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1. 发明授权

US06178832B2 Reagent pouch for use in a modular automated diagnostic apparatus 有权
标题翻译：用于模块化自动诊断仪器的试剂袋
公开(公告)号：US06178832B2
公开(公告)日：2001-01-30
申请号：US09350054
申请日：1999-07-08
申请人： Vijay Mathur , Tyler Cote , Ronald Jones , Jane Sun , Steve Rettew , Chen Yi , Tony Mao , Will Whelan , Ken Galano , Richard Dussault
发明人： Vijay Mathur , Tyler Cote , Ronald Jones , Jane Sun , Steve Rettew , Chen Yi , Tony Mao , Will Whelan , Ken Galano , Richard Dussault
IPC分类号： G01N100
CPC分类号： G01N35/1002 , G01N35/00712 , G01N35/1095
摘要： A modular automated diagnostic analyzer having a fluid entry module for sample aspiration, a valve module for selecting fluids and a pump module for fluidic movement so that a biological sample does not come into contact with the valve system through which calibrants and air are introduced to the fluid path. The fluid entry module encloses an aspiration tube rotatably and slidably engaged with the analysis mechanism chassis to move to different positions for the introduction of calibration and cleaning fluids and the aspiration of fluids into the analysis apparatus from different types of sample containers. A wiping seal removes residues of aspirated fluids from the exterior surfaces of the aspiration tube with the residue being aspirated into the analysis apparatus for disposal. Sensor modules mounted in a sensor chamber are structured to mechanically stack and interlock and each sensor module includes a fluid tight sealed passage and a sensor element. A fluid selection valve of highly polished ceramic material allows a valve cylinder passage to be selectively connected to fluid sources. A self-contained reagent pouch housing contains calibrants including tonometered calibrants in reagent pouches wherein each pouch wall includes multiple layers of materials wherein at least one layer is a thin, flexible glass material. The walls are extended to form a filler neck sealed by heat and pressure along a sealing line below a filler line so that no bubbles are trapped in the reagent pouch.
摘要翻译：一种模块化自动诊断分析仪，具有用于抽样抽吸的流体输入模块，用于选择流体的阀模块和用于流体运动的泵模块，使得生物样品不与阀系统接触，通过该阀系统将校准物和空气引入到流体路径流体进入模块包围一个抽吸管，该抽吸管与分析机构底盘可旋转地并可滑动地接合，以移动到不同的位置，用于引入校准和清洁流体，以及从不同类型的样品容器将流体抽吸到分析装置中。擦拭密封件从抽吸管的外表面去除吸入流体的残留物，并将残留物吸入分析装置中进行处置。安装在传感器室中的传感器模块被构造成机械地堆叠和互锁，并且每个传感器模块包括流体密封的通道和传感器元件。高度抛光的陶瓷材料的流体选择阀允许阀筒通道选择性地连接到流体源。独立的试剂袋壳体包含在试剂袋中包括计量卡尺的校准物，其中每个袋壁包括多层材料，其中至少一层是薄的柔性玻璃材料。壁被延伸以形成通过加热和压力沿着填充线下方的密封线密封的填充管颈，使得试剂袋中没有气泡被捕获。

