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91. 发明申请

US20120158023A1 Endoscopic Suture Cinch System 有权
标题翻译：内窥镜缝合线系统
公开(公告)号：US20120158023A1
公开(公告)日：2012-06-21
申请号：US12970323
申请日：2010-12-16
申请人： Vladimir Mitelberg , Donald K. Jones
发明人： Vladimir Mitelberg , Donald K. Jones
IPC分类号： A61B17/04
CPC分类号： A61B17/0487 , A61B17/0467 , A61B17/0469 , A61B17/0485 , A61B17/0625 , A61B2017/00296 , A61B2017/0417 , A61B2017/0464 , A61B2017/0488
摘要： A two-part suture cinch includes a collar and a plug. A cinch applicator is also provided, and includes an elongate tubular member, a plunger engaged within the distal end of the tubular member, a flexible shaft extending through the tubular member and plunger, and a proximal handle for moving the shaft longitudinally relative to the tubular member. The plunger includes a distal housing for the collar of the cinch, and the plug is coupled to the distal end of the flexible shaft. The suture is thread through the collar and a portion of the applicator. Operation of the applicator draws the plug into the collar and clamps the suture between the plug and collar. In addition, once the plug is coupled in to the collar, the plunger is displaced proximally to release the two-part cinch form the applicator. A method for applying the cinch is also provided.
摘要翻译：两部分缝合线包括一个领和一个插头。还提供了一种系带施放器，包括细长的管状构件，接合在管状构件的远端内的柱塞，延伸穿过管状构件和柱塞的柔性轴以及用于相对于管状物纵向移动轴的近侧手柄会员。柱塞包括用于衣领的衣领的远侧壳体，并且塞子联接到柔性轴的远端。缝合线穿过套环和一部分敷贴器。施加器的操作将插头拉入套环并将缝合线夹在插头和套环之间。此外，一旦插头联接到套环中，柱塞向近端移位以释放施加器的两部分紧身衣形式。还提供了一种应用该系带的方法。

92. 发明申请

US20100286723A1 CHEMICALLY BASED VASCULAR OCCLUSION DEVICE DEPLOYMENT 失效
标题翻译：基于化学的血管造影装置部署
公开(公告)号：US20100286723A1
公开(公告)日：2010-11-11
申请号：US12839143
申请日：2010-07-19
申请人： Donald K. Jones , Vladimir Mitelberg
发明人： Donald K. Jones , Vladimir Mitelberg
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/12109 , A61B17/1214 , A61B2017/12081
摘要： A vascular occlusion device deployment system for placing an occlusion device at a preselected site within the vasculature of a patient. The deployment system employing a pusher having a lumen with an opening at the distal end of the pusher. A vascular occlusion device is connected to the distal end of the pusher by a portion that is removeably disposed within the opening. The portion of the occlusion device is forced out of the opening by an expandable reaction chamber, thereby deploying the occlusion device.
摘要翻译：一种血管闭塞装置展开系统，用于将闭塞装置放置在患者脉管系统内的预选部位。采用具有在推动器的远端具有开口的内腔的推动器的展开系统。血管闭塞装置通过可移除地设置在开口内的部分连接到推动器的远端。闭塞装置的部分被可膨胀的反应室从开口压出，从而展开闭塞装置。

93. 发明授权

US07811305B2 Stretch resistant embolic coil delivery system with spring release mechanism 有权
标题翻译：具弹簧释放机构的抗张力线栓输送系统
公开(公告)号：US07811305B2
公开(公告)日：2010-10-12
申请号：US11395700
申请日：2006-03-31
申请人： Keith Balgobin , Donald K. Jones , Vladimir Mitelberg , John H. Thinnes, Jr.
发明人： Keith Balgobin , Donald K. Jones , Vladimir Mitelberg , John H. Thinnes, Jr.
IPC分类号： A61M29/00 , A61F2/06
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12154 , A61B2017/00477 , A61B2017/00862 , A61B2017/12054
摘要： A medical device for placing an embolic device at a predetermined site within a vessel of the body including a delivery catheter and a flexible pusher member slidably disposed within the lumen of the catheter. An embolic device is retained within the delivery catheter by a mechanical interlocking mechanism which includes an engagement member attached to the distal end of the pusher member and extends through a retaining ring at the proximal end of the embolic device. A detachment member extends through an aperture at the distal end of the engagement member thereby locking the embolic device onto the pusher member. A kicker member, which takes the form of a helical spring, extends from the distal end of the pusher member and is biased so as to lift the retaining ring off of the engagement member to ensure the release of the embolic device when the detachment member is withdrawn from the aperture of the engagement member.
摘要翻译：一种用于将栓塞装置放置在主体容器内的预定位置处的医疗装置，包括输送导管和可滑动地设置在导管内腔内的柔性推动器构件。栓塞装置通过机械互锁机构保持在输送导管内，该机械互锁机构包括附接到推动器构件的远端的接合构件并延伸穿过栓塞装置的近端处的保持环。分离构件延伸穿过接合构件的远端处的孔，从而将栓塞装置锁定到推动器构件上。采取螺旋弹簧形式的起动器构件从推动器构件的远端延伸并且被偏置以便将保持环从接合构件提升离开以确保当分离构件是释放构件时释放栓塞装置从接合构件的孔中取出。

