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91. 发明授权

US06517498B1 Apparatus and method for tissue capture 有权
标题翻译：用于组织捕获的装置和方法
公开(公告)号：US06517498B1
公开(公告)日：2003-02-11
申请号：US09619867
申请日：2000-07-20
申请人： Fred H. Burbank , William C. Homet , Paul Lubock
发明人： Fred H. Burbank , William C. Homet , Paul Lubock
IPC分类号： A61B1000
CPC分类号： A61B10/0233 , A61B10/02 , A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1482 , A61B18/1487 , A61B18/1492 , A61B90/37 , A61B2010/0208 , A61B2010/0225 , A61B2017/32004 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： A tissue acquisition system includes electrodes that are energized by a radio frequency (RF) energy source. Retractable electrodes are energized and extended from a cannula and the cannula is advanced in the tissue to position the cannula near the target tissue site in a patient. The retractable electrodes are then retracted and a distal electrode cuts a tissue sample from the tissue site when the cannula is further advanced into the tissue. The retractable electrodes are then energized and extended from the cannula and the cannula is rotated to separate the tissue sample from the tissue site. The tissue sample is ejected through the cannula for collection by advancing a dilator.
摘要翻译：组织采集系统包括由射频（RF）能源激励的电极。可伸缩电极通电并从套管延伸，并且插管在组织中前进以将插管定位在患者体内的目标组织部位附近。然后，当套管进一步推进到组织中时，缩回电极然后缩回并且远侧电极从组织部位切割组织样本。然后可伸缩电极从插管通电并延伸，并且套管旋转以从组织部位分离组织样品。通过推进扩张器将组织样品通过套管喷射以进行收集。

92. 发明授权

US06454727B1 Tissue acquisition system and method of use 有权
公开(公告)号：US06454727B1
公开(公告)日：2002-09-24
申请号：US09196125
申请日：1998-11-20
申请人： Fred Burbank , Paul Lubock , Michael L. Jones , Martin V. Shabaz
发明人： Fred Burbank , Paul Lubock , Michael L. Jones , Martin V. Shabaz
IPC分类号： A61B500
CPC分类号： A61B10/0233 , A61B10/02 , A61B10/0266 , A61B10/0275 , A61B10/0283 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1482 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B2010/0225 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/144 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： A tissue acquisition system includes radio frequency (RF) cutter loops which are extendable out a cannula to cut cylindrical tissue samples from a tissue of interest in a patient. The cannula includes inner and outer cannulae which are mutually rotatable and include cutouts through which the cutting loop can be rotated and longitudinally extended to perform the cuts. The tissue samples are then aspirated proximally through the cannula for collection.

93. 发明授权

US06312429B1 Electrosurgical lesion location device 失效
公开(公告)号：US06312429B1
公开(公告)日：2001-11-06
申请号：US09356187
申请日：1999-07-16
申请人： Fred H. Burbank , Frank R. Louw , Paul Lubock , Richard L. Quick
发明人： Fred H. Burbank , Frank R. Louw , Paul Lubock , Richard L. Quick
IPC分类号： A61B1818
CPC分类号： A61B10/0266 , A61B10/02 , A61B17/00491 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/14 , A61B18/1477 , A61B18/1487 , A61B18/1492 , A61B90/17 , A61B90/37 , A61B90/39 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/1475 , A61B2018/162 , A61B2090/3908
摘要： A device for localizing a target tissue mass in a body includes a tubular trocar portion having a distal end and a proximal end portion that is removably attachable to a handle portion. The trocar portion contains at least a first plurality of locator wires that are movable between a retracted position within the trocar and a deployed position extending radially from the trocar. In a preferred embodiment, the trocar portion has an electrosurgical cutting element at its distal end, and first and second pluralities of locator wires that, when deployed, respectively define first and second locating perimeters. The first plurality of locator wires is connected to a first wire carrying member longitudinally mounted for axial movement within the trocar portion between a proximal position corresponding to the retracted position of the first plurality of locator wires, and a distal position corresponding to the deployed position of the first plurality of locator wires. The second plurality of locator wires is connected to a second wire-carrying member longitudinally mounted in the trocar portion, coaxially with the first tubular member, for movement between a distal position corresponding to the retracted position of the second plurality of locator wires, and a proximal position corresponding to the deployed position of the second plurality of locator wires. The trocar portion has an intermediate portion having first and second pluralities of slot-shaped apertures through which the first and second pluralities of locator wires emerge when moved to their respective deployed positions. With the locator wires in their retracted position, the trocar is passed through a target tissue mass until the intermediate portion is within the mass. The locator wires are then deployed within the mass to anchor the trocar therein and to mark the site for a surgical procedure. In the preferred embodiment, the locator wires are electrically energized to facilitate their deployment electrosurgically.