2. 发明授权

US06418800B1 Fluid entry mechanism for a modular automated diagnostic apparatus 有权
标题翻译：模块化自动诊断仪的流体输入机构
公开(公告)号：US06418800B1
公开(公告)日：2002-07-16
申请号：US09663719
申请日：2000-09-15
申请人： Vijay Mathur , Tyler Cote , Ronald Jones , Jane Sun , Steve Rettew , Chen Yi , Tony Mao , Will Whelan , Ken Galano , Richard Dussault
发明人： Vijay Mathur , Tyler Cote , Ronald Jones , Jane Sun , Steve Rettew , Chen Yi , Tony Mao , Will Whelan , Ken Galano , Richard Dussault
IPC分类号： G01N100
CPC分类号： G01N35/1002 , G01N35/00712 , G01N35/1095
摘要： A modular automated diagnostic analyzer having a fluid entry module for sample aspiration, a valve module for selecting fluids and a pump module for fluidic movement, so that a biological sample does not come into contact with the valve system through which calibrants and air are introduced to the fluid path. The fluid entry module encloses an aspiration tube rotatably and slidably engaged with the analysis mechanism chassis to move to different positions for the introduction of calibration and cleaning fluids and the aspiration of fluids into the analysis apparatus from different types of sample containers. A wiping seal removes residues of aspirated fluids from the exterior surfaces of the aspiration tube with the residue being aspirated into the analysis apparatus for disposal. Sensor modules mounted in a sensor chamber are structured to mechanically stack and interlock and each sensor module includes a fluid tight sealed passage and a sensor element. A fluid selection valve of highly polished ceramic material allows a valve cylinder passage to be selectively connected to fluid sources. A self-contained reagent pouch housing contains calibrants including tonometered calibrants in reagent pouches wherein each pouch wall includes multiple layers of materials wherein at least one layer is a thin, flexible glass material. The walls are extended to form a filler neck sealed by heat and pressure along a sealing line below a filler line so that no bubbles are trapped in the reagent pouch.
摘要翻译：一种模块化自动诊断分析仪，具有用于样品抽吸的流体入口模块，用于选择流体的阀模块和用于流体运动的泵模块，使得生物样品不与阀系统接触，通过该系统将校准物和空气引入到流体路径。流体进入模块包围一个抽吸管，该抽吸管与分析机构底盘可旋转地并可滑动地接合，以移动到不同的位置，用于引入校准和清洁流体，以及从不同类型的样品容器将流体抽吸到分析装置中。擦拭密封件从抽吸管的外表面去除吸入流体的残留物，并将残留物吸入分析装置中进行处置。安装在传感器室中的传感器模块被构造成机械地堆叠和互锁，并且每个传感器模块包括流体密封的通道和传感器元件。高度抛光的陶瓷材料的流体选择阀允许阀筒通道选择性地连接到流体源。独立的试剂袋壳体包含在试剂袋中包括计量卡尺的校准物，其中每个袋壁包括多层材料，其中至少一层是薄的柔性玻璃材料。壁被延伸以形成通过加热和压力沿着填充线下方的密封线密封的填充管颈，使得试剂袋中没有气泡被捕获。

3. 发明授权

US06293162B1 Fluid selection valve for a modular automated diagnostic apparatus 失效
标题翻译：用于模块化自动诊断仪的流体选择阀
公开(公告)号：US06293162B1
公开(公告)日：2001-09-25
申请号：US09350247
申请日：1999-07-08
申请人： Vijay Mathur , Tyler Cote , Ronald Jones , Jane Sun , Steve Rettew , Chen Yi , Tony Mao , Will Whelan , Ken Galano , Richard Dussault
发明人： Vijay Mathur , Tyler Cote , Ronald Jones , Jane Sun , Steve Rettew , Chen Yi , Tony Mao , Will Whelan , Ken Galano , Richard Dussault
IPC分类号： G01N100
CPC分类号： G01N35/1002 , G01N35/00712 , G01N35/1095
摘要： A modular automated diagnostic analyzer having a fluid entry module for sample aspiration, a valve module for selecting fluids and a pump module for fluidic movement, so that a biological sample does not come into contact with the valve system through which calibrants and air are introduced to the fluid path. The fluid entry module encloses an aspiration tube rotatably and slidably engaged with the analysis mechanism chassis to move to different positions for the introduction of calibration and cleaning fluids and the aspiration of fluids into the analysis apparatus from different tpes of sample containers. A wiping seal removes residues of aspirated fluids from the exterior surfaces of the aspiration tube with the residue being aspirated into the analysis apparatus for disposal. Sensor modules mounted in a sensor chamber are structured to mechanically stack and interlock and each sensor module includes a fluid tight sealed passage and a sensor element. A fluid selection valve of highly polished ceramic material allows a valve cylinder passage to be selectively connected to fluid sources. A self-contained reagent pouch housing contains calibrants including tonometered calibrants in reagent pouches wherein each pouch wall includes multiple layers of materials wherein at least one layer is a thin, flexible glass material. The walls are extended to form a filler neck sealed by heat and pressure along a sealing line below a filler line so that no bubbles are trapped in the reagent pouch.
摘要翻译：一种模块化自动诊断分析仪，具有用于样品抽吸的流体入口模块，用于选择流体的阀模块和用于流体运动的泵模块，使得生物样品不与阀系统接触，通过该系统将校准物和空气引入到流体路径。流体进入模块将抽吸管与分析机构底座可旋转地并可滑动地接合以移动到不同的位置，以引入校准和清洁流体，以及从不同的样品容器的抽吸将流体抽入分析装置。擦拭密封件从抽吸管的外表面去除吸入流体的残留物，并将残留物吸入分析装置中进行处置。安装在传感器室中的传感器模块被构造成机械地堆叠和互锁，并且每个传感器模块包括流体密封的通道和传感器元件。高度抛光的陶瓷材料的流体选择阀允许阀筒通道选择性地连接到流体源。独立的试剂袋壳体包含在试剂袋中包括计量卡尺的校准物，其中每个袋壁包括多层材料，其中至少一层是薄的柔性玻璃材料。壁被延伸以形成通过加热和压力沿着填充线下方的密封线密封的填充管颈，使得试剂袋中没有气泡被捕获。

