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91. 发明公开

EP1394263A1 METHOD OF DETECTING AND SEPARATING UNDIFFERENTIATED LIVER CELLSS USING DLK 有权
标题翻译： VERFAHREN ZUM NACHWEIS UND ZUR TRENNUNG不饱和脂肪酸酯LEBERZELLEN MIT DLK
公开(公告)号：EP1394263A1
公开(公告)日：2004-03-03
申请号：EP02780780.9
申请日：2002-05-16
申请人： KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY , KIRIN BEER KABUSHIKI KAISHA
发明人： TANIMIZU, Naoki , MIYAJIMA, Atsushi
IPC分类号： C12Q1/00 , C12N5/00
CPC分类号： G01N33/56966
摘要： It was discovered that a membrane protein dlk (delta-like) is specifically expressed on the surfaces of fetal hepatic cells. We succeeded in purifying undifferentiated hepatic cells including hepatic stem cells to high purify from mouse fetal liver using an antibody to dlk protein. The obtained fetal hepatic cells included hepatic stem cells having bipotency. The present invention provides a marker molecule of hepatic cells, and a method for detecting undifferentiated hepatic cells utilizing this molecule. The present invention also provides a method for separating undifferentiated hepatic cells utilizing this marker molecule, and the undifferentiated hepatic cells separated by this method. By using the method of the present invention, hepatic stem cells may be purified simply to high concentration. The undifferentiated hepatic cells obtained by the present invention may be used for regenerative medicine and artificial liver. They may also be used for analyses of intercellular interactions, and for assay systems and screening systems for investigating drug metabolism as well as for searching drugs and anti-viral agents which control the drug metabolism or differentiation of hepatic cells.
摘要翻译：已经发现膜蛋白dlk（δ-样）被特异性表达在胎儿肝细胞的表面上。我们使用dlk蛋白的抗体成功地纯化包括肝干细胞在内的未分化肝细胞以从小鼠胎肝中高纯化。获得的胎肝细胞包括具有双性的肝干细胞。本发明提供肝细胞的标记分子，以及利用该分子检测未分化肝细胞的方法。本发明还提供了利用该标记分子分离未分化肝细胞的方法，并且通过该方法分离未分化的肝细胞。通过使用本发明的方法，可以简单地将肝干细胞纯化至高浓度。通过本发明获得的未分化肝细胞可用于再生医学和人造肝。它们还可用于细胞间相互作用的分析，以及用于调查药物代谢的检测系统和筛选系统以及用于搜索控制肝细胞的药物代谢或分化的药物和抗病毒剂。

92. 发明授权

EP1055901B1 Scanning Probe Microscope 有权
标题翻译：扫描探针显微镜
公开(公告)号：EP1055901B1
公开(公告)日：2003-07-23
申请号：EP00110273.0
申请日：2000-05-22
申请人： JASCO CORPORATION , Japan Science and Technology Corporation , KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY
发明人： Narita, Yoshihito , Hisada, Hideho , Miyajima, Tatsuya , Saito, Osamu , Watanabe, Shinichiro , Saito, Shinya , Akutsu, Koji , Teruyama, Susumu , Ohtsu, Motoichi, Kanagawa Academy of Science&Tech.
IPC分类号： G01B7/34 , G02B21/00 , G01N27/00
CPC分类号： G01Q70/12 , G01Q10/02 , G01Q10/06 , G01Q20/02 , G01Q20/04 , G01Q30/06 , G01Q60/22 , G01Q60/34 , G01Q60/38 , G01Q70/02 , Y10S977/851 , Y10S977/872

