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1. 发明授权

US06837227B2 System and method for estimating EGR mass flow and EGR fraction 有权
$System and method for estimating EGR mass flow and EGR fraction$
标题翻译：用于估算EGR质量流量和EGR分数的系统和方法
公开(公告)号：US06837227B2
公开(公告)日：2005-01-04
申请号：US09774897
申请日：2001-01-31
申请人： Salim A. Jaliwala , Paul R. Miller , Larry J. Brackney , Thomas A. Dollmeyer , Chuan He , George Brunemann , John F. Wright , Stephen J. Charlton
发明人： Salim A. Jaliwala , Paul R. Miller , Larry J. Brackney , Thomas A. Dollmeyer , Chuan He , George Brunemann , John F. Wright , Stephen J. Charlton
IPC分类号： F02B29/04 , F02D21/08 , F02M25/07 , F02B47/08
CPC分类号： F02D41/0072 , F02B29/0406 , F02B29/0493 , F02M26/05 , F02M26/23 , F02M26/33 , F02M26/47 , Y02T10/47
摘要： A system is disclosed for estimating the mass flow of recirculated exhaust gas (EGR) from an exhaust manifold to an intake manifold of an internal combustion engine via an EGR conduit disposed therebetween and a fraction of EGR attributable to a mass of charge flow entering the intake manifold. An engine controller is responsive to current values of various combinations of the engine exhaust temperature (ETE), intake manifold pressure (IMP), differential pressure (ΔP) across an EGR valve, and EGR valve position (EGRP) to determine an estimate of EGR mass flow. The controller is further operable to estimate EGR fraction as a function of the estimated EGR mass flow value, mass flow of charge entering the intake manifold, and engine speed.

2. 发明授权

US06408834B1 System for decoupling EGR flow and turbocharger swallowing capacity/efficiency control mechanisms 有权
标题翻译：用于去耦EGR流量和涡轮增压器吞吐能力/效率控制机制的系统
公开(公告)号：US06408834B1
公开(公告)日：2002-06-25
申请号：US09773654
申请日：2001-01-31
申请人： Lary J. Brackney , Thomas A. Dollmeyer , Paul R. Miller , Chuan He
发明人： Lary J. Brackney , Thomas A. Dollmeyer , Paul R. Miller , Chuan He
IPC分类号： F02M2507
CPC分类号： F02D41/0052 , F02B37/18 , F02B37/24 , F02D9/04 , F02D41/0007 , F02D41/0065 , F02D41/1401 , F02D2041/1419 , F02D2041/1422 , F02D2041/1427 , F02M26/05 , F02M26/10 , F02M26/23 , F02M26/47 , Y02T10/144 , Y02T10/47
摘要： A system for decoupling EGR flow and turbocharger swallowing capacity/efficiency control mechanisms includes a multiple-input multiple-output (MIMO) transform manager coupled to one or more of an EGR valve, an exhaust throttle and a variable geometry turbocharger (VGT) actuator of an internal combustion engine. The MIMO transform manager is responsive to commanded charge flow and EGR fraction parameters to decouple the EGR/exhaust throttle and VGT control parameters such that these control mechanisms may be controlled individually and independently of each other. One transform output is provided to a first compensator for controlling EGR flow and/or exhaust throttle operation as a function of charge flow error. The other transform output is provided to a second independent compensator for controlling VGT operation also as a function of charge flow error. Both compensators are configured to provide for transient compensator gain adjustment based on the degree of charge flow error, and the VGT compensator is further configured to provide for transient compensator gain adjustment based on a ratio of commanded fueling and oxygen/fuel ratio. The resulting control strategy provides for independent control of EGR flow/exhaust throttle and a VGT actuator, thereby resulting in better and more consistent control over mass charge flow.
摘要翻译：用于去耦EGR流和涡轮增压器吞咽能力/效率控制机构的系统包括多输入多输出（MIMO）变换管理器，其耦合到一个或多个EGR阀，排气节流阀和可变几何涡轮增压器（VGT）致动器内燃机 MIMO变换管理器响应于指令的充电流量和EGR分数参数来解耦EGR /排气节流阀和VGT控制参数，使得这些控制机构可以彼此独立地且独立地被控制。一个变换输出被提供给第一补偿器，用于控制作为电荷流动误差的函数的EGR流和/或排气节流操作。另一变换输出提供给第二独立补偿器，用于控制VGT操作，也作为充电流量误差的函数。两个补偿器被配置为基于充电流量误差的程度来提供瞬时补偿器增益调整，并且VGT补偿器还被配置为基于指令加油和氧气/燃料比的比率来提供瞬时补偿器增益调整。所得到的控制策略提供了EGR流量/排气节流阀和VGT致动器的独立控制，从而导致对质量流量的更好和更一致的控制。

