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1. 发明授权

EP2725091B1 CELL STRUCTURE PRODUCTION DEVICE 有权转让
标题翻译：器具，用于产生胞状结构
公开(公告)号：EP2725091B1
公开(公告)日：2016-07-20
申请号：EP12802594.7
申请日：2012-06-19
申请人： National University Corporation Saga University , Cyfuse Biomedical K. K. , SHIBUYA KOGYO CO., LTD
发明人： NAKAYAMA, Koichi , YONEDA, Kenji , SAKAMOTO, Masahiro , KOSHIDA, Ichiro , SHOMURA, Masaharu , FUKAMURA, Isao
IPC分类号： C12M3/00 , C12M1/32 , C12M1/26 , C12M1/12
CPC分类号： C12M33/04 , C12M21/08 , C12M23/12 , C12M25/00 , C12M25/14 , C12M25/16

2. 发明公开

EP2725091A1 CELL STRUCTURE PRODUCTION DEVICE 有权转让
标题翻译： VORRICHTUNG ZUR HERSTELLUNG EINER ZELLSTRUKTUR
公开(公告)号：EP2725091A1
公开(公告)日：2014-04-30
申请号：EP12802594.7
申请日：2012-06-19
申请人： National University Incoporation Saga University , Cyfuse Biomedical K. K. , SHIBUYA KOGYO CO., LTD
发明人： NAKAYAMA, Koichi , YONEDA, Kenji , SAKAMOTO, Masahiro , KOSHIDA, Ichiro , SHOMURA, Masaharu , FUKAMURA, Isao
IPC分类号： C12M1/00 , A61L27/00 , C12N11/02
CPC分类号： C12M33/04 , C12M21/08 , C12M23/12 , C12M25/00 , C12M25/14 , C12M25/16
摘要： A device 2 for producing a three-dimensional structural body comprising an accommodating plate 3 in which an accommodating recess portion 3a for accommodating a cell mass 1 is formed, a support body 4 provided with a plurality of needle-shaped bodies 6 penetrating the cell mass, a suction nozzle 19 for adsorbing/holding the cell mass, and moving means 20 for moving the suction nozzle.
The suction nozzle is provided with a tubular adsorbing portion 19a for adsorbing/holding one cell mass, and a diameter of the adsorbing portion is formed smaller than an outer diameter of the cell mass and larger than an outer peripheral diameter of a needle-shaped body 6a of the support body 4.
When the cell mass is adsorbed/held by the adsorbing portion of the suction nozzle, the moving means moves the suction nozzle to above the needle-shaped body and further moves the suction nozzle in an axial direction of the needle-shaped body, the needle-shaped body is stuck into the cell mass, and the needle-shaped body penetrating the cell mass is inserted into the adsorbing portion.
The three-dimensional structural cell can be produced automatically.
摘要翻译：一种用于制造三维结构体的装置2，包括：容纳板3，其中形成有用于容纳电池块1的容纳凹部3a;支撑体4，其设置有穿过电池块的多个针状体6 ，用于吸附/保持电池块的吸嘴19和用于移动吸嘴的移动装置20。吸嘴设置有用于吸附/保持一个电池组的管状吸附部分19a，并且吸附部分的直径形成为小于电池组件的外径并且大于针状体的外周径当细胞块被吸嘴的吸附部分吸附/保持时，移动装置将吸嘴移动到针状体上方，并使吸嘴沿轴向方向移动针状体，将针状体粘贴到细胞块中，将穿透细胞块的针状体插入吸附部。三维结构单元可以自动生成。

3. 发明公开

EP2974751A1 CARDIAC OR VASCULAR TISSUE SPHEROID 审中-公开
标题翻译：心脏或血管组织球状体
公开(公告)号：EP2974751A1
公开(公告)日：2016-01-20
申请号：EP13878105.9
申请日：2013-10-24
申请人： Saga University , Cyfuse Biomedical K. K.
发明人： NOGUCHI, Ryo , TAMURA, Tadashi , NAKAYAMA, Koichi , MORITA, Shigeki , NODE, Koichi
IPC分类号： A61L27/00 , C12N5/071 , C12N5/077
CPC分类号： A61L27/3625 , A61K35/33 , A61K35/34 , A61K35/44 , A61L27/3804 , A61L27/3886 , A61L27/507 , A61L2300/64 , A61L2430/20 , C12N5/0691 , C12N5/0697 , C12N2502/1323 , C12N2502/1329 , C12N2502/28
摘要： Provided is a method for producing a cardiac tissue spheroid or vascular tissue spheroid formed from a mixture of a myocardial cell or smooth muscle cell and at least one type of cell selected from a vascular endothelial cell and fibroblast, and a three dimensional cardiac tissue structure or three dimensional vascular tissue structure which are characterized by combining or laminating said spheroid.
摘要翻译：提供一种由心肌细胞或平滑肌细胞与选自血管内皮细胞和成纤维细胞中的至少一种细胞和三维心脏组织结构的混合物形成的心脏组织球体或血管组织球体的制造方法，或者三维维管组织结构，其特征在于组合或层压所述球体。

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