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1. 发明申请

WO2018109541A1 ALUMINIUM FLUORIDE AND SULFUR FOR THE TREATMENT OF ACNE VULGARIS 审中-公开
公开(公告)号：WO2018109541A1
公开(公告)日：2018-06-21
申请号：PCT/IB2017/000481
申请日：2017-04-07
申请人： MEDIDERMIS LTD.
发明人： DASCALU, Avi
IPC分类号： A61K33/04 , A61K33/16 , A61P17/10
摘要： The present invention is directed to methods and compositions for treatment and reduction of acne vulgaris and related skin disorders, and more specifically, to a composition comprising a combination of aluminum fluoride and sulfur as the sole active agents for the treatment of the acne vulgaris and related skin disorders.

2. 发明申请

WO2007046097A2 TOPICAL COMPOSITIONS FOR THE TREATMENT OF DEPILATION-INDUCED SKIN IRRITATION OR PREVENTION THEREOF 审中-公开
标题翻译：用于治疗诱发性皮肤刺激或预防的主题组合物
公开(公告)号：WO2007046097A2
公开(公告)日：2007-04-26
申请号：PCT/IL2006/001198
申请日：2006-10-18
申请人： MEDIDERMIS LTD. , DASCALU, Avi
发明人： DASCALU, Avi
IPC分类号： H01L31/0264
CPC分类号： A61Q19/00 , A61K8/23 , A61K8/26 , A61K2800/75 , A61Q9/04
摘要： The present invention relates to topical compositions comprising as active ingredients Aluminium Chloride and Sulfur for treatment of skin irritation induced by depilation. Said compositions have pharmaceutical and/or cosmetic and/or quasi cosmetic properties. The present invention also involves methods of making and methods of using such compositions. Furthermore, the present invention consists of a method for prevention and/or treatment of skin irritation induced by depilation.
摘要翻译：本发明涉及包含作为活性成分的氯化铝和硫磺用于治疗由脱毛引起的皮肤刺激的局部组合物。所述组合物具有药物和/或化妆品和/或准化妆品性质。本发明还涉及制备方法和使用这些组合物的方法。此外，本发明包括预防和/或治疗由脱毛引起的皮肤刺激的方法。

3. 发明申请

WO2007046097A3 TOPICAL COMPOSITIONS FOR THE TREATMENT OF DEPILATION-INDUCED SKIN IRRITATION OR PREVENTION THEREOF 审中-公开
标题翻译：用于治疗诱发性皮肤刺激或预防的主题组合物
公开(公告)号：WO2007046097A3
公开(公告)日：2009-04-09
申请号：PCT/IL2006001198
申请日：2006-10-18
申请人： MEDIDERMIS LTD , DASCALU AVI
发明人： DASCALU AVI
IPC分类号： A61K8/19
CPC分类号： A61Q19/00 , A61K8/23 , A61K8/26 , A61K2800/75 , A61Q9/04
摘要： The present invention relates to topical compositions comprising as active ingredients Aluminium Chloride and Sulfur for treatment of skin irritation induced by depilation. Said compositions have pharmaceutical and/or cosmetic and/or quasi cosmetic properties. The present invention also involves methods of making and methods of using such compositions. Furthermore, the present invention consists of a method for prevention and/or treatment of skin irritation induced by depilation.
摘要翻译：本发明涉及包含作为活性成分的氯化铝和硫磺用于治疗由脱毛引起的皮肤刺激的局部组合物。所述组合物具有药物和/或化妆品和/或准化妆品性质。本发明还涉及制备方法和使用这些组合物的方法。此外，本发明包括预防和/或治疗由脱毛引起的皮肤刺激的方法。

4. 发明专利

ES2329987T3 COMPOSICION PARA EL TRATAMIENTO DE INFLAMACIONES DE LAS GLANDULAS PIL OSEBACEAS. 未知
公开(公告)号：ES2329987T3
公开(公告)日：2009-12-03
申请号：ES02775180
申请日：2002-10-02
申请人： MEDIDERMIS LTD
发明人： DASCALU AVI
IPC分类号： A61K33/16 , A61K8/26 , A61K33/06 , A61K45/06 , A61P17/10 , A61Q19/00
摘要： Uso de fluoruro de aluminio o combinaciones de aluminio y sales fluoruro que liberan fluoruro de aluminio para la preparación de composiciones para tratar el acné vulgar y la foliculitis.

5. 发明专利

IL132625A COMPOSITION FOR INDUCING HAIR GROWTH 未知
公开(公告)号：IL132625A
公开(公告)日：2007-06-17
申请号：IL13262599
申请日：1999-10-28
申请人： DASCALU AVI , MEDIDERMIS LTD , AVI DASCXALU
发明人： DASCALU AVI
IPC分类号： A61K8/97 , A61Q7/00

6. 发明专利

PT1478375E COMPOSIÇÕES CONTENDO FLUORETO DE ALUMÍNIO PARA O TRATAMENTO DE INFLAMAÇÕES DA GLÂNDULA PILO-SEBÁCEA 未知
公开(公告)号：PT1478375E
公开(公告)日：2009-12-17
申请号：PT02775180
申请日：2002-10-02
申请人： MEDIDERMIS LTD
发明人： DASCALU AVI
IPC分类号： A61K33/16 , A61K8/26 , A61K33/06 , A61K45/06 , A61P17/10 , A61Q19/00

7. 发明专利

AT440610T 未知
公开(公告)号：AT440610T
公开(公告)日：2009-09-15
申请号：AT02775180
申请日：2002-10-02
申请人： MEDIDERMIS LTD
发明人： DASCALU AVI
IPC分类号： A61K33/16 , A61K8/26 , A61K33/06 , A61K45/06 , A61P17/10 , A61Q19/00
摘要： The present invention relates to compositions for the treatment of pilosebaceous gland inflammations, especially of the hair follicle and its appendages, in particular of Acne Vulgaris and Folliculitis, comprising as active ingredient AIF or chemical compounds which finally release AIF, or combinations of aluminum and fluoride salts which finally release AIF. AIF in accordance with the present invention relates to Aluminum fluoride (Aluminum Trifluoride; Aluminum Fluoride), CAS No 7784-18-1, EINECS No. 232-051-1, having an empirical formula of AIF 3 . Said compositions have, inter alia, pharmaceutical, cosmetic or quasi-cosmetic properties. The present invention also relates to the use of said compositions in said treatment, and to methods for the treatment of pilosebaceous gland inflammations with said compositions.