3. 发明授权

US06508241B2 Equivalence ratio-based system for controlling transient fueling in an internal combustion engine 有权
标题翻译：用于控制内燃机瞬时加油的等效比系统
公开(公告)号：US06508241B2
公开(公告)日：2003-01-21
申请号：US09773068
申请日：2001-01-31
申请人： Paul R. Miller , Chuan He
发明人： Paul R. Miller , Chuan He
IPC分类号： F02D4100
CPC分类号： F02D41/0062 , F02B29/0406 , F02B29/0493 , F02D41/0072 , F02D41/1454 , F02D41/187 , F02D2200/0411 , F02M26/05 , F02M26/23 , F02M26/33 , F02M26/47 , Y02T10/47
摘要： An equivalence ratio-based system for controlling transient engine fueling includes an engine controller responsive to a number of engine operating conditions to estimate a mass of oxygen trapped within a number of cylinders of an internal combustion engine. The engine controller is further operable to map current values of engine speed and commanded fueling to one of a number of predetermined maximum fuel-to-oxygen, or equivalence, ratio values (&PHgr;MAX). The engine controller is then operable to determine an oxygen/fuel control (OFC) limited fueling command (FOFCL) as a function of the estimated oxygen mass value and the maximum equivalence ratio, and to limit engine fueling based on the OFC limited fueling command FOFCL. In one embodiment, the engine controller is operable to fuel the engine according to a minimum of the OFC limited fueling command FOFCL and a default fueling command FDEF, although other fuel limiting strategies are contemplated.
摘要翻译：用于控制瞬时发动机燃料供应的基于等效比的系统包括响应于多个发动机操作条件的发动机控制器来估计在内燃机的多个气缸内捕获的氧气的质量。发动机控制器还可操作以将发动机速度和命令的燃料供应的当前值映射到多个预定最大燃料 - 氧气或等效比值（PHIMAX）中的一个。然后，发动机控制器可操作以根据估计的氧质量值和最大当量比来确定氧/燃料控制（OFC）限制加油命令（FOFCL），并且基于OFC限制加油命令FOFCL来限制发动机加油。在一个实施例中，发动机控制器可操作以根据OFC限制加油命令FOFCL和默认加油命令FDEF的最小值来燃料发动机，尽管考虑了其他燃料限制策略。

4. 发明授权

US06543227B2 Automated active variable geometry turbocharger diagnosis system 有权
标题翻译：自动主动变量几何涡轮增压器诊断系统
公开(公告)号：US06543227B2
公开(公告)日：2003-04-08
申请号：US09774961
申请日：2001-01-31
申请人： Chuan He , Paul R. Miller
发明人： Chuan He , Paul R. Miller
IPC分类号： F02D2300
CPC分类号： F02D23/00 , F02B37/24 , F02D41/0007 , F02D41/1408 , F02D41/22 , Y02T10/144 , Y02T10/40
摘要： The present invention relates to an engine diagnostic system for detecting malfunctions in an engine system having a variable geometry turbine exhaust system. The engine diagnosis system includes an electronic control module adapted to periodically initiate a preprogrammed variable geometry turbine diagnostic routine. The diagnostic routine includes the operations of sending a sinusoidal control signal to a pressure regulator, determining the configuration of the variable geometry turbine, determining the pressure of a capsule, calculating the configuration of the variable geometry turbine as a function of the sinusoidal control signal, calculating the pressure of the capsule as a function of the sinusoidal control signal, determining if a pressure sensor is in calibration, determining if the pressure regulator is malfunctioning, determining if the variable geometry turbine position sensor is in calibration, determining if the variable geometry turbine is malfunctioning, and displaying the results of the test.
摘要翻译：本发明涉及一种用于检测具有可变几何涡轮机排气系统的发动机系统中的故障的发动机诊断系统。引擎诊断系统包括适于周期性启动预编程的可变几何涡轮诊断程序的电子控制模块。诊断程序包括将正弦控制信号发送到压力调节器，确定可变几何涡轮机的配置，确定胶囊的压力，根据正弦控制信号计算可变几何涡轮机的配置的操作，计算胶囊的压力作为正弦控制信号的函数，确定压力传感器是否在校准中，确定压力调节器是否发生故障，确定可变几何涡轮机位置传感器是否在校准中，确定可变几何涡轮机发生故障，并显示测试结果。