94. 发明授权

US5836955A Wound closure apparatus and method 失效
公开(公告)号：US5836955A
公开(公告)日：1998-11-17
申请号：US891916
申请日：1997-07-14
申请人： Terrence J. Buelna , Wayne A. Noda , Paul Lubock
发明人： Terrence J. Buelna , Wayne A. Noda , Paul Lubock
IPC分类号： A61B17/00 , A61B17/04
CPC分类号： A61B17/0469 , A61B17/04 , A61B17/0483 , A61B17/062 , A61B17/0625 , A61B17/0057 , A61B17/0482 , A61B2017/00349 , A61B2017/00637 , A61B2017/00663 , A61B2017/00672 , A61B2017/047 , A61B2017/0472
摘要： Apparatus for suturing a wound in a body cannula having an axis extending between a proximal end and a distal end. A handle is disposed at the proximal end and a pair of needles disposed at the distal end, the needles being movable between a proximal position and a distal position. A suture manipulator carried by the cannula is insertable through the wound and operable to manipulate the suture into an engaging relationship with the needles on the far side of the body wall. In one embodiment of the invention, a finger ring is movable on the handle in a single distal direction through multiple stages. In a first stage the needles are deployed; in a second stage, the suture manipulator is activated to thread the needles; and in a third stage the suture is released from a tensioning mechanism. In another embodiment, the finger ring is movable in a distal direction to deploy and thread the needles, and movable in a proximal direction to tension the suture and withdraw the needles. In an associated method the needles are threaded on the far side of the body wall and withdrawn from the wound providing access to the suture ends on the near side of the body wall. Tying the suture ends closes the wound.

95. 发明授权

US5460629A Electrosurgical device and method 失效
标题翻译：电外科装置及方法
公开(公告)号：US5460629A
公开(公告)日：1995-10-24
申请号：US221975
申请日：1994-04-01
申请人： Leonard M. Shlain , Paul Lubock , Wayne A. Noda
发明人： Leonard M. Shlain , Paul Lubock , Wayne A. Noda
IPC分类号： A61B18/00 , A61B18/14 , A61M1/00 , A61B17/39
CPC分类号： A61B18/1482 , A61B18/1402 , A61B2018/00196 , A61B2018/00976 , A61B2090/0817
摘要： An electrosurgical probe comprises an elongate probe body having a surgical hook at a distal end thereof. A paddle element is reciprocatably mounted within the distal tip of the elongate body so that it can be shifted between an extended position where it covers the hook tip and a retracted position where it leaves the hook tip exposed. The paddle thus can cooperate with the hook in tissue dissection, clean the hook, as well as provide an alternate electrosurgical probe tip for use in electrosurgical procedures.
摘要翻译：电外科探头包括在其远端具有外科钩的细长探针体。桨形元件可往复运动地安装在细长体的远侧末端内，使得其能够在其覆盖钩尖的延伸位置与其离开钩尖露出的缩回位置之间移动。因此，桨可以与组织解剖中的钩配合，清洁钩，以及提供用于电外科程序的替代的电外科探针尖。

96. 发明授权

US09095325B2 Tissue cutting member for a biopsy device 有权
标题翻译：用于活检装置的组织切割构件
公开(公告)号：US09095325B2
公开(公告)日：2015-08-04
申请号：US11438955
申请日：2006-05-22
申请人： Paul Lubock , Frank R. Louw , Richard L. Quick
发明人： Paul Lubock , Frank R. Louw , Richard L. Quick
IPC分类号： A61B10/00 , A61B10/02 , A61B17/32 , A61B17/34
CPC分类号： A61B10/0275 , A61B10/0283 , A61B17/320016 , A61B17/3417
摘要： The invention is directed to tissue cutting members and biopsy devices with such tissue cutting member for separating a tissue specimen from a patient's body at a target site. The tissue cutting member is slidably disposed within an inner lumen of an elongated probe member of the biopsy device to cut a tissue specimen drawn into the interior of an outer cannula of the biopsy device through a tissue receiving aperture in the probe. The tissue cutting member has a tubular distal portion with a distal tip having an outer tissue cutting edge, an inner tissue receiving aperture, and a longitudinally oriented opening with a closed proximal end and open distal end which opens to the inner tissue receiving aperture to facilitate flaring of the distal tubular portion. The cutting member has at least one opening in a wall of the tubular portion to maintain a vacuum during use.
摘要翻译：本发明涉及具有这种组织切割构件的组织切割构件和活检装置，用于在目标部位处将组织标本与患者的身体分离。组织切割构件可滑动地设置在活检装置的细长探针构件的内腔中，以通过探针中的组织接收孔切割拉入活检装置的外套管内部的组织样本。组织切割构件具有管状远端部分，远侧末端具有外部组织切割边缘，内部组织接收孔和纵向定向的开口，其具有封闭的近端和敞开的远端，其通向内部组织接收孔以便于远端管状部分的扩口。切割构件在管状部分的壁中具有至少一个开口，以在使用期间保持真空。