94. 发明授权

US07670353B2 Modified headpiece for hydraulic coil deployment system 有权
标题翻译：液压线圈展开系统改装头
公开(公告)号：US07670353B2
公开(公告)日：2010-03-02
申请号：US11423525
申请日：2006-06-12
申请人： Richard Champion Davis, III , Donald K. Jones , Vladimir Mitelberg
发明人： Richard Champion Davis, III , Donald K. Jones , Vladimir Mitelberg
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/1214 , A61B17/1219 , A61B2017/00539 , A61B2017/1205 , A61B2017/12054
摘要： A vascular occlusion device for use with a hydraulic deployment catheter is provided. The vascular occlusion device includes a headpiece that has a deformable interference element which changes from an initial configuration to a deformed configuration upon an increase of hydraulic pressure within the deployment catheter. When the interference element is in the initial configuration, the headpiece is secured to the deployment catheter, and when the interference element is in the deformed configuration, the headpiece can be removed from the deployment catheter for deployment of the occlusion device.
摘要翻译：提供了一种与液压展开导管一起使用的血管闭塞装置。血管闭塞装置包括具有可变形干扰元件的头盔，该可变形干涉元件在展开导管内的液压增加时从初始构型变化到变形构型。当干涉元件处于初始构造时，头盔被固定到展开导管，并且当干涉元件处于变形构型时，头盔可以从用于展开遮挡装置的展开导管移除。

95. 发明授权

US07608088B2 Stent aneurysm embolization device 有权
标题翻译：支架动脉瘤栓塞装置
公开(公告)号：US07608088B2
公开(公告)日：2009-10-27
申请号：US10874954
申请日：2004-06-23
申请人： Donald K. Jones , Vladimir Mitelberg
发明人： Donald K. Jones , Vladimir Mitelberg
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/12118 , A61B17/12145 , A61B17/12172 , A61B2017/1205
摘要： A method and device used for treating an aneurysm of a patient. A framework for supporting one or more embolization elements is introduced into the patient's aneurysm. A stent, connected to the framework is introduced into a vessel leading into and communicating with the aneurysm, with the stent being compressed against the inner wall of the vessel for anchoring the framework. One or more embolization elements are introduced through the framework into the aneurysm, and in this manner the framework maintains the one or more embolization elements within the aneurysm. In the illustrative embodiment, the embolization element comprises an embolic coil, the stent comprises a helical coil, and the framework and helical coil are connected so as to be introduced into the patient simultaneously.
摘要翻译：用于治疗患者动脉瘤的方法和装置。支持一个或多个栓塞元件的框架被引入患者的动脉瘤。连接到框架的支架被引入到导管和与动脉瘤连通的容器中，支架被压靠在容器的内壁上以锚固框架。通过框架将一个或多个栓塞元件引入动脉瘤，并且以这种方式，框架维持动脉瘤内的一个或多个栓塞元件。在说明性实施例中，栓塞元件包括栓塞线圈，支架包括螺旋线圈，框架和螺旋线圈连接以同时引入患者。

96. 发明授权

US07591833B2 Laser-based vascular occlusion device detachment system 失效
标题翻译：基于激光的血管闭塞装置分离系统
公开(公告)号：US07591833B2
公开(公告)日：2009-09-22
申请号：US11171898
申请日：2005-06-30
申请人： Donald K. Jones , Vladimir Mitelberg
发明人： Donald K. Jones , Vladimir Mitelberg
IPC分类号： A61M29/00
CPC分类号： A61B17/12022 , A61B17/1214 , A61B2017/00477 , A61B2017/12072
摘要： A vascular occlusion device deployment system for placing an occlusion device at a preselected site within the vasculature of a patient. The deployment system employing light energy transferred through an optical fiber to sever a securing filament attaching the occlusion device to the deployment system, thereby releasing the occlusion device at the preselected location.
摘要翻译：一种血管闭塞装置展开系统，用于将闭塞装置放置在患者脉管系统内的预选部位。采用通过光纤传输的光能的部署系统来切断将遮挡装置附接到展开系统的固定细丝，从而将遮挡装置释放在预选位置。

