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1. 发明申请

US20110295141A1 METHODS AND SYSTEMS FOR ENDOBRONCHIAL DIAGNOSTICS 审中-公开
标题翻译：内分泌诊断的方法与系统
公开(公告)号：US20110295141A1
公开(公告)日：2011-12-01
申请号：US12954499
申请日：2010-11-24
申请人： Srikanth Radhakrishnan , Ryan Olivera , Niyazi Beyhan , Surag Mantri , Lutz Freitag
发明人： Srikanth Radhakrishnan , Ryan Olivera , Niyazi Beyhan , Surag Mantri , Lutz Freitag
IPC分类号： A61B5/08
CPC分类号： A61B5/082
摘要： A method for assessing lung function in a patient is disclosed. The method comprises isolating a lung compartment. Thereafter, in one embodiment, an inhaled gas of known composition is introduced into the lung and compared to the composition of the exhaled gas. Alternatively, accumulated CO2 content is measured within the isolated lung compartment over time, and compared to a baseline CO2 content. Alternatively, a change in pressure of an isolated lung compartment may be monitored. Alternatively, the magnitude of the range of CO2 values in an isolated lung compartment can be compared to a predetermined threshold. Any of the results obtained via these alternative embodiments may be used to determine lung function.
摘要翻译：公开了一种用于评估患者的肺功能的方法。该方法包括分离肺隔室。此后，在一个实施方案中，将已知组合物的吸入气体引入肺中并与呼出气体的组成进行比较。或者，随着时间的推移在隔离的肺隔室内测量累积的CO 2含量，并与基线CO 2含量进行比较。或者，可以监测隔离的肺隔室的压力变化。或者，可以将隔离的肺隔室中的CO 2值的范围的大小与预定阈值进行比较。通过这些替代实施方案获得的任何结果可用于确定肺功能。

2. 发明申请

US20110251509A1 SYSTEMS AND METHODS FOR INHIBITING SECRETION FLOW INTO A FUNCTIONAL ASSESSMENT CATHETER 审中-公开
标题翻译：用于抑制分泌流入功能评估导管的系统和方法
公开(公告)号：US20110251509A1
公开(公告)日：2011-10-13
申请号：US13023722
申请日：2011-02-09
申请人： Niyazi Beyhan , Surag Mantri , Hoang Nguyen , Son Gia , Gregory Alan Pulido , Dushyant Jivanlal Shah , George Surjan , Gregory Michael Ruhf , Lutz Freitag
发明人： Niyazi Beyhan , Surag Mantri , Hoang Nguyen , Son Gia , Gregory Alan Pulido , Dushyant Jivanlal Shah , George Surjan , Gregory Michael Ruhf , Lutz Freitag
IPC分类号： A61B5/08
CPC分类号： A61M16/0463 , A61B17/12036 , A61B17/12104 , A61B17/12136 , A61B2017/00809 , A61B2017/22068 , A61F2/013 , A61F2002/016 , A61F2002/018 , A61F2230/0067 , A61F2230/008 , A61F2230/0091 , A61M16/0404 , A61M16/0406 , A61M16/0429 , A61M16/0434 , A61M16/0438 , A61M16/0443 , A61M16/0445 , A61M16/0447 , A61M16/0459 , A61M25/007 , A61M25/0074 , A61M25/0082 , A61M2025/0073 , A61M2025/0096 , A61M2025/1047 , A61M2205/0238 , A61M2205/0266 , A61M2205/11 , A61M2205/7536 , B21F45/008
摘要： Devices systems and methods are disclosed for preventing or inhibiting secretions from entering the lumen of a functional assessment catheter for the lungs, or removing collected secretions. The catheter comprises an expandable element, a cover, or an internal component configured to prevent or inhibit secretion flow into the lumen. The catheter alternatively or additionally comprises a distal end configured to facilitate air flow, absorb secretions or repel secretions away from the catheter tip. The catheter alternatively or additionally comprises an internal element such as a coilable wire, or an obturator configured to prevent secretions from being drawn into the lumen, or to actively remove the secretions. The catheter alternatively or additionally comprises an element to dry, aerate or aspirate the lung passageways.
摘要翻译：公开了用于预防或抑制分泌物进入用于肺的功能性评估导管的内腔或去除收集的分泌物的装置系统和方法。该导管包括可扩张元件，盖或构造成防止或抑制分泌物流入内腔的内部部件。替代地或另外地包括导管的导管包括构造成促进空气流动的远端，吸收分泌物或排斥远离导管尖端的分泌物。替代地或另外地，该导管包括内部元件，例如可卷绕的线，或者构造成阻止分泌物被吸入管腔中的闭塞器，或者主动地移除分泌物。替代地或另外地，导管包括用于干燥，充气或吸入肺通道的元件。