97. 发明授权

US08718745B2 Tissue site markers for in vivo imaging 有权
标题翻译：用于体内成像的组织位点标记
公开(公告)号：US08718745B2
公开(公告)日：2014-05-06
申请号：US12787177
申请日：2010-05-25
申请人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick , Frank R. Louw , Stephen A. DeSantis
发明人： Fred H. Burbank , Paul Lubock , Michael L. Jones , Richard L. Quick , Frank R. Louw , Stephen A. DeSantis
IPC分类号： A61B6/00
CPC分类号： A61B19/54 , A61B6/12 , A61B8/0833 , A61B90/39 , A61B2090/08021 , A61B2090/3908 , A61B2090/3925 , A61B2090/3987 , A61B2090/3991 , A61M37/0069
摘要： An intracorporeal site marker has high ultrasound reflectivity, presents a substantial acoustic signature from a small marker, so as to avoid obscuring diagnostic tissue features in subsequent imaging studies, and can be readily distinguished from biological features. The biopsy site marker may include features to fix the marker to the biopsy site so as to resist migration from the biopsy cavity.
摘要翻译：体内位点标记物具有高超声反射率，从小标记物提供了显着的声学特征，以避免在随后的成像研究中模糊诊断组织特征，并且可以容易地与生物学特征区别开来。活检部位标记可以包括将标记物固定到活检部位以防止从活检腔迁移的特征。

98. 发明授权

US08641640B2 Tissue cutting member for a biopsy device 有权
标题翻译：用于活检装置的组织切割构件
公开(公告)号：US08641640B2
公开(公告)日：2014-02-04
申请号：US11981292
申请日：2007-10-31
申请人： Paul Lubock , Frank R. Louw , Richard L. Quick
发明人： Paul Lubock , Frank R. Louw , Richard L. Quick
IPC分类号： A61B10/00
CPC分类号： A61B10/0275 , A61B10/0283 , A61B17/320016 , A61B17/3417
摘要： The invention is directed to tissue cutting members and biopsy devices with such tissue cutting member for separating a tissue specimen from a patient's body at a target site. The tissue cutting member is slidably disposed within an inner lumen of an elongated probe member of the biopsy device to cut a tissue specimen drawn into the interior of an outer cannula of the biopsy device through a tissue receiving aperture in the probe. The tissue cutting member has a tubular distal portion with a distal tip having an outer tissue cutting edge, an inner tissue receiving aperture, and a longitudinally oriented opening with a closed proximal end and open distal end which opens to the inner tissue receiving aperture to facilitate flaring of the distal tubular portion. The cutting member has at least one opening in a wall of the tubular portion to maintain a vacuum during use.
摘要翻译：本发明涉及具有这种组织切割构件的组织切割构件和活检装置，用于在目标部位处将组织标本与患者的身体分离。组织切割构件可滑动地设置在活检装置的细长探针构件的内腔中，以通过探针中的组织接收孔切割拉入活检装置的外套管内部的组织样本。组织切割构件具有管状远端部分，远侧末端具有外部组织切割边缘，内部组织接收孔和纵向定向的开口，其具有封闭的近端和敞开的远端，其通向内部组织接收孔以便于远端管状部分的扩口。切割构件在管状部分的壁中具有至少一个开口，以在使用期间保持真空。