93. 发明公开

EP1203617A1 Titanium dioxide photo catalyst structure 失效
标题翻译： Titaniumdioxyd-photokatalysatorstruktur
公开(公告)号：EP1203617A1
公开(公告)日：2002-05-08
申请号：EP01127865.2
申请日：1995-10-30
申请人： KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY , NIPPON SODA CO., LTD.
发明人： Fukayama, Shingemichi
IPC分类号： B01J37/02 , B01J21/06
CPC分类号： C03C17/3417 , A61L9/205 , B01J21/06 , B01J21/063 , B01J35/002 , B01J35/004 , B01J37/0244 , C03C17/256 , C03C2217/212 , C03C2217/71 , C03C2218/113 , Y02A50/2327
摘要： The present invention relates to a titanium dioxide photocatalyst structure, a method for producing same and its use for removing carbon dioxide and air pollutants to render indoor space antibacterial.
摘要翻译：本发明涉及一种二氧化钛光催化剂结构体及其制造方法及其除去二氧化碳和空气污染物以使室内空间抗菌的用途。

94. 发明公开

EP0752601A1 OPTICAL FIBER AND ITS MANUFACTURE 失效
标题翻译：光纤及其制造
公开(公告)号：EP0752601A1
公开(公告)日：1997-01-08
申请号：EP94917156.5
申请日：1994-06-03
申请人： KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY
发明人： OHTSU, Motoichi , MONONOBE, Shuji , RAJAGOPALAN, Uma Maheswari
IPC分类号： G02B6/10
CPC分类号： G02B6/4203 , G01Q60/22 , G02B6/241 , G02B6/245 , Y10S977/862 , Y10S977/878
摘要： An optical fiber made up of a core for propagating the light and a clad covering the core for confining the light propagated in the core. The optical fiber has a tapering protrusion at the apex for entrance and exiting of light. The optical fiber is used in a photon scanning tunneling microscope detecting the evanescent light localized in an area smaller in size than the wavelength of light on the surface of a sample as an optical probe disposed in proximity to the surface of the sample for scattering the evanescent light for detecting the scattered light. The optical fiber is optically coupled to an optical waveguide for constituting an optically coupled element. With this optically coupled element, a protrusion of the optical fiber operates as a collection unit for collecting the light propagated in the core. The light collected by the protrusion enters the optical waveguide.
摘要翻译：由用于传播光的芯部和覆盖芯部的包层组成的光纤用于限制在芯部中传播的光。光纤在顶点处具有锥形突起以用于光的入射和出射。将光纤用于光子扫描隧道显微镜，该光子扫描隧道显微镜检测位于比样品表面上的光的波长小的区域中的渐逝光，作为设置在样品表面附近的光学探针用于散射瞬逝用于检测散射光的光。光纤光耦合到用于构成光耦合元件的光波导。利用该光学耦合元件，光纤的突起作为收集单元来收集在芯中传播的光。由突起收集的光进入光波导。

95. 发明公开

EP0699606A1 ELECTROSTATIC LEVITATION CONVEYOR AND ELECTROSTATIC LEVITATION ELECTRODES THEREOF 失效
标题翻译： FÖRDERERMIT ELEKTROSTATISCHER LEVITATION UND SEINE ELEKTRODEN ZUR ELEKTROSTATISCHEN LEVITATION
公开(公告)号：EP0699606A1
公开(公告)日：1996-03-06
申请号：EP95912450.4
申请日：1995-03-17
申请人： THE KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY FOUNDATION , MITSUBISHI MATERIALS CORPORATION
发明人： HIGUCHI, Toshiro , JIN, Ju , KANEMOTO, Manabu Chuo-Kenkyusho Mitsubishi
IPC分类号： B65G54/02 , B65H5/00 , B25J15/06 , H01L21/68
CPC分类号： H01L21/6838 , B65G54/02 , B65H3/18 , B65H5/004 , H01L21/67784 , H01L21/6833 , H02N13/00
摘要： An electrostatic levitation electrode (10) is divided equally into four parts on a disk-like insulating substrate (4) with separation bands (11a, 11b) between them. A positive voltage and a negative voltage are alternately applied to these four fan-shaped electrodes (10a, 10b, 10c, 10d). A round (13) is formed at the corner of each fan-shaped electrodes (10a, 10b, 10c, 10d), and lead wires (12a, 12b, 12c, 12d) are connected to the outer side surfaces of the fan-shaped electrodes (10a, 10b, 10c, 10d), respectively. Accordingly, damage of the electrodes at the lead portions can be eliminated, maximum attraction force and levitation rigidity can be improved, and a levitated body can be correctly conveyed.
摘要翻译：静电悬浮电极（10）在其间具有分离带（11a，11b）的盘形绝缘基板（4）上被均等地分成四部分。对这四个扇形电极（10a，10b，10c，10d）交替施加正电压和负电压。在每个扇形电极（10a，10b，10c，10d）的角部处形成圆形（13），并且引线（12a，12b，12c，12d）连接到扇形电极电极（10a，10b，10c，10d）。因此，可以消除引线部分处的电极损坏，可以提高最大的吸引力和悬浮刚度，并且可以正确地输送悬浮体。

