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1. 发明授权

US06183667B2 Titanium-and copper-containing carbon composite material and process for the production thereof 有权
标题翻译：含钛和含铜的碳复合材料及其生产方法
公开(公告)号：US06183667B2
公开(公告)日：2001-02-06
申请号：US09537661
申请日：2000-03-29
申请人： Shunichi Kubo , Jitsuji Ikeuchi , Hiroshi Tsuchiya , Yoshitaka Tomiyama , Kojiro Saito , Yoshinobu Morita , Takao Nakagawa , Yoshio Yoshihara
发明人： Shunichi Kubo , Jitsuji Ikeuchi , Hiroshi Tsuchiya , Yoshitaka Tomiyama , Kojiro Saito , Yoshinobu Morita , Takao Nakagawa , Yoshio Yoshihara
IPC分类号： H01B104
CPC分类号： C04B41/009 , B60L5/205 , B60L2200/26 , C04B41/5127 , C04B41/88 , C22C1/1036 , C22C49/14 , Y10T428/24997 , C04B41/4523 , C04B41/5133 , C04B35/52 , C04B35/83 , C04B14/386
摘要： A composite material having a carbon matrix, and a titanium-copper alloy dispersed in the carbon matrix and containing 1-80% by weight of titanium and 15.4-99% by weight of copper. The titanium-copper alloy is present in an amount of 2-85% based on a total weight of the carbon matrix and the titanium-copper alloy. The composite material may additionally contain carbon fibers dispersed in the carbon matrix. The composite material is produced by incorporating powder or melt of titanium and copper or copper alloy into a shaped body of carbon.
摘要翻译：具有碳基体的复合材料和分散在碳基体中的含有1-80重量％钛和15.4-99重量％铜的钛 - 铜合金。钛 - 铜合金以碳基质和钛 - 铜合金的总重量计为2-85％。复合材料还可以包含分散在碳基体中的碳纤维。复合材料通过将钛和铜或铜合金的粉末或熔体引入成形体的碳中来制造。

2. 发明授权

US06410560B1 Drug for relieving pain and promoting the removal of calculi in urolithiasis 失效
标题翻译：用于缓解疼痛并促进排尿结石的结石的药物
公开(公告)号：US06410560B1
公开(公告)日：2002-06-25
申请号：US09448423
申请日：1999-11-24
申请人： Masuo Akahane , Yoshitaka Tomiyama
发明人： Masuo Akahane , Yoshitaka Tomiyama
IPC分类号： A61K3147
CPC分类号： A61K31/4704 , A61K31/00 , A61K31/137 , A61K31/138 , A61K31/4184
摘要： The present invention relates to a novel drug composition for relieving pain and promoting the removal of calculi in urolithiasis which contains an active ingredient having stimulating effects on both &bgr;2- and &bgr;3-adrenoceptors and exerting a potent relaxing effect on human ureteral smooth muscle.
摘要翻译：本发明涉及一种用于缓解疼痛并促进去除尿石结石的新型药物组合物，其含有对β2-和β3-肾上腺素受体具有刺激作用的活性成分，并对人输尿管平滑肌发挥有效的缓解作用。

3. 发明授权

US5964334A Wet friction contact device 失效
标题翻译：湿摩擦接触装置
公开(公告)号：US5964334A
公开(公告)日：1999-10-12
申请号：US906610
申请日：1997-08-05
申请人： Koji Shimoda , Teikou Oobucht , Yoshitaka Tomiyama , Satoru Nakano
发明人： Koji Shimoda , Teikou Oobucht , Yoshitaka Tomiyama , Satoru Nakano
IPC分类号： F16D13/62 , C22C9/00 , C22C21/00 , C22C47/00 , C22C49/00 , C22C49/06 , F16D25/062 , F16D35/00 , F16D69/00 , F16D69/02
CPC分类号： F16D69/00 , F16D35/00 , F16D69/027 , B22F2998/00
摘要： A wet type friction contact device comprises a non-driving member; a driving member which drives to the non-driving member; and fluid which is intervened between the non-driving member and driving member; wherein the coefficient of dynamic friction of the contact area between the non-driving member and the driving member is not less than 0.2. Therefore, the present invention provides a wet type friction contact device which secures a large amount of torque capacity compared with that of the conventional wet type contact device without bringing about large-size unit thereof and also without requiring disassembly and exchange thereof.
摘要翻译：湿式摩擦接触装置包括非驱动构件; 驱动构件，其驱动到非驱动构件; 和介于非驱动构件和驱动构件之间的流体; 其中所述非驱动构件和所述驱动构件之间的接触区域的动摩擦系数不小于0.2。因此，本发明提供了一种湿式摩擦接触装置，其与常规的湿式接触装置相比确保了大量的扭矩容量，而不会导致其大尺寸单元，并且也不需要拆卸和更换。