97. 发明申请

US20090018603A1 Methods and Systems for Submucosal Implantation of a Device for Diagnosis and Treatment of a Body 有权
标题翻译：用于身体诊断和治疗的装置的粘膜下植入的方法和系统
公开(公告)号：US20090018603A1
公开(公告)日：2009-01-15
申请号：US11776062
申请日：2007-07-11
申请人： Vladimir Mitelberg , Donald K. Jones , Brett E. Naglreiter , Dennis L. McWilliams
发明人： Vladimir Mitelberg , Donald K. Jones , Brett E. Naglreiter , Dennis L. McWilliams
IPC分类号： A61N1/02 , A61B17/94
CPC分类号： A61B17/320016 , A61B17/068 , A61B17/3468 , A61B17/3478 , A61B17/3496 , A61B2017/00269 , A61B2017/00818 , A61B2017/2937 , A61B2017/320048 , A61B2017/320056 , A61F2002/30668 , A61F2250/0001 , A61M25/0084 , A61M25/10 , A61N1/0509 , A61N1/36007 , A61N1/37217
摘要： Instruments, systems and methods are provided for performing submucosal medical procedures in a desired area of the digestive tract using endoscopy. Instruments include a safe access needle injection instrument, a submucosal tunneling instrument, a submucosal dissection instrument, and a mucosal resection device. Systems include a combination of one or more of such instruments with or without injectable agents. Embodiments of various methods for performing the procedures are also provided. In accordance with one aspect there is provided a submucosal implant device for diagnosing and treating disorders of the body. The submucosal implant device may take the form of a gastric stimulator in which signals are supplied to the muscular wall of a mammal to treat motility disorders. In accordance with yet another aspect there is provided a method for performing a submucosal medical procedure to deploy a submucosal implant device in the digestive tract of a mammal.
摘要翻译：提供了仪器，系统和方法，用于使用内窥镜检查在消化道的期望区域中进行粘膜下的医学过程。仪器包括安全进针针注射器械，粘膜下隧道仪器，粘膜下剥离仪器和粘膜切除装置。系统包括具有或不具有可注射剂的一种或多种这样的仪器的组合。还提供了用于执行该过程的各种方法的实施例。根据一个方面，提供了一种用于诊断和治疗身体疾病的粘膜下植入装置。粘膜下植入装置可以采取胃刺激剂的形式，其中向哺乳动物的肌肉壁提供信号以治疗运动障碍。根据另一方面，提供了一种用于执行粘膜下部医疗程序以在哺乳动物的消化道中部署粘膜下植入装置的方法。

98. 发明授权

US07371252B2 Stretch resistant embolic coil delivery system with mechanical release mechanism 有权
标题翻译：具有机械释放机制的抗拉伸栓塞线圈输送系统
公开(公告)号：US07371252B2
公开(公告)日：2008-05-13
申请号：US11301664
申请日：2005-12-13
申请人： Keith Balgobin , Donald K. Jones , Vladimir Mitelberg , Darren R. Sherman , John H. Thinnes, Jr.
发明人： Keith Balgobin , Donald K. Jones , Vladimir Mitelberg , Darren R. Sherman , John H. Thinnes, Jr.
IPC分类号： A61M29/00 , A91F2/06
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12154 , A61B2017/00477 , A61B2017/00867 , A61B2017/12054
摘要： A medical device for placing an embolic device, such as an embolic coil at a predetermined site within a vessel of the body including a delivery catheter and a flexible pusher member slidably disposed within the lumen of the catheter. An embolic device is retained within the delivery catheter by a mechanical interlocking mechanism which includes a deflectable engagement member attached to the distal end of the pusher member and extends through a retaining ring at the proximal end of the embolic device. A detachment member extends through an aperture at the distal end of the engagement member thereby locking the embolic device onto the pusher member. When the detachment member is withdrawn from the aperture of the engagement member the engagement member deflects to release the embolic device.
摘要翻译：一种用于将栓塞装置（例如栓塞线圈）放置在主体容器内的预定位置处的医疗装置，包括输送导管和可滑动地设置在导管内腔内的柔性推动器构件。栓塞装置通过机械互锁机构保持在输送导管内，该机械联锁机构包括附接到推动器构件的远端的可偏转接合构件，并且延伸穿过栓塞装置的近端处的保持环。分离构件延伸穿过接合构件的远端处的孔，从而将栓塞装置锁定到推动器构件上。当分离构件从接合构件的孔中取出时，接合构件偏转以释放栓塞装置。

