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1. 发明专利

DE60220815D1 未知
公开(公告)号：DE60220815D1
公开(公告)日：2007-08-02
申请号：DE60220815
申请日：2002-11-04
申请人： UNIV STRATHCLYDE GLASGOW , UNIV GLASGOW
发明人： SMITH WILLIAM EWEN , GRAHAM DUNCAN , COOPER JONATHAN MARK , KEIR RUTH , IGATA EISHI
IPC分类号： G01N21/65 , G01N33/58 , C12M1/00 , C12M1/34 , C12N15/09 , C12Q1/02 , C12Q1/68 , G01J3/44 , G01N33/48 , G01N33/483
摘要： The present invention relates to a microfluidic method of generating in situ a colloid for use in detecting an analyte using for example SER(R)S, as well as a method of detecting an analyte using SER(R)S in a microfluidic system. The invention also relates to microfluidic devices for use in detecting analytes such as by way of SER(R)S signals.

2. 发明专利

DE69800786T2 未知
公开(公告)号：DE69800786T2
公开(公告)日：2001-09-13
申请号：DE69800786
申请日：1998-07-08
申请人： CIBA SC HOLDING AG , UNIV STRATHCLYDE GLASGOW
发明人： CHISHOLM GREIG , SMITH WILLIAM EWEN , WHITE PETE CYRIL
IPC分类号： G01N21/65 , C08K3/00 , C08K5/00 , C08L101/00 , C09B67/22
摘要： A plastics material which contains a pigment composition comprising a pigment having adsorbed on its surface, or as a physical mixture, up to 10% by weight, based on the total weight of pigment composition of a coding compound which is a compound containing azo, azomethine or polycyclic chromophore and which has an absorption spectrum and a Raman spectrum different from that of the pigment.

3. 发明专利

DE60220815T2 未知
公开(公告)号：DE60220815T2
公开(公告)日：2008-03-06
申请号：DE60220815
申请日：2002-11-04
申请人： UNIV STRATHCLYDE GLASGOW , UNIV GLASGOW
发明人： SMITH WILLIAM EWEN , GRAHAM DUNCAN , COOPER JONATHAN MARK , KEIR RUTH , IGATA EISHI
IPC分类号： G01N21/65 , G01N33/58 , C12M1/00 , C12M1/34 , C12N15/09 , C12Q1/02 , C12Q1/68 , G01J3/44 , G01N33/48 , G01N33/483
摘要： The present invention relates to a microfluidic method of generating in situ a colloid for use in detecting an analyte using for example SER(R)S, as well as a method of detecting an analyte using SER(R)S in a microfluidic system. The invention also relates to microfluidic devices for use in detecting analytes such as by way of SER(R)S signals.

4. 发明专利

DE69941688D1 未知
公开(公告)号：DE69941688D1
公开(公告)日：2010-01-07
申请号：DE69941688
申请日：1999-02-26
申请人： UNIV STRATHCLYDE GLASGOW
发明人： WHITE PETER CYRIL , ATHMANI SALAH , SMITH WILLIAM EWEN , SADLER DARAN ANTONY
IPC分类号： G01N33/543 , G01N33/58 , G01N33/94
摘要： Immunoassay displacement methods for detecting (preferably identifying) the presence or amount of a target analyte (e.g. drug) in a sample comprising the steps of: (a) exposing the sample to a complex comprising an immobilized antibody capable of specifically binding the analyte, said antibody being specifically bound to a displacement agent, wherein said agent comprises: (I) an analyte analog capable of specifically binding the antibody, (ii) a surface enhanced resonance raman scattering (SERRS) or a surface enhanced raman scattering (SERS) active label, (iii) a SERRS or SERS surface-seeking group (e.g. benztriazole), whereby any analyte present in the sample causes the displacement of agent from the antibody; (b) exposing any displaced agent to a SERRS or SERS surface; and, (c) detecting any displaced agent associated with said surface using SERRS or SERS. In preferred forms of the invention several target analytes are detected from a single source or sample simultaneously. Also provided are agents per se e.g. for use in drug or explosive detection. These may include chromophores and linking groups.