4. 发明授权

US06289751B1 Modular sensor system for a modular automated diagnostic apparatus 有权
标题翻译：用于模块化自动诊断仪的模块化传感器系统
公开(公告)号：US06289751B1
公开(公告)日：2001-09-18
申请号：US09350055
申请日：1999-07-08
申请人： Vijay Mathur , Tyler Cote , Ronald Jones , Jane Sun , Steve Rettew , Chen Yi , Tony Mao , Will Whelan , Ken Galano , Richard Dussault
发明人： Vijay Mathur , Tyler Cote , Ronald Jones , Jane Sun , Steve Rettew , Chen Yi , Tony Mao , Will Whelan , Ken Galano , Richard Dussault
IPC分类号： G01N100
CPC分类号： G01N35/1002 , G01N35/00712 , G01N35/1095
摘要： A modular automated diagnostic analyzer having a fluid entry module for sample aspiration, a valve module for selecting fluids and a pump module for fluidic movement. so that a biological sample does not come into contact with the valve system through which calibrants and air are introduced to the fluid path. The fluid entry module encloses an aspiration tube rotatably and slidably engaged with the analysis mechanism chassis to move to different positions for the introduction of calibration and cleaning fluids and the aspiration of fluids into the analysis apparatus from different types of sample containers. A wiping seal removes residues of aspirated fluids from the exterior surfaces of the aspiration tube with the residue being aspirated into the analysis apparatus for disposal. Sensor modules mounted in a sensor chamber are structured to mechanically stack and interlock and each sensor module includes a fluid tight sealed passage and a sensor element. A fluid selection valve of highly polished ceramic material allows a valve cylinder passage to be selectively connected to fluid sources. A self-contained reagent pouch housing contains calibrants including tonometered calibrants in reagent pouches wherein each pouch wall includes multiple layers of materials wherein at least one layer is a thin, flexible glass material. The walls are extended to form a filler neck sealed by heat and pressure along a sealing line below a filler line so that no bubbles are trapped in the reagent pouch.
摘要翻译：一种模块化自动诊断分析仪，具有用于样品抽吸的流体进入模块，用于选择流体的阀模块和用于流体运动的泵模块。使得生物样品不与阀系统接触，通过该系统将校准物和空气引入流体路径。流体进入模块包围一个抽吸管，该抽吸管与分析机构底盘可旋转地并可滑动地接合，以移动到不同的位置，用于引入校准和清洁流体，以及从不同类型的样品容器将流体抽吸到分析装置中。擦拭密封件从抽吸管的外表面去除吸入流体的残留物，并将残留物吸入分析装置中进行处置。安装在传感器室中的传感器模块被构造成机械地堆叠和互锁，并且每个传感器模块包括流体密封的通道和传感器元件。高度抛光的陶瓷材料的流体选择阀允许阀筒通道选择性地连接到流体源。独立的试剂袋壳体包含在试剂袋中包括计量卡尺的校准物，其中每个袋壁包括多层材料，其中至少一层是薄的柔性玻璃材料。壁被延伸以形成通过加热和压力沿着填充线下方的密封线密封的填充管颈，使得试剂袋中没有气泡被捕获。