99. 发明授权

US07371251B2 Stretch resistant embolic coil delivery system with mechanical release mechanism 有权
标题翻译：具有机械释放机制的抗拉伸栓塞线圈输送系统
公开(公告)号：US07371251B2
公开(公告)日：2008-05-13
申请号：US11143052
申请日：2005-06-02
申请人： Vladimir Mitelberg , Donald K. Jones , Juan A. Lorenzo
发明人： Vladimir Mitelberg , Donald K. Jones , Juan A. Lorenzo
IPC分类号： A61M29/00 , A61F2/06
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12154 , A61B2017/1205 , A61B2017/12054
摘要： A medical device for placing an embolic device at a predetermined site within a vessel of the body including a delivery catheter and a flexible pusher member having a lumen therethrough and being slidably disposed within the lumen of the catheter. A stretch resistant embolic device is retained within the delivery catheter by a mechanical interlocking mechanism which includes an engagement member which is attached to the distal end of the pusher member and extends through a retaining ring at the proximal end of the embolic device. A detachment member extends through an aperture at the distal end of the engagement member thereby locking the embolic device onto the pusher member. The engagement member engages a retaining ring on the embolic device. When the embolic device is advanced to the predetermined site within the vessel, the detachment member is withdrawn from the aperture to thereby release the embolic device at the treatment site.
摘要翻译：一种用于将栓塞装置放置在身体的容器内的预定位置处的医疗装置，包括输送导管和具有通过其的腔的柔性推动器构件，并且可滑动地设置在导管的腔内。弹性阻塞栓塞装置通过机械互锁机构保持在输送导管内，该机械互锁机构包括接合构件，该接合构件附接到推动器构件的远端并延伸穿过栓塞装置的近端处的保持环。分离构件延伸穿过接合构件的远端处的孔，从而将栓塞装置锁定到推动器构件上。接合构件接合栓塞装置上的保持环。当栓塞装置前进到血管内的预定位置时，分离构件从孔中取出，从而在治疗部位释放栓塞装置。

100. 发明授权

US07367987B2 Stretch resistant embolic coil delivery system with mechanical release mechanism 有权
标题翻译：具有机械释放机制的抗拉伸栓塞线圈输送系统
公开(公告)号：US07367987B2
公开(公告)日：2008-05-06
申请号：US11301865
申请日：2005-12-12
申请人： Keith Balgobin , Donald K. Jones , Vladimir Mitelberg , Darren R. Sherman , John H. Thinnes, Jr.
发明人： Keith Balgobin , Donald K. Jones , Vladimir Mitelberg , Darren R. Sherman , John H. Thinnes, Jr.
IPC分类号： A61M29/00 , A61F2/06
CPC分类号： A61B17/12022 , A61B17/12113 , A61B17/12154 , A61B2017/00477 , A61B2017/00862 , A61B2017/12054
摘要： A medical device for placing an embolic device at a predetermined site within a vessel of the body including a delivery catheter and a flexible pusher member slidably disposed within the lumen of the catheter. An embolic device is retained within the delivery catheter by a mechanical interlocking mechanism which includes an engagement member attached to the distal end of the pusher member and extends through a retaining ring at the proximal end of the embolic device. A detachment member extends through an aperture at the distal end of the engagement member thereby locking the embolic device onto the pusher member. A kicker member extends from the distal end of the pusher member and is biased so as to lift the retaining ring off of the engagement member to ensure the release of the embolic device when the detachment member is withdrawn from the aperture of the engagement member.
摘要翻译：一种用于将栓塞装置放置在主体容器内的预定位置处的医疗装置，包括输送导管和可滑动地设置在导管内腔内的柔性推动器构件。栓塞装置通过机械互锁机构保持在输送导管内，该机械互锁机构包括附接到推动器构件的远端的接合构件并延伸穿过栓塞装置的近端处的保持环。分离构件延伸穿过接合构件的远端处的孔，从而将栓塞装置锁定到推动器构件上。推动器构件从推动器构件的远端延伸并且被偏压以便将保持环从接合构件提起，以确保当分离构件从接合构件的孔中取出时栓塞装置的释放。

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