5. 发明授权

US06370935B1 On-line self-calibration of mass airflow sensors in reciprocating engines 有权
标题翻译：往复式发动机中质量气流传感器的在线自校准
公开(公告)号：US06370935B1
公开(公告)日：2002-04-16
申请号：US09173995
申请日：1998-10-16
申请人： Chuan He , Paul R. Miller
发明人： Chuan He , Paul R. Miller
IPC分类号： G01F2500
CPC分类号： G01F25/0007 , F02D41/0055 , F02D41/0072 , F02D41/18 , F02D41/2438 , F02D41/2441 , F02D41/2474 , F02D41/2477 , F02D2200/0402 , F02D2200/0406 , Y02T10/47
摘要： In an internal combustion engine having an exhaust gas recirculation system, a mass airflow (MAF) sensor is disposed at the air inlet to an engine cylinder. For engines with an EGR recirculation path, the sensor is upstream of that path. The MAF sensor provides signals to an engine control module (ECM) indicative of the mass airflow of the intake charge to the engine. A system and method for on-line self-recalibration of the MAF sensor and the MAF values includes comparing the sensed MAF value with an ideal MAF value obtained using data from sensors downstream from the MAF sensor. If a comparison of the sensed versus the actual MAF values reveals that the MAF sensor is out of calibration, a regression analysis is applied to several data pairs of MAF sensor output magnitude and ideal MAF value to modify the relationship between MAF sensor output and sensed MAF value.
摘要翻译：在具有废气再循环系统的内燃机中，在发动机气缸的入口处设置质量气流（MAF）传感器。对于具有EGR再循环路径的发动机，传感器位于该路径的上游。 MAF传感器向发动机控制模块（ECM）提供指示发动机进气量的质量气流的信号。用于MAF传感器和MAF值的在线自重新校准的系统和方法包括将感测的MAF值与使用来自MAF传感器下游的传感器的数据获得的理想MAF值进行比较。如果感测到的实际MAF值的比较显示MAF传感器不在校准，则回归分析被应用于MAF传感器输出幅度和理想MAF值的若干数据对，以修改MAF传感器输出和感测MAF之间的关系值。

6. 发明授权

US09611510B2 Composition and methods related to modification of 5-methylcytosine (5-mC) 有权
公开(公告)号：US09611510B2
公开(公告)日：2017-04-04
申请号：US14110007
申请日：2012-04-06
申请人： Chuan He , Liang Zhang , Chunxiao Song , Miao Yu
发明人： Chuan He , Liang Zhang , Chunxiao Song , Miao Yu
IPC分类号： C12Q1/68 , C12P19/34 , C07H21/02 , G06F19/00
CPC分类号： C12Q1/6869 , C12Q1/6827 , C12Q2521/531 , C12Q2537/164
摘要： The present invention relates to methods and compositions for detecting, evaluating, and/or mapping 5-methyl-modified and/or 5-hydroxylmethyl-modified cytosine bases within a nucleic acid molecule.

7. 发明授权

US07937996B2 Turbo speed sensor diagnostic for turbocharged engines 有权
标题翻译：用于涡轮增压发动机的Turbo速度传感器诊断
公开(公告)号：US07937996B2
公开(公告)日：2011-05-10
申请号：US12141329
申请日：2008-06-18
申请人： Chuan He , Yun Xiao
发明人： Chuan He , Yun Xiao
IPC分类号： G01M15/00
CPC分类号： F02D41/0007 , F02D41/222 , Y02T10/144 , Y02T10/40
摘要： A method of diagnosing operation of a turbo speed sensor that monitors a turbocharger in an internal combustion engine system includes determining whether the engine system is operating in one of a high speed and a low speed range and determining a threshold turbo speed value based on whether engine system is operating in one of the high speed and the low speed range. An actual turbo speed value of the turbocharger is monitored based on a signal generated by the turbo speed sensor. The actual turbo speed value is compared to the threshold turbo speed value and a diagnostic signal is generated based on the step of comparing.
摘要翻译：一种诊断内燃机系统中的涡轮增压器的涡轮速度传感器的操作的方法包括：确定发动机系统是否以高速和低速范围中的一个运行，并且基于发动机是否确定阈值涡轮转速值系统运行在高速和低速范围之一。基于由涡轮转速传感器产生的信号来监测涡轮增压器的实际涡轮转速值。将实际的turbo速度值与阈值turbo速度值进行比较，并且基于比较步骤生成诊断信号。