96. 发明授权

EP2045368B8 MOLD, PROCESS FOR MANUFACTURING MOLD, AND PROCESS FOR PRODUCING SHEET 有权转让
标题翻译：模具，制造模具的过程以及生产薄片的过程
公开(公告)号：EP2045368B8
公开(公告)日：2016-12-07
申请号：EP07767794.6
申请日：2007-06-28
申请人： Mitsubishi Rayon Co., Ltd. , KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY
发明人： UOZU, Yoshihiro , OKAMOTO, Eiko , KOJIMA, Katsuhiro , SAKUMA, Satoshi , MASUDA, Hideki , YANAGISHITA, Takashi
IPC分类号： C25D11/12 , B29C33/38 , B29C59/02 , B29C59/04 , C25D11/16 , C25D11/24 , C25D11/04 , C25D1/00 , C25D1/10 , G02B1/118 , B29C35/08
CPC分类号： B29C33/3842 , B29C33/38 , B29C35/0888 , B29C59/046 , B29C2059/023 , C25D1/006 , C25D1/10 , C25D1/20 , C25D11/045 , C25D11/12 , C25D11/16 , G02B1/118

97. 发明公开

EP2671451A1 VIRUS INACTIVATOR 无效
标题翻译：病毒无效者
公开(公告)号：EP2671451A1
公开(公告)日：2013-12-11
申请号：EP10839433.9
申请日：2010-12-22
申请人： The University of Tokyo , Kanagawa Academy Of Science And Technology
发明人： HASHIMOTO, Kazuhito , SUNADA, Kayano , MIYAUCHI, Masahiro , QIU, Xiaoqing , KUBOTA, Yoshinobu , ISHIGURO, Hitoshi , NAKANO, Ryuichi , KAJIOKA, Jitsuo , YAO, Yanyan
IPC分类号： A01N59/20 , A01N59/16 , A01P1/00
CPC分类号： A01N59/20 , A01N25/26 , A01N59/16 , A01N25/04 , A01N25/14
摘要： An agent for virus inactivation capable of exhibiting inactivation action based on structural destruction such as degradation and decomposition against viruses, which comprises a monovalent copper compound such as cuprous oxide, cuprous sulfide, cuprous iodide, and cuprous chloride as an active ingredient, and a virus inactivation material, which contains the agent for virus inactivation on a surface of a substrate and/or inside of the substrate.
摘要翻译：作为有效成分，含有氧化亚铜，硫化亚铜，碘化亚铜，氯化亚铜等一价铜化合物作为有效成分，能够发挥基于病毒的分解，分解等结构破坏的灭活作用的病毒灭活剂，灭活材料，其包含用于在基底表面和/或基底内部病毒灭活的药剂。