5. 发明申请

US20050145020A1 Modular film sensors with record memory for a modular automated diagnostic apparatus 有权
标题翻译：具有记录存储器的模块化电影传感器，用于模块化自动诊断设备
公开(公告)号：US20050145020A1
公开(公告)日：2005-07-07
申请号：US11053277
申请日：2005-02-08
申请人： Vijay Mathur , Tyler Cote , Ronald Jones , Jane Sun , Steve Rettew , Chen Yi , Tony Mao , Will Whelan , Ken Galano , Richard Dussault
发明人： Vijay Mathur , Tyler Cote , Ronald Jones , Jane Sun , Steve Rettew , Chen Yi , Tony Mao , Will Whelan , Ken Galano , Richard Dussault
IPC分类号： G01N1/00 , G01N35/00 , G01N35/10 , G01N27/416 , G01N33/487
CPC分类号： G01N35/1002 , G01N35/00712 , G01N35/1095 , G01N2035/00683
摘要： A modular automated diagnostic analyzer having a fluid entry module for sample aspiration, a valve module for selecting fluids and a pump module for fluidic movement so that a biological samples does not come into contact with the valve system through which calibrants and air are introduced to the fluid path. The fluid entry module encloses an aspiration tube rotatably and slidably engaged with the analysis mechanism chassis to move to different positions for the introduction of fluids into the analysis apparatus from different types of sample containers. A wiping seal removes residues of aspirated fluids from the exterior surfaces of the aspiration tube with the residue being aspirated into the analysis apparatus for disposal. Sensor modules mounted in a sensors chamber are structured to mechanically stack and interlock and include film sensors with use life record memories and each sensor module includes a fluid tight sealed passage and a sensor element. A fluid selection valve of highly polished ceramic material allows a valve cylinder passage to be selectively connected to fluid sources. A self-contained reagent pouch housing contains calibrants including tonometered calibrants in reagent pouches wherein each pouch wall includes multiple layers of materials wherein at least one layer is a thin, flexible glass material. The walls are extended to form a filler neck sealed by heat and pressure along a sealing line below a filler line so that no bubbles are trapped in the reagent pouch.
摘要翻译：一种模块化自动诊断分析仪，具有用于抽样抽吸的流体进入模块，用于选择流体的阀模块和用于流体运动的泵模块，使得生物样品不与阀系统接触，通过该系统将校准物和空气引入到流体路径流体进入模块包围一个抽吸管，该抽吸管与分析机构底盘可旋转地并可滑动地接合，以移动到不同的位置，以便从不同类型的样品容器将流体引入分析装置。擦拭密封件从抽吸管的外表面去除吸入流体的残留物，并将残留物吸入分析装置中进行处置。安装在传感器室中的传感器模块被构造成机械地堆叠和互锁并且包括具有使用寿命记录存储器的膜传感器，并且每个传感器模块包括流体密封的通道和传感器元件。高度抛光的陶瓷材料的流体选择阀允许阀筒通道选择性地连接到流体源。独立的试剂袋壳体包含在试剂袋中包括计量卡尺的校准物，其中每个袋壁包括多层材料，其中至少一层是薄的柔性玻璃材料。壁被延伸以形成通过加热和压力沿着填充线下方的密封线密封的填充管颈，使得试剂袋中没有气泡被捕获。