3. 发明授权

US08985099B2 Tracheostoma spacer, tracheotomy method, and device for inserting a tracheostoma spacer 有权
公开(公告)号：US08985099B2
公开(公告)日：2015-03-24
申请号：US13399309
申请日：2012-02-17
申请人： Lutz Freitag , Anthony D. Wondka
发明人： Lutz Freitag , Anthony D. Wondka
IPC分类号： A61M11/00 , A61M16/04
CPC分类号： A61M16/0468 , A61M16/0434 , A61M16/0472 , A61M16/0477 , A61M16/0488 , A61M2202/20 , A61M2205/0222 , A61M2205/0266 , A61M2202/0078
摘要： The invention relates to a tracheostoma spacer with a tubular support framework. The support framework can be expand from an initial state to a supporting state of increased diameter and has a fixing element at the ends. The tracheostoma spacer is intended for use as a spacer in a tracheostoma (an opening in the trachea). The invention further relates to a device for inserting a tracheostoma spacer into a tracheostoma with a cutting instrument in the form of a trocar, the tracheostoma spacer being able to be positioned on the shaft of said trocar. A cover sleeve is also provided which can be moved on the shaft over a tracheostoma spacer positioned there.

4. 发明申请

US20140107396A1 SYSTEMS AND METHODS FOR DELIVERING A THERAPEUTIC AGENT 审中-公开
标题翻译：用于递送治疗剂的系统和方法
公开(公告)号：US20140107396A1
公开(公告)日：2014-04-17
申请号：US13830642
申请日：2013-03-14
申请人： Lutz Freitag
发明人： Lutz Freitag
IPC分类号： A61N5/10 , A61B17/12
CPC分类号： A61N5/10 , A61B17/1204 , A61B17/12104 , A61B17/24 , A61B2017/00809 , A61B2017/242 , A61F2/2412 , A61F2/2418 , A61F2002/043 , A61F2250/0039 , A61M16/04 , A61M16/0404 , A61M16/0406 , A61M16/0434 , A61M16/14
摘要： Devices, systems, and methods for delivering a therapeutic agent to a treatment region in the body are disclosed. By determining a treatment region in the body, reducing the volume of the treatment region to create a target region by using one or more flow control elements and delivering at least one therapeutic agent to the target region, improved treatment may be achieved.
摘要翻译：公开了用于将治疗剂递送到身体中的治疗区域的装置，系统和方法。通过确定体内的治疗区域，通过使用一个或多个流量控制元件并将至少一种治疗剂递送至靶区域来减小治疗区域的体积以产生目标区域，可以实现改善的治疗。

