the pet and the dispensing of a reward. Remote control of sounds, treat delivery, and pet viewing over a wireless connection can be provided with and through a user device. The method include connecting to a wireless network, a remote use device connection to the device, and the user device sending commands for sending video data, outputting sounds, and dispensing pet-rewards.

96. 发明授权

US08813289B1 Modular wheelchair ramp including double-channeled stringer 有权
标题翻译：模块化轮椅斜坡，包括双通道纵梁
公开(公告)号：US08813289B1
公开(公告)日：2014-08-26
申请号：US14049132
申请日：2013-10-08
申请人： David Clark , Brian Clark , Paul Clark
发明人： David Clark , Brian Clark , Paul Clark
IPC分类号： E01D19/00 , E04F11/00
CPC分类号： E04F11/002
摘要： An easy-to-construct modular wheelchair ramp with reliable dimensional stability in excess of all current regulatory requirements is provided. Such a modular device allows for a variety of ramp materials to be incorporated therein on demand as well as the utilization of any desired ramp pitch without any need to adjust (let alone actually use) connecting brackets and/or under-section supports. The double-channel stringer configuration thus allows for support legs to easily connect and move along such a component for facilitated set-up. Additionally, the double-channeled structure allows for any handrail materials to be properly and easily secured thereto. The stringer alone, as well as the overall modular ramp structure, are encompassed within this invention. The method of constructing such a wheelchair ramp is also envisioned within the invention.
摘要翻译：提供了一种容易构造的模块化轮椅坡道，其尺寸稳定性可靠性超过目前的所有法规要求。这种模块化装置允许根据需要将各种斜坡材料并入其中，以及利用任何所需的斜坡间距，而不需要调整（更不用说实际使用）连接支架和/或底部支撑。因此，双通道纵梁构造允许支撑腿容易地沿着这种部件连接和移动以便于安装。此外，双通道结构允许任何扶手材料适当且容易地固定到其上。单独的纵梁以及整个模块化斜坡结构都包含在本发明内。在本发明中也设想了构成这种轮椅坡道的方法。

97. 发明申请

US20130233398A1 Air Inductor for Gutter Downspout 审中-公开
标题翻译：空气电感器用于沟槽下水道
公开(公告)号：US20130233398A1
公开(公告)日：2013-09-12
申请号：US13682827
申请日：2012-11-21
申请人： David Clark
发明人： David Clark
IPC分类号： E04D13/076
CPC分类号： E04D13/076 , E04D2013/0866 , Y10T137/0396 , Y10T137/3185
摘要： An air induction device is provided for mounting to a downspout to induce the flow of air in the downspout. The air induction device comprises a tubular member that is sealingly fitted through the downspout such that it provides fluid communication between the atmosphere and the interior of the downspout. The air induction device is preferably mounted on an upwardly facing surface of the downspout and at a location where the downspout is extending angularly downward or at a bend in the downspout, thereby orienting the tubular member at an upwardly extending oblique angle relative to the downspout.
摘要翻译：提供一种空气感应装置用于安装到下水口以引起下水口中的空气流。空气感应装置包括一个管状构件，该管状构件通过下水口密封地配合，使得它提供了大气与下水口内部之间的流体连通。空气感应装置优选地安装在下水口的面向上的表面上，并且在下水口成角度地向下或在下降管的弯曲处延伸的位置处，从而使管状构件相对于下水口以向上延伸的倾斜角定向。

98. 发明申请

US20120083247A1 System And Methods For Wireless Messaging 有权
标题翻译：无线信息系统和方法
公开(公告)号：US20120083247A1
公开(公告)日：2012-04-05
申请号：US13316008
申请日：2011-12-09
申请人： David P. Yach , Gary P. Mousseau , David Clark , Scotte Zinn , Michael Hardy , Nataliya Martsyna
发明人： David P. Yach , Gary P. Mousseau , David Clark , Scotte Zinn , Michael Hardy , Nataliya Martsyna
IPC分类号： H04W4/12
CPC分类号： H04W4/12 , H04L51/38
摘要： A mobile device receives via a wireless network an enable message which indicates that a data message has been received and is ready for retrieval. The mobile device then provides an indication which indicates that the data message has been received, and includes a subset of the data message. After providing the indication, the mobile device detects a user-initiated entry into a messaging application. In response to detecting the user-initiated entry, the mobile device examines a setting in a data store which is provided in response to the enable message. If the setting is provided in the data store, the mobile device requests the data message by sending via the wireless network a fetch message and subsequently receives the data message. If the setting is not provided in the data store, the mobile device refrains from sending the fetch message.
摘要翻译：移动设备经由无线网络接收指示已经接收到数据消息并且可以进行检索的启用消息。然后，移动设备提供指示已经接收到数据消息的指示，并且包括数据消息的子集。在提供指示之后，移动设备检测用户发起的进入消息应用程序的条目。响应于检测到用户发起的条目，移动设备检查响应于启用消息而提供的数据存储中的设置。如果在数据存储器中提供设置，则移动设备通过经由无线网络发送获取消息来请求数据消息，并随后接收数据消息。如果在数据存储中未提供该设置，则移动设备不发送提取消息。