6. 发明授权

US06886421B2 Modular film sensors with record memory for modular automated diagnostic apparatus 失效
标题翻译：具有记录存储器的模块化电影传感器，用于模块化自动诊断设备
公开(公告)号：US06886421B2
公开(公告)日：2005-05-03
申请号：US10045464
申请日：2001-11-08
申请人： Vijay Mathur , Tyler Cote , Ronald Jones , Jane Sun , Steve Rettew , Chen Yi , Tony Mao , Will Whelan , Ken Galano , Richard Dussault
发明人： Vijay Mathur , Tyler Cote , Ronald Jones , Jane Sun , Steve Rettew , Chen Yi , Tony Mao , Will Whelan , Ken Galano , Richard Dussault
IPC分类号： G01N1/00 , G01N35/00 , G01N35/10
CPC分类号： G01N35/1002 , G01N35/00712 , G01N35/1095 , G01N2035/00683
摘要： A modular automated diagnostic analyzer having a fluid entry module for sample aspiration, a valve module for selecting fluids and a pump module for fluidic movement so that a biological sample does not come into contact with the valve system through which calibrants and air are introduced to the fluid path. The fluid entry module encloses an aspiration tube rotatably and slidably engaged with the analysis mechanism chassis to move to different positions for the introduction of fluids into the analysis apparatus from different types of sample containers. A wiping seal removes residues of aspirated fluids from the exterior surfaces of the aspiration tube with the residue being aspirated into the analysis apparatus for disposal. Sensor modules mounted in a sensor chamber are structured to mechanically stack and interlock and include film sensors with use life record memories and each sensor module includes a fluid tight sealed passage and a sensor element. A fluid selection valve of highly polished ceramic material allows a valve cylinder passage to be selectively connected to fluid sources. A self-contained reagent pouch housing contains calibrants including tonometered calibrants in reagent pouches wherein each pouch wall includes multiple layers of materials wherein at least one layer is a thin, flexible glass material. The walls are extended to form a filler neck sealed by heat and pressure along a sealing line below a filler line so that no bubbles are trapped in the reagent pouch.
摘要翻译：一种模块化自动诊断分析仪，具有用于抽样抽吸的流体输入模块，用于选择流体的阀模块和用于流体运动的泵模块，使得生物样品不与阀系统接触，通过该系统将校准物和空气引入到流体路径流体进入模块包围一个抽吸管，该抽吸管与分析机构底盘可旋转地并可滑动地接合，以移动到不同的位置，以便从不同类型的样品容器将流体引入分析装置。擦拭密封件从抽吸管的外表面去除吸入流体的残留物，并将残留物吸入分析装置中进行处置。安装在传感器室中的传感器模块被构造成机械地堆叠和互锁并且包括使用寿命记录存储器的膜传感器，并且每个传感器模块包括流体密封的通道和传感器元件。高度抛光的陶瓷材料的流体选择阀允许阀筒通道选择性地连接到流体源。独立的试剂袋壳体包含在试剂袋中包括计量卡尺的校准物，其中每个袋壁包括多层材料，其中至少一层是薄的柔性玻璃材料。壁被延伸以形成通过加热和压力沿着填充线下方的密封线密封的填充管颈，使得试剂袋中没有气泡被捕获。

7. 发明授权

US07127957B2 Modular film sensors with record memory for a modular automated diagnostic apparatus 有权
标题翻译：具有记录存储器的模块化电影传感器，用于模块化自动诊断设备
公开(公告)号：US07127957B2
公开(公告)日：2006-10-31
申请号：US11053277
申请日：2005-02-08
申请人： Vijay Mathur , Tyler Cote , Ronald Jones , Jane Sun , Steve Rettew , Chen Yi , Tony Mao , Will Whelan , Ken Galano , Richard Dussault
发明人： Vijay Mathur , Tyler Cote , Ronald Jones , Jane Sun , Steve Rettew , Chen Yi , Tony Mao , Will Whelan , Ken Galano , Richard Dussault
IPC分类号： G01N1/00
CPC分类号： G01N35/1002 , G01N35/00712 , G01N35/1095 , G01N2035/00683
摘要： A modular automated diagnostic analyzer having a fluid entry module for sample aspiration, a valve module for selecting fluids and a pump module for fluidic movement so that a biological samples does not come into contact with the valve system through which calibrants and air are introduced to the fluid path. The fluid entry module encloses an aspiration tube rotatably and slidably engaged with the analysis mechanism chassis to move to different positions for the introduction of fluids into the analysis apparatus from different types of sample containers. A wiping seal removes residues of aspirated fluids from the exterior surfaces of the aspiration tube with the residue being aspirated into the analysis apparatus for disposal. Sensor modules mounted in a sensors chamber are structured to mechanically stack and interlock and include film sensors with use life record memories and each sensor module includes a fluid tight sealed passage and a sensor element. A fluid selection valve of highly polished ceramic material allows a valve cylinder passage to be selectively connected to fluid sources. A self-contained reagent pouch housing contains calibrants including tonometered calibrants in reagent pouches wherein each pouch wall includes multiple layers of materials wherein at least one layer is a thin, flexible glass material. The walls are extended to form a filler neck sealed by heat and pressure along a sealing line below a filler line so that no bubbles are trapped in the reagent pouch.
摘要翻译：一种模块化自动诊断分析仪，具有用于抽样抽吸的流体进入模块，用于选择流体的阀模块和用于流体运动的泵模块，使得生物样品不与阀系统接触，通过该系统将校准物和空气引入到流体路径流体进入模块包围一个抽吸管，该抽吸管与分析机构底盘可旋转地并可滑动地接合，以移动到不同的位置，以便从不同类型的样品容器将流体引入分析装置。擦拭密封件从抽吸管的外表面去除吸入流体的残留物，并将残留物吸入分析装置中进行处置。安装在传感器室中的传感器模块被构造成机械地堆叠和互锁并且包括具有使用寿命记录存储器的膜传感器，并且每个传感器模块包括流体密封的通道和传感器元件。高度抛光的陶瓷材料的流体选择阀允许阀筒通道选择性地连接到流体源。独立的试剂袋壳体包含在试剂袋中包括计量卡尺的校准物，其中每个袋壁包括多层材料，其中至少一层是薄的柔性玻璃材料。壁被延伸以形成通过加热和压力沿着填充线下方的密封线密封的填充管颈，使得试剂袋中没有气泡被捕获。