5. 发明申请

US20110209705A1 TRACHEAL CATHETER AND PROSTHESIS AND METHOD OF RESPIRATORY SUPPORT OF A PATIENT 审中-公开
标题翻译： TRACHEAL导管和患者呼吸辅助的方法和方法
公开(公告)号：US20110209705A1
公开(公告)日：2011-09-01
申请号：US13044241
申请日：2011-03-09
申请人： Lutz Freitag
发明人： Lutz Freitag
IPC分类号： A61M16/00
CPC分类号： A61M16/12 , A61M16/0072 , A61M16/0465 , A61M16/0677 , A61M16/127 , A61M2016/0021 , A61M2016/0036 , A61M2025/0002 , A61M2202/0208 , A61M2205/106
摘要： A method and apparatus is described for supporting the respiration of a patient. The spontaneous respiration of a patient can be detected by sensors and during inhalation an additional amount of oxygen can be administered to the lungs via a jet gas current. If required, during exhalation a countercurrent can be administered to avoid collapse of the respiration paths. This therapy can be realized by an apparatus including a transtracheal catheter, an oxygen pump connected to an oxygen source, spontaneous respiration sensor(s) connected to a control unit for activating the oxygen pump and, if needed, a tracheal prosthesis. The tracheal prosthesis may include a connection for the catheter and the breath sensor(s). The tracheal prosthesis, if used, and the catheter can be dimensioned so the patient can freely breathe, cough, swallow and speak without restriction, and the system can be wearable to promote mobility.
摘要翻译：描述了一种支持患者呼吸的方法和装置。患者的自发呼吸可以由传感器检测，并且在吸入期间，可以通过喷射气流向肺施用额外量的氧。如果需要，在呼气期间可以施用逆流以避免呼吸路径的塌陷。该治疗可以通过包括经气管导管，连接到氧源的氧气泵，连接到用于启动氧气泵的控制单元的自发呼吸传感器以及如果需要的气管假体的装置来实现。气管假体可以包括用于导管和呼吸传感器的连接。气管假体（如果使用）和导管的尺寸可以使患者能够自由呼吸，咳嗽，吞咽和说话而不受限制，并且该系统可穿戴以促进移动。

6. 发明授权

US07533670B1 Systems, methods and apparatus for respiratory support of a patient 有权
标题翻译：用于患者呼吸支持的系统，方法和装置
公开(公告)号：US07533670B1
公开(公告)日：2009-05-19
申请号：US11523519
申请日：2006-09-20
申请人： Lutz Freitag , Gregory Kapust , Anthony Wondka
发明人： Lutz Freitag , Gregory Kapust , Anthony Wondka
IPC分类号： A61M16/00
CPC分类号： A61M16/0465 , A61M16/0006 , A61M16/0063 , A61M16/024 , A61M16/0468 , A61M2016/0021 , A61M2016/0027 , A61M2016/0413
摘要： Spontaneous respiration is detected by sensors. An additional amount of oxygen is administered to the lungs via a jet gas current at the end of an inhalation procedure. Breathing volume, absorption of oxygen during inhalation, and clearance of carbon dioxide during exhalation are improved. If required, the exhalation procedure of the patient can be arrested or slowed by a countercurrent to avoid a collapse of the respiration paths. An apparatus including an oxygen pump can be connected to an oxygen source and includes a tracheal prosthesis that can be connected via a catheter. The respiration detections sensors are connected to a control unit for activating the oxygen pump. The tracheal prosthesis includes a tubular support body with a connection for the catheter, and the sensors are associated with the support body. The tracheal prosthesis and jet catheter are dimensioned so the patient can freely breathe and speak without restriction.
摘要翻译：传感器检测到自发呼吸。在吸入程序结束时通过喷射气流向肺部施加额外量的氧气。吸入期间吸气量，吸氧量，呼气过程中二氧化碳清除率有所提高。如果需要，患者的呼气程序可以通过逆流来阻止或减慢，以避免呼吸路径的崩溃。包括氧气泵的装置可以连接到氧源并且包括可以经由导管连接的气管假体。呼吸检测传感器连接到用于激活氧气泵的控制单元。气管假体包括具有用于导管的连接的管状支撑体，并且传感器与支撑体相关联。气管假体和喷气导管的尺寸使患者能够自由地呼吸并且无限制地说话。