8. 发明申请

US20100139710A1 METHODS AND APPARATUS FOR CLEANING SEMICONDUCTOR WAFERS 有权
标题翻译：清洗半导体波形的方法和装置
公开(公告)号：US20100139710A1
公开(公告)日：2010-06-10
申请号：US12452367
申请日：2007-07-05
申请人： Hui Wang , Jian Wang , Yue Ma , Chuan He
发明人： Hui Wang , Jian Wang , Yue Ma , Chuan He
IPC分类号： B08B3/12 , B08B13/00 , B08B3/08
CPC分类号： H01L21/02041 , B08B3/12 , H01L21/02052 , H01L21/02063 , H01L21/6704 , H01L21/67051
摘要： An apparatus for cleaning a surface of wafer or substrate includes a plate being positioned with a gap to surface of the wafer or substrate, and the plate being rotated around an axis vertical to surface of wafer or substrate. The rotating plate surface facing surface of the wafer or substrate has grooves, regular patterns, and irregular patterns to enhance the cleaning efficiency. Another embodiment further includes an ultra sonic or mega sonic transducer vibrating the rotating plate during cleaning process.
摘要翻译：用于清洁晶片或基板的表面的设备包括板，其定位成与晶片或基板的表面间隔开，并且板围绕垂直于晶片或基板表面的轴线旋转。晶片或基板的旋转板表面相对表面具有凹槽，规则图案和不规则图案以提高清洁效率。另一个实施例还包括在清洁过程中振动旋转板的超声波或超声波传感器。

9. 发明申请

US20070248581A1 MGRA IS A REDOX REGULATOR OF ANTIBIOTIC SENSITIVITY AND VIRULENCE 审中-公开
标题翻译： MGRA是抗生素敏感性和毒力的REDOX调节剂
公开(公告)号：US20070248581A1
公开(公告)日：2007-10-25
申请号：US11668959
申请日：2007-01-30
申请人： Peng Chen , Chuan He
发明人： Peng Chen , Chuan He
IPC分类号： C12N1/36 , A61K35/74 , C12Q1/18 , C12Q1/68
CPC分类号： C12Q1/18 , A61K38/00 , C07K14/31 , G01N33/569 , G01N33/56938 , G01N2333/21 , G01N2333/31 , G01N2333/315 , G01N2333/32 , G01N2500/00
摘要： The present invention relates to the identification of a specific cysteine (Cys) residue in MgrA of Staphylococcus aureus and homologs in other bacteria that acts as a redox switch to regulate virulence of S. aureus and expression of bacterial genes that confer resistance to antibiotics. In addition, MgrA is found to be a key virulence determinant for S. aureus. Oxidative regulation of other Cys containing proteins in various bacteria has been observed, leading to the ability to modulate virulence and resistance of these organisms.
摘要翻译：本发明涉及鉴定金黄色葡萄球菌的MgrA中的特定半胱氨酸（Cys）残基及其它细菌中的同系物，其作为调节金黄色葡萄球菌的毒力的氧化还原转换和赋予抗生素抗性的细菌基因的表达。此外，MgrA被发现是金黄色葡萄球菌的关键毒力决定因素。已经观察到其他含有Cys的蛋白质在各种细菌中的氧化调节，导致调节这些生物体的毒力和抗性的能力。

10. 发明申请

US20050279156A1 Diesel oxidation catalyst efficiency diagnostic method 有权
标题翻译：柴油氧化催化剂效率诊断方法
公开(公告)号：US20050279156A1
公开(公告)日：2005-12-22
申请号：US11098185
申请日：2005-04-04
申请人： Chuan He , Richard Jess , Jay Tolsma , John Van Gilder , Wenbo Wang
发明人： Chuan He , Richard Jess , Jay Tolsma , John Van Gilder , Wenbo Wang
IPC分类号： F01N3/035 , F01N11/00 , F01N13/02 , F02D41/02 , F02D41/40 , G01N33/497
CPC分类号： F01N11/002 , F01N3/035 , F01N13/009 , F01N2550/02 , F01N2550/04 , F02D41/0235 , F02D41/405 , Y02T10/44 , Y02T10/47
摘要： A diesel oxidation catalyst (DOC) testing system includes a DOC that is located in an exhaust system of a vehicle. A control module verifies proper operation of the DOC during a post-fuel injection process in an engine of the vehicle. The control module computes a predicted temperature of exhaust gases at an output of the DOC that corresponds with proper operation of the DOC during the post-fuel injection process, determines an actual temperature of the exhaust gases during the post-fuel injection process, and activates an alarm indicator when a difference between the predicted temperature and the actual temperature is greater than a first predetermined value. A first temperature sensor is located downstream from the DOC in the exhaust system. The first temperature sensor communicates with the control module, generates the actual temperature, and transmits the actual temperature to the control module.
摘要翻译：柴油氧化催化剂（DOC）测试系统包括位于车辆的排气系统中的DOC。在车辆的发动机中的后燃料喷射过程中，控制模块验证DOC的正确操作。控制模块计算在燃料喷射过程中DOC对应于DOC的适当操作的DOC输出处的废气的预测温度，确定后燃料喷射过程中废气的实际温度，并激活当预测温度和实际温度之间的差大于第一预定值时的报警指示器。第一温度传感器位于排气系统中DOC的下游。第一个温度传感器与控制模块通信，产生实际温度，并将实际温度传送到控制模块。

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