99. 发明授权

US08636734B2 Tissue specimen isolating and damaging device and method 有权
标题翻译：组织样本分离和破坏装置及方法
公开(公告)号：US08636734B2
公开(公告)日：2014-01-28
申请号：US12082509
申请日：2008-04-11
申请人： Fred H. Burbank , Paul Lubock
发明人： Fred H. Burbank , Paul Lubock
IPC分类号： A61B18/14
CPC分类号： A61B10/0266 , A61B10/0041 , A61B10/02 , A61B10/0233 , A61B17/00234 , A61B17/00491 , A61B17/221 , A61B17/32056 , A61B17/320725 , A61B17/3417 , A61B18/0206 , A61B18/06 , A61B18/14 , A61B18/148 , A61B18/1482 , A61B18/1487 , A61B18/1492 , A61B18/20 , A61B90/37 , A61B2010/0208 , A61B2017/00287 , A61B2017/2212 , A61B2017/320733 , A61B2017/3488 , A61B2018/00208 , A61B2018/00214 , A61B2018/00267 , A61B2018/00333 , A61B2018/00577 , A61B2018/00601 , A61B2018/00898 , A61B2018/0091 , A61B2018/00916 , A61B2018/1253 , A61B2018/126 , A61B2018/1407 , A61B2018/1425 , A61B2018/144 , A61B2018/1475 , A61B2018/162 , A61B2018/1861 , A61B2090/3908 , A61N5/1007 , A61N5/1027
摘要： A device and method for treatment of a tissue specimen disposed in surrounding tissue has a tissue specimen isolating toot and a tissue specimen damager. The tissue specimen isolating tool isolates the tissue specimen from the surrounding tissue. The tissue specimen damager damages the tissue, with a possible end result being necrosis. The severing tool may have a cutting member that is extendable to an outwardly radially bowed position about device. The tissue specimen is isolated by rotating the cutting member about the tissue specimen. The cutting member may be functionally connected to a cutting member radio frequency generation source. The tissue specimen damager may damage the tissue specimen using ionizing radiation, cutting devices, thermal treatment devices, chemical treatment devices, or sealing an outer boundary of the tissue specimen.
摘要翻译：用于处理设置在周围组织中的组织样本的装置和方法具有组织样本分离齿和组织样本容器。组织标本分离工具将组织标本与周围组织隔离。组织标本损伤组织，可能的最终结果是坏死。切割工具可以具有切割构件，该切割构件可延伸到关于装置的向外径向弯曲的位置。通过围绕组织样本旋转切割构件来分离组织样本。切割构件可以功能地连接到切割构件射频发生源。组织样本容器可能会使用电离辐射，切割装置，热处理装置，化学处理装置或密封组织标本的外边界来损伤组织标本。

100. 发明授权

US08361082B2 Marker delivery device with releasable plug 有权
标题翻译：带可释放插头的标记输送装置
公开(公告)号：US08361082B2
公开(公告)日：2013-01-29
申请号：US13037971
申请日：2011-03-01
申请人： Michael L. Jones , Paul Lubock , John Merritt
发明人： Michael L. Jones , Paul Lubock , John Merritt
IPC分类号： A61B17/00
CPC分类号： A61B5/064 , A61B5/055 , A61B5/062 , A61B6/12 , A61B8/0833 , A61B10/02 , A61B17/0057 , A61B90/39 , A61B2017/00637 , A61B2017/00898 , A61B2090/3908 , A61B2090/3925 , A61B2090/3954 , A61B2090/3966 , A61B2090/3987 , A61K49/12 , A61K49/18 , A61K2123/00 , A61M5/007 , A61M37/0069
摘要： A marker delivery device includes an elongated delivery cannula which has a distal end section, an inner lumen and a discharge opening in the distal end section in communication with the inner lumen. At least one elongated fibrous marker body is slidably disposed within the inner lumen of the elongated delivery cannula. The at least one elongated fibrous marker body includes a plurality of bioabsorbable polymeric strands. The strands are compressed to a compressed configuration and bound together in the compressed configuration with a polymer binding agent prior to insertion into the elongated delivery cannula. A releasable plug is disposed within a distal portion of the inner lumen and distal to the at least one elongated fibrous marker body so as to at least partially occlude the discharge opening in the distal end section.
摘要翻译：标记输送装置包括细长的输送套管，其具有与内腔连通的远端部分中的远端部分，内腔和排出口。至少一个细长的纤维标记物体可滑动地设置在细长的输送套管的内腔内。所述至少一个细长的纤维标记物主体包括多个生物可吸收的聚合物链。股线被压缩成压缩构型并且在插入细长的输送套管之前用压缩构型与聚合物粘合剂结合在一起。可释放插塞设置在内腔的远侧部分内并且远离至少一个细长纤维标记体，以至少部分地封闭远端部分中的排出口。

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