99. 发明申请

US20120059264A1 ULTRASONIC BLOOD FLOW DOPPLER AUDIO WITH PITCH SHIFTING 有权
标题翻译：超声波流量多普勒音频与PITCH移位
公开(公告)号：US20120059264A1
公开(公告)日：2012-03-08
申请号：US13320233
申请日：2010-04-19
申请人： David Hope Simpson , David Clark , Anup Agarwal
发明人： David Hope Simpson , David Clark , Anup Agarwal
IPC分类号： A61B8/06
CPC分类号： G01S7/52066 , A61B8/06 , A61B8/488 , G01S15/8979
摘要： An ultrasonic diagnostic imaging system produces audio Doppler from detected Doppler signals. The Doppler signals are detected in a band of frequencies which corresponds to the velocity of blood flow signals, and Doppler information is displayed based on the detected band of frequencies. The audio Doppler system produces Doppler audio in a frequency band which is shifted in pitch from the detected band of frequencies. The operator of the ultrasound system is provided with a user control by which the degree of pitch shifting can be controlled. The ultrasound system displays Doppler blood flow velocities referenced to a transmit Doppler frequency f0, with the audio Doppler being shifted in pitch from the frequencies corresponding to the blood flow velocities.
摘要翻译：超声诊断成像系统从检测到的多普勒信号产生音频多普勒。在对应于血流信号的速度的频带中检测多普勒信号，并且基于检测到的频带显示多普勒信息。音频多普勒系统在从所检测的频带中以音调偏移的频带中产生多普勒音频。超声系统的操作者设置有可以控制音调移位程度的用户控制。超声系统显示参照发射多普勒频率f0的多普勒血流速度，其中音频多普勒频率从对应于血流速度的频率偏移。

100. 发明授权

US07848751B2 System and methods for data communications in a wireless communication system 有权
标题翻译：用于无线通信系统中数据通信的系统和方法
公开(公告)号：US07848751B2
公开(公告)日：2010-12-07
申请号：US12622849
申请日：2009-11-20
申请人： David Clark , Allan David Lewis , Barry Gilhuly , David Bajar , Nataliya Martsyna , Rob Maurice
发明人： David Clark , Allan David Lewis , Barry Gilhuly , David Bajar , Nataliya Martsyna , Rob Maurice
IPC分类号： H04W4/00
CPC分类号： H04W8/06 , H04L51/18 , H04L51/38 , H04L67/04 , H04L67/14 , H04L67/142 , H04L67/18 , H04L67/303 , H04W4/12 , H04W88/02
摘要： In one embodiment, a mobile communication device is configured to selectively enable user data communications after registration in a wireless communication network. The mobile device sends, via its radio, feature compliance information to the network. In response to the feature compliance information being sent, the mobile device receives, via the radio, configuration information which is derived based on the feature compliance information and location information of the mobile device. The mobile device then selectively enables the user data communications based on the received configuration information. In particular, the mobile device enables the user data communications when the location information indicates that the mobile device is operating in a particular country and the feature compliance information indicates feature compliance for the particular country. On the other hand, the mobile device disables the user data communications when the location information indicates that the mobile device is operating in the particular country and the feature compliance information indicates a lack of feature compliance for the particular country.
摘要翻译：在一个实施例中，移动通信设备被配置为在无线通信网络中注册之后有选择地启用用户数据通信。移动设备通过其无线电将特征符合性信息发送到网络。响应于正在发送的特征合规信息，移动设备经由无线电接收基于特征合规性信息和移动设备的位置信息导出的配置信息。然后，移动设备基于接收到的配置信息选择性地启用用户数据通信。特别地，当位置信息指示移动设备在特定国家/地区运行时，移动设备能够进行用户数据通信，并且特征符合性信息指示特定国家的特征符合性。另一方面，当位置信息指示移动设备在特定国家/地区运行时，移动设备禁用用户数据通信，并且特征符合性信息指示特定国家缺乏特征符合性。

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