8. 发明授权

US5983734A Modular automated diagnostic analysis apparatus with a self cleaning sample input port, an improved fluid selection port, and an improved reagent pack 失效
标题翻译：具有自清洁样品输入端口，改进的流体选择端口和改进的试剂盒的模块化自动诊断分析装置
公开(公告)号：US5983734A
公开(公告)日：1999-11-16
申请号：US118683
申请日：1998-06-30
申请人： Vijay Mathur , Tyler Cote , Ronald Jones , Jane Sun , Steve Rettew , Chen Yi , Tony Mao , Will Whelan , Ken Galano , Richard Dussault
发明人： Vijay Mathur , Tyler Cote , Ronald Jones , Jane Sun , Steve Rettew , Chen Yi , Tony Mao , Will Whelan , Ken Galano , Richard Dussault
IPC分类号： G01N1/00 , G01N35/00 , G01N35/10
CPC分类号： G01N35/1002 , G01N35/00712 , G01N35/1095
摘要： A modular automated diagnostic analyzer having a fluid entry module for sample aspiration, a valve module for selecting fluids and a pump module for fluidic movement so that a biological sample does not come into contact with the valve system through which calibrants and air are introduced to the fluid path. The fluid entry module encloses an aspiration tube rotatably and slidably engaged with the analysis mechanism chassis to move to different positions for the introduction of calibration and cleaning fluids and the aspiration of fluids into the analysis apparatus from a different types of sample containers. A wiping seal removes residues of aspirated fluids from the exterior surfaces of the aspiration tube with the residue being aspirated into the analysis apparatus for disposal. Sensor modules mounted in a sensor chamber are structured to mechanically stack and interlock and each sensor module includes a fluid tight sealed passage and a sensor element. An fluid selection valve of highly polished ceramic material allows a valve cylinder passage to be selectively connected to fluid sources. A self-contained reagent pack contains calibrants including tonometered calibrants in reagent pouches wherein each pouch wall includes multiple layers of materials wherein at least one layer is a thin, flexible glass material. The walls are extended to form a filler neck sealed by heat and pressure along a sealing line below a filler line so that no bubbles are trapped in the reagent pouch.
摘要翻译：一种模块化自动诊断分析仪，具有用于抽样抽吸的流体输入模块，用于选择流体的阀模块和用于流体运动的泵模块，使得生物样品不与阀系统接触，通过该阀系统将校准物和空气引入到流体路径流体进入模块包围一个抽吸管，该抽吸管与分析机构底盘可旋转地并可滑动地接合，以移动到不同的位置，用于引入校准和清洁流体，以及从不同类型的样品容器将流体抽吸到分析装置中。擦拭密封件从抽吸管的外表面去除吸入流体的残留物，并将残留物吸入分析装置中进行处置。安装在传感器室中的传感器模块被构造成机械地堆叠和互锁，并且每个传感器模块包括流体密封的通道和传感器元件。高度抛光的陶瓷材料的流体选择阀允许阀芯通道选择性地连接到流体源。独立的试剂盒包含在试剂袋中包括计量校准物的校准物，其中每个袋壁包括多层材料，其中至少一层是薄的柔性玻璃材料。壁被延伸以形成通过加热和压力沿着填充线下方的密封线密封的填充管颈，使得试剂袋中没有气泡被捕获。