4. 发明申请

US20110230538A1 PHARMACEUTICAL FOR USE IN THE TREATMENT OF URETEROLITHIASIS 审中-公开
标题翻译：用于治疗尿毒症的药物
公开(公告)号：US20110230538A1
公开(公告)日：2011-09-22
申请号：US13086040
申请日：2011-04-13
申请人： Mamoru Kobayashi , Yoshitaka Tomiyama , Kumi Kobayashi
发明人： Mamoru Kobayashi , Yoshitaka Tomiyama , Kumi Kobayashi
IPC分类号： A61K31/404 , A61P13/12 , A61P25/04
CPC分类号： C07D209/08 , A61K31/4045
摘要： The present invention provides pharmaceutical compositions useful for relieving pain caused by ureteral calculi, facilitating exclusion of ureteral calculi or the like. That is, the present invention provides a pharmaceutical composition for the treatment of ureteral lithiasis, which comprises as an active ingredient an indoline derivative represented by the following general formula (I) or a salt thereof. In the formula, R represents saturated or unsaturated aliphatic acyl which may have a substituent; hydroxyalkyl; aliphatic acyloxyalkyl; lower alkyl which has as a substituent lower alkoxy, carboxy, lower alkoxycarbonyl, aryl-substituted lower alkoxycarbonyl, carbamoyl, mono or di (lower alkyl)-substituted carbamoyl or cyano; optionally substituted aromatic acyl; furoyl or pyridylcarbonyl; R1 represents cyano or carbamoyl; and R2 represents lower alkyl which may have as a substituent halogen, cyano or aryl.
摘要翻译：本发明提供了用于缓解由输尿管结石引起的疼痛，有助于排除输尿管结石等的药物组合物。也就是说，本发明提供了用于治疗输尿管结石的药物组合物，其包含作为活性成分的由以下通式（I）表示的二氢吲哚衍生物或其盐。在该式中，R表示可具有取代基的饱和或不饱和脂肪族酰基; 羟烷基脂肪酰氧基烷基; 羧基，低级烷氧基羰基，芳基取代的低级烷氧基羰基，氨基甲酰基，一或二（低级烷基）取代的氨基甲酰基或氰基的低级烷基; 任选取代的芳族酰基; 糠酰基或吡啶基羰基; R1表示氰基或氨基甲酰基; 并且R 2表示可以具有卤素，氰基或芳基的取代基的低级烷基。

5. 发明申请

US20090163571A1 PHARMACEUTICAL FOR USE IN THE TREATMENT OF URETEROLITHIASIS 审中-公开
标题翻译：用于治疗尿毒症的药物
公开(公告)号：US20090163571A1
公开(公告)日：2009-06-25
申请号：US12093230
申请日：2006-11-22
申请人： Mamoru Kobayashi , Yoshitaka Tomiyama , Kumi Kobayashi
发明人： Mamoru Kobayashi , Yoshitaka Tomiyama , Kumi Kobayashi
IPC分类号： A61K31/404 , A61P13/00
CPC分类号： C07D209/08 , A61K31/4045
摘要： The present invention provides pharmaceutical compositions useful for relieving pain caused by ureteral calculi, facilitating exclusion of ureteral calculi or the like. That is, the present invention provides a pharmaceutical composition for the treatment of ureteral lithiasis, which comprises as an active ingredient an indoline derivative represented by the following general formula (I) or a salt thereof. In the formula, R represents saturated or unsaturated aliphatic acyl which may have a substituent; hydroxyalkyl; aliphatic acyloxyalkyl; lower alkyl which has as a substituent lower alkoxy, carboxy, lower alkoxycarbonyl, aryl-substituted lower alkoxycarbonyl, carbamoyl, mono or di(lower alkyl)-substituted carbamoyl or cyano; optionally substituted aromatic acyl; furoyl or pyridylcarbonyl; R1 represents cyano or carbamoyl; and R2 represents lower alkyl which may have as a substituent halogen, cyano or aryl.
摘要翻译：本发明提供了用于缓解由输尿管结石引起的疼痛，有助于排除输尿管结石等的药物组合物。也就是说，本发明提供了用于治疗输尿管结石的药物组合物，其包含作为活性成分的由以下通式（I）表示的二氢吲哚衍生物或其盐。在该式中，R表示可具有取代基的饱和或不饱和脂肪族酰基; 羟烷基; 脂肪酰氧基烷基; 羧基，低级烷氧基羰基，芳基取代的低级烷氧基羰基，氨基甲酰基，一或二（低级烷基）取代的氨基甲酰基或氰基的低级烷基; 任选取代的芳族酰基; 糠酰基或吡啶基羰基; R1表示氰基或氨基甲酰基; 并且R 2表示可以具有卤素，氰基或芳基的取代基的低级烷基。

6. 发明授权

US06376513B1 Drug for relieving pain and promoting the removal of calculi in urolithiasis 失效
标题翻译：用于缓解疼痛并促进排尿结石的结石的药物
公开(公告)号：US06376513B1
公开(公告)日：2002-04-23
申请号：US09448422
申请日：1999-11-24
申请人： Masuo Akahane , Yoshitaka Tomiyama
发明人： Masuo Akahane , Yoshitaka Tomiyama
IPC分类号： A61K3147
CPC分类号： A61K31/4704 , A61K31/00 , A61K31/137 , A61K31/138 , A61K31/4184
摘要： The present invention relates to a novel drug method for relieving pain and promoting the removal of calculi in urolithiasis which contains an active ingredient having stimulating effects on both &bgr;2- and &bgr;3-adrenoceptors and exerting a potent relaxing effect on human ureteral smooth muscle.
摘要翻译：本发明涉及一种用于缓解疼痛并促进尿石结石结石去除的新型药物方法，其包含对β2-和β3-肾上腺素受体具有刺激作用的活性成分，并对人输尿管平滑肌发挥有效的缓解作用。

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