98. 发明公开

EP2045368A1 MOLD, PROCESS FOR MANUFACTURING MOLD, AND PROCESS FOR PRODUCING SHEET 有权转让
标题翻译： FORM，用于生产形式，并形成片方法
公开(公告)号：EP2045368A1
公开(公告)日：2009-04-08
申请号：EP07767794.6
申请日：2007-06-28
申请人： Mitsubishi Rayon Co. Ltd. , KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY
发明人： UOZU, Yoshihiro , OKAMOTO, Eiko , KOJIMA, Katsuhiro , SAKUMA, Satoshi c/o Yokohama Research Laboratories, Mitsubishi Rayon Co., Ltd., , MASUDA, Hideki c/o Kanagawa Academy of Science and Technology, , YANAGISHITA, Takashi c/o Kanagawa Academy of Science and Technology,
IPC分类号： C25D11/12 , B29C33/38 , B29C59/02 , B29C59/04 , C25D11/16 , C25D11/24
CPC分类号： B29C33/3842 , B29C33/38 , B29C35/0888 , B29C59/046 , B29C2059/023 , C25D1/006 , C25D1/10 , C25D1/20 , C25D11/045 , C25D11/12 , C25D11/16 , G02B1/118
摘要： A mold comprising alumina having a microscopic pattern, in which distances between adjacent recesses or salients therein are not longer than wavelength of visible light, formed by anodic oxidation on a surface of an alminum pre-mold without a rolling mark, wherein height or depth difference at a crystal grain boundary is 300 nm or less.
摘要翻译：具有微细图案的模具，其包括氧化铝，其中相邻的凹部或salients之间的距离在其中的不大于可见光，通过阳极氧化的Alminum预制模的表面上形成的波长更长的无压延痕迹，worin高度或深度差在晶粒边界是300nm或更小。

99. 发明授权

EP1324024B1 THERMAL LENS MICROSCOPE 有权
标题翻译：与热透镜显微镜装置
公开(公告)号：EP1324024B1
公开(公告)日：2008-06-04
申请号：EP01963525.9
申请日：2001-09-07
申请人： KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY
发明人： Kitamori, Takehiko , Hibara, Akihide , Tokeshi, Manabu
IPC分类号： G01N25/16 , G01N37/00
CPC分类号： G02B21/0008 , G02B6/13 , G02B21/02 , G02B2006/12102

100. 发明公开

EP1816187A1 MICROCHIP 审中-公开
公开(公告)号：EP1816187A1
公开(公告)日：2007-08-08
申请号：EP05806585.5
申请日：2005-11-18
申请人： NISSUI PHARMACEUTICAL CO., LTD. , KANAGAWA ACADEMY OF SCIENCE AND TECHNOLOGY
发明人： Akaba, Shuichi, Nissui Pharmaceutical Co. Ltd. , Oku, Yuichi, Nissui Pharmaceutical Co. Ltd. , Tokeshi, Manabu , KITAMORI, Takehiko
IPC分类号： C12M1/00 , B01J19/00 , B81B1/00 , C12M1/34 , G01N37/00
CPC分类号： B01L3/502761 , B01L2200/0668 , B01L2300/0627 , B01L2300/0825 , B01L2300/0877 , B81B1/002 , B81B2201/058 , G01N33/54366
摘要： A microchip used for a diagnosis device having a micro fluid system, reaction efficiency of which microchip can be drastically increased and which has a flow path realizing measurement with high stability and reproducibility. A microchip in which at least a flow path (12) is formed in interfaces of two substrates and that has, in the flow path (12), a reaction region (14) and a detection region (15) on the downstream side of the reaction region (14). The depth of the flow path (12) in the detection region (15) is greater than the depth of the flow path (12) in the reaction region (14).
摘要翻译：微芯片用于具有微流体系统的诊断装置，其微流体系统的反应效率可以显着增加，并且具有实现高稳定性和再现性的测量的流路。一种微芯片，至少在两个基板的界面形成流路（12），在该流路（12）的下游侧具有反应区域（14）和检测区域（15）反应区（14）。检测区域（15）中的流路（12）的深度大于反应区域（14）中的流路（12）的深度。

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