7. 发明申请

US20050061322A1 Method and arrangement for reducing the volume of a lung 审中-公开
标题翻译：降低肺容积的方法和装置
公开(公告)号：US20050061322A1
公开(公告)日：2005-03-24
申请号：US10981346
申请日：2004-11-03
申请人： Lutz Freitag
发明人： Lutz Freitag
IPC分类号： A61M16/04 , A62B7/00
CPC分类号： A61M16/04 , A61M16/0404
摘要： The invention relates to a method and an arrangement for reducing the volume of a patient's lung. A bronchial catheter (2) is introduced into a hyperexpanded lung area, and air is aspirated from there by means of an aspiration device (3). The associated segmental bronchus is then closed. According to the invention, the patient's spontaneous respiration is recorded by sensors (5), and aspiration of the air is carried out in synchrony with the patient's inhalation action. In order to prevent collapse of the associated segmental bronchus, a pressure generator is provided with which the associated segmental bronchus can be widened, by a compressed gas pulse, in synchrony with the aspiration. The pressure generator can be activated as a function of the aspirated air stream, which is monitored with a measuring device.
摘要翻译：本发明涉及一种减轻患者肺部体积的方法和装置。将支气管导管（2）引入超声肺部区域，并通过抽吸装置（3）从那里吸出空气。然后关联的节段性支气管闭合。根据本发明，患者的自发呼吸由传感器（5）记录，空气抽吸与患者的吸入动作同步进行。为了防止相关联的节段性支气管的塌陷，提供压力发生器，通过与抽吸同步的压缩气体脉冲，相关联的节段性支气管可以被加宽。压力发生器可以作为吸气空气流的功能而被激活，该气流由测量装置监控。

8. 发明申请

US20050034721A1 Tracheal catheter and prosthesis and method of respiratory support of a patient 有权
标题翻译：气管导管和假体以及患者呼吸支持的方法
公开(公告)号：US20050034721A1
公开(公告)日：2005-02-17
申请号：US10771803
申请日：2004-02-04
申请人： Lutz Freitag
发明人： Lutz Freitag
IPC分类号： A61M16/00 , A61M16/04 , A61M16/12 , A61M25/00 , A61M15/00
CPC分类号： A61M16/12 , A61M16/0072 , A61M16/0465 , A61M16/0677 , A61M16/127 , A61M2016/0021 , A61M2016/0036 , A61M2025/0002 , A61M2202/0208 , A61M2205/106
摘要： The invention is relative to a method and an apparatus for supporting the respiration of a patient and to a tracheal prosthesis. According to the invention the spontaneous respiration of a patient is detected by sensors and at the end of an inhalation procedure an additional amount of oxygen is administered to the lungs via a jet gas current. This improves the absorption of oxygen during inhalation. If required, the exhalation procedure of the patient can be arrested or slowed by a countercurrent in order to avoid a collapse of the respiration paths in this manner. This procedure is realized by an apparatus comprising an oxygen pump that can be connected to an oxygen source and comprising a tracheal prosthesis that can be connected via a catheter. The spontaneous respiration of the patient is detected by sensors connected to a control unit for activating the oxygen pump. The tracheal prosthesis comprises a tubular support body with a connection for the catheter and two of the sensors are associated with the support body. The tracheal prosthesis and the jet catheter that is integrated or can be introduced are dimensioned so that the patient can freely breath and speak without restriction.
摘要翻译：本发明涉及一种支持患者和气管假体的呼吸的方法和装置。根据本发明，患者的自发呼吸由传感器检测，并且在吸入程序结束时，额外量的氧经由喷射气流施用于肺。这可以改善吸入过程中吸氧。如果需要，可以通过逆流来阻止或减慢患者的呼气程序，以避免呼吸路径以这种方式崩溃。该过程通过包括氧气泵的设备来实现，所述氧气泵可以连接到氧气源并且包括可经由导管连接的气管假体。通过连接到用于激活氧气泵的控制单元的传感器来检测患者的自发呼吸。气管假体包括具有用于导管的连接的管状支撑体，并且两个传感器与支撑体相关联。整合或可以引入的气管假体和喷气导管的尺寸使得患者可以自由地呼吸并且无限制地说话。