9. 发明申请

US20170328924A1 Automated microscopic cell analysis 审中-公开
公开(公告)号：US20170328924A1
公开(公告)日：2017-11-16
申请号：US14947971
申请日：2015-11-20
申请人： Ronald Jones , Adrian Gropper , Robert Hagopian , Charles Rogers , Thomas Vitella , Tyler Cote , Donald Barry , Dirk Osterloh , Chen Yi
发明人： Ronald Jones , Adrian Gropper , Robert Hagopian , Charles Rogers , Thomas Vitella , Tyler Cote , Donald Barry , Dirk Osterloh , Chen Yi
IPC分类号： G01N35/00 , B01L3/00 , G02B21/16 , G01N1/31 , G01N35/10 , G02B21/34 , G01N15/14 , G01N15/00 , G01N15/10
CPC分类号： G02B21/16 , B01L3/502715 , B01L9/527 , B01L2200/04 , B01L2200/0605 , B01L2200/0684 , B01L2200/0689 , B01L2200/16 , B01L2300/021 , B01L2300/0654 , B01L2300/0867 , B01L2300/0883 , B01L2300/123 , B01L2300/161 , B01L2400/049 , B01L2400/0622 , B01L2400/0644 , B01L2400/0694 , G01N1/312 , G01N1/38 , G01N15/1463 , G01N35/00069 , G01N2015/0073 , G01N2015/008 , G01N2015/1006 , G01N2015/1486 , G01N2035/00138 , G02B21/34
摘要： Disclosed in one aspect is a method for performing a complete blood count (CBC) on a sample of whole blood by metering a predetermined amount of the whole blood and mixing it with a predetermined amount of diluent and stain and transferring a portion thereof to an imaging chamber of fixed dimensions and utilizing an automated microscope with digital camera and cell counting and recognition software to count every white blood cell and red blood corpuscle and platelet in the sample diluent/stain mixture to determine the number of red cells, white cells, and platelets per unit volume, and analyzing the white cells with cell recognition software to classify them.

10. 发明申请

US20170326549A1 AUTOMATED MICROSCOPIC CELL ANALYSIS 审中-公开
公开(公告)号：US20170326549A1
公开(公告)日：2017-11-16
申请号：US15017498
申请日：2016-02-05
申请人： Ronald Jones , Adrian Gropper , Charles Rogers , Thomas Vitella , Donald Barry , Dirk Osterloh , Chen Yi , Tyler Cote
发明人： Ronald Jones , Adrian Gropper , Charles Rogers , Thomas Vitella , Donald Barry , Dirk Osterloh , Chen Yi , Tyler Cote
IPC分类号： B01L3/00 , G01N15/14 , G01N15/10
CPC分类号： G06K9/00134 , B01L3/502715 , B01L3/502738 , B01L2200/027 , B01L2200/0605 , B01L2200/0647 , B01L2200/16 , B01L2300/0627 , B01L2400/0633 , B01L2400/0644 , G01N1/10 , G01N1/30 , G01N15/1434 , G01N15/1463 , G01N15/1484 , G01N21/05 , G01N33/487 , G01N33/49 , G01N33/4915 , G01N33/5094 , G01N33/80 , G01N2015/0065 , G01N2015/008 , G01N2015/0084 , G01N2015/1006 , G01N2015/1486 , G01N2035/00148 , G06K9/00147 , Y10T436/101666
摘要： This disclosure describes single-use test cartridges, cell analyzer apparatus, and methods for automatically performing microscopic cell analysis tasks, such as counting blood cells in biological samples. A small unmeasured quantity of a biological sample such as whole blood is placed in the disposable test cartridge which is then inserted into the cell analyzer. The analyzer isolates a precise volume of the biological sample, mixes it with self-contained reagents and transfers the entire volume to an imaging chamber. The geometry of the imaging chamber is chosen to maintain the uniformity of the mixture, and to prevent cells from crowding or clumping, when it is transferred into the imaging chamber. Images of essentially all of the cellular components within the imaging chamber are analyzed to obtain counts per unit volume. The devices, apparatus and methods described may be used to analyze a small quantity of whole blood to obtain counts per unit volume of red blood cells, white blood cells, including sub-groups of white cells, platelets and measurements related to these bodies.

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