8. 发明专利

IL145751A USE OF ALUMINUM FLUORIDE FOR THE PREPARATION OF COMPOSITIONS FOR THE TREATMENT OF ACNE VULGARIS AND FOLLICULITIS 未知
公开(公告)号：IL145751A
公开(公告)日：2010-12-30
申请号：IL14575101
申请日：2001-10-04
申请人： DASCALU AVI , MEDIDERMIS LTD , R & DERM LTD
发明人： DASCALU AVI
IPC分类号： A61K8/26 , A61K33/06 , A61K33/16 , A61K45/06 , A61P17/10 , A61Q19/00
摘要： The present invention relates to compositions for the treatment of pilosebaceous gland inflammations, especially of the hair follicle and its appendages, in particular of Acne Vulgaris and Folliculitis, comprising as active ingredient AIF or chemical compounds which finally release AIF, or combinations of aluminum and fluoride salts which finally release AIF. AIF in accordance with the present invention relates to Aluminum fluoride (Aluminum Trifluoride; Aluminum Fluoride), CAS No 7784-18-1, EINECS No. 232-051-1, having an empirical formula of AIF 3 . Said compositions have, inter alia, pharmaceutical, cosmetic or quasi-cosmetic properties. The present invention also relates to the use of said compositions in said treatment, and to methods for the treatment of pilosebaceous gland inflammations with said compositions.

9. 发明专利

DE60233530D1 未知
公开(公告)号：DE60233530D1
公开(公告)日：2009-10-08
申请号：DE60233530
申请日：2002-10-02
申请人： MEDIDERMIS LTD
发明人： DASCALU AVI
IPC分类号： A61K33/16 , A61K8/26 , A61K33/06 , A61K45/06 , A61P17/10 , A61Q19/00
摘要： The present invention relates to compositions for the treatment of pilosebaceous gland inflammations, especially of the hair follicle and its appendages, in particular of Acne Vulgaris and Folliculitis, comprising as active ingredient AIF or chemical compounds which finally release AIF, or combinations of aluminum and fluoride salts which finally release AIF. AIF in accordance with the present invention relates to Aluminum fluoride (Aluminum Trifluoride; Aluminum Fluoride), CAS No 7784-18-1, EINECS No. 232-051-1, having an empirical formula of AIF 3 . Said compositions have, inter alia, pharmaceutical, cosmetic or quasi-cosmetic properties. The present invention also relates to the use of said compositions in said treatment, and to methods for the treatment of pilosebaceous gland inflammations with said compositions.

10. 发明申请

US20070081968A1 AGENT FOR INDUCING HAIR GROWTH CONTAINING EXTRACTS OF SAW PALMETTO AND SWERTIA 有权
标题翻译：用于诱导含有棕榈和斯皮尔的提取物的头发生长的试剂
公开(公告)号：US20070081968A1
公开(公告)日：2007-04-12
申请号：US11608288
申请日：2006-12-08
申请人： Avi Dascalu
发明人： Avi Dascalu
IPC分类号： A61K36/889 , A61K8/97
CPC分类号： A61Q5/006 , A61K8/97 , A61Q7/00
摘要： The present invention consists in a composition comprising a mixture of extracts of saw palmetto and swertia, of derivatives thereof and of active components being part of said extracts. The composition may comprise additional agents and/or extracts, for example, irritating agents, extracts for hair invigoration, hair nourishment agents, antidandruff anti-proliferative compounds, extracts with an antimicrobial, extracts with an antifungal, extracts with anti-inflammatory agents, extracts with a steroid, extracts with a nitric oxide donor and extracts with minoxidil. The concentration of saw palmetto extract in the composition is suitably 0.01-100%. The composition may comprise a suitable carrier, solvent and/or emulgent. The composition may be, for example, an internally ingested tablet, a capsule, drops or a suspension. The invention relates also to the use of said composition in the preparation of a mixture for the application to humans and animals against the loss of hair and to method for the treatment with said composition for the treatment of humans and animals against loss of hair.
摘要翻译：本发明包括一种组合物，其包含锯齿棕榈和挥发油的提取物及其衍生物和作为所述提取物的一部分的活性成分的混合物。组合物可以包含额外的试剂和/或提取物，例如刺激剂，用于头发滋养的提取物，发丝营养剂，去头皮屑抗增殖化合物，具有抗微生物剂的提取物，用抗真菌剂提取物，用抗炎剂提取物，提取物用类固醇，用一氧化氮供体提取，并用米诺地尔提取。组合物中锯棕榈提取物的浓度适宜为0.01-100％。组合物可以包含合适的载体，溶剂和/或渗透剂。组合物可以是例如内部摄取的片剂，胶囊，滴剂或悬浮液。本发明还涉及所述组合物在制备用于人和动物免受毛发损失的混合物的使用以及用于治疗人和动物的所述组合物以防止头发损失的方法。

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