9. 发明授权

US4520812A Method and apparatus for controlling a pressure level in a respirator 失效
标题翻译：用于控制呼吸器中的压力水平的方法和装置
公开(公告)号：US4520812A
公开(公告)日：1985-06-04
申请号：US479145
申请日：1983-03-28
申请人： Lutz Freitag , Michael Wendt , Franz J. Dankwart
发明人： Lutz Freitag , Michael Wendt , Franz J. Dankwart
IPC分类号： A61M16/00
CPC分类号： A61M16/0096
摘要： A method of and apparatus for producing a controlled pressure level in a respirator for human patients which is equipped with a tracheal tube 3 connected to the respirator and connectable to the trachea, comprises producing an oscillatory gas stream by means of two opposite gas jets in an attachment tube 4 which has two end openings. By controlling the pressure and/or frequency of the gas jets, a varying pressure level propagating into the tracheal tube is modulated onto the gas stream. The respirator for carrying out the method comprises two gas jet pipes 20, 21 having nozzle tips 24, 25 of which one discharges or points within the attachment tube 4 substantially in the direction of the tracheal tube 3 and the other substantially in the opposite direction.
摘要翻译：一种用于在用于人类患者的呼吸器中产生受控压力水平的方法和装置，其配备有连接到呼吸器并可连接到气管的气管管3，包括通过两个相对的气体射流产生振荡气流连接管4具有两个端部开口。通过控制气体射流的压力和/或频率，传播到气管管的变化的压力水平被调制到气流上。用于执行该方法的呼吸器包括两个具有喷嘴尖端24,25的气体喷射管道20,21，喷嘴尖端24,25基本上沿着气管管3的方向排出或指向附件管4内，而另一个基本上沿相反方向排出。

10. 发明授权

US09180270B2 Methods, systems and devices for non-invasive open ventilation with gas delivery nozzles within an outer tube 有权
标题翻译：用于非外界开放通气的方法，系统和装置，在外管内具有气体输送喷嘴
公开(公告)号：US09180270B2
公开(公告)日：2015-11-10
申请号：US12753851
申请日：2010-04-02
申请人： Gregory Kapust , Todd Allum , Anthony D. Wondka , Joseph Cipollone , Joey Aguirre , Darius Eghbal , Anthony Gerber , Lutz Freitag
发明人： Gregory Kapust , Todd Allum , Anthony D. Wondka , Joseph Cipollone , Joey Aguirre , Darius Eghbal , Anthony Gerber , Lutz Freitag
IPC分类号： A61M16/00 , A61M16/06 , A61M16/08 , A61M16/10 , A61M16/12 , A61M16/16 , A61M16/20
CPC分类号： A61M16/0883 , A61M16/0003 , A61M16/0006 , A61M16/0057 , A61M16/0069 , A61M16/0096 , A61M16/0493 , A61M16/0605 , A61M16/0622 , A61M16/0666 , A61M16/0677 , A61M16/0683 , A61M16/0688 , A61M16/0825 , A61M16/0841 , A61M16/0858 , A61M16/0875 , A61M16/101 , A61M16/107 , A61M16/127 , A61M16/16 , A61M16/201 , A61M16/208 , A61M2016/0015 , A61M2016/0021 , A61M2016/0024 , A61M2016/0661 , A61M2202/0208 , A61M2202/03 , A61M2205/0205 , A61M2205/17 , A61M2205/3334 , A61M2205/8206 , A61M2230/40 , A61M2202/0007
摘要： A non-invasive ventilation system may include at least one outer tube with a proximal lateral end of the outer tube adapted to extend to a side of a nose. The at least one outer tube may also include a throat section. At least one coupler may be located at a distal section of the outer tube for impinging at least one nostril and positioning the at least one outer tube relative to the at least one nostril. At least one jet nozzle may be positioned within the outer tube at the proximal lateral end and in fluid communication with a pressurized gas supply. At least one opening in the distal section may be adapted to be in fluid communication with the nostril. At least one aperture in the at least one outer tube may be in fluid communication with ambient air. The at least one aperture may be in proximity to the at least one jet nozzle.
摘要翻译：非侵入性通气系统可以包括至少一个外管，外管的近侧横端适于延伸到鼻的一侧。至少一个外管还可以包括喉部。至少一个联接器可以位于外管的远端部分处，用于冲击至少一个鼻孔，并且相对于至少一个鼻孔定位至少一个外管。至少一个喷嘴可以位于外管内的近端横向端并与加压气体源流体连通。远端部分中的至少一个开口可以适于与鼻孔流体连通。至少一个外管中的至少一个孔可以与环境空气流体连通。该至少一个孔口可以接近该至少一个喷嘴。

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