5. 发明专利

DE60135839D1 未知
公开(公告)号：DE60135839D1
公开(公告)日：2008-10-30
申请号：DE60135839
申请日：2001-04-09
申请人： UNIV STRATHCLYDE GLASGOW
发明人： SMITH WILLIAM EWEN , GRAHAM DUNCAN , MCHUGH CALLUM JOHN , KEIR RUTH LYNDSEY , WHITE PETER CYRIL , CAMPBELL MAIRI
IPC分类号： G01N21/65 , C07D213/53 , C07D213/79 , C07D215/38 , C07D249/18 , C07D333/12 , C07D403/04 , C07D487/08 , C07D487/18 , G01N33/543
摘要： The present invention relates to sensitive SE(R)RS based methods for detecting analytes such as explosives and drugs, which may be present in a sample at extremely low levels. The methods may be generally carried out in situ employing novel chemistry which is compatible with flow-cell technology and with time-scales and concentrations required for rapid and informative screening of large numbers of samples. The present invention also relates to novel compounds e.g. synthons and apparatus for use with the methods disclosed.

6. 发明专利

DE69721855T2 未知
公开(公告)号：DE69721855T2
公开(公告)日：2003-10-09
申请号：DE69721855
申请日：1997-01-17
申请人： CIBA SC HOLDING AG , UNIV STRATHCLYDE GLASGOW
发明人： MACPHERSON IAN ALEXANDER , FRASER IAIN FRANK , WHITE PETER CYRIL , SMITH WILLIAM EWEN
IPC分类号： B42D15/00 , B41M3/14 , C09B67/20 , C09B67/22 , C09D11/00 , G01N21/25 , C09B67/08
摘要： The invention provides a pigment composition comprising a pigment having adsorbed on its surface, or as a physical mixture, up to 10% by weight, based on the total weight of pigment composition of a coding compound which is a compound containing an azo, azomethine or polycyclic chromophore and which has an absorption spectrum and a Raman spectrum different from that of the pigment. The compositions are suitable for use in printing inks for security applications.

7. 发明专利

DE69721855D1 未知
公开(公告)号：DE69721855D1
公开(公告)日：2003-06-18
申请号：DE69721855
申请日：1997-01-17
申请人： CIBA SC HOLDING AG , UNIV STRATHCLYDE GLASGOW
发明人： MACPHERSON IAN ALEXANDER , FRASER IAIN FRANK , WHITE PETER CYRIL , SMITH WILLIAM EWEN
IPC分类号： B42D15/00 , B41M3/14 , C09B67/20 , C09B67/22 , C09D11/00 , G01N21/25 , C09B67/08
摘要： The invention provides a pigment composition comprising a pigment having adsorbed on its surface, or as a physical mixture, up to 10% by weight, based on the total weight of pigment composition of a coding compound which is a compound containing an azo, azomethine or polycyclic chromophore and which has an absorption spectrum and a Raman spectrum different from that of the pigment. The compositions are suitable for use in printing inks for security applications.

8. 发明专利

DE69800786D1 未知
公开(公告)号：DE69800786D1
公开(公告)日：2001-06-21
申请号：DE69800786
申请日：1998-07-08
申请人： CIBA SC HOLDING AG , UNIV STRATHCLYDE GLASGOW
发明人： CHISHOLM GREIG , SMITH WILLIAM EWEN , WHITE PETE CYRIL
IPC分类号： G01N21/65 , C08K3/00 , C08K5/00 , C08L101/00 , C09B67/22
摘要： A plastics material which contains a pigment composition comprising a pigment having adsorbed on its surface, or as a physical mixture, up to 10% by weight, based on the total weight of pigment composition of a coding compound which is a compound containing azo, azomethine or polycyclic chromophore and which has an absorption spectrum and a Raman spectrum different from that of the pigment.

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