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1. 发明申请

WO2014152048A2 ASSEMBLIES AND METHODS FOR REDUCING OPTICAL CROSSTALK IN PARTICLE PROCESSING SYSTEMS 审中-公开
标题翻译：用于减少粒子处理系统中光学串扰的组件和方法
公开(公告)号：WO2014152048A2
公开(公告)日：2014-09-25
申请号：PCT/US2014/026877
申请日：2014-03-13
申请人： CYTONOME/ST, LLC
发明人： SHARPE, Johnathan, Charles , PERRAULT, Donald, Frances, Jr. , MACHADO, Emanuel Tito, Mendes , MORAD, Blair, D.
IPC分类号： G01N15/14
CPC分类号： G01N15/1434 , G01N15/10 , G01N15/14 , G01N15/1429
摘要： The present disclosure relates to optical crosstalk reduction in particle processing (e.g., cytometry including flow cytometry using microfluidic based sorters, drop formation based sorters, and/or cell purification) systems and methods in order to improve performance. More particularly, the present disclosure relates to assemblies, systems and methods for minimizing optical crosstalk during the analyzing, sorting, and/or processing (e.g., purifying, measuring, isolating, detecting, monitoring and/or enriching) of particles (e.g., cells, microscopic particles, etc.). The exemplary systems and methods for crosstalk reduction in particle processing systems (e.g., cell purification systems) may be particularly useful in the area of cellular medicine or the like. The systems and methods may be modular and used singly or in combination to optimize cell purification based on the crosstalk environment and specific requirements of the operator and/or system.
摘要翻译：本公开涉及粒子加工中的光学串扰减少（例如，包括使用基于微流体分选器的流式细胞术的流式细胞仪，基于液滴形成的分选器和/或细胞纯化）系统和方法以改善性能。更具体地说，本公开涉及用于在分析，分选和/或处理颗粒（例如，细胞）的过程（例如纯化，测量，分离，检测，监测和/或富集）期间最小化光学串扰的组件，系统和方法。，微观颗粒等）。用于在粒子处理系统（例如细胞纯化系统）中减少串扰的示例性系统和方法可能在细胞医学等领域特别有用。该系统和方法可以是模块化的并且可以单独使用或组合使用，以基于串扰环境和操作员和/或系统的特定要求来优化细胞净化。

2. 发明公开

EP4134656A1 ASSEMBLIES AND METHODS FOR REDUCING OPTICAL CROSSTALK IN PARTICLE PROCESSING SYSTEMS 审中-实审
公开(公告)号：EP4134656A1
公开(公告)日：2023-02-15
申请号：EP22196397.8
申请日：2014-03-13
申请人： Cytonome/ST, LLC
发明人： SHARPE, Johnathan, Charles , PERRAULT, Donald, Frances, Jr. , MACHADO, Emanuel Tito, Mendes , MORAD, Blair, D.
IPC分类号： G01N15/14
摘要： The present disclosure relates to optical crosstalk reduction in particle processing (e.g., cytometry including flow cytometry using microfluidic based sorters, drop formation based sorters, and/or cell purification) systems and methods in order to improve performance. More particularly, the present disclosure relates to assemblies, systems and methods for minimizing optical crosstalk during the analyzing, sorting, and/or processing (e.g., purifying, measuring, isolating, detecting, monitoring and/or enriching) of particles (e.g., cells, microscopic particles, etc.). The exemplary systems and methods for crosstalk reduction in particle processing systems (e.g., cell purification systems) may be particularly useful in the area of cellular medicine or the like. The systems and methods may be modular and used singly or in combination to optimize cell purification based on the crosstalk environment and specific requirements of the operator and/or system.

3. 发明公开

EP2972207A2 ASSEMBLIES AND METHODS FOR REDUCING OPTICAL CROSSTALK IN PARTICLE PROCESSING SYSTEMS 有权转让
标题翻译：安排和方法降低了光关于操着颗粒加工系统
公开(公告)号：EP2972207A2
公开(公告)日：2016-01-20
申请号：EP14720364.0
申请日：2014-03-13
申请人： Cytonome/ST, LLC
发明人： SHARPE, Johnathan, Charles , PERRAULT, Donald, Frances, Jr. , MACHADO, Emanuel Tito, Mendes , MORAD, Blair, D.
IPC分类号： G01N15/14
CPC分类号： G01N15/1434 , G01N15/10 , G01N15/14 , G01N15/1429
摘要： The present disclosure relates to optical crosstalk reduction in particle processing (e.g., cytometry including flow cytometry using microfluidic based sorters, drop formation based sorters, and/or cell purification) systems and methods in order to improve performance. More particularly, the present disclosure relates to assemblies, systems and methods for minimizing optical crosstalk during the analyzing, sorting, and/or processing (e.g., purifying, measuring, isolating, detecting, monitoring and/or enriching) of particles (e.g., cells, microscopic particles, etc.). The exemplary systems and methods for crosstalk reduction in particle processing systems (e.g., cell purification systems) may be particularly useful in the area of cellular medicine or the like. The systems and methods may be modular and used singly or in combination to optimize cell purification based on the crosstalk environment and specific requirements of the operator and/or system.
摘要翻译：本公开涉及到在粒子处理光学串扰减少（E. G.流式细胞仪包括流式细胞仪使用基于微流体分选器，滴基于形成分拣机，和/或细胞纯化），以提高性能的系统和方法。更具体地，本公开涉及组件，系统以及用于该分析过程中最小化的光学串扰，分选方法，和/或处理（例如，净化，测量，分离，检测，监视和/或富集的）颗粒（例如，细胞，微观粒子，等）。示例性系统和用于在粒子处理系统的串扰减少（E. G.，细胞纯化系统）的方法可以是在细胞药物或类似的区域是特别有用的。该系统和方法可以是模块化的，并用于单独或组合基于所述串扰环境和操作者和/或系统的具体要求，以优化